Valentina Medici

Title(s)Professor, Gastroenterology and Hepatology
SchoolSchool of Medicine
Address3500 PSSB/UCDMC
CA 95817
Phone916-734-3751
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    Collapse Research 
    Collapse Research Activities and Funding
    NRSA Training Core (TL1)
    NIH TL1TR001861Jul 1, 2016 - May 31, 2026
    Role: Principal Investigator
    Epigenetic regulation of Wilson Disease
    NIH R01DK104770Apr 1, 2016 - Mar 31, 2021
    Role: Principal Investigator
    Wilson Disease: Effect of High-Choline Feeding on Fetal and Offspring Mouse Liver
    NIH R03DK099427Jul 1, 2014 - Dec 31, 2016
    Role: Principal Investigator
    Wilson Disease: Regulation of Steatosis by Methionine Metabolism
    NIH K08DK084111Jun 1, 2010 - Aug 31, 2015
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Correction: A caged imidazopyrazinone for selective bioluminescence detection of labile extracellular copper(ii). Chem Sci. 2022 May 18; 13(19):5774. O'Sullivan JJ, Medici V, Heffern MC. PMID: 35694340; PMCID: PMC9116369.
      View in: PubMed   Mentions:
    2. Absorption, distribution, metabolism and excretion of apigenin and its glycosides in healthy male adults. Free Radic Biol Med. 2022 05 20; 185:90-96. Borges G, Fong RY, Ensunsa JL, Kimball J, Medici V, Ottaviani JI, Crozier A. PMID: 35452808.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    3. The Dose-Response Effects of Consuming High Fructose Corn Syrup-Sweetened Beverages on Hepatic Lipid Content and Insulin Sensitivity in Young Adults. Nutrients. 2022 Apr 15; 14(8). Sigala DM, Hieronimus B, Medici V, Lee V, Nunez MV, Bremer AA, Cox CL, Price CA, Benyam Y, Abdelhafez Y, McGahan JP, Keim NL, Goran MI, Pacini G, Tura A, Sirlin CB, Chaudhari AJ, Havel PJ, Stanhope KL. PMID: 35458210; PMCID: PMC9030734.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. A caged imidazopyrazinone for selective bioluminescence detection of labile extracellular copper(ii). Chem Sci. 2022 Apr 13; 13(15):4352-4363. O'Sullivan JJ, Medici V, Heffern MC. PMID: 35509459; PMCID: PMC9006956.
      View in: PubMed   Mentions:
    5. Plasma Oxylipin Profile Discriminates Ethnicities in Subjects with Non-Alcoholic Steatohepatitis: An Exploratory Analysis. Metabolites. 2022 Feb 19; 12(2). Mazi TA, Borkowski K, Fiehn O, Bowlus CL, Sarkar S, Matsukuma K, Ali MR, Kieffer DA, Wan YY, Stanhope KL, Havel PJ, Newman JW, Medici V. PMID: 35208265; PMCID: PMC8875408.
      View in: PubMed   Mentions:
    6. Consuming Sucrose- or HFCS-sweetened Beverages Increases Hepatic Lipid and Decreases Insulin Sensitivity in Adults. J Clin Endocrinol Metab. 2021 10 21; 106(11):3248-3264. Sigala DM, Hieronimus B, Medici V, Lee V, Nunez MV, Bremer AA, Cox CL, Price CA, Benyam Y, Chaudhari AJ, Abdelhafez Y, McGahan JP, Goran MI, Sirlin CB, Pacini G, Tura A, Keim NL, Havel PJ, Stanhope KL. PMID: 34265055; PMCID: PMC8530743.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    7. COVID-19 patients and Dementia: Frontal cortex transcriptomic data. Data Brief. 2021 Oct; 38:107432. Garofalo M, Gagliardi S, Zucca S, Pandini C, Dragoni F, Sproviero D, Pansarasa O, Poloni TE, Medici V, Davin A, Visonà SD, Moretti M, Guaita A, Ceroni M, Tronconi L, Cereda C. PMID: 34604485; PMCID: PMC8479506.
