Meijuan Tu

Title(s)Assistant Scientist, Biochemistry and Molecular Medicine
SchoolSchool of Medicine
Address2700 STOCKTON BLVD., SUIT 2120B
CA 95817
Phone916-734-4848
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Novel RNA molecular bioengineering technology efficiently produces functional miRNA agents. RNA. 2024 Mar 01. Traber GM, Yi C, Batra N, Tu M, Yu A. PMID: 38429100.
      View in: PubMed   Mentions:    Fields:    
    2. A predictive model combining clinical characteristics and nutritional risk factors for overall survival after umbilical cord blood transplantation. Stem Cell Res Ther. 2023 10 23; 14(1):304. Tu M, Huang A, Ning L, Tang B, Zhang C, Sun G, Wan X, Song K, Yao W, Qiang P, Wu Y, Zhu X. PMID: 37872622; PMCID: PMC10594692.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Use of recombinant microRNAs as antimetabolites to inhibit human non-small cell lung cancer. Acta Pharm Sin B. 2023 Oct; 13(10):4273-4290. Chen Y, Tu MJ, Han F, Liu Z, Batra N, Lara PN, Chen HW, Bi H, Yu AM. PMID: 37799388; PMCID: PMC10547963.
      View in: PubMed   Mentions:
    4. Recent Advances in Novel Recombinant RNAs for Studying Post-transcriptional Gene Regulation in Drug Metabolism and Disposition. Curr Drug Metab. 2023; 24(3):175-189. Tu MJ, Yu AM. PMID: 37170982; PMCID: PMC10825985.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. ATR Inhibition in Advanced Urothelial Carcinoma. Clin Genitourin Cancer. 2023 04; 21(2):203-207. Leibrandt RC, Tu MJ, Yu AM, Lara PN, Parikh M. PMID: 36604210; PMCID: PMC10750798.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    6. Unrelated cord blood transplantation vs. HLA-matched sibling transplantation for adults with B-cell acute lymphoblastic leukemia in complete remission: superior OS for patients with long-term survival. Stem Cell Res Ther. 2022 10 09; 13(1):500. Sun G, Tang B, Song K, Wu Y, Tu M, Wan X, Yao W, Geng L, Qiang P, Zhu X. PMID: 36210439; PMCID: PMC9549614.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. The clinical influence of preformed nonspecific anti-HLA antibodies on single-unit umbilical cord blood transplantation in patients with haematological malignancies. Br J Haematol. 2022 08; 198(4):e63-e66. Wu Y, Tang B, Song K, Sun G, Tu M, Wan X, Yao W, Qiang P, Pan T, Ding P, Zhu X. PMID: 35715873.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Allogeneic double-negative T cell therapy for relapsed acute myeloid leukemia patients post allogeneic hematopoietic stem cell transplantation: A first-in-human phase I study. Am J Hematol. 2022 07; 97(7):E264-E267. Tang B, Lee JB, Cheng S, Pan T, Yao W, Wang D, Tu M, Xiang Z, Chu X, Geng L, Qiang P, Teng P, Sun G, Liu H, Wang J, Schimmer AD, Yang L, Sun Z, Zhang L, Zhu X. PMID: 35385187.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    9. Bioengineered RNA Therapy in Patient-Derived Organoids and Xenograft Mouse Models. Methods Mol Biol. 2022; 2521:191-206. Tu MJ, Yi CM, Traber GM, Yu AM. PMID: 35732999; PMCID: PMC9484490.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    10. Chimeric Antigen Receptor T Cell Therapy followed by Unrelated Cord Blood Transplantation for the Treatment of Relapsed/Refractory B Cell Acute Lymphoblastic Leukemia in Children and Young Adults: Superior Survival but Relatively High Post-Transplantation Relapse. Transplant Cell Ther. 2022 02; 28(2):71.e1-71.e8. Sun G, Tang B, Wan X, Yao W, Song K, Tu M, Geng L, Qiang P, Wu Y, Zhu L, Wu Y, Liu H, Zhu X, Sun Z. PMID: 34839013.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    11. Poor survival and prediction of prolonged isolated thrombocytopenia post umbilical cord blood transplantation in patients with hematological malignancies. Hematol Oncol. 2022 Feb; 40(1):82-91. Wu Y, Zhang Z, Tu M, Pan T, Ding P, Tang B, Wan X, Yao W, Song K, Sun G, Geng L, Qiang P, Liu H, Zhu X, Sun Z. PMID: 34664735.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    12. Deliver the promise: RNAs as a new class of molecular entities for therapy and vaccination. Pharmacol Ther. 2022 02; 230:107967. Yu AM, Tu MJ. PMID: 34403681; PMCID: PMC9477512.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCellsPHPublic Health
    13. A Novel Integrated Pharmacokinetic-Pharmacodynamic Model to Evaluate Combination Therapy and Determine In Vivo Synergism. J Pharmacol Exp Ther. 2021 06; 377(3):305-315. Choi YH, Zhang C, Liu Z, Tu MJ, Yu AX, Yu AM. PMID: 33712506; PMCID: PMC8140393.
