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α1C S1928 Phosphorylation of CaV1.2 Channel Controls Vascular Reactivity and Blood Pressure. J Am Heart Assoc. 2024 Oct 15; 13(20):e035375.
Flores-Tamez VA, Martín-Aragón Baudel M, Hong J, Taylor JL, Ren L, Le T, Syed AU, Moustafa Y, Singhrao N, Lemus-Martinez WR, Reddy GR, Ramer V, Man KNM, Bartels P, Chen-Izu Y, Chen CY, Simo S, Dickson EJ, Morotti S, Grandi E, Santana LF, Hell JW, Horne MC, Nieves-Cintrón M, Navedo MF. PMID: 39377203.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Advances in induced pluripotent stem cell-derived cardiac myocytes: technological breakthroughs, key discoveries and new applications. J Physiol. 2024 Aug; 602(16):3871-3892.
Clancy CE, Santana LF. PMID: 39032073; PMCID: PMC11326976.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Fueling the heartbeat: Dynamic regulation of intracellular ATP during excitation-contraction coupling in ventricular myocytes. Proc Natl Acad Sci U S A. 2024 Jun 18; 121(25):e2318535121.
Rhana P, Matsumoto C, Fong Z, Costa AD, Del Villar SG, Dixon RE, Santana LF. PMID: 38865270; PMCID: PMC11194497.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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The life cycle of a capillary: Mechanisms of angiogenesis and rarefaction in microvascular physiology and pathologies. Vascul Pharmacol. 2024 Sep; 156:107393.
Manning D, Rivera EJ, Santana LF. PMID: 38857638.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
-
Uric acid and acute kidney injury in high-risk patients for developing acute kidney injury undergoing cardiac surgery: A prospective multicenter study. Rev Esp Anestesiol Reanim (Engl Ed). 2024 Aug-Sep; 71(7):514-521.
Nagore D, Candela A, Bürge M, Tamayo E, Murie-Fernández M, Vives M, Monedero P, Álvarez J, Mendez E, Pasqualetto A, Mon T, Pita R, Varela MA, Esteva C, Pereira MA, Sanchez J, Rodriguez MA, Garcia A, Carmona P, López M, Pajares A, Vicente R, Aparicio R, Gragera I, Calderón E, Marcos JM, Gómez L, Rodríguez JM, Matilla A, Medina A, Hernández A, Morales L, Santana L, Garcia E, Montesinos S, Muñoz P, Bravo B, Blanco V, en nombre del Grupo Español de Investigación en Cirugía Cardiaca Perioperatoria. PMID: 38704092.
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Translation:
Humans
-
Sorbs2 Modulation of BK Channels in Arterial Myocytes: Implications for Diabetes. Circ Res. 2024 Mar 29; 134(7):872-874.
Santana LF, Navedo MF. PMID: 38547252; PMCID: PMC10987049.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Juggling potassium: A diverse set of K+ channels tune excitability of brain's capillary pericytes. Biophys J. 2024 Jul 16; 123(14):1910-1911.
Fong Z, Santana LF. PMID: 38549373; PMCID: PMC11309975.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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SanPy: Software for the analysis and visualization of whole-cell current-clamp recordings. Biophys J. 2024 Apr 02; 123(7):759-769.
Guarina L, Le JT, Griffith TN, Santana LF, Cudmore RH. PMID: 38419330; PMCID: PMC10995421.
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PubMed Mentions: Fields:
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A computational model predicts sex-specific responses to calcium channel blockers in mammalian mesenteric vascular smooth muscle. Elife. 2024 Feb 09; 12.
Hernandez-Hernandez G, O'Dwyer SC, Yang PC, Matsumoto C, Tieu M, Fong Z, Lewis TJ, Santana LF, Clancy CE. PMID: 38335126; PMCID: PMC10942543.
View in:
PubMed Mentions:
2 Fields:
Translation:
Animals
-
A computational model predicts sex-specific responses to calcium channel blockers in mammalian mesenteric vascular smooth muscle. bioRxiv. 2024 Jan 06.
Hernandez-Hernandez G, O'Dwyer SC, Matsumoto C, Tieu M, Fong Z, Yang PC, Lewis TJ, Fernando Santana L, Clancy CE. PMID: 37425682; PMCID: PMC10327109.
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PubMed Mentions:
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Toward Digital Twin Technology for Precision Pharmacology. JACC Clin Electrophysiol. 2024 Feb; 10(2):359-364.
Yang PC, Jeng MT, Yarov-Yarovoy V, Santana LF, Vorobyov I, Clancy CE. PMID: 38069976.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Interstitial cells of Cajal - pacemakers of the gastrointestinal tract. J Physiol. 2023 Nov 23.
Sanders KM, Santana LF, Baker SA. PMID: 37997170.
View in:
PubMed Mentions:
5 Fields:
-
SanPy: A whole-cell electrophysiology analysis pipeline. bioRxiv. 2023 Sep 15.
Guarina L, Le JT, Griffith TN, Santana LF, Cudmore RH. PMID: 37214972; PMCID: PMC10197560.
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PubMed Mentions:
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A multiscale predictive digital twin for neurocardiac modulation. J Physiol. 2023 09; 601(17):3789-3812.
Yang PC, Rose A, DeMarco KR, Dawson JRD, Han Y, Jeng MT, Harvey RD, Santana LF, Ripplinger CM, Vorobyov I, Lewis TJ, Clancy CE. PMID: 37528537; PMCID: PMC10528740.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
The formation of KV2.1 macro-clusters is required for sex-specific differences in L-type CaV1.2 clustering and function in arterial myocytes. Res Sq. 2023 Jul 19.
Matsumoto C, O'Dwyer SC, Manning D, Hernandez-Hernandez G, Rhana P, Fong Z, Sato D, Clancy CE, Vierra NC, Trimmer JS, Santana LF. PMID: 37502980; PMCID: PMC10371172.
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PubMed Mentions:
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The formation of K V 2.1 macro-clusters is required for sex-specific differences in L-type Ca V 1.2 clustering and function in arterial myocytes. bioRxiv. 2023 Jun 29.
Matsumoto C, O'Dwyer SC, Manning D, Hernandez-Hernandez G, Rhana P, Fong Z, Sato D, Clancy CE, Vierra NC, Trimmer JS, Santana LF. PMID: 37425816; PMCID: PMC10327069.
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PubMed Mentions:
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Remodeled connexin 43 hemichannels alter cardiac excitability and promote arrhythmias. J Gen Physiol. 2023 07 03; 155(7).
