Loading...

Luis Fernando Santana

Title(s)Professor, Physiology and Membrane Biology
SchoolUniversity of California, Davis
vCardDownload vCard

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Syed AU, Reddy GR, Ghosh D, Prada MP, Nystoriak MA, Morotti S, Grandi E, Sirish P, Chiamvimonvat N, Hell JW, Santana LF, Xiang YK, Nieves-Cintrón M, Navedo MF. Adenylyl cyclase 5-generated cAMP controls cerebral vascular reactivity during diabetic hyperglycemia. J Clin Invest. 2019 06 04; 129(8):3140-3152. PMID: 31162142.
      View in: PubMed
    2. Prada MP, Syed AU, Buonarati OR, Reddy GR, Nystoriak MA, Ghosh D, Simó S, Sato D, Sasse KC, Ward SM, Santana LF, Xiang YK, Hell JW, Nieves-Cintrón M, Navedo MF. A Gs-coupled purinergic receptor boosts Ca2+ influx and vascular contractility during diabetic hyperglycemia. Elife. 2019 Mar 01; 8. PMID: 30821687.
      View in: PubMed
    3. De La Mata A, Tajada S, O'Dwyer S, Matsumoto C, Dixon RE, Hariharan N, Moreno CM, Santana LF. BIN1 Induces the Formation of T-Tubules and Adult-Like Ca2+ Release Units in Developing Cardiomyocytes. Stem Cells. 2019 01; 37(1):54-64. PMID: 30353632.
      View in: PubMed
    4. Smith FD, Omar MH, Nygren PJ, Soughayer J, Hoshi N, Lau HT, Snyder CG, Branon TC, Ghosh D, Langeberg LK, Ting AY, Santana LF, Ong SE, Navedo MF, Scott JD. Single nucleotide polymorphisms alter kinase anchoring and the subcellular targeting of A-kinase anchoring proteins. Proc Natl Acad Sci U S A. 2018 12 04; 115(49):E11465-E11474. PMID: 30455320.
      View in: PubMed
    5. Ghosh D, Nieves-Cintrón M, Tajada S, Brust-Mascher I, Horne MC, Hell JW, Dixon RE, Santana LF, Navedo MF. Dynamic L-type CaV1.2 channel trafficking facilitates CaV1.2 clustering and cooperative gating. Biochim Biophys Acta Mol Cell Res. 2018 09; 1865(9):1341-1355. PMID: 29959960.
      View in: PubMed
    6. Sato D, Dixon RE, Santana LF, Navedo MF. A model for cooperative gating of L-type Ca2+ channels and its effects on cardiac alternans dynamics. PLoS Comput Biol. 2018 01; 14(1):e1005906. PMID: 29338006.
      View in: PubMed
    7. Gentil BJ, O'Ferrall E, Chalk C, Santana LF, Durham HD, Massie R. A New Mutation in FIG4 Causes a Severe Form of CMT4J Involving TRPV4 in the Pathogenic Cascade. J Neuropathol Exp Neurol. 2017 Sep 01; 76(9):789-799. PMID: 28859335.
      View in: PubMed
    8. Vivas O, Moreno CM, Santana LF, Hille B. Proximal clustering between BK and CaV1.3 channels promotes functional coupling and BK channel activation at low voltage. Elife. 2017 06 30; 6. PMID: 28665272.
      View in: PubMed
    9. Tajada S, Moreno CM, O'Dwyer S, Woods S, Sato D, Navedo MF, Santana LF. Distance constraints on activation of TRPV4 channels by AKAP150-bound PKCa in arterial myocytes. J Gen Physiol. 2017 Jun 05; 149(6):639-659. PMID: 28507079.
      View in: PubMed
    10. Li L, Li J, Drum BM, Chen Y, Yin H, Guo X, Luckey SW, Gilbert ML, McKnight GS, Scott JD, Santana LF, Liu Q. Loss of AKAP150 promotes pathological remodelling and heart failure propensity by disrupting calcium cycling and contractile reserve. Cardiovasc Res. 2017 02; 113(2):147-159. PMID: 27856611.
      View in: PubMed
    11. Ghosh D, Syed AU, Prada MP, Nystoriak MA, Santana LF, Nieves-Cintrón M, Navedo MF. Calcium Channels in Vascular Smooth Muscle. Adv Pharmacol. 2017; 78:49-87. PMID: 28212803.
