Su Guan

Title(s)Associate Specialist, Biochemistry and Molecular Medicine
SchoolSchool of Medicine
ORCID ORCID Icon0000-0001-8130-7597 Additional info
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Lipidomics Study of Sepsis-Induced Liver and Lung Injury under Anti-HMGB1 Intervention. J Proteome Res. 2023 06 02; 22(6):1881-1895. Huang J, Wang Z, Zhang X, Gou Y, Li J, Guan S, Zhang H. PMID: 37000907.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    2. UPLC-QTOF-MS Based Comparison of Rotundic Acid Metabolic Profiles in Normal and NAFLD Rats. Metabolites. 2022 Dec 26; 13(1). Wu L, Xing L, Zou Y, Wang Z, Gou Y, Zhang L, Guan S. PMID: 36676962.
      View in: PubMed   Mentions:
    3. Asiatic acid alleviates liver fibrosis via multiple signaling pathways based on integrated network pharmacology and lipidomics. Eur J Pharmacol. 2022 Sep 15; 931:175193. Li Y, He XL, Zhou LP, Huang XZ, Li S, Guan S, Li J, Zhang L. PMID: 35963324.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    4. Peptide identification of hepatocyte growth-promoting factor and its function in cytoprotection and promotion of liver cell proliferation through the JAK2/STAT3/c-MYC pathway. Eur J Pharmacol. 2022 Apr 05; 920:174832. Jiang QY, Lin ZL, Su ZW, Li S, Li J, Guan S, Ling Y, Zhang L. PMID: 35183533.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    5. UPLC-Q-TOF/MS-Based Plasma and Urine Metabolomics Contribute to the Diagnosis of Sepsis. J Proteome Res. 2022 01 07; 21(1):209-219. Guan S, Liu K, Liu Z, Zhou L, Jia B, Wang Z, Nie Y, Zhang X. PMID: 34941272.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    6. UPLC-MS-Based Serum Metabolic Profiling Reveals Potential Biomarkers for Predicting Propofol Responsiveness in Females. J Proteome Res. 2021 09 03; 20(9):4578-4588. Li R, Yang L, Guan S, Lin M, Lai H, Liu K, Liu Z, Zhang X. PMID: 34384217.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. Ultraperformance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry-Based Metabolomics and Lipidomics Identify Biomarkers for Efficacy Evaluation of Mesalazine in a Dextran Sulfate Sodium-Induced Ulcerative Colitis Mouse Model. J Proteome Res. 2021 02 05; 20(2):1371-1381. Liu K, Jia B, Zhou L, Xing L, Wu L, Li Y, Lu J, Zhang L, Guan S. PMID: 33356298.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    8. UPLC-QTOF-MS-Based Plasma Lipidomic Profiling Reveals Biomarkers for Inflammatory Bowel Disease Diagnosis. J Proteome Res. 2020 02 07; 19(2):600-609. Guan S, Jia B, Chao K, Zhu X, Tang J, Li M, Wu L, Xing L, Liu K, Zhang L, Wang X, Gao X, Huang M. PMID: 31821004.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    9. Rotundic Acid Induces DNA Damage and Cell Death in Hepatocellular Carcinoma Through AKT/mTOR and MAPK Pathways. Front Oncol. 2019; 9:545. Roy G, Guan S, Liu H, Zhang L. PMID: 31293977; PMCID: PMC6606729.