Lillo MA, Muñoz M, Rhana P, Gaul-Muller K, Quan J, Shirokova N, Xie LH, Santana LF, Fraidenraich D, Contreras JE. PMID: 37191672; PMCID: PMC10192603.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
-
Blockade of Kv7 channels reverses the inhibitory effects of exchange protein directly activated by cAMP activation on purinergic contractions of the murine detrusor. Basic Clin Pharmacol Toxicol. 2023 Jul; 133(1):29-42.
Fong Z, Lall A, Mullins ND, Santana LF, Hollywood MA, Thornbury KD, Sergeant GP. PMID: 37125918.
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PubMed Mentions:
1 Fields:
Translation:
Animals
-
Regulating voltage-gated ion channels with nanobodies. Nat Commun. 2022 Dec 09; 13(1):7557.
Manning D, Santana LF. PMID: 36494383; PMCID: PMC9734093.
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PubMed Mentions: Fields:
-
Adenylyl cyclase isoform 1 contributes to sinoatrial node automaticity via functional microdomains. JCI Insight. 2022 11 22; 7(22).
Ren L, Thai PN, Gopireddy RR, Timofeyev V, Ledford HA, Woltz RL, Park S, Puglisi JL, Moreno CM, Santana LF, Conti AC, Kotlikoff MI, Xiang YK, Yarov-Yarovoy V, Zaccolo M, Zhang XD, Yamoah EN, Navedo MF, Chiamvimonvat N. PMID: 36509290; PMCID: PMC9746826.
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PubMed Mentions:
4 Fields:
Translation:
Animals
-
The Inferior Sinoatrial Node Suffers the Most During Heart Failure. JACC Clin Electrophysiol. 2022 11; 8(11):1354-1356.
Grainger N, Santana LF. PMID: 36424001; PMCID: PMC10031657.
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PubMed Mentions:
1 Fields:
Translation:
Humans
-
The Central Brain of the Heart: The Sinoatrial Node. JACC Clin Electrophysiol. 2022 10; 8(10):1216-1218.
Grainger N, Santana LF. PMID: 36265996; PMCID: PMC10031656.
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PubMed Mentions:
2 Fields:
Translation:
Humans
-
Piezo1 Tunes Blood Flow in the Central Nervous System. Circ Res. 2022 05 13; 130(10):1547-1549.
Cudmore RH, Santana LF. PMID: 35549371; PMCID: PMC9180419.
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PubMed Mentions:
2 Fields:
Translation:
Cells
-
Biological noise is a key determinant of the reproducibility and adaptability of cardiac pacemaking and EC coupling. J Gen Physiol. 2022 09 05; 154(9).
Guarina L, Moghbel AN, Pourhosseinzadeh MS, Cudmore RH, Sato D, Clancy CE, Santana LF. PMID: 35482009; PMCID: PMC9059386.
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PubMed Mentions:
12 Fields:
Translation:
Cells
-
The physiological sensor channels TRP and piezo: Nobel Prize in Physiology or Medicine 2021. Physiol Rev. 2022 04 01; 102(2):1153-1158.
Earley S, Santana LF, Lederer WJ. PMID: 35129367; PMCID: PMC8917909.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Mechanisms and physiological implications of cooperative gating of clustered ion channels. Physiol Rev. 2022 07 01; 102(3):1159-1210.
Dixon RE, Navedo MF, Binder MD, Santana LF. PMID: 34927454; PMCID: PMC8934683.
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PubMed Mentions:
31 Fields:
Translation:
HumansCells
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Regulation of neuronal excitation-transcription coupling by Kv2.1-induced clustering of somatic L-type Ca2+ channels at ER-PM junctions. Proc Natl Acad Sci U S A. 2021 11 16; 118(46).
Vierra NC, O'Dwyer SC, Matsumoto C, Santana LF, Trimmer JS. PMID: 34750263; PMCID: PMC8609631.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Genetically engineered mice for combinatorial cardiovascular optobiology. Elife. 2021 10 29; 10.
Lee FK, Lee JC, Shui B, Reining S, Jibilian M, Small DM, Jones JS, Allan-Rahill NH, Lamont MR, Rizzo MA, Tajada S, Navedo MF, Santana LF, Nishimura N, Kotlikoff MI. PMID: 34711305; PMCID: PMC8555989.
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PubMed Mentions:
7 Fields:
Translation:
Animals
-
IP3R-driven increases in mitochondrial Ca2+ promote neuronal death in NPC disease. Proc Natl Acad Sci U S A. 2021 10 05; 118(40).
Tiscione SA, Casas M, Horvath JD, Lam V, Hino K, Ory DS, Santana LF, Simó S, Dixon RE, Dickson EJ. PMID: 34580197; PMCID: PMC8501836.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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The Organization of the Sinoatrial Node Microvasculature Varies Regionally to Match Local Myocyte Excitability. Function (Oxf). 2021; 2(4):zqab031.
Grainger N, Guarina L, Cudmore RH, Santana LF. PMID: 34250490; PMCID: PMC8259512.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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AKAP5 complex facilitates purinergic modulation of vascular L-type Ca2+ channel CaV1.2. Nat Commun. 2020 10 20; 11(1):5303.
Prada MP, Syed AU, Reddy GR, Martín-Aragón Baudel M, Flores-Tamez VA, Sasse KC, Ward SM, Sirish P, Chiamvimonvat N, Bartels P, Dickson EJ, Hell JW, Scott JD, Santana LF, Xiang YK, Navedo MF, Nieves-Cintrón M. PMID: 33082339; PMCID: PMC7575592.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
-
Evolving Discovery of the Origin of the Heartbeat: A New Perspective on Sinus Rhythm. JACC Clin Electrophysiol. 2020 08; 6(8):932-934.
Clancy CE, Santana LF. PMID: 32819527.
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PubMed Mentions:
15 Fields:
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Maladaptive response of arterial myocytes to chronic exposure to Ca2+ channel blockers. Proc Natl Acad Sci U S A. 2020 08 04; 117(31):18151-18153.
O'Dwyer SC, Navedo MF, Santana LF. PMID: 32680960; PMCID: PMC7414083.
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PubMed Mentions: Fields:
Translation:
Humans
-
View in:
PubMed Mentions: Fields:
Translation:
Cells
-
Metabolic-electrical control of coronary blood flow. Proc Natl Acad Sci U S A. 2020 04 14; 117(15):8231-8233.
Grainger N, Santana LF. PMID: 32238556; PMCID: PMC7165467.