      View in: PubMed   Mentions: 1  
    8. Wilson disease and the differential diagnosis of its hepatic manifestations: a narrative review of clinical, laboratory, and liver histological features. Ann Transl Med. 2021 Sep; 9(17):1394. Schroeder SM, Matsukuma KE, Medici V. PMID: 34733946; PMCID: PMC8506558.
      View in: PubMed   Mentions: 1  
    9. Diagnosis of Wilson Disease and Its Phenotypes by Using Artificial Intelligence. Biomolecules. 2021 08 20; 11(8). Medici V, Czlonkowska A, Litwin T, Giulivi C. PMID: 34439909; PMCID: PMC8394607.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Expression pattern of perilipins in human brain during aging and in Alzheimer's disease. Neuropathol Appl Neurobiol. 2022 02; 48(1):e12756. Conte M, Medici V, Malagoli D, Chiariello A, Cirrincione A, Davin A, Chikhladze M, Vasuri F, Legname G, Ferrer I, Vanni S, Marcon G, Poloni TE, Guaita A, Franceschi C, Salvioli S. PMID: 34312912; PMCID: PMC9291275.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    11. Ethnicity-specific alterations of plasma and hepatic lipidomic profiles are related to high NAFLD rate and severity in Hispanic Americans, a pilot study. Free Radic Biol Med. 2021 08 20; 172:490-502. Mazi TA, Borkowski K, Newman JW, Fiehn O, Bowlus CL, Sarkar S, Matsukuma K, Ali MR, Kieffer DA, Wan YY, Stanhope KL, Havel PJ, Medici V. PMID: 34182070; PMCID: PMC8712226.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    12. COVID-19-related neuropathology and microglial activation in elderly with and without dementia. Brain Pathol. 2021 09; 31(5):e12997. Poloni TE, Medici V, Moretti M, Visonà SD, Cirrincione A, Carlos AF, Davin A, Gagliardi S, Pansarasa O, Cereda C, Tronconi L, Guaita A, Ceroni M. PMID: 34145669; PMCID: PMC8412067.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    13. Wilson Disease: Intersecting DNA Methylation and Histone Acetylation Regulation of Gene Expression in a Mouse Model of Hepatic Copper Accumulation. Cell Mol Gastroenterol Hepatol. 2021; 12(4):1457-1477. Sarode GV, Neier K, Shibata NM, Shen Y, Goncharov DA, Goncharova EA, Mazi TA, Joshi N, Settles ML, LaSalle JM, Medici V. PMID: 34098115; PMCID: PMC8487080.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    14. Detection of SARS-CoV-2 genome and whole transcriptome sequencing in frontal cortex of COVID-19 patients. Brain Behav Immun. 2021 10; 97:13-21. Gagliardi S, Poloni ET, Pandini C, Garofalo M, Dragoni F, Medici V, Davin A, Visonà SD, Moretti M, Sproviero D, Pansarasa O, Guaita A, Ceroni M, Tronconi L, Cereda C. PMID: 34022369; PMCID: PMC8132498.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    15. The Present and Future Challenges of Wilson's Disease Diagnosis and Treatment. Clin Liver Dis (Hoboken). 2021 Apr; 17(4):267-270. Leung M, Aronowitz PB, Medici V. PMID: 33968387; PMCID: PMC8087914.
      View in: PubMed   Mentions: 1  
    16. Corrigendum to "Synergistic effects of fructose and glucose on lipoprotein risk factors for cardiovascular disease in young adults" [Metab Clin Exp 112 (2020) 154356]. Metabolism. 2021 Jun; 119:154774. Hieronimus B, Medici V, Bremer AA, Lee V, Nunez MV, Sigala DM, Keim NL, Havel PJ, Stanhope KL. PMID: 33866221.
