Mary C Horne

Title(s)Adjunct Professor, Med: Pharmacology
SchoolSchool of Medicine
Address2219B Tupper Hall
CA 95616
Phone530-752-7723
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. 14-3-3 promotes sarcolemmal expression of cardiac CaV1.2 and nucleates isoproterenol-triggered channel superclustering. Proc Natl Acad Sci U S A. 2025 Feb 04; 122(5):e2413308122. Spooner HC, Costa AD, Westhoff M, Hernández-González A, Ibrahimkhail H, Yarov-Yarovoy V, Horne MC, Dickson EJ, Dixon RE. PMID: 39869803; PMCID: PMC11804677.
      View in: PubMed   Mentions:    Fields:    
    2. α1C S1928 Phosphorylation of CaV1.2 Channel Controls Vascular Reactivity and Blood Pressure. J Am Heart Assoc. 2024 Oct 15; 13(20):e035375. Flores-Tamez VA, Martín-Aragón Baudel M, Hong J, Taylor JL, Ren L, Le T, Syed AU, Moustafa Y, Singhrao N, Lemus-Martinez WR, Reddy GR, Ramer V, Man KNM, Bartels P, Chen-Izu Y, Chen CY, Simo S, Dickson EJ, Morotti S, Grandi E, Santana LF, Hell JW, Horne MC, Nieves-Cintrón M, Navedo MF. PMID: 39377203; PMCID: PMC11935578.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    3. α1-Adrenergic receptor-PKC-Pyk2-Src signaling boosts L-type Ca2+ channel CaV1.2 activity and long-term potentiation in rodents. Elife. 2023 Jun 20; 12. Man KNM, Bartels P, Henderson PB, Kim K, Shi M, Zhang M, Ho SY, Nieves-Cintron M, Navedo MF, Horne MC, Hell JW. PMID: 37338965; PMCID: PMC10325713.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    4. Acute phosphatidylinositol 4,5 bisphosphate depletion destabilizes sarcolemmal expression of cardiac L-type Ca2+ channel CaV1.2. Proc Natl Acad Sci U S A. 2023 04 04; 120(14):e2221242120. Voelker TL, Del Villar SG, Westhoff M, Costa AD, Coleman AM, Hell JW, Horne MC, Dickson EJ, Dixon RE. PMID: 36976770; PMCID: PMC10083594.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    5. Half-calcified calmodulin promotes basal activity and inactivation of the L-type calcium channel CaV1.2. J Biol Chem. 2022 12; 298(12):102701. Bartels P, Salveson I, Coleman AM, Anderson DE, Jeng G, Estrada-Tobar ZM, Man KNM, Yu Q, Kuzmenkina E, Nieves-Cintron M, Navedo MF, Horne MC, Hell JW, Ames JB. PMID: 36395884; PMCID: PMC9764201.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    6. Tissue-specific adrenergic regulation of the L-type Ca2+ channel CaV1.2. Sci Signal. 2020 12 22; 13(663). Man KNM, Bartels P, Horne MC, Hell JW. PMID: 33443233; PMCID: PMC7909005.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    7. α-Actinin-1 promotes activity of the L-type Ca2+ channel Cav1.2. EMBO J. 2020 Sep 15; 39(18):e106171. Turner M, Anderson DE, Bartels P, Nieves-Cintron M, Coleman AM, Henderson PB, Man KNM, Tseng PY, Yarov-Yarovoy V, Bers DM, Navedo MF, Horne MC, Ames JB, Hell JW. PMID: 33433005; PMCID: PMC7507692.
      View in: PubMed   Mentions: 3     Fields:    
    8. α-Actinin-1 promotes activity of the L-type Ca2+ channel Cav 1.2. EMBO J. 2020 03 02; 39(5):e102622. Turner M, Anderson DE, Bartels P, Nieves-Cintron M, Coleman AM, Henderson PB, Man KNM, Tseng PY, Yarov-Yarovoy V, Bers DM, Navedo MF, Horne MC, Ames JB, Hell JW. PMID: 31985069; PMCID: PMC7049811.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    9. β2 Adrenergic Receptor Complexes with the L-Type Ca2+ Channel CaV1.2 and AMPA-Type Glutamate Receptors: Paradigms for Pharmacological Targeting of Protein Interactions. Annu Rev Pharmacol Toxicol. 2020 01 06; 60:155-174. Man KNM, Navedo MF, Horne MC, Hell JW. PMID: 31561738; PMCID: PMC7029424.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    10. Dynamic L-type CaV1.2 channel trafficking facilitates CaV1.2 clustering and cooperative gating. Biochim Biophys Acta Mol Cell Res. 2018 09; 1865(9):1341-1355. Ghosh D, Nieves-Cintrón M, Tajada S, Brust-Mascher I, Horne MC, Hell JW, Dixon RE, Santana LF, Navedo MF. PMID: 29959960; PMCID: PMC6407617.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    11. α-Actinin Anchors PSD-95 at Postsynaptic Sites. Neuron. 2018 03 07; 97(5):1094-1109.e9. Matt L, Kim K, Hergarden AC, Patriarchi T, Malik ZA, Park DK, Chowdhury D, Buonarati OR, Henderson PB, Gökçek Saraç Ç, Zhang Y, Mohapatra D, Horne MC, Ames JB, Hell JW. PMID: 29429936; PMCID: PMC5963734.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    12. Proteolytic processing of the L-type Ca 2+ channel alpha 11.2 subunit in neurons. F1000Res. 2017; 6:1166. Buonarati OR, Henderson PB, Murphy GG, Horne MC, Hell JW. PMID: 28781760; PMCID: PMC5531164.