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PubMed Mentions:
3 Fields:
-
Kv2.1 channels play opposing roles in regulating membrane potential, Ca2+ channel function, and myogenic tone in arterial smooth muscle. Proc Natl Acad Sci U S A. 2020 02 18; 117(7):3858-3866.
O'Dwyer SC, Palacio S, Matsumoto C, Guarina L, Klug NR, Tajada S, Rosati B, McKinnon D, Trimmer JS, Santana LF. PMID: 32015129; PMCID: PMC7035623.
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PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
-
Junctional sarcoplasmic reticulum motility in adult mouse ventricular myocytes. Am J Physiol Cell Physiol. 2020 03 01; 318(3):C598-C604.
Drum BM, Yuan C, de la Mata A, Grainger N, Santana LF. PMID: 31967858; PMCID: PMC7099518.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
-
Kv2.1 mediates spatial and functional coupling of L-type calcium channels and ryanodine receptors in mammalian neurons. Elife. 2019 10 30; 8.
Vierra NC, Kirmiz M, van der List D, Santana LF, Trimmer JS. PMID: 31663850; PMCID: PMC6839919.
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PubMed Mentions:
48 Fields:
Translation:
HumansAnimalsCells
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Disease-associated mutations in Niemann-Pick type C1 alter ER calcium signaling and neuronal plasticity. J Cell Biol. 2019 12 02; 218(12):4141-4156.
Tiscione SA, Vivas O, Ginsburg KS, Bers DM, Ory DS, Santana LF, Dixon RE, Dickson EJ. PMID: 31601621; PMCID: PMC6891088.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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A toolbox of nanobodies developed and validated for use as intrabodies and nanoscale immunolabels in mammalian brain neurons. Elife. 2019 09 30; 8.
Dong JX, Lee Y, Kirmiz M, Palacio S, Dumitras C, Moreno CM, Sando R, Santana LF, Südhof TC, Gong B, Murray KD, Trimmer JS. PMID: 31566565; PMCID: PMC6785268.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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A stochastic model of ion channel cluster formation in the plasma membrane. J Gen Physiol. 2019 09 02; 151(9):1116-1134.
Sato D, Hernández-Hernández G, Matsumoto C, Tajada S, Moreno CM, Dixon RE, O'Dwyer S, Navedo MF, Trimmer JS, Clancy CE, Binder MD, Santana LF. PMID: 31371391; PMCID: PMC6719406.
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PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Adenylyl cyclase 5-generated cAMP controls cerebral vascular reactivity during diabetic hyperglycemia. J Clin Invest. 2019 06 04; 129(8):3140-3152.
Syed AU, Reddy GR, Ghosh D, Prada MP, Nystoriak MA, Morotti S, Grandi E, Sirish P, Chiamvimonvat N, Hell JW, Santana LF, Xiang YK, Nieves-Cintrón M, Navedo MF. PMID: 31162142; PMCID: PMC6668679.
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PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
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A Gs-coupled purinergic receptor boosts Ca2+ influx and vascular contractility during diabetic hyperglycemia. Elife. 2019 03 01; 8.
Prada MP, Syed AU, Buonarati OR, Reddy GR, Nystoriak MA, Ghosh D, Simó S, Sato D, Sasse KC, Ward SM, Santana LF, Xiang YK, Hell JW, Nieves-Cintrón M, Navedo MF. PMID: 30821687; PMCID: PMC6397001.
View in:
PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
-
BIN1 Induces the Formation of T-Tubules and Adult-Like Ca2+ Release Units in Developing Cardiomyocytes. Stem Cells. 2019 01; 37(1):54-64.
De La Mata A, Tajada S, O'Dwyer S, Matsumoto C, Dixon RE, Hariharan N, Moreno CM, Santana LF. PMID: 30353632; PMCID: PMC6312737.
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PubMed Mentions:
29 Fields:
Translation:
HumansCells
-
Single nucleotide polymorphisms alter kinase anchoring and the subcellular targeting of A-kinase anchoring proteins. Proc Natl Acad Sci U S A. 2018 12 04; 115(49):E11465-E11474.
Smith FD, Omar MH, Nygren PJ, Soughayer J, Hoshi N, Lau HT, Snyder CG, Branon TC, Ghosh D, Langeberg LK, Ting AY, Santana LF, Ong SE, Navedo MF, Scott JD. PMID: 30455320; PMCID: PMC6298107.
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PubMed Mentions:
26 Fields:
Translation:
HumansCells
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Dynamic L-type CaV1.2 channel trafficking facilitates CaV1.2 clustering and cooperative gating. Biochim Biophys Acta Mol Cell Res. 2018 09; 1865(9):1341-1355.
Ghosh D, Nieves-Cintrón M, Tajada S, Brust-Mascher I, Horne MC, Hell JW, Dixon RE, Santana LF, Navedo MF. PMID: 29959960; PMCID: PMC6407617.
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PubMed Mentions:
22 Fields:
Translation:
HumansCells
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A model for cooperative gating of L-type Ca2+ channels and its effects on cardiac alternans dynamics. PLoS Comput Biol. 2018 01; 14(1):e1005906.
Sato D, Dixon RE, Santana LF, Navedo MF. PMID: 29338006; PMCID: PMC5786340.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Impaired BKCa channel function in native vascular smooth muscle from humans with type 2 diabetes. Sci Rep. 2017 10 25; 7(1):14058.
Nieves-Cintrón M, Syed AU, Buonarati OR, Rigor RR, Nystoriak MA, Ghosh D, Sasse KC, Ward SM, Santana LF, Hell JW, Navedo MF. PMID: 29070899; PMCID: PMC5656614.
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PubMed Mentions:
23 Fields:
Translation:
HumansCells
-
A New Mutation in FIG4 Causes a Severe Form of CMT4J Involving TRPV4 in the Pathogenic Cascade. J Neuropathol Exp Neurol. 2017 Sep 01; 76(9):789-799.
Gentil BJ, O'Ferrall E, Chalk C, Santana LF, Durham HD, Massie R. PMID: 28859335; PMCID: PMC6251583.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Proximal clustering between BK and CaV1.3 channels promotes functional coupling and BK channel activation at low voltage. Elife. 2017 06 30; 6.
Vivas O, Moreno CM, Santana LF, Hille B. PMID: 28665272; PMCID: PMC5503510.
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PubMed Mentions:
36 Fields:
Translation:
AnimalsCells
-
Distance constraints on activation of TRPV4 channels by AKAP150-bound PKCα in arterial myocytes. J Gen Physiol. 2017 Jun 05; 149(6):639-659.