      View in: PubMed   Mentions:    Fields:    
    17. Expanding the Diagnostic Toolkit of Wilson Disease with ATP7B Peptides. Gastroenterology. 2021 06; 160(7):2249-2251. Medici V. PMID: 33753100; PMCID: PMC8666137.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. A Pilot Study Comparing the Effects of Consuming 100% Orange Juice or Sucrose-Sweetened Beverage on Risk Factors for Cardiometabolic Disease in Women. Nutrients. 2021 Feb 26; 13(3). Price CA, Medici V, Nunez MV, Lee V, Sigala DM, Benyam Y, Keim NL, Mason AE, Chen SY, Parenti M, Slupsky C, Epel ES, Havel PJ, Stanhope KL. PMID: 33652807; PMCID: PMC7996959.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCTClinical Trials
    19. Poly (ADP-ribose) polymerase 1 and Parkinson's disease: A study in post-mortem human brain. Neurochem Int. 2021 03; 144:104978. Salemi M, Mazzetti S, De Leonardis M, Giampietro F, Medici V, Poloni TE, Cannarella R, Giaccone G, Pezzoli G, Cappelletti G, Ferri R. PMID: 33516746.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    20. Upregulation of Cortical A2A Adenosine Receptors Is Reflected in Platelets of Patients with Alzheimer's Disease. J Alzheimers Dis. 2021; 80(3):1105-1117. Merighi S, Battistello E, Casetta I, Gragnaniello D, Poloni TE, Medici V, Cirrincione A, Varani K, Vincenzi F, Borea PA, Gessi S. PMID: 33646165.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    21. Effects of Consuming Sugar-Sweetened Beverages for 2 Weeks on 24-h Circulating Leptin Profiles, Ad Libitum Food Intake and Body Weight in Young Adults. Nutrients. 2020 Dec 19; 12(12). Sigala DM, Widaman AM, Hieronimus B, Nunez MV, Lee V, Benyam Y, Bremer AA, Medici V, Havel PJ, Stanhope KL, Keim NL. PMID: 33352724; PMCID: PMC7765993.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    22. mtDNA depletion-like syndrome in Wilson disease. Liver Int. 2020 11; 40(11):2776-2787. Medici V, Sarode GV, Napoli E, Song GY, Shibata NM, Guimarães AO, Mordaunt CE, Kieffer DA, Mazi TA, Czlonkowska A, Litwin T, LaSalle JM, Giulivi C. PMID: 32996699; PMCID: PMC8079140.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    23. Synergistic effects of fructose and glucose on lipoprotein risk factors for cardiovascular disease in young adults. Metabolism. 2020 11; 112:154356. Hieronimus B, Medici V, Bremer AA, Lee V, Nunez MV, Sigala DM, Keim NL, Havel PJ, Stanhope KL. PMID: 32916151; PMCID: PMC8744004.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    24. Effects of Dietary Glucose and Fructose on Copper, Iron, and Zinc Metabolism Parameters in Humans. Nutrients. 2020 Aug 25; 12(9). Harder NHO, Hieronimus B, Stanhope KL, Shibata NM, Lee V, Nunez MV, Keim NL, Bremer A, Havel PJ, Heffern MC, Medici V. PMID: 32854403; PMCID: PMC7551875.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    25. Prevalence and prognostic value of Delirium as the initial presentation of COVID-19 in the elderly with dementia: An Italian retrospective study. EClinicalMedicine. 2020 Sep; 26:100490. Poloni TE, Carlos AF, Cairati M, Cutaia C, Medici V, Marelli E, Ferrari D, Galli A, Bognetti P, Davin A, Cirrincione A, Ceretti A, Cereda C, Ceroni M, Tronconi L, Vitali S, Guaita A. PMID: 32838241; PMCID: PMC7392565.