      View in: PubMed
    12. Moreno CM, Dixon RE, Tajada S, Yuan C, Opitz-Araya X, Binder MD, Santana LF. Ca(2+) entry into neurons is facilitated by cooperative gating of clustered CaV1.3 channels. Elife. 2016 05 17; 5. PMID: 27187148.
      View in: PubMed
    13. Drum BM, Yuan C, Li L, Liu Q, Wordeman L, Santana LF. Oxidative stress decreases microtubule growth and stability in ventricular myocytes. J Mol Cell Cardiol. 2016 04; 93:32-43. PMID: 26902968.
      View in: PubMed
    14. Nieves-Cintrón M, Hirenallur-Shanthappa D, Nygren PJ, Hinke SA, Dell'Acqua ML, Langeberg LK, Navedo M, Santana LF, Scott JD. AKAP150 participates in calcineurin/NFAT activation during the down-regulation of voltage-gated K(+) currents in ventricular myocytes following myocardial infarction. Cell Signal. 2016 07; 28(7):733-40. PMID: 26724383.
      View in: PubMed
    15. Hehnly H, Canton D, Bucko P, Langeberg LK, Ogier L, Gelman I, Santana LF, Wordeman L, Scott JD. A mitotic kinase scaffold depleted in testicular seminomas impacts spindle orientation in germ line stem cells. Elife. 2015 Sep 25; 4:e09384. PMID: 26406118.
      View in: PubMed
    16. Dixon RE, Moreno CM, Yuan C, Opitz-Araya X, Binder MD, Navedo MF, Santana LF. Graded Ca²?/calmodulin-dependent coupling of voltage-gated CaV1.2 channels. Elife. 2015 Feb 25; 4. PMID: 25714924.
      View in: PubMed
    17. Drum BM, Santana LF. The long and winding road home: how junctin and triadin find their way to the junctional SR. J Mol Cell Cardiol. 2015 Apr; 81:15-7. PMID: 25655931.
      View in: PubMed
    18. Sonkusare SK, Dalsgaard T, Bonev AD, Hill-Eubanks DC, Kotlikoff MI, Scott JD, Santana LF, Nelson MT. AKAP150-dependent cooperative TRPV4 channel gating is central to endothelium-dependent vasodilation and is disrupted in hypertension. Sci Signal. 2014 Jul 08; 7(333):ra66. PMID: 25005230.
      View in: PubMed
    19. Mercado J, Baylie R, Navedo MF, Yuan C, Scott JD, Nelson MT, Brayden JE, Santana LF. Local control of TRPV4 channels by AKAP150-targeted PKC in arterial smooth muscle. J Gen Physiol. 2014 May; 143(5):559-75. PMID: 24778429.
      View in: PubMed
    20. Zhang C, Chen B, Guo A, Zhu Y, Miller JD, Gao S, Yuan C, Kutschke W, Zimmerman K, Weiss RM, Wehrens XH, Hong J, Johnson FL, Santana LF, Anderson ME, Song LS. Microtubule-mediated defects in junctophilin-2 trafficking contribute to myocyte transverse-tubule remodeling and Ca2+ handling dysfunction in heart failure. Circulation. 2014 Apr 29; 129(17):1742-50. PMID: 24519927.
      View in: PubMed
    21. Guan X, Mack DL, Moreno CM, Strande JL, Mathieu J, Shi Y, Markert CD, Wang Z, Liu G, Lawlor MW, Moorefield EC, Jones TN, Fugate JA, Furth ME, Murry CE, Ruohola-Baker H, Zhang Y, Santana LF, Childers MK. Dystrophin-deficient cardiomyocytes derived from human urine: new biologic reagents for drug discovery. Stem Cell Res. 2014 Mar; 12(2):467-80. PMID: 24434629.
      View in: PubMed
    22. Nystoriak MA, Nieves-Cintrón M, Nygren PJ, Hinke SA, Nichols CB, Chen CY, Puglisi JL, Izu LT, Bers DM, Dell'acqua ML, Scott JD, Santana LF, Navedo MF. AKAP150 contributes to enhanced vascular tone by facilitating large-conductance Ca2+-activated K+ channel remodeling in hyperglycemia and diabetes mellitus. Circ Res. 2014 Feb 14; 114(4):607-15. PMID: 24323672.