Tajada S, Moreno CM, O'Dwyer S, Woods S, Sato D, Navedo MF, Santana LF. PMID: 28507079; PMCID: PMC5460949.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
-
Loss of AKAP150 promotes pathological remodelling and heart failure propensity by disrupting calcium cycling and contractile reserve. Cardiovasc Res. 2017 02; 113(2):147-159.
Li L, Li J, Drum BM, Chen Y, Yin H, Guo X, Luckey SW, Gilbert ML, McKnight GS, Scott JD, Santana LF, Liu Q. PMID: 27856611; PMCID: PMC5340143.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
-
Calcium Channels in Vascular Smooth Muscle. Adv Pharmacol. 2017; 78:49-87.
Ghosh D, Syed AU, Prada MP, Nystoriak MA, Santana LF, Nieves-Cintrón M, Navedo MF. PMID: 28212803; PMCID: PMC5439506.
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PubMed Mentions:
44 Fields:
Translation:
HumansAnimalsCells
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Ca(2+) entry into neurons is facilitated by cooperative gating of clustered CaV1.3 channels. Elife. 2016 05 17; 5.
Moreno CM, Dixon RE, Tajada S, Yuan C, Opitz-Araya X, Binder MD, Santana LF. PMID: 27187148; PMCID: PMC4869912.
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PubMed Mentions:
44 Fields:
Translation:
AnimalsCells
-
Oxidative stress decreases microtubule growth and stability in ventricular myocytes. J Mol Cell Cardiol. 2016 04; 93:32-43.
Drum BM, Yuan C, Li L, Liu Q, Wordeman L, Santana LF. PMID: 26902968; PMCID: PMC4902331.
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PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
-
AKAP150 participates in calcineurin/NFAT activation during the down-regulation of voltage-gated K(+) currents in ventricular myocytes following myocardial infarction. Cell Signal. 2016 07; 28(7):733-40.
Nieves-Cintrón M, Hirenallur-Shanthappa D, Nygren PJ, Hinke SA, Dell'Acqua ML, Langeberg LK, Navedo M, Santana LF, Scott JD. PMID: 26724383; PMCID: PMC4902329.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
-
A mitotic kinase scaffold depleted in testicular seminomas impacts spindle orientation in germ line stem cells. Elife. 2015 Sep 25; 4:e09384.
Hehnly H, Canton D, Bucko P, Langeberg LK, Ogier L, Gelman I, Santana LF, Wordeman L, Scott JD. PMID: 26406118; PMCID: PMC4612572.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Graded Ca²⁺/calmodulin-dependent coupling of voltage-gated CaV1.2 channels. Elife. 2015 Feb 25; 4.
Dixon RE, Moreno CM, Yuan C, Opitz-Araya X, Binder MD, Navedo MF, Santana LF. PMID: 25714924; PMCID: PMC4360655.
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PubMed Mentions:
72 Fields:
Translation:
HumansAnimalsCells
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The long and winding road home: how junctin and triadin find their way to the junctional SR. J Mol Cell Cardiol. 2015 Apr; 81:15-7.
Drum BM, Santana LF. PMID: 25655931; PMCID: PMC4652856.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
-
AKAP150-dependent cooperative TRPV4 channel gating is central to endothelium-dependent vasodilation and is disrupted in hypertension. Sci Signal. 2014 Jul 08; 7(333):ra66.
Sonkusare SK, Dalsgaard T, Bonev AD, Hill-Eubanks DC, Kotlikoff MI, Scott JD, Santana LF, Nelson MT. PMID: 25005230; PMCID: PMC4403000.
View in:
PubMed Mentions:
97 Fields:
Translation:
AnimalsCells
-
Local control of TRPV4 channels by AKAP150-targeted PKC in arterial smooth muscle. J Gen Physiol. 2014 May; 143(5):559-75.
Mercado J, Baylie R, Navedo MF, Yuan C, Scott JD, Nelson MT, Brayden JE, Santana LF. PMID: 24778429; PMCID: PMC4003184.
View in:
PubMed Mentions:
61 Fields:
Translation:
HumansAnimalsCells
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Evaluation of clinical safety and anthelmintic efficacy of aurixazole administed orally at 24 mg/kg in cattle. Res Vet Sci. 2014 Jun; 96(3):493-500.
Sakamoto CA, Lopes WD, Buzzulini C, Cruz BC, Felippelli G, Teixeira WF, Silva HM, Santana LF, Soares VE, Henrique CH, de Oliveira GP, da Costa AJ. PMID: 24656344.
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PubMed Mentions: Fields:
Translation:
Animals
-
Microtubule-mediated defects in junctophilin-2 trafficking contribute to myocyte transverse-tubule remodeling and Ca2+ handling dysfunction in heart failure. Circulation. 2014 Apr 29; 129(17):1742-50.
Zhang C, Chen B, Guo A, Zhu Y, Miller JD, Gao S, Yuan C, Kutschke W, Zimmerman K, Weiss RM, Wehrens XH, Hong J, Johnson FL, Santana LF, Anderson ME, Song LS. PMID: 24519927; PMCID: PMC4006305.
View in:
PubMed Mentions:
94 Fields:
Translation:
HumansAnimalsCells
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Dystrophin-deficient cardiomyocytes derived from human urine: new biologic reagents for drug discovery. Stem Cell Res. 2014 Mar; 12(2):467-80.
Guan X, Mack DL, Moreno CM, Strande JL, Mathieu J, Shi Y, Markert CD, Wang Z, Liu G, Lawlor MW, Moorefield EC, Jones TN, Fugate JA, Furth ME, Murry CE, Ruohola-Baker H, Zhang Y, Santana LF, Childers MK. PMID: 24434629; PMCID: PMC3966181.
View in:
PubMed Mentions:
77 Fields:
Translation:
HumansAnimalsCells
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AKAP150 contributes to enhanced vascular tone by facilitating large-conductance Ca2+-activated K+ channel remodeling in hyperglycemia and diabetes mellitus. Circ Res. 2014 Feb 14; 114(4):607-15.
Nystoriak MA, Nieves-Cintrón M, Nygren PJ, Hinke SA, Nichols CB, Chen CY, Puglisi JL, Izu LT, Bers DM, Dell'acqua ML, Scott JD, Santana LF, Navedo MF. PMID: 24323672; PMCID: PMC3954117.
View in:
PubMed Mentions:
59 Fields:
Translation:
AnimalsCells
-
Cellular mechanisms of ventricular arrhythmias in a mouse model of Timothy syndrome (long QT syndrome 8). J Mol Cell Cardiol. 2014 Jan; 66:63-71.