      View in: PubMed   Mentions: 5     Fields:    
    14. Single bioengineered ncRNA molecule for dual-targeting toward the control of non-small cell lung cancer patient-derived xenograft tumor growth. Biochem Pharmacol. 2021 07; 189:114392. Petrek H, Yan Ho P, Batra N, Tu MJ, Zhang Q, Qiu JX, Yu AM. PMID: 33359565; PMCID: PMC8187260.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    15. Expression and Purification of tRNA/ pre-miRNA-Based Recombinant Noncoding RNAs. Methods Mol Biol. 2021; 2323:249-265. Tu MJ, Wright HK, Batra N, Yu AM. PMID: 34086286; PMCID: PMC9516694.
      View in: PubMed   Mentions: 4     Fields:    Translation:CellsPHPublic Health
    16. Pharmacokinetic and Pharmacodynamic Factors Contribute to Synergism between Let-7c-5p and 5-Fluorouracil in Inhibiting Hepatocellular Carcinoma Cell Viability. Drug Metab Dispos. 2020 12; 48(12):1257-1263. Jilek JL, Tu MJ, Zhang C, Yu AM. PMID: 33051247; PMCID: PMC7684025.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    17. MicroRNA-1291-5p Sensitizes Pancreatic Carcinoma Cells to Arginine Deprivation and Chemotherapy through the Regulation of Arginolysis and Glycolysis. Mol Pharmacol. 2020 12; 98(6):686-694. Tu MJ, Duan Z, Liu Z, Zhang C, Bold RJ, Gonzalez FJ, Kim EJ, Yu AM. PMID: 33051382; PMCID: PMC7673485.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    18. RNA Drugs and RNA Targets for Small Molecules: Principles, Progress, and Challenges. Pharmacol Rev. 2020 10; 72(4):862-898. Yu AM, Choi YH, Tu MJ. PMID: 32929000; PMCID: PMC7495341.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansCellsPHPublic Health
    19. A novel miR-1291-ERRα-CPT1C axis modulates tumor cell proliferation, metabolism and tumorigenesis. Theranostics. 2020; 10(16):7193-7210. Chen Y, Zhou Y, Han F, Zhao Y, Tu M, Wang Y, Huang C, Fan S, Chen P, Yao X, Guan L, Yu AM, Gonzalez FJ, Huang M, Bi H. PMID: 32641987; PMCID: PMC7330864.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    20. Novel approaches for efficient  in vivo fermentation production of noncoding RNAs. Appl Microbiol Biotechnol. 2020 Mar; 104(5):1927-1937. Yu AM, Batra N, Tu MJ, Sweeney C. PMID: 31953559; PMCID: PMC7385725.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    21. Bioengineering of a single long noncoding RNA molecule that carries multiple small RNAs. Appl Microbiol Biotechnol. 2019 Aug; 103(15):6107-6117. Petrek H, Batra N, Ho PY, Tu MJ, Yu AM. PMID: 31187211; PMCID: PMC7068804.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    22. A reliable LC-MS/MS method for the quantification of natural amino acids in mouse plasma: Method validation and application to a study on amino acid dynamics during hepatocellular carcinoma progression. J Chromatogr B Analyt Technol Biomed Life Sci. 2019 Aug 15; 1124:72-81. Liu Z, Tu MJ, Zhang C, Jilek JL, Zhang QY, Yu AM. PMID: 31177050; PMCID: PMC6626562.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    23. Novel Synergistic Combination of Mitotic Arrest and Promotion of Apoptosis for Treatment of Pancreatic Adenocarcinoma. Transl Oncol. 2019 Apr; 12(4):683-692. Duan Z, Chinn D, Tu MJ, Zhang QY, Huynh J, Chen J, Mack P, Yu AM, Kim EJ. PMID: 30844579; PMCID: PMC6402293.