      View in: PubMed
    23. Drum BM, Dixon RE, Yuan C, Cheng EP, Santana LF. Cellular mechanisms of ventricular arrhythmias in a mouse model of Timothy syndrome (long QT syndrome 8). J Mol Cell Cardiol. 2014 Jan; 66:63-71. PMID: 24215710.
      View in: PubMed
    24. Tajada S, Cidad P, Colinas O, Santana LF, López-López JR, Pérez-García MT. Down-regulation of CaV1.2 channels during hypertension: how fewer CaV1.2 channels allow more Ca(2+) into hypertensive arterial smooth muscle. J Physiol. 2013 Dec 15; 591(24):6175-91. PMID: 24167226.
      View in: PubMed
    25. Gulia J, Navedo MF, Gui P, Chao JT, Mercado JL, Santana LF, Davis MJ. Regulation of L-type calcium channel sparklet activity by c-Src and PKC-a. Am J Physiol Cell Physiol. 2013 Sep; 305(5):C568-77. PMID: 23804206.
      View in: PubMed
    26. Dixon RE, Santana LF. A Ca2+- and PKC-driven regulatory network in airway smooth muscle. J Gen Physiol. 2013 Feb; 141(2):161-4. PMID: 23359280.
      View in: PubMed
    27. Navedo MF, Santana LF. CaV1.2 sparklets in heart and vascular smooth muscle. J Mol Cell Cardiol. 2013 May; 58:67-76. PMID: 23220157.
      View in: PubMed
    28. Santana LF, Mercado JL. Adding accessories for hypertension: a2d-1 subunits upregulate CaV1.2 channels in arterial myocytes in a model of genetic hypertension. Hypertension. 2012 Oct; 60(4):894-5. PMID: 22949527.
      View in: PubMed
    29. Hinke SA, Navedo MF, Ulman A, Whiting JL, Nygren PJ, Tian G, Jimenez-Caliani AJ, Langeberg LK, Cirulli V, Tengholm A, Dell'Acqua ML, Santana LF, Scott JD. Anchored phosphatases modulate glucose homeostasis. EMBO J. 2012 Oct 17; 31(20):3991-4004. PMID: 22940692.
      View in: PubMed
    30. Frock RL, Chen SC, Da DF, Frett E, Lau C, Brown C, Pak DN, Wang Y, Muchir A, Worman HJ, Santana LF, Ladiges WC, Rabinovitch PS, Kennedy BK. Cardiomyocyte-specific expression of lamin a improves cardiac function in Lmna-/- mice. PLoS One. 2012; 7(8):e42918. PMID: 22905185.
      View in: PubMed
    31. Dixon RE, Cheng EP, Mercado JL, Santana LF. L-type Ca2+ channel function during Timothy syndrome. Trends Cardiovasc Med. 2012 Apr; 22(3):72-6. PMID: 22999068.
      View in: PubMed
    32. Dixon RE, Yuan C, Cheng EP, Navedo MF, Santana LF. Ca2+ signaling amplification by oligomerization of L-type Cav1.2 channels. Proc Natl Acad Sci U S A. 2012 Jan 31; 109(5):1749-54. PMID: 22307641.
      View in: PubMed
    33. Flynn JM, Santana LF, Melov S. Single cell transcriptional profiling of adult mouse cardiomyocytes. J Vis Exp. 2011 Dec 28; (58):e3302. PMID: 22231655.
      View in: PubMed
    34. Means CK, Lygren B, Langeberg LK, Jain A, Dixon RE, Vega AL, Gold MG, Petrosyan S, Taylor SS, Murphy AN, Ha T, Santana LF, Tasken K, Scott JD. An entirely specific type I A-kinase anchoring protein that can sequester two molecules of protein kinase A at mitochondria. Proc Natl Acad Sci U S A. 2011 Nov 29; 108(48):E1227-35. PMID: 22084075.
      View in: PubMed
    35. Vega AL, Yuan C, Votaw VS, Santana LF. Dynamic changes in sarcoplasmic reticulum structure in ventricular myocytes. J Biomed Biotechnol. 2011; 2011:382586. PMID: 22131804.