Drum BM, Dixon RE, Yuan C, Cheng EP, Santana LF. PMID: 24215710; PMCID: PMC3903114.
View in:
PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
-
Down-regulation of CaV1.2 channels during hypertension: how fewer CaV1.2 channels allow more Ca(2+) into hypertensive arterial smooth muscle. J Physiol. 2013 Dec 15; 591(24):6175-91.
Tajada S, Cidad P, Colinas O, Santana LF, López-López JR, Pérez-García MT. PMID: 24167226; PMCID: PMC3892470.
View in:
PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
-
Anthelmintic efficacy of an oral formulation of Aurixazol against gastrointestinal nematodes of naturally and experimentally infected sheep. Vet Parasitol. 2013 Dec 06; 198(3-4):336-44.
Sakamoto CA, Lopes WD, Buzzulini C, Cruz BC, Felippelli G, de Lima RC, dos Santos TR, Santana LF, de Mendonça RP, Soares VE, Henrique CH, da Costa AJ. PMID: 24138723.
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PubMed Mentions: Fields:
Translation:
Animals
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Regulation of L-type calcium channel sparklet activity by c-Src and PKC-α. Am J Physiol Cell Physiol. 2013 Sep; 305(5):C568-77.
Gulia J, Navedo MF, Gui P, Chao JT, Mercado JL, Santana LF, Davis MJ. PMID: 23804206; PMCID: PMC3761150.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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A Ca2+- and PKC-driven regulatory network in airway smooth muscle. J Gen Physiol. 2013 Feb; 141(2):161-4.
Dixon RE, Santana LF. PMID: 23359280; PMCID: PMC3557310.
View in:
PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
-
CaV1.2 sparklets in heart and vascular smooth muscle. J Mol Cell Cardiol. 2013 May; 58:67-76.
Navedo MF, Santana LF. PMID: 23220157; PMCID: PMC3678956.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansCells
-
Adding accessories for hypertension: α2δ-1 subunits upregulate CaV1.2 channels in arterial myocytes in a model of genetic hypertension. Hypertension. 2012 Oct; 60(4):894-5.
Santana LF, Mercado JL. PMID: 22949527; PMCID: PMC3686101.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
-
Anchored phosphatases modulate glucose homeostasis. EMBO J. 2012 Oct 17; 31(20):3991-4004.
Hinke SA, Navedo MF, Ulman A, Whiting JL, Nygren PJ, Tian G, Jimenez-Caliani AJ, Langeberg LK, Cirulli V, Tengholm A, Dell'Acqua ML, Santana LF, Scott JD. PMID: 22940692; PMCID: PMC3474922.
View in:
PubMed Mentions:
44 Fields:
Translation:
AnimalsCells
-
Cardiomyocyte-specific expression of lamin a improves cardiac function in Lmna-/- mice. PLoS One. 2012; 7(8):e42918.
Frock RL, Chen SC, Da DF, Frett E, Lau C, Brown C, Pak DN, Wang Y, Muchir A, Worman HJ, Santana LF, Ladiges WC, Rabinovitch PS, Kennedy BK. PMID: 22905185; PMCID: PMC3419749.
View in:
PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
-
L-type Ca2+ channel function during Timothy syndrome. Trends Cardiovasc Med. 2012 Apr; 22(3):72-6.
Dixon RE, Cheng EP, Mercado JL, Santana LF. PMID: 22999068; PMCID: PMC3640256.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Ca2+ signaling amplification by oligomerization of L-type Cav1.2 channels. Proc Natl Acad Sci U S A. 2012 Jan 31; 109(5):1749-54.
Dixon RE, Yuan C, Cheng EP, Navedo MF, Santana LF. PMID: 22307641; PMCID: PMC3277143.
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PubMed Mentions:
77 Fields:
Translation:
AnimalsCells
-
Single cell transcriptional profiling of adult mouse cardiomyocytes. J Vis Exp. 2011 Dec 28; (58):e3302.
Flynn JM, Santana LF, Melov S. PMID: 22231655; PMCID: PMC3369660.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
-
An entirely specific type I A-kinase anchoring protein that can sequester two molecules of protein kinase A at mitochondria. Proc Natl Acad Sci U S A. 2011 Nov 29; 108(48):E1227-35.
Means CK, Lygren B, Langeberg LK, Jain A, Dixon RE, Vega AL, Gold MG, Petrosyan S, Taylor SS, Murphy AN, Ha T, Santana LF, Tasken K, Scott JD. PMID: 22084075; PMCID: PMC3228425.
View in:
PubMed Mentions:
73 Fields:
Translation:
HumansAnimalsCells
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Dynamic changes in sarcoplasmic reticulum structure in ventricular myocytes. J Biomed Biotechnol. 2011; 2011:382586.
Vega AL, Yuan C, Votaw VS, Santana LF. PMID: 22131804; PMCID: PMC3206393.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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Relationship between Ca2+ sparklets and sarcoplasmic reticulum Ca2+ load and release in rat cerebral arterial smooth muscle. Am J Physiol Heart Circ Physiol. 2011 Dec; 301(6):H2285-94.
Takeda Y, Nystoriak MA, Nieves-Cintrón M, Santana LF, Navedo MF. PMID: 21984539; PMCID: PMC3233819.
View in:
PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
-
Restoration of normal L-type Ca2+ channel function during Timothy syndrome by ablation of an anchoring protein. Circ Res. 2011 Jul 22; 109(3):255-61.
Cheng EP, Yuan C, Navedo MF, Dixon RE, Nieves-Cintrón M, Scott JD, Santana LF. PMID: 21700933; PMCID: PMC3151468.
View in:
PubMed Mentions:
68 Fields:
Translation:
AnimalsCells
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Mitochondrial targeted antioxidant Peptide ameliorates hypertensive cardiomyopathy. J Am Coll Cardiol. 2011 Jun 28; 58(1):73-82.
Dai DF, Chen T, Szeto H, Nieves-Cintrón M, Kutyavin V, Santana LF, Rabinovitch PS. PMID: 21620606; PMCID: PMC3742010.
View in:
PubMed Mentions:
175 Fields:
Translation:
AnimalsCells
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Mitochondrial oxidative stress mediates angiotensin II-induced cardiac hypertrophy and Galphaq overexpression-induced heart failure. Circ Res. 2011 Apr 01; 108(7):837-46.
Dai DF, Johnson SC, Villarin JJ, Chin MT, Nieves-Cintrón M, Chen T, Marcinek DJ, Dorn GW, Kang YJ, Prolla TA, Santana LF, Rabinovitch PS. PMID: 21311045; PMCID: PMC3785241.