      View in: PubMed   Mentions: 8  
    24. Bioengineered Let-7c Inhibits Orthotopic Hepatocellular Carcinoma and Improves Overall Survival with Minimal Immunogenicity. Mol Ther Nucleic Acids. 2019 Mar 01; 14:498-508. Jilek JL, Zhang QY, Tu MJ, Ho PY, Duan Z, Qiu JX, Yu AM. PMID: 30753993; PMCID: PMC6370598.
      View in: PubMed   Mentions: 25  
    25. RNA therapy: Are we using the right molecules? Pharmacol Ther. 2019 04; 196:91-104. Yu AM, Jian C, Yu AH, Tu MJ. PMID: 30521885; PMCID: PMC6450780.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimals
    26. Co-administration of nuciferine reduces the concentration of metformin in liver via differential inhibition of hepatic drug transporter OCT1 and MATE1. Biopharm Drug Dispos. 2018 Nov; 39(9):411-419. Li L, Lei H, Wang W, Du W, Yuan J, Tu M, Zhou H, Zeng S, Jiang H. PMID: 30294927.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    27. Bioengineered miRNA-1291 prodrug therapy in pancreatic cancer cells and patient-derived xenograft mouse models. Cancer Lett. 2019 02 01; 442:82-90. Tu MJ, Ho PY, Zhang QY, Jian C, Qiu JX, Kim EJ, Bold RJ, Gonzalez FJ, Bi H, Yu AM. PMID: 30389433; PMCID: PMC6311422.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    28. Lipidation of polyethylenimine-based polyplex increases serum stability of bioengineered RNAi agents and offers more consistent tumoral gene knockdown in vivo. Int J Pharm. 2018 Aug 25; 547(1-2):537-544. Zhang QY, Ho PY, Tu MJ, Jilek JL, Chen QX, Zeng S, Yu AM. PMID: 29894758; PMCID: PMC6388695.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    29. Bioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer Therapy. J Pharmacol Exp Ther. 2018 06; 365(3):494-506. Ho PY, Duan Z, Batra N, Jilek JL, Tu MJ, Qiu JX, Hu Z, Wun T, Lara PN, DeVere White RW, Chen HW, Yu AM. PMID: 29602831; PMCID: PMC5931433.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    30. Bioengineered NRF2-siRNA Is Effective to Interfere with NRF2 Pathways and Improve Chemosensitivity of Human Cancer Cells. Drug Metab Dispos. 2018 01; 46(1):2-10. Li PC, Tu MJ, Ho PY, Jilek JL, Duan Z, Zhang QY, Yu AX, Yu AM. PMID: 29061583; PMCID: PMC5733456.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    31. MicroRNA-1291 targets the FOXA2-AGR2 pathway to suppress pancreatic cancer cell proliferation and tumorigenesis. Oncotarget. 2016 Jul 19; 7(29):45547-45561. Tu MJ, Pan YZ, Qiu JX, Kim EJ, Yu AM. PMID: 27322206; PMCID: PMC5216741.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    32. MicroRNA Pharmacoepigenetics: Posttranscriptional Regulation Mechanisms behind Variable Drug Disposition and Strategy to Develop More Effective Therapy. Drug Metab Dispos. 2016 Mar; 44(3):308-19. Yu AM, Tian Y, Tu MJ, Ho PY, Jilek JL. PMID: 26566807; PMCID: PMC4767381.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    33. Combination therapy with bioengineered miR-34a prodrug and doxorubicin synergistically suppresses osteosarcoma growth. Biochem Pharmacol. 