      View in: PubMed   Mentions: 18     Fields:    
    13. α-Actinin Promotes Surface Localization and Current Density of the Ca2+ Channel CaV1.2 by Binding to the IQ Region of the α1 Subunit. Biochemistry. 2017 07 18; 56(28):3669-3681. Tseng PY, Henderson PB, Hergarden AC, Patriarchi T, Coleman AM, Lillya MW, Montagut-Bordas C, Lee B, Hell JW, Horne MC. PMID: 28613835; PMCID: PMC5704914.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    14. Angiotensin II signalling kicks out p27Kip1 : casein kinase 2 augmentation of Cav 1.2 L-type Ca2+ channel activity in immature ventricular cardiomyocytes. J Physiol. 2017 07 01; 595(13):4131-4132. Horne MC, Hell JW. PMID: 28488737; PMCID: PMC5491853.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    15. Cyclin G2 promotes cell cycle arrest in breast cancer cells responding to fulvestrant and metformin and correlates with patient survival. Cell Cycle. 2016 Dec; 15(23):3278-3295. Zimmermann M, Arachchige-Don AP, Donaldson MS, Patriarchi T, Horne MC. PMID: 27753529; PMCID: PMC5176157.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    16. Down-regulation of cyclin G2 by insulin, IGF-I (insulin-like growth factor 1) and X10 (AspB10 insulin): role in mitogenesis. Biochem J. 2014 Jan 01; 457(1):69-77. Svendsen AM, Winge SB, Zimmermann M, Lindvig AB, Warzecha CB, Sajid W, Horne MC, De Meyts P. PMID: 24059861.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    17. Elevated cyclin G2 expression intersects with DNA damage checkpoint signaling and is required for a potent G2/M checkpoint arrest response to doxorubicin. J Biol Chem. 2012 Jun 29; 287(27):22838-53. Zimmermann M, Arachchige-Don AS, Donaldson MS, Dallapiazza RF, Cowan CE, Horne MC. PMID: 22589537; PMCID: PMC3391138.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    18. Targeting of protein phosphatases PP2A and PP2B to the C-terminus of the L-type calcium channel Ca v1.2. Biochemistry. 2010 Dec 07; 49(48):10298-307. Xu H, Ginsburg KS, Hall DD, Zimmermann M, Stein IS, Zhang M, Tandan S, Hill JA, Horne MC, Bers D, Hell JW. PMID: 21053940; PMCID: PMC3075818.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    19. mTOR supports long-term self-renewal and suppresses mesoderm and endoderm activities of human embryonic stem cells. Proc Natl Acad Sci U S A. 2009 May 12; 106(19):7840-5. Zhou J, Su P, Wang L, Chen J, Zimmermann M, Genbacev O, Afonja O, Horne MC, Tanaka T, Duan E, Fisher SJ, Liao J, Chen J, Wang F. PMID: 19416884; PMCID: PMC2683106.