View in:
PubMed Mentions:
249 Fields:
Translation:
AnimalsCells
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Eosinophil cysteinyl leukotriene synthesis mediated by exogenous secreted phospholipase A2 group X. J Biol Chem. 2010 Dec 31; 285(53):41491-500.
Lai Y, Oslund RC, Bollinger JG, Henderson WR, Santana LF, Altemeier WA, Gelb MH, Hallstrand TS. PMID: 20974857; PMCID: PMC3009875.
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PubMed Mentions:
22 Fields:
Translation:
HumansCells
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How does the shape of the cardiac action potential control calcium signaling and contraction in the heart? J Mol Cell Cardiol. 2010 Dec; 49(6):901-3.
Santana LF, Cheng EP, Lederer WJ. PMID: 20850450; PMCID: PMC3623268.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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Natural inequalities: why some L-type Ca2+ channels work harder than others. J Gen Physiol. 2010 Aug; 136(2):143-7.
Santana LF, Navedo MF. PMID: 20660657; PMCID: PMC2912067.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
-
Sympathetic stimulation of adult cardiomyocytes requires association of AKAP5 with a subpopulation of L-type calcium channels. Circ Res. 2010 Sep 17; 107(6):747-56.
Nichols CB, Rossow CF, Navedo MF, Westenbroek RE, Catterall WA, Santana LF, McKnight GS. PMID: 20671242; PMCID: PMC2981172.
View in:
PubMed Mentions:
95 Fields:
Translation:
AnimalsCells
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Phosphodiesterase 8A (PDE8A) regulates excitation-contraction coupling in ventricular myocytes. J Mol Cell Cardiol. 2010 Aug; 49(2):330-3.
Patrucco E, Albergine MS, Santana LF, Beavo JA. PMID: 20353794; PMCID: PMC2885478.
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PubMed Mentions:
43 Fields:
Translation:
AnimalsCells
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A-kinase anchoring proteins: getting to the heart of the matter. Circulation. 2010 Mar 16; 121(10):1264-71.
Scott JD, Santana LF. PMID: 20231544; PMCID: PMC3014256.
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PubMed Mentions:
34 Fields:
Translation:
HumansAnimalsCells
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Knockout of Na+/Ca2+ exchanger in smooth muscle attenuates vasoconstriction and L-type Ca2+ channel current and lowers blood pressure. Am J Physiol Heart Circ Physiol. 2010 May; 298(5):H1472-83.
Zhang J, Ren C, Chen L, Navedo MF, Antos LK, Kinsey SP, Iwamoto T, Philipson KD, Kotlikoff MI, Santana LF, Wier WG, Matteson DR, Blaustein MP. PMID: 20173044; PMCID: PMC2867439.
View in:
PubMed Mentions:
44 Fields:
Translation:
AnimalsCells
-
Increased coupled gating of L-type Ca2+ channels during hypertension and Timothy syndrome. Circ Res. 2010 Mar 05; 106(4):748-56.
Navedo MF, Cheng EP, Yuan C, Votaw S, Molkentin JD, Scott JD, Santana LF. PMID: 20110531; PMCID: PMC2834417.
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PubMed Mentions:
97 Fields:
Translation:
HumansAnimalsCells
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Elevated Ca2+ sparklet activity during acute hyperglycemia and diabetes in cerebral arterial smooth muscle cells. Am J Physiol Cell Physiol. 2010 Feb; 298(2):C211-20.
Navedo MF, Takeda Y, Nieves-Cintrón M, Molkentin JD, Santana LF. PMID: 19846755; PMCID: PMC2822492.
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PubMed Mentions:
60 Fields:
Translation:
AnimalsCells
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Myostatin represses physiological hypertrophy of the heart and excitation-contraction coupling. J Physiol. 2009 Oct 15; 587(Pt 20):4873-86.
Rodgers BD, Interlichia JP, Garikipati DK, Mamidi R, Chandra M, Nelson OL, Murry CE, Santana LF. PMID: 19736304; PMCID: PMC2770153.
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PubMed Mentions:
39 Fields:
Translation:
HumansAnimalsCells
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Molecular and biophysical mechanisms of Ca2+ sparklets in smooth muscle. J Mol Cell Cardiol. 2009 Oct; 47(4):436-44.
Santana LF, Navedo MF. PMID: 19616004; PMCID: PMC2739251.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
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Aspects of toxoplasma infection on the reproductive system of experimentally infected rams (ovis aries). J Parasitol Res. 2009; 2009.
Lopes WD, da Costa AJ, Santana LF, Dos Santos RS, Rossanese WM, Lopes WC, Costa GH, Sakamoto CA, Dos Santos TR. PMID: 20721328; PMCID: PMC2915749.
View in:
PubMed Mentions:
8
-
Overexpression of catalase targeted to mitochondria attenuates murine cardiac aging. Circulation. 2009 Jun 02; 119(21):2789-97.
Dai DF, Santana LF, Vermulst M, Tomazela DM, Emond MJ, MacCoss MJ, Gollahon K, Martin GM, Loeb LA, Ladiges WC, Rabinovitch PS. PMID: 19451351; PMCID: PMC2858759.
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PubMed Mentions:
264 Fields:
Translation:
AnimalsCells
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Local control of excitation-contraction coupling in human embryonic stem cell-derived cardiomyocytes. PLoS One. 2009; 4(4):e5407.
Zhu WZ, Santana LF, Laflamme MA. PMID: 19404384; PMCID: PMC2671137.
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PubMed Mentions:
40 Fields:
Translation:
HumansCells
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NFATc3-dependent loss of I(to) gradient across the left ventricular wall during chronic beta adrenergic stimulation. J Mol Cell Cardiol. 2009 Feb; 46(2):249-56.
Rossow CF, Dilly KW, Yuan C, Nieves-Cintrón M, Cabarrus JL, Santana LF. PMID: 19027024; PMCID: PMC2664558.
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PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
-
The control of Ca2+ influx and NFATc3 signaling in arterial smooth muscle during hypertension. Proc Natl Acad Sci U S A. 2008 Oct 07; 105(40):15623-8.
Nieves-Cintrón M, Amberg GC, Navedo MF, Molkentin JD, Santana LF. PMID: 18832165; PMCID: PMC2557027.
View in:
PubMed Mentions:
67 Fields:
Translation:
HumansAnimalsCells
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NFAT-dependent excitation-transcription coupling in heart. Circ Res. 2008 Sep 26; 103(7):681-3.
