Geoanna Bautista

Title(s)Assistant Professor, MED: Pediatrics
SchoolSchool of Medicine
ORCID ORCID Icon0000-0003-0245-9272 Additional info
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    Targeting Mechanosensitive Signaling Pathways to Modulate Gastroschisis-Related Intestinal Inflammation and Dysmotility (GRIID)
    The Hartwell Foundation A24-0129Apr 1, 2023 - Apr 30, 2025
    Role: Principal Investigator
    Description: My overarching aim is to characterize and elucidate the mechanosensitive signaling mechanisms driving the inflammation-mediated damage that occurs in gastroschisis, with the secondary goal of identifying novel therapeutic targets that can be modulated in utero to mitigate the gastroschisis-related intestinal inflammation and dysmotility (GRIID).
    Determining the role of mechanosensitive Piezo1 in the developing gut
    Children's Miracle Network (CMN) S-CMN2022Jun 1, 2022 - May 30, 2024
    Role: Principal Investigator
    Description: The overarching aim of this grant is to establish the functional expression of Piezo1 in the developing gut to elucidate the signaling mechanisms necessary for intestinal development. My long-term goal is to define the role of Piezo1 mediated mechanosensation in the developing gut to establish novel therapeutic targets for NEC and related gut disorders affecting the neonate.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Smooth muscle cell Piezo1 depletion results in impaired contractile properties in murine small bowel. Commun Biol. 2025 Mar 17; 8(1):448. Bautista GM, Du Y, Matthews MJ, Flores AM, Kushnir NR, Sweeney NK, Nguyen NPN, Tokhtaeva E, Solorzano-Vargas RS, Lewis M, Stelzner M, He X, Dunn JCY, Martin MG. PMID: 40097724; PMCID: PMC11914552.
      View in: PubMed   Mentions:
    2. Spring-mediated distraction enterogenesis may alter the course of adaptation in porcine short bowel syndrome. Front Gastroenterol (Lausanne). 2024; 3. Bautista GM, Dubrovsky G, Sweeney NK, Solórzano-Vargas RS, Tancredi DJ, Lewis M, Stelzner M, Martín MG, Dunn JCY. PMID: 39044860; PMCID: PMC11265786.
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    3. Paneth cell ontogeny in term and preterm ovine models. Front Vet Sci. 2024; 11:1275293. Bautista GM, Cera AJ, Schoenauer RJ, Persiani M, Lakshminrusimha S, Chandrasekharan P, Gugino SF, Underwood MA, McElroy SJ. PMID: 38318150; PMCID: PMC10839032.
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    4. Acute Bowel Ischemia in a Premature Neonate with Miller-Dieker Syndrome and Anomalous Right Coronary Artery From the Pulmonary Artery. Pediatr Ann. 2023 Aug; 52(8):e283-e291. Cera AJ, Mokha S, Sunderji S, Cortez D, Bautista GM. PMID: 37561828; PMCID: PMC10878796.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. State-of-the-art review and update of in vivo models of necrotizing enterocolitis. Front Pediatr. 2023; 11:1161342. Bautista GM, Cera AJ, Chaaban H, McElroy SJ. PMID: 37082706; PMCID: PMC10112335.
      View in: PubMed   Mentions: 3  
    6. Congenital Syphilis Epidemiology, Prevention, and Management in the United States: A 2022 Update. Cureus. 2022 Dec; 14(12):e33009. Fang J, Partridge E, Bautista GM, Sankaran D. PMID: 36712768; PMCID: PMC9879571.
      View in: PubMed   Mentions: 6  
    7. Overview of Congenital Hypopituitarism for the Neonatologist. Neoreviews. 2022 05 01; 23(5):e300-e310. Bautista G. PMID: 35490188.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    8. Craniosynostosis: Neonatal Perspectives. Neoreviews. 2021 04; 22(4):e250-e257. Bautista G. PMID: 33795400.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
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