      View in: PubMed
    36. Takeda Y, Nystoriak MA, Nieves-Cintrón M, Santana LF, Navedo MF. Relationship between Ca2+ sparklets and sarcoplasmic reticulum Ca2+ load and release in rat cerebral arterial smooth muscle. Am J Physiol Heart Circ Physiol. 2011 Dec; 301(6):H2285-94. PMID: 21984539.
      View in: PubMed
    37. Cheng EP, Yuan C, Navedo MF, Dixon RE, Nieves-Cintrón M, Scott JD, Santana LF. Restoration of normal L-type Ca2+ channel function during Timothy syndrome by ablation of an anchoring protein. Circ Res. 2011 Jul 22; 109(3):255-61. PMID: 21700933.
      View in: PubMed
    38. Dai DF, Chen T, Szeto H, Nieves-Cintrón M, Kutyavin V, Santana LF, Rabinovitch PS. Mitochondrial targeted antioxidant Peptide ameliorates hypertensive cardiomyopathy. J Am Coll Cardiol. 2011 Jun 28; 58(1):73-82. PMID: 21620606.
      View in: PubMed
    39. Dai DF, Johnson SC, Villarin JJ, Chin MT, Nieves-Cintrón M, Chen T, Marcinek DJ, Dorn GW, Kang YJ, Prolla TA, Santana LF, Rabinovitch PS. Mitochondrial oxidative stress mediates angiotensin II-induced cardiac hypertrophy and Galphaq overexpression-induced heart failure. Circ Res. 2011 Apr 01; 108(7):837-46. PMID: 21311045.
      View in: PubMed
    40. Lai Y, Oslund RC, Bollinger JG, Henderson WR, Santana LF, Altemeier WA, Gelb MH, Hallstrand TS. Eosinophil cysteinyl leukotriene synthesis mediated by exogenous secreted phospholipase A2 group X. J Biol Chem. 2010 Dec 31; 285(53):41491-500. PMID: 20974857.
      View in: PubMed
    41. Santana LF, Cheng EP, Lederer WJ. How does the shape of the cardiac action potential control calcium signaling and contraction in the heart? J Mol Cell Cardiol. 2010 Dec; 49(6):901-3. PMID: 20850450.
      View in: PubMed
    42. Santana LF, Navedo MF. Natural inequalities: why some L-type Ca2+ channels work harder than others. J Gen Physiol. 2010 Aug; 136(2):143-7. PMID: 20660657.
      View in: PubMed
    43. Nichols CB, Rossow CF, Navedo MF, Westenbroek RE, Catterall WA, Santana LF, McKnight GS. Sympathetic stimulation of adult cardiomyocytes requires association of AKAP5 with a subpopulation of L-type calcium channels. Circ Res. 2010 Sep 17; 107(6):747-56. PMID: 20671242.
      View in: PubMed
    44. Patrucco E, Albergine MS, Santana LF, Beavo JA. Phosphodiesterase 8A (PDE8A) regulates excitation-contraction coupling in ventricular myocytes. J Mol Cell Cardiol. 2010 Aug; 49(2):330-3. PMID: 20353794.
      View in: PubMed
    45. Scott JD, Santana LF. A-kinase anchoring proteins: getting to the heart of the matter. Circulation. 2010 Mar 16; 121(10):1264-71. PMID: 20231544.
      View in: PubMed
    46. Zhang J, Ren C, Chen L, Navedo MF, Antos LK, Kinsey SP, Iwamoto T, Philipson KD, Kotlikoff MI, Santana LF, Wier WG, Matteson DR, Blaustein MP. Knockout of Na+/Ca2+ exchanger in smooth muscle attenuates vasoconstriction and L-type Ca2+ channel current and lowers blood pressure. Am J Physiol Heart Circ Physiol. 2010 May; 298(5):H1472-83. PMID: 20173044.
      View in: PubMed
    47. Navedo MF, Cheng EP, Yuan C, Votaw S, Molkentin JD, Scott JD, Santana LF. Increased coupled gating of L-type Ca2+ channels during hypertension and Timothy syndrome. Circ Res. 2010 Mar 05; 106(4):748-56. PMID: 20110531.
