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Mary C Horne

Title(s)Associate Adjunct Professor, Pharmacology
SchoolUniversity of California, Davis
Phone530-752-7723
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Man KNM, Navedo MF, Horne MC, Hell JW. ß2 Adrenergic Receptor Complexes with the L-Type Ca2+ Channel CaV1.2 and AMPA-Type Glutamate Receptors: Paradigms for Pharmacological Targeting of Protein Interactions. Annu Rev Pharmacol Toxicol. 2019 Sep 27. PMID: 31561738.
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    2. Ghosh D, Nieves-Cintrón M, Tajada S, Brust-Mascher I, Horne MC, Hell JW, Dixon RE, Santana LF, Navedo MF. Dynamic L-type CaV1.2 channel trafficking facilitates CaV1.2 clustering and cooperative gating. Biochim Biophys Acta Mol Cell Res. 2018 09; 1865(9):1341-1355. PMID: 29959960.
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    3. Matt L, Kim K, Hergarden AC, Patriarchi T, Malik ZA, Park DK, Chowdhury D, Buonarati OR, Henderson PB, Gökçek Saraç Ç, Zhang Y, Mohapatra D, Horne MC, Ames JB, Hell JW. a-Actinin Anchors PSD-95 at Postsynaptic Sites. Neuron. 2018 03 07; 97(5):1094-1109.e9. PMID: 29429936.
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    4. Buonarati OR, Henderson PB, Murphy GG, Horne MC, Hell JW. Proteolytic processing of the L-type Ca 2+ channel alpha 11.2 subunit in neurons. F1000Res. 2017; 6:1166. PMID: 28781760.
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    5. Tseng PY, Henderson PB, Hergarden AC, Patriarchi T, Coleman AM, Lillya MW, Montagut-Bordas C, Lee B, Hell JW, Horne MC. a-Actinin Promotes Surface Localization and Current Density of the Ca2+ Channel CaV1.2 by Binding to the IQ Region of the a1 Subunit. Biochemistry. 2017 07 18; 56(28):3669-3681. PMID: 28613835.
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    6. Horne MC, Hell JW. Angiotensin II signalling kicks out p27Kip1 : casein kinase 2 augmentation of Cav 1.2 L-type Ca2+ channel activity in immature ventricular cardiomyocytes. J Physiol. 2017 07 01; 595(13):4131-4132. PMID: 28488737.
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    7. Zimmermann M, Arachchige-Don AP, Donaldson MS, Patriarchi T, Horne MC. Cyclin G2 promotes cell cycle arrest in breast cancer cells responding to fulvestrant and metformin and correlates with patient survival. Cell Cycle. 2016 Dec; 15(23):3278-3295. PMID: 27753529.
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    8. Svendsen AM, Winge SB, Zimmermann M, Lindvig AB, Warzecha CB, Sajid W, Horne MC, De Meyts P. Down-regulation of cyclin G2 by insulin, IGF-I (insulin-like growth factor 1) and X10 (AspB10 insulin): role in mitogenesis. Biochem J. 2014 Jan 01; 457(1):69-77. PMID: 24059861.
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    9. Zimmermann M, Arachchige-Don AS, Donaldson MS, Dallapiazza RF, Cowan CE, Horne MC. Elevated cyclin G2 expression intersects with DNA damage checkpoint signaling and is required for a potent G2/M checkpoint arrest response to doxorubicin. J Biol Chem. 2012 Jun 29; 287(27):22838-53. PMID: 22589537.
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    10. Xu H, Ginsburg KS, Hall DD, Zimmermann M, Stein IS, Zhang M, Tandan S, Hill JA, Horne MC, Bers D, Hell JW. Targeting of protein phosphatases PP2A and PP2B to the C-terminus of the L-type calcium channel Ca v1.2. Biochemistry. 2010 Dec 07; 49(48):10298-307. PMID: 21053940.
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    11. Zhou J, Su P, Wang L, Chen J, Zimmermann M, Genbacev O, Afonja O, Horne MC, Tanaka T, Duan E, Fisher SJ, Liao J, Chen J, Wang F. mTOR supports long-term self-renewal and suppresses mesoderm and endoderm activities of human embryonic stem cells. Proc Natl Acad Sci U S A. 2009 May 12; 106(19):7840-5. PMID: 19416884.
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    12. Le XF, Arachchige-Don AS, Mao W, Horne MC, Bast RC. Roles of human epidermal growth factor receptor 2, c-jun NH2-terminal kinase, phosphoinositide 3-kinase, and p70 S6 kinase pathways in regulation of cyclin G2 expression in human breast cancer cells. Mol Cancer Ther. 2007 Nov; 6(11):2843-57. PMID: 18025271.
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    13. van de Wetering CI, Horne MC, Knudson CM. Chromosomal instability and supernumerary centrosomes represent precursor defects in a mouse model of T-cell lymphoma. Cancer Res. 2007 Sep 01; 67(17):8081-8. PMID: 17804719.