2015 Dec 15; 98(4):602-13. Zhao Y, Tu MJ, Yu YF, Wang WP, Chen QX, Qiu JX, Yu AX, Yu AM. PMID: 26518752; PMCID: PMC4725324.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    34. Chimeric MicroRNA-1291 Biosynthesized Efficiently in Escherichia coli Is Effective to Reduce Target Gene Expression in Human Carcinoma Cells and Improve Chemosensitivity. Drug Metab Dispos. 2015 Jul; 43(7):1129-36. Li MM, Addepalli B, Tu MJ, Chen QX, Wang WP, Limbach PA, LaSalle JM, Zeng S, Huang M, Yu AM. PMID: 25934574; PMCID: PMC4468437.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    35. Simple and rapid determination of unsaturated fatty acids in 1 µl of rat plasma by LC-MS/MS. Bioanalysis. 2015; 7(9):1081-91. Zheng S, Ma Z, Song F, Ye J, Wang R, Tu M, Li L, Zhou H, Zeng S, Jiang H. PMID: 26039806.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    36. Involvement of organic cation transporter 1 and CYP3A4 in retrorsine-induced toxicity. Toxicology. 2014 Aug 01; 322:34-42. Tu M, Li L, Lei H, Ma Z, Chen Z, Sun S, Xu S, Zhou H, Zeng S, Jiang H. PMID: 24799337.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    37. The contribution of human OCT1, OCT3, and CYP3A4 to nitidine chloride-induced hepatocellular toxicity. Drug Metab Dispos. 2014 Jul; 42(7):1227-34. Li L, Tu M, Yang X, Sun S, Wu X, Zhou H, Zeng S, Jiang H. PMID: 24778366.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    38. Involvement of organic cation transporter 2 inhibition in potential mechanisms of antidepressant action. Prog Neuropsychopharmacol Biol Psychiatry. 2014 Aug 04; 53:90-8. Wang K, Sun S, Li L, Tu M, Jiang H. PMID: 24657329.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    39. In vitro interaction of clopidogrel and its hydrolysate with OCT1, OCT2 and OAT1. Int J Pharm. 2014 Apr 25; 465(1-2):5-10. Li L, Song F, Tu M, Wang K, Zhao L, Wu X, Zhou H, Xia Z, Jiang H. PMID: 24530383.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    40. Inhibition of organic cation transporter 2 and 3 may be involved in the mechanism of the antidepressant-like action of berberine. Prog Neuropsychopharmacol Biol Psychiatry. 2014 Mar 03; 49:1-6. Sun S, Wang K, Lei H, Li L, Tu M, Zeng S, Zhou H, Jiang H. PMID: 24246570.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    41. Organic cation transporter 1 mediates the uptake of monocrotaline and plays an important role in its hepatotoxicity. Toxicology. 2013 Sep 15; 311(3):225-30. Tu M, Sun S, Wang K, Peng X, Wang R, Li L, Zeng S, Zhou H, Jiang H. PMID: 23831208.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    42. The exposure of luteolin is much lower than that of apigenin in oral administration of Flos Chrysanthemi extract to rats. Drug Metab Pharmacokinet. 2012; 27(1):162-8. Chen Z, Tu M, Sun S, Kong S, Wang Y, Ye J, Li L, Zeng S, Jiang H. PMID: 21931223.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
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