      View in: PubMed   Mentions: 7  
    10. Identification and structural characterization of febuxostat metabolites in rat serum and urine samples using UHPLC-QTOF/MS. Biomed Chromatogr. 2019 Sep; 33(9):e4568. Zhou L, Liu H, Xu Z, Guan S, Zhang L. PMID: 31042300.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    11. Pharmacokinetic and metabolic studies of Vortioxetine in rats using ultra high performance liquid chromatography with tandem mass spectrometry. J Sep Sci. 2018 Dec; 41(24):4469-4479. Guan S, Zou Y, Jia B, Wu L, Yang Z, Yuan F, Zhang L. PMID: 30354005.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    12. Activation of PD-1 Protects Intestinal Immune Defense Through IL-10/miR-155 Pathway After Intestinal Ischemia Reperfusion. Dig Dis Sci. 2018 12; 63(12):3307-3316. Zhang XY, Guan S, Zhang HF, Li RY, Liu ZM. PMID: 30206757.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    13. Propofol Does Not Reduce Pyroptosis of Enterocytes and Intestinal Epithelial Injury After Lipopolysaccharide Challenge. Dig Dis Sci. 2018 01; 63(1):81-91. Zhang XY, Chen X, Zhang HF, Guan S, Wen SH, Huang WQ, Liu ZM. PMID: 29063417.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    14. Intervertebral Foramen Injection of Ozone Relieves Mechanical Allodynia and Enhances Analgesic Effect of Gabapentin in Animal Model of Neuropathic Pain. Pain Physician. 2017 07; 20(5):E673-E685. Luo WJ, Yang F, Yang F, Sun W, Zheng W, Wang XL, Wu FF, Wang JL, Wang JS, Guan SM, Chen J. PMID: 28727712.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    15. An Investigation Into Vortioxetine Salts: Crystal Structure, Thermal Stability, and Solubilization. J Pharm Sci. 2016 07; 105(7):2123-8. He SF, Zhang XR, Zhang S, Guan S, Li J, Li S, Zhang L. PMID: 27262207.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    16. Genetic markers in CYP2C19 and CYP2B6 for prediction of cyclophosphamide's 4-hydroxylation, efficacy and side effects in Chinese patients with systemic lupus erythematosus. Br J Clin Pharmacol. 2016 Feb; 81(2):327-40. Shu W, Guan S, Yang X, Liang L, Li J, Chen Z, Zhang Y, Chen L, Wang X, Huang M. PMID: 26456622; PMCID: PMC4833150.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCTClinical Trials
    17. Highly selective and sensitive fluorescence chemosensor for the detection of palladium species based on Tsuji-Trost reaction. Spectrochim Acta A Mol Biomol Spectrosc. 2015 Sep 05; 148:7-11. Xu ZY, Li J, Guan S, Zhang L, Dong CZ. PMID: 25863454.
      View in: PubMed   Mentions:    Fields:    
    18. Comparative pharmacokinetics and bile transformation of R-enantiomer and racemic bambuterol after single-dose intravenous, oral administration in rats and beagle dogs. Eur J Drug Metab Pharmacokinet. 2015 Dec; 40(4):453-60. Guan S, Hu CY, He MY, Yang YY, Tang YX, Chen JD, Huang LJ, Tan W. PMID: 25281237.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    19. E3-ligase Skp2 predicts poor prognosis and maintains cancer stem cell pool in nasopharyngeal carcinoma. Oncotarget. 2014 Jul 30; 5(14):5591-601. Wang J, Huang Y, Guan Z, Zhang JL, Su HK, Zhang W, Yue CF, Yan M, Guan S, Liu QQ. PMID: 25015320; PMCID: PMC4170633.