      View in: PubMed   Mentions: 39  
    26. Assessment of plaque morphology in Alzheimer's mouse cerebellum using three-dimensional X-ray phase-based virtual histology. Sci Rep. 2020 07 08; 10(1):11233. Massimi L, Pieroni N, Maugeri L, Fratini M, Brun F, Bukreeva I, Santamaria G, Medici V, Poloni TE, Balducci C, Cedola A. PMID: 32641715; PMCID: PMC7343834.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    27. Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains. J Vis Exp. 2020 06 03; (160). Poloni TE, Medici V, Carlos AF, Davin A, Ceretti A, Mangieri M, Cassini P, Vaccaro R, Zaccaria D, Abbondanza S, Bordoni M, Fantini V, Fogato E, Cereda C, Ceroni M, Guaita A. PMID: 32568219.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    28. Lipid and energy metabolism in Wilson disease. Liver Res. 2020 Mar; 4(1):5-14. Mazi TA, Shibata NM, Medici V. PMID: 32832193; PMCID: PMC7437987.
      View in: PubMed   Mentions: 3  
    29. Switching Pharmacological Treatment in Wilson Disease: Case Report and Recommendations. J Investig Med High Impact Case Rep. 2020 Jan-Dec; 8:2324709619896876. Leung M, Wu Lanzafame J, Medici V. PMID: 31920114; PMCID: PMC6956597.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    30. Correction to: Metabolomics profiles of patients with Wilson disease reveal a distinct metabolic signature. Metabolomics. 2019 Dec 03; 16(1):3. Sarode GV, Kim K, Kieffer DA, Shibata NM, Litwin T, Czlonkowska A, Medici V. PMID: 31797141.
      View in: PubMed   Mentions:    Fields:    
    31. Dysregulated Choline, Methionine, and Aromatic Amino Acid Metabolism in Patients with Wilson Disease: Exploratory Metabolomic Profiling and Implications for Hepatic and Neurologic Phenotypes. Int J Mol Sci. 2019 Nov 26; 20(23). Mazi TA, Sarode GV, Czlonkowska A, Litwin T, Kim K, Shibata NM, Medici V. PMID: 31779102; PMCID: PMC6928853.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    32. Reversible Holmes Tremor due to Middle Cerebral Artery Giant Aneurysm. Tremor Other Hyperkinet Mov (N Y). 2019; 9. Poloni TE, Galli A, Carlos AF, Riva E, Medici V, Davin A, Guaita A, Ceroni M. PMID: 31534828; PMCID: PMC6727859.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    33. Genetics and epigenetic factors of Wilson disease. Ann Transl Med. 2019 Apr; 7(Suppl 2):S58. Medici V, LaSalle JM. PMID: 31179295; PMCID: PMC6531661.
      View in: PubMed   Mentions: 14  
    34. Metabolomics profiles of patients with Wilson disease reveal a distinct metabolic signature. Metabolomics. 2019 03 12; 15(3):43. Sarode GV, Kim K, Kieffer DA, Shibata NM, Litwin T, Czlonkowska A, Medici V. PMID: 30868361; PMCID: PMC6568258.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    35. From brain collections to modern brain banks: A historical perspective. Alzheimers Dement (N Y). 2019; 5:52-60. Carlos AF, Poloni TE, Medici V, Chikhladze M, Guaita A, Ceroni M. PMID: 30775417; PMCID: PMC6365388.
      View in: PubMed   Mentions: 5  
    36. Epigenomic signatures in liver and blood of Wilson disease patients include hypermethylation of liver-specific enhancers. Epigenetics Chromatin. 2019 02 01; 12(1):10. Mordaunt CE, Kieffer DA, Shibata NM, Czlonkowska A, Litwin T, Weiss KH, Zhu Y, Bowlus CL, Sarkar S, Cooper S, Wan YY, Ali MR, LaSalle JM, Medici V. PMID: 30709419; PMCID: PMC6357467.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    37. Hepatocellular Carcinoma and Associated Clinical Features in Latino and Caucasian Patients from a Single Center. Ann Hepatol. 2019 Jan - Feb; 18(1):177-186. Kuftinec GN, Levy R, Kieffer DA, Medici V. PMID: 31113588; PMCID: PMC7092554.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    38. Hepatocellular Carcinoma and Associated Clinical Features in Latino and Caucasian Patients from a Single