      View in: PubMed
    48. Navedo MF, Takeda Y, Nieves-Cintrón M, Molkentin JD, Santana LF. Elevated Ca2+ sparklet activity during acute hyperglycemia and diabetes in cerebral arterial smooth muscle cells. Am J Physiol Cell Physiol. 2010 Feb; 298(2):C211-20. PMID: 19846755.
      View in: PubMed
    49. Rodgers BD, Interlichia JP, Garikipati DK, Mamidi R, Chandra M, Nelson OL, Murry CE, Santana LF. Myostatin represses physiological hypertrophy of the heart and excitation-contraction coupling. J Physiol. 2009 Oct 15; 587(Pt 20):4873-86. PMID: 19736304.
      View in: PubMed
    50. Santana LF, Navedo MF. Molecular and biophysical mechanisms of Ca2+ sparklets in smooth muscle. J Mol Cell Cardiol. 2009 Oct; 47(4):436-44. PMID: 19616004.
      View in: PubMed
    51. Dai DF, Santana LF, Vermulst M, Tomazela DM, Emond MJ, MacCoss MJ, Gollahon K, Martin GM, Loeb LA, Ladiges WC, Rabinovitch PS. Overexpression of catalase targeted to mitochondria attenuates murine cardiac aging. Circulation. 2009 Jun 02; 119(21):2789-97. PMID: 19451351.
      View in: PubMed
    52. Zhu WZ, Santana LF, Laflamme MA. Local control of excitation-contraction coupling in human embryonic stem cell-derived cardiomyocytes. PLoS One. 2009; 4(4):e5407. PMID: 19404384.
      View in: PubMed
    53. Rossow CF, Dilly KW, Yuan C, Nieves-Cintrón M, Cabarrus JL, Santana LF. NFATc3-dependent loss of I(to) gradient across the left ventricular wall during chronic beta adrenergic stimulation. J Mol Cell Cardiol. 2009 Feb; 46(2):249-56. PMID: 19027024.
      View in: PubMed
    54. Nieves-Cintrón M, Amberg GC, Navedo MF, Molkentin JD, Santana LF. The control of Ca2+ influx and NFATc3 signaling in arterial smooth muscle during hypertension. Proc Natl Acad Sci U S A. 2008 Oct 07; 105(40):15623-8. PMID: 18832165.
      View in: PubMed
    55. Santana LF. NFAT-dependent excitation-transcription coupling in heart. Circ Res. 2008 Sep 26; 103(7):681-3. PMID: 18818410.
      View in: PubMed
    56. Santana LF, Navedo MF, Amberg GC, Nieves-Cintrón M, Votaw VS, Ufret-Vincenty CA. Calcium sparklets in arterial smooth muscle. Clin Exp Pharmacol Physiol. 2008 Sep; 35(9):1121-6. PMID: 18215181.
      View in: PubMed
    57. Navedo MF, Nieves-Cintrón M, Amberg GC, Yuan C, Votaw VS, Lederer WJ, McKnight GS, Santana LF. AKAP150 is required for stuttering persistent Ca2+ sparklets and angiotensin II-induced hypertension. Circ Res. 2008 Feb 01; 102(2):e1-e11. PMID: 18174462.
      View in: PubMed
    58. Santana LF. SMAKing Ca2+ sparks in arterial myocytes. J Physiol. 2007 Oct 01; 584(Pt 1):1. PMID: 17717006.
      View in: PubMed
    59. Navedo MF, Amberg GC, Westenbroek RE, Sinnegger-Brauns MJ, Catterall WA, Striessnig J, Santana LF. Ca(v)1.3 channels produce persistent calcium sparklets, but Ca(v)1.2 channels are responsible for sparklets in mouse arterial smooth muscle. Am J Physiol Heart Circ Physiol. 2007 Sep; 293(3):H1359-70. PMID: 17526649.
      View in: PubMed
    60. Amberg GC, Navedo MF, Nieves-Cintrón M, Molkentin JD, Santana LF. Calcium sparklets regulate local and global calcium in murine arterial smooth muscle. J Physiol. 2007 Feb 15; 579(Pt 1):187-201. PMID: 17158168.
      View in: PubMed
    61. Nieves-Cintrón M, Amberg GC, Nichols CB, Molkentin JD, Santana LF. Activation of NFATc3 down-regulates the beta1 subunit of large conductance, calcium-activated K+ channels in arterial smooth muscle and contributes to hypertension. J Biol Chem. 2007 Feb 02; 282(5):3231-40. PMID: 17148444.