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    20. Triptolide synergistically enhances temozolomide-induced apoptosis and potentiates inhibition of NF-κB signaling in glioma initiating cells. Am J Chin Med. 2014; 42(2):485-503. Sai K, Li WY, Chen YS, Wang J, Guan S, Yang QY, Guo CC, Mou YG, Li WP, Chen ZP. PMID: 24707876.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    21. Cryptotanshinone Ameliorates Hepatic Normothermic Ischemia and Reperfusion Injury in Rats by Anti-mitochondrial Apoptosis. Biol Pharm Bull. 2014; 37(11):1758-65. Sun PP, Yuan F, Xu J, Sai K, Chen J, Guan S. PMID: 25366482.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    22. Wedelolactone inhibits LPS-induced pro-inflammation via NF-kappaB pathway in RAW 264.7 cells. J Biomed Sci. 2013 Oct 31; 20:84. Yuan F, Chen J, Sun PP, Guan S, Xu J. PMID: 24176090; PMCID: PMC4174895.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    23. Neurosurgical interventions for patients with nasopharyngeal carcinoma: a single institution experience. World J Surg Oncol. 2013 Sep 13; 11:227. Sai K, Mou YG, Zeng J, Lv YC, Xi SY, Guan S, Zhang XH, Wang J, Ke C, Guo JG, Chen YS, Chen ZP. PMID: 24034781; PMCID: PMC3847299.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    24. Induction of cell-cycle arrest and apoptosis in glioblastoma stem-like cells by WP1193, a novel small molecule inhibitor of the JAK2/STAT3 pathway. J Neurooncol. 2012 May; 107(3):487-501. Sai K, Wang S, Balasubramaniyan V, Conrad C, Lang FF, Aldape K, Szymanski S, Fokt I, Dasgupta A, Madden T, Guan S, Chen Z, Alfred Yung WK, Priebe W, Colman H. PMID: 22249692.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    25. Nuclear translocation of MRP1 contributes to multidrug resistance of mucoepidermoid carcinoma. Oral Oncol. 2011 Dec; 47(12):1134-40. Cai BL, Xu XF, Fu SM, Shen LL, Zhang J, Guan SM, Wu JZ. PMID: 21903448.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    26. Establishment and characterization of clinically relevant models of ependymoma: a true challenge for targeted therapy. Neuro Oncol. 2011 Jul; 13(7):748-58. Guan S, Shen R, Lafortune T, Tiao N, Houghton P, Yung WK, Koul D. PMID: 21653596; PMCID: PMC3129270.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    27. The biomechanical analysis of simulating implants in function under osteoporotic jawbone by comparing cylindrical, apical tapered, neck tapered, and expandable type implants: a 3-dimensional finite element analysis. J Oral Maxillofac Surg. 2011 Jul; 69(7):e273-81. Xiao JR, Li YF, Guan SM, Song L, Xu LX, Kong L. PMID: 21367505.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    28. Prognostic relevance of Bmi-1 expression and autoantibodies in esophageal squamous cell carcinoma. BMC Cancer. 2010 Sep 01; 10:467. Liu WL, Guo XZ, Zhang LJ, Wang JY, Zhang G, Guan S, Chen YM, Kong QL, Xu LH, Li MZ, Song LB, Zeng MS. PMID: 20809956; PMCID: PMC2942852.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    29. Epstein-Barr virus-encoded LMP2A induces an epithelial-mesenchymal transition and increases the number of side population stem-like cancer cells in nasopharyngeal carcinoma. PLoS Pathog. 2010 Jun 03; 6(6):e1000940. Kong QL, Hu LJ, Cao JY, Huang YJ, Xu LH, Liang Y, Xiong D, Guan S, Guo BH, Mai HQ, Chen QY, Zhang X, Li MZ, Shao JY, Qian CN, Xia YF, Song LB, Zeng YX, Zeng MS. PMID: 20532215; PMCID: PMC2880580.