      View in: PubMed   Mentions: 117     Fields:    Translation:HumansCells
    20. Roles of human epidermal growth factor receptor 2, c-jun NH2-terminal kinase, phosphoinositide 3-kinase, and p70 S6 kinase pathways in regulation of cyclin G2 expression in human breast cancer cells. Mol Cancer Ther. 2007 Nov; 6(11):2843-57. Le XF, Arachchige-Don AS, Mao W, Horne MC, Bast RC. PMID: 18025271.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    21. Chromosomal instability and supernumerary centrosomes represent precursor defects in a mouse model of T-cell lymphoma. Cancer Res. 2007 Sep 01; 67(17):8081-8. van de Wetering CI, Horne MC, Knudson CM. PMID: 17804719.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    22. Cyclin G2 is a centrosome-associated nucleocytoplasmic shuttling protein that influences microtubule stability and induces a p53-dependent cell cycle arrest. Exp Cell Res. 2006 Dec 10; 312(20):4181-204. Arachchige Don AS, Dallapiazza RF, Bennin DA, Brake T, Cowan CE, Horne MC. PMID: 17123511; PMCID: PMC1862360.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    23. Binding of protein phosphatase 2A to the L-type calcium channel Cav1.2 next to Ser1928, its main PKA site, is critical for Ser1928 dephosphorylation. Biochemistry. 2006 Mar 14; 45(10):3448-59. Hall DD, Feekes JA, Arachchige Don AS, Shi M, Hamid J, Chen L, Strack S, Zamponi GW, Horne MC, Hell JW. PMID: 16519540.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    24. Cyclin G1 has growth inhibitory activity linked to the ARF-Mdm2-p53 and pRb tumor suppressor pathways. Mol Cancer Res. 2003 Jan; 1(3):195-206. Zhao L, Samuels T, Winckler S, Korgaonkar C, Tompkins V, Horne MC, Quelle DE. PMID: 12556559.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    25. Cyclin G2 associates with protein phosphatase 2A catalytic and regulatory B' subunits in active complexes and induces nuclear aberrations and a G1/S phase cell cycle arrest. J Biol Chem. 2002 Jul 26; 277(30):27449-67. Bennin DA, Don AS, Brake T, McKenzie JL, Rosenbaum H, Ortiz L, DePaoli-Roach AA, Horne MC. PMID: 11956189.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansAnimalsCells
    26. A beta2 adrenergic receptor signaling complex assembled with the Ca2+ channel Cav1.2. Science. 2001 Jul 06; 293(5527):98-101. Davare MA, Avdonin V, Hall DD, Peden EM, Burette A, Weinberg RJ, Horne MC, Hoshi T, Hell JW. PMID: 11441182.
      View in: PubMed   Mentions: 191     Fields:    Translation:HumansAnimalsCells
    27. Protein phosphatase 2A is associated with class C L-type calcium channels (Cav1.2) and antagonizes channel phosphorylation by cAMP-dependent protein kinase. J Biol Chem. 2000 Dec 15; 275(50):39710-7. Davare MA, Horne MC, Hell JW. PMID: 10984483.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansAnimalsCells
    28. Calcium/calmodulin-dependent protein kinase II is associated with the N-methyl-D-aspartate receptor. Proc Natl Acad Sci U S A. 1999 Mar 16; 96(6):3239-44. Leonard AS, Lim IA, Hemsworth DE, Horne MC, Hell JW. PMID: 10077668; PMCID: PMC15926.
      View in: PubMed   Mentions: 152     Fields:    Translation:AnimalsCells
    29. SAP97 is associated with the alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor GluR1 subunit. J Biol Chem. 1998 Jul 31; 273(31):19518-24. Leonard AS, Davare MA, Horne MC, Garner CC, Hell JW. PMID: 9677374.
      View in: PubMed   Mentions: 150     Fields:    Translation:AnimalsCells
    30. Cyclin G2 is up-regulated during growth inhibition and B cell antigen receptor-mediated cell cycle arrest. J Biol Chem. 1997 May 09; 272(19):12650-61. Horne MC, Donaldson KL, Goolsby GL, Tran D, Mulheisen M, Hell JW, Wahl AF. PMID: 9139721.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    31. Cyclin G1 and cyclin G2 comprise a new family of cyclins with contrasting tissue-specific and cell cycle-regulated expression. J Biol Chem. 1996 Mar 15; 271(11):6050-61. Horne MC, Goolsby GL, Donaldson KL, Tran D, Neubauer M, Wahl AF. PMID: 8626390.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    32. Assembly of the truncated immunoglobulin heavy chain D mu into antigen receptor-like complexes in pre-B cells but not in B cells. Immunity. 1996 Feb; 4(2):145-58. Horne MC, Roth PE, DeFranco AL. PMID: 8624805.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    33. Heterologous in vitro transcription from two archaebacterial promoters. FEBS Lett. 1991 Jul 22; 285(2):257-9. Hüdepohl U, Gropp F, Horne M, Zillig W. PMID: 1906812.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    34. A DNA region of 9 kbp contains all genes necessary for gas vesicle synthesis in halophilic archaebacteria. Mol Microbiol. 1991 May; 5(5):1159-74. Horne M, Englert C, Wimmer C, Pfeifer F. PMID: 1956294.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    35. Expression of the major gas vesicle protein gene in the halophilic archaebacterium Haloferax mediterranei is modulated by salt. Mol Gen Genet. 1990 Jul; 222(2-3):225-32. Englert C, Horne M, Pfeifer F. PMID: 1703266.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    36. Expression of two gas vacuole protein genes in Halobacterium halobium and other related species. Mol Gen Genet. 1989 Sep; 218(3):437-44. Horne M, Pfeifer F. PMID: 2586485.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    37. Genome structure of Halobacterium halobium: plasmid dynamics in gas vacuole deficient mutants. Can J Microbiol. 1989 Jan; 35(1):96-100. Pfeifer F, Blaseio U, Horne M. PMID: 2541880.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    38. Two genes encoding gas vacuole proteins in Halobacterium halobium. Mol Gen Genet. 1988 Aug; 213(2-3):459-64. Horne M, Englert C, Pfeifer F. PMID: 3185512.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
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