      View in: PubMed
    62. Stein AT, Ufret-Vincenty CA, Hua L, Santana LF, Gordon SE. Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane. J Gen Physiol. 2006 Nov; 128(5):509-22. PMID: 17074976.
      View in: PubMed
    63. Navedo MF, Amberg GC, Nieves M, Molkentin JD, Santana LF. Mechanisms underlying heterogeneous Ca2+ sparklet activity in arterial smooth muscle. J Gen Physiol. 2006 Jun; 127(6):611-22. PMID: 16702354.
      View in: PubMed
    64. Rossow CF, Dilly KW, Santana LF. Differential calcineurin/NFATc3 activity contributes to the Ito transmural gradient in the mouse heart. Circ Res. 2006 May 26; 98(10):1306-13. PMID: 16614306.
      View in: PubMed
    65. Amberg GC, Santana LF. Kv2 channels oppose myogenic constriction of rat cerebral arteries. Am J Physiol Cell Physiol. 2006 Aug; 291(2):C348-56. PMID: 16571867.
      View in: PubMed
    66. Amberg GC, Navedo MF, Santana LF. On the loose: uncaging Ca2+ -induced Ca2+ release in smooth muscle. J Gen Physiol. 2006 Mar; 127(3):221-3. PMID: 16505144.
      View in: PubMed
    67. Dilly KW, Rossow CF, Votaw VS, Meabon JS, Cabarrus JL, Santana LF. Mechanisms underlying variations in excitation-contraction coupling across the mouse left ventricular free wall. J Physiol. 2006 Apr 01; 572(Pt 1):227-41. PMID: 16423856.
      View in: PubMed
    68. Navedo MF, Amberg GC, Votaw VS, Santana LF. Constitutively active L-type Ca2+ channels. Proc Natl Acad Sci U S A. 2005 Aug 02; 102(31):11112-7. PMID: 16040810.
      View in: PubMed
    69. Santana LF, Núñez-Durán H, Dilly KW, Lederer WJ. Sodium current and arrhythmogenesis in heart failure. Heart Fail Clin. 2005 Jul; 1(2):193-205. PMID: 17386846.
      View in: PubMed
    70. Harris DM, Mills GD, Chen X, Kubo H, Berretta RM, Votaw VS, Santana LF, Houser SR. Alterations in early action potential repolarization causes localized failure of sarcoplasmic reticulum Ca2+ release. Circ Res. 2005 Mar 18; 96(5):543-50. PMID: 15705962.
      View in: PubMed
    71. Amberg GC, Rossow CF, Navedo MF, Santana LF. NFATc3 regulates Kv2.1 expression in arterial smooth muscle. J Biol Chem. 2004 Nov 05; 279(45):47326-34. PMID: 15322114.
      View in: PubMed
    72. Rossow CF, Minami E, Chase EG, Murry CE, Santana LF. NFATc3-induced reductions in voltage-gated K+ currents after myocardial infarction. Circ Res. 2004 May 28; 94(10):1340-50. PMID: 15087419.
      View in: PubMed
    73. Amberg GC, Santana LF. Downregulation of the BK channel beta1 subunit in genetic hypertension. Circ Res. 2003 Nov 14; 93(10):965-71. PMID: 14551242.
      View in: PubMed
    74. Amberg GC, Bonev AD, Rossow CF, Nelson MT, Santana LF. Modulation of the molecular composition of large conductance, Ca(2+) activated K(+) channels in vascular smooth muscle during hypertension. J Clin Invest. 2003 Sep; 112(5):717-24. PMID: 12952920.
      View in: PubMed
    75. Heppner TJ, Bonev AD, Santana LF, Nelson MT. Alkaline pH shifts Ca2+ sparks to Ca2+ waves in smooth muscle cells of pressurized cerebral arteries. Am J Physiol Heart Circ Physiol. 2002 Dec; 283(6):H2169-76. PMID: 12427589.
      View in: PubMed
    76. Santana LF, Chase EG, Votaw VS, Nelson MT, Greven R. Functional coupling of calcineurin and protein kinase A in mouse ventricular myocytes. J Physiol. 2002 Oct 01; 544(Pt 1):57-69. PMID: 12356880.