      View in: PubMed   Mentions: 94     Fields:    Translation:HumansAnimalsCells
    30. Baicalin induces human mucoepidermoid carcinoma Mc3 cells apoptosis in vitro and in vivo. Invest New Drugs. 2011 Aug; 29(4):637-45. Xu XF, Cai BL, Guan SM, Li Y, Wu JZ, Wang Y, Liu B. PMID: 20204673.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    31. Pre-malignant nasopharyngeal epithelial cell models. Ai Zheng. 2009 Oct; 28(10):1012-5. Kong QL, Guan S, Guo BH, Zeng MS. PMID: 19799806.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    32. Impact of the haplotypes of the human pregnane X receptor gene on the basal and St John's wort-induced activity of cytochrome P450 3A4 enzyme. Br J Clin Pharmacol. 2009 Feb; 67(2):255-61. Wang XD, Li JL, Su QB, Guan S, Chen J, Du J, He YW, Zeng J, Zhang JX, Chen X, Huang M, Zhou SF. PMID: 19173680; PMCID: PMC2670384.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    33. Determination of levonorgestrel in human plasma by liquid chromatography-tandem mass spectrometry method: application to a bioequivalence study of two formulations in healthy volunteers. Biomed Chromatogr. 2008 May; 22(5):519-26. Zhao LZ, Zhong GP, Bi HC, Ding L, Deng Y, Guan S, Chen X, Huang ZY, Huang M. PMID: 18254150.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    34. Induction of cytochrome P450 3A by the Ginkgo biloba extract and bilobalides in human and rat primary hepatocytes. Drug Metab Lett. 2008 Jan; 2(1):60-6. Deng Y, Bi HC, Zhao LZ, Wang XD, Chen J, Ou ZM, Ding L, Xu LJ, Guan S, Chen X, Zhou SF, Huang M. PMID: 19356072.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    35. Biotransformation and pharmacokinetics of the novel anticancer drug, SYUIQ-5, in the rat. Invest New Drugs. 2008 Apr; 26(2):119-37. Su QB, He F, Wang XD, Guan S, Xie ZY, Wang LY, Lu YJ, Gu LQ, Huang ZS, Chen X, Huang M, Zhou SF. PMID: 17922078.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    36. Determination of CH330331, a novel 4-anilinoquinazoline inhibitor of epidermal growth factor receptor tyrosine kinase, in human Caco-2 monolayers by high performance liquid chromatography with ultraviolet detection: application to a trans-epithelial transport study. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Jul 01; 854(1-2):320-7. Sun HY, Guan S, Bi HC, Su QB, Huang WL, Chowbay B, Huang M, Chen X, Li CG, Zhou SF. PMID: 17467348.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    37. High performance liquid chromatography with ultraviolet detection for the determination of SYUIQ-5, a novel telomerase inhibitor for cancer therapy: application to an enzyme kinetic study in rat liver microsomes. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Jul 01; 854(1-2):332-7. Su QB, He F, Guan S, Lu YJ, Gu LQ, Huang ZS, Chen X, Huang M, Li CG, Chowbay B, Zhou SF. PMID: 17449337.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    38. Treatment of Streptococcus mutans with antisense oligodeoxyribonucleotides to gtfB mRNA inhibits GtfB expression and function. FEMS Microbiol Lett. 2006 Nov; 264(1):8-14. Guo QY, Xiao G, Li R, Guan SM, Zhu XL, Wu JZ. PMID: 17020543.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    39. Intra- and inter-ethnic differences in the allele frequencies of cytochrome P450 2B6 gene in Chinese. Pharm Res. 2006 Sep; 23(9):1983-90. Guan S, Huang M, Li X, Chen X, Chan E, Zhou SF. PMID: 16951995.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    40. Genetic polymorphisms of cytochrome P450 2B6 gene in Han Chinese. Eur J Pharm Sci. 2006 Sep; 29(1):14-21. Guan S, Huang M, Chan E, Chen X, Duan W, Zhou SF. PMID: 16815693.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    41. A mechanistic study of the intestinal absorption of cryptotanshinone, the major active constituent of Salvia miltiorrhiza. J Pharmacol Exp Ther. 2006 Jun; 317(3):1285-94. Zhang J, Huang M, Guan S, Bi HC, Pan Y, Duan W, Chan SY, Chen X, Hong YH, Bian JS, Yang HY, Zhou S. PMID: 16497784.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    42. [Study on new extraction technology of astragaloside IV]. Zhong Yao Cai. 2005 Aug; 28(8):705-8. Sun H, Guan S, Huang M. PMID: 16379427.
      View in: PubMed   Mentions:    Fields:    Translation:Animals