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    14. Arachchige Don AS, Dallapiazza RF, Bennin DA, Brake T, Cowan CE, Horne MC. Cyclin G2 is a centrosome-associated nucleocytoplasmic shuttling protein that influences microtubule stability and induces a p53-dependent cell cycle arrest. Exp Cell Res. 2006 Dec 10; 312(20):4181-204. PMID: 17123511.
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    15. Hall DD, Feekes JA, Arachchige Don AS, Shi M, Hamid J, Chen L, Strack S, Zamponi GW, Horne MC, Hell JW. Binding of protein phosphatase 2A to the L-type calcium channel Cav1.2 next to Ser1928, its main PKA site, is critical for Ser1928 dephosphorylation. Biochemistry. 2006 Mar 14; 45(10):3448-59. PMID: 16519540.
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    16. Zhao L, Samuels T, Winckler S, Korgaonkar C, Tompkins V, Horne MC, Quelle DE. Cyclin G1 has growth inhibitory activity linked to the ARF-Mdm2-p53 and pRb tumor suppressor pathways. Mol Cancer Res. 2003 Jan; 1(3):195-206. PMID: 12556559.
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    17. Bennin DA, Don AS, Brake T, McKenzie JL, Rosenbaum H, Ortiz L, DePaoli-Roach AA, Horne MC. Cyclin G2 associates with protein phosphatase 2A catalytic and regulatory B' subunits in active complexes and induces nuclear aberrations and a G1/S phase cell cycle arrest. J Biol Chem. 2002 Jul 26; 277(30):27449-67. PMID: 11956189.
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    18. Davare MA, Avdonin V, Hall DD, Peden EM, Burette A, Weinberg RJ, Horne MC, Hoshi T, Hell JW. A beta2 adrenergic receptor signaling complex assembled with the Ca2+ channel Cav1.2. Science. 2001 Jul 06; 293(5527):98-101. PMID: 11441182.
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    19. Davare MA, Horne MC, Hell JW. Protein phosphatase 2A is associated with class C L-type calcium channels (Cav1.2) and antagonizes channel phosphorylation by cAMP-dependent protein kinase. J Biol Chem. 2000 Dec 15; 275(50):39710-7. PMID: 10984483.
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    20. Leonard AS, Lim IA, Hemsworth DE, Horne MC, Hell JW. Calcium/calmodulin-dependent protein kinase II is associated with the N-methyl-D-aspartate receptor. Proc Natl Acad Sci U S A. 1999 Mar 16; 96(6):3239-44. PMID: 10077668.
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    21. Leonard AS, Davare MA, Horne MC, Garner CC, Hell JW. SAP97 is associated with the alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor GluR1 subunit. J Biol Chem. 1998 Jul 31; 273(31):19518-24. PMID: 9677374.
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    22. Horne MC, Donaldson KL, Goolsby GL, Tran D, Mulheisen M, Hell JW, Wahl AF. Cyclin G2 is up-regulated during growth inhibition and B cell antigen receptor-mediated cell cycle arrest. J Biol Chem. 1997 May 09; 272(19):12650-61. PMID: 9139721.
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    23. Horne MC, Goolsby GL, Donaldson KL, Tran D, Neubauer M, Wahl AF. Cyclin G1 and cyclin G2 comprise a new family of cyclins with contrasting tissue-specific and cell cycle-regulated expression. J Biol Chem. 1996 Mar 15; 271(11):6050-61. PMID: 8626390.
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    24. Horne MC, Roth PE, DeFranco AL. Assembly of the truncated immunoglobulin heavy chain D mu into antigen receptor-like complexes in pre-B cells but not in B cells. Immunity. 1996 Feb; 4(2):145-58. PMID: 8624805.
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    25. Hüdepohl U, Gropp F, Horne M, Zillig W. Heterologous in vitro transcription from two archaebacterial promoters. FEBS Lett. 1991 Jul 22; 285(2):257-9. PMID: 1906812.
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    26. Horne M, Englert C, Wimmer C, Pfeifer F. A DNA region of 9 kbp contains all genes necessary for gas vesicle synthesis in halophilic archaebacteria. Mol Microbiol. 1991 May; 5(5):1159-74. PMID: 1956294.
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    27. Englert C, Horne M, Pfeifer F. Expression of the major gas vesicle protein gene in the halophilic archaebacterium Haloferax mediterranei is modulated by salt. Mol Gen Genet. 1990 Jul; 222(2-3):225-32. PMID: 1703266.
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    28. Horne M, Pfeifer F. Expression of two gas vacuole protein genes in Halobacterium halobium and other related species. Mol Gen Genet. 1989 Sep; 218(3):437-44. PMID: 2586485.
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    29. Pfeifer F, Blaseio U, Horne M. Genome structure of Halobacterium halobium: plasmid dynamics in gas vacuole deficient mutants. Can J Microbiol. 1989 Jan; 35(1):96-100. PMID: 2541880.
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    30. Horne M, Englert C, Pfeifer F. Two genes encoding gas vacuole proteins in Halobacterium halobium. Mol Gen Genet. 1988 Aug; 213(2-3):459-64. PMID: 3185512.
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