Santana LF. PMID: 18818410; PMCID: PMC2664551.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
-
Calcium sparklets in arterial smooth muscle. Clin Exp Pharmacol Physiol. 2008 Sep; 35(9):1121-6.
Santana LF, Navedo MF, Amberg GC, Nieves-Cintrón M, Votaw VS, Ufret-Vincenty CA. PMID: 18215181; PMCID: PMC5832963.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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AKAP150 is required for stuttering persistent Ca2+ sparklets and angiotensin II-induced hypertension. Circ Res. 2008 Feb 01; 102(2):e1-e11.
Navedo MF, Nieves-Cintrón M, Amberg GC, Yuan C, Votaw VS, Lederer WJ, McKnight GS, Santana LF. PMID: 18174462.
View in:
PubMed Mentions:
87 Fields:
Translation:
AnimalsCells
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SMAKing Ca2+ sparks in arterial myocytes. J Physiol. 2007 Oct 01; 584(Pt 1):1.
Santana LF. PMID: 17717006; PMCID: PMC2277070.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
-
Ca(v)1.3 channels produce persistent calcium sparklets, but Ca(v)1.2 channels are responsible for sparklets in mouse arterial smooth muscle. Am J Physiol Heart Circ Physiol. 2007 Sep; 293(3):H1359-70.
Navedo MF, Amberg GC, Westenbroek RE, Sinnegger-Brauns MJ, Catterall WA, Striessnig J, Santana LF. PMID: 17526649.
View in:
PubMed Mentions:
36 Fields:
Translation:
AnimalsCells
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Calcium sparklets regulate local and global calcium in murine arterial smooth muscle. J Physiol. 2007 Feb 15; 579(Pt 1):187-201.
Amberg GC, Navedo MF, Nieves-Cintrón M, Molkentin JD, Santana LF. PMID: 17158168; PMCID: PMC2075382.
View in:
PubMed Mentions:
52 Fields:
Translation:
AnimalsCells
-
Activation of NFATc3 down-regulates the beta1 subunit of large conductance, calcium-activated K+ channels in arterial smooth muscle and contributes to hypertension. J Biol Chem. 2007 Feb 02; 282(5):3231-40.
Nieves-Cintrón M, Amberg GC, Nichols CB, Molkentin JD, Santana LF. PMID: 17148444.
View in:
PubMed Mentions:
72 Fields:
Translation:
AnimalsCells
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Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane. J Gen Physiol. 2006 Nov; 128(5):509-22.
Stein AT, Ufret-Vincenty CA, Hua L, Santana LF, Gordon SE. PMID: 17074976; PMCID: PMC2151588.
View in:
PubMed Mentions:
188 Fields:
Translation:
HumansCells
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Mechanisms underlying heterogeneous Ca2+ sparklet activity in arterial smooth muscle. J Gen Physiol. 2006 Jun; 127(6):611-22.
Navedo MF, Amberg GC, Nieves M, Molkentin JD, Santana LF. PMID: 16702354; PMCID: PMC2151539.
View in:
PubMed Mentions:
80 Fields:
Translation:
AnimalsCells
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Differential calcineurin/NFATc3 activity contributes to the Ito transmural gradient in the mouse heart. Circ Res. 2006 May 26; 98(10):1306-13.
Rossow CF, Dilly KW, Santana LF. PMID: 16614306.
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PubMed Mentions:
35 Fields:
Translation:
AnimalsCells
-
Kv2 channels oppose myogenic constriction of rat cerebral arteries. Am J Physiol Cell Physiol. 2006 Aug; 291(2):C348-56.
Amberg GC, Santana LF. PMID: 16571867.
View in:
PubMed Mentions:
60 Fields:
Translation:
AnimalsCells
-
On the loose: uncaging Ca2+ -induced Ca2+ release in smooth muscle. J Gen Physiol. 2006 Mar; 127(3):221-3.
Amberg GC, Navedo MF, Santana LF. PMID: 16505144; PMCID: PMC2151499.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Mechanisms underlying variations in excitation-contraction coupling across the mouse left ventricular free wall. J Physiol. 2006 Apr 01; 572(Pt 1):227-41.
Dilly KW, Rossow CF, Votaw VS, Meabon JS, Cabarrus JL, Santana LF. PMID: 16423856; PMCID: PMC1779645.
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PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
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Constitutively active L-type Ca2+ channels. Proc Natl Acad Sci U S A. 2005 Aug 02; 102(31):11112-7.
Navedo MF, Amberg GC, Votaw VS, Santana LF. PMID: 16040810; PMCID: PMC1180225.
View in:
PubMed Mentions:
128 Fields:
Translation:
AnimalsCells
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Sodium current and arrhythmogenesis in heart failure. Heart Fail Clin. 2005 Jul; 1(2):193-205.
Santana LF, Núñez-Durán H, Dilly KW, Lederer WJ. PMID: 17386846.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Alterations in early action potential repolarization causes localized failure of sarcoplasmic reticulum Ca2+ release. Circ Res. 2005 Mar 18; 96(5):543-50.
Harris DM, Mills GD, Chen X, Kubo H, Berretta RM, Votaw VS, Santana LF, Houser SR. PMID: 15705962.
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PubMed Mentions:
43 Fields:
Translation:
AnimalsCells
-
NFATc3 regulates Kv2.1 expression in arterial smooth muscle. J Biol Chem. 2004 Nov 05; 279(45):47326-34.
Amberg GC, Rossow CF, Navedo MF, Santana LF. PMID: 15322114.
View in:
PubMed Mentions:
53 Fields:
Translation:
AnimalsCells
-
NFATc3-induced reductions in voltage-gated K+ currents after myocardial infarction. Circ Res. 2004 May 28; 94(10):1340-50.
Rossow CF, Minami E, Chase EG, Murry CE, Santana LF. PMID: 15087419.
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PubMed Mentions:
46 Fields:
Translation:
AnimalsCells
-
Downregulation of the BK channel beta1 subunit in genetic hypertension. Circ Res. 2003 Nov 14; 93(10):965-71.
Amberg GC, Santana LF. PMID: 14551242.
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PubMed Mentions:
84 Fields:
Translation:
AnimalsCells
-
Modulation of the molecular composition of large conductance, Ca(2+) activated K(+) channels in vascular smooth muscle during hypertension. J Clin Invest. 2003 Sep; 112(5):717-24.
Amberg GC, Bonev AD, Rossow CF, Nelson MT, Santana LF. PMID: 12952920; PMCID: PMC182211.