      View in: PubMed
    77. Santiago J, Guzmàn GR, Rojas LV, Marti R, Asmar-Rovira GA, Santana LF, McNamee M, Lasalde-Dominicci JA. Probing the effects of membrane cholesterol in the Torpedo californica acetylcholine receptor and the novel lipid-exposed mutation alpha C418W in Xenopus oocytes. J Biol Chem. 2001 Dec 07; 276(49):46523-32. PMID: 11567020.
      View in: PubMed
    78. Wellman GC, Santana LF, Bonev AD, Nelson MT. Role of phospholamban in the modulation of arterial Ca(2+) sparks and Ca(2+)-activated K(+) channels by cAMP. Am J Physiol Cell Physiol. 2001 Sep; 281(3):C1029-37. PMID: 11502581.
      View in: PubMed
    79. Ufret-Vincenty CA, Baro DJ, Santana LF. Differential contribution of sialic acid to the function of repolarizing K(+) currents in ventricular myocytes. Am J Physiol Cell Physiol. 2001 Aug; 281(2):C464-74. PMID: 11443045.
      View in: PubMed
    80. Ufret-Vincenty CA, Baro DJ, Lederer WJ, Rockman HA, Quinones LE, Santana LF. Role of sodium channel deglycosylation in the genesis of cardiac arrhythmias in heart failure. J Biol Chem. 2001 Jul 27; 276(30):28197-203. PMID: 11369778.
      View in: PubMed
    81. Esposito G, Santana LF, Dilly K, Cruz JD, Mao L, Lederer WJ, Rockman HA. Cellular and functional defects in a mouse model of heart failure. Am J Physiol Heart Circ Physiol. 2000 Dec; 279(6):H3101-12. PMID: 11087268.
      View in: PubMed
    82. Wessely R, Klingel K, Santana LF, Dalton N, Hongo M, Jonathan Lederer W, Kandolf R, Knowlton KU. Transgenic expression of replication-restricted enteroviral genomes in heart muscle induces defective excitation-contraction coupling and dilated cardiomyopathy. J Clin Invest. 1998 Oct 01; 102(7):1444-53. PMID: 9769337.
      View in: PubMed
    83. Santana LF, Gómez AM, Lederer WJ. Ca2+ flux through promiscuous cardiac Na+ channels: slip-mode conductance. Science. 1998 Feb 13; 279(5353):1027-33. PMID: 9461434.
      View in: PubMed
    84. Santana LF, Kranias EG, Lederer WJ. Calcium sparks and excitation-contraction coupling in phospholamban-deficient mouse ventricular myocytes. J Physiol. 1997 Aug 15; 503 ( Pt 1):21-9. PMID: 9288671.
      View in: PubMed
    85. Gómez AM, Valdivia HH, Cheng H, Lederer MR, Santana LF, Cannell MB, McCune SA, Altschuld RA, Lederer WJ. Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure. Science. 1997 May 02; 276(5313):800-6. PMID: 9115206.
      View in: PubMed
    86. Santana LF, Gómez AM, Kranias EG, Lederer WJ. Amount of calcium in the sarcoplasmic reticulum: influence on excitation-contraction coupling in heart muscle. Heart Vessels. 1997; Suppl 12:44-9. PMID: 9476542.
      View in: PubMed
    87. Klein MG, Cheng H, Santana LF, Jiang YH, Lederer WJ, Schneider MF. Two mechanisms of quantized calcium release in skeletal muscle. Nature. 1996 Feb 01; 379(6564):455-8. PMID: 8559251.
      View in: PubMed
    88. Santana LF, Cheng H, Gómez AM, Cannell MB, Lederer WJ. Relation between the sarcolemmal Ca2+ current and Ca2+ sparks and local control theories for cardiac excitation-contraction coupling. Circ Res. 1996 Jan; 78(1):166-71. PMID: 8603501.
      View in: PubMed
    89. Nelson MT, Cheng H, Rubart M, Santana LF, Bonev AD, Knot HJ, Lederer WJ. Relaxation of arterial smooth muscle by calcium sparks. Science. 1995 Oct 27; 270(5236):633-7. PMID: 7570021.
      View in: PubMed