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PubMed Mentions:
107 Fields:
Translation:
AnimalsCells
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Alkaline pH shifts Ca2+ sparks to Ca2+ waves in smooth muscle cells of pressurized cerebral arteries. Am J Physiol Heart Circ Physiol. 2002 Dec; 283(6):H2169-76.
Heppner TJ, Bonev AD, Santana LF, Nelson MT. PMID: 12427589.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Functional coupling of calcineurin and protein kinase A in mouse ventricular myocytes. J Physiol. 2002 Oct 01; 544(Pt 1):57-69.
Santana LF, Chase EG, Votaw VS, Nelson MT, Greven R. PMID: 12356880; PMCID: PMC2290559.
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PubMed Mentions:
49 Fields:
Translation:
AnimalsCells
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Local Ca(2+) signaling and EC coupling in heart: Ca(2+) sparks and the regulation of the [Ca(2+)](i) transient. J Mol Cell Cardiol. 2002 Aug; 34(8):941-50.
Guatimosim S, Dilly K, Santana LF, Saleet Jafri M, Sobie EA, Lederer WJ. PMID: 12234764.
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PubMed Mentions:
42 Fields:
Translation:
AnimalsCells
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Probing the effects of membrane cholesterol in the Torpedo californica acetylcholine receptor and the novel lipid-exposed mutation alpha C418W in Xenopus oocytes. J Biol Chem. 2001 Dec 07; 276(49):46523-32.
Santiago J, Guzmàn GR, Rojas LV, Marti R, Asmar-Rovira GA, Santana LF, McNamee M, Lasalde-Dominicci JA. PMID: 11567020.
View in:
PubMed Mentions:
36 Fields:
Translation:
AnimalsCells
-
Role of phospholamban in the modulation of arterial Ca(2+) sparks and Ca(2+)-activated K(+) channels by cAMP. Am J Physiol Cell Physiol. 2001 Sep; 281(3):C1029-37.
Wellman GC, Santana LF, Bonev AD, Nelson MT. PMID: 11502581.
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PubMed Mentions:
41 Fields:
Translation:
AnimalsCells
-
Differential contribution of sialic acid to the function of repolarizing K(+) currents in ventricular myocytes. Am J Physiol Cell Physiol. 2001 Aug; 281(2):C464-74.
Ufret-Vincenty CA, Baro DJ, Santana LF. PMID: 11443045.
View in:
PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
-
Role of sodium channel deglycosylation in the genesis of cardiac arrhythmias in heart failure. J Biol Chem. 2001 Jul 27; 276(30):28197-203.
Ufret-Vincenty CA, Baro DJ, Lederer WJ, Rockman HA, Quinones LE, Santana LF. PMID: 11369778.
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PubMed Mentions:
66 Fields:
Translation:
HumansAnimalsCells
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Cellular and functional defects in a mouse model of heart failure. Am J Physiol Heart Circ Physiol. 2000 Dec; 279(6):H3101-12.
Esposito G, Santana LF, Dilly K, Cruz JD, Mao L, Lederer WJ, Rockman HA. PMID: 11087268.
View in:
PubMed Mentions:
40 Fields:
Translation:
AnimalsCells
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Design, synthesis, conformational analysis and biological activities of purine-based 1,2-di-substituted carbocyclic nucleosides. Chem Pharm Bull (Tokyo). 2000 Feb; 48(2):293-5.
Teran C, Santana L, Teijeira M, Uriarte E, De Clercq E. PMID: 10705524.
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PubMed Mentions: Fields:
Translation:
Cells
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Transgenic expression of replication-restricted enteroviral genomes in heart muscle induces defective excitation-contraction coupling and dilated cardiomyopathy. J Clin Invest. 1998 Oct 01; 102(7):1444-53.
Wessely R, Klingel K, Santana LF, Dalton N, Hongo M, Jonathan Lederer W, Kandolf R, Knowlton KU. PMID: 9769337; PMCID: PMC508992.
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PubMed Mentions:
46 Fields:
Translation:
AnimalsCells
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Synthesis and chemotherapeutic activity of a carbocyclic analogue of tegafur. Pharmazie. 1998 Sep; 53(9):644.
Terán C, Santana L, Teijeira M, Uriarte E, Balzarini J, De Clercq E. PMID: 9770214.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Ca2+ flux through promiscuous cardiac Na+ channels: slip-mode conductance. Science. 1998 Feb 13; 279(5353):1027-33.
Santana LF, Gómez AM, Lederer WJ. PMID: 9461434.
View in:
PubMed Mentions:
37 Fields:
Translation:
AnimalsCells
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Calcium sparks and excitation-contraction coupling in phospholamban-deficient mouse ventricular myocytes. J Physiol. 1997 Aug 15; 503 ( Pt 1):21-9.
Santana LF, Kranias EG, Lederer WJ. PMID: 9288671; PMCID: PMC1159883.
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PubMed Mentions:
51 Fields:
Translation:
AnimalsCells
-
Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure. Science. 1997 May 02; 276(5313):800-6.
Gómez AM, Valdivia HH, Cheng H, Lederer MR, Santana LF, Cannell MB, McCune SA, Altschuld RA, Lederer WJ. PMID: 9115206.
View in:
PubMed Mentions:
222 Fields:
Translation:
AnimalsCells
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Amount of calcium in the sarcoplasmic reticulum: influence on excitation-contraction coupling in heart muscle. Heart Vessels. 1997; Suppl 12:44-9.
Santana LF, Gómez AM, Kranias EG, Lederer WJ. PMID: 9476542.
View in:
PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
-
Two mechanisms of quantized calcium release in skeletal muscle. Nature. 1996 Feb 01; 379(6564):455-8.
Klein MG, Cheng H, Santana LF, Jiang YH, Lederer WJ, Schneider MF. PMID: 8559251.
View in:
PubMed Mentions:
146 Fields:
Translation:
Animals
-
Relation between the sarcolemmal Ca2+ current and Ca2+ sparks and local control theories for cardiac excitation-contraction coupling. Circ Res. 1996 Jan; 78(1):166-71.
Santana LF, Cheng H, Gómez AM, Cannell MB, Lederer WJ. PMID: 8603501.
View in:
PubMed Mentions:
92 Fields:
Translation:
AnimalsCells
-
Relaxation of arterial smooth muscle by calcium sparks. Science. 1995 Oct 27; 270(5236):633-7.
Nelson MT, Cheng H, Rubart M, Santana LF, Bonev AD, Knot HJ, Lederer WJ. PMID: 7570021.
View in:
PubMed Mentions:
523 Fields:
Translation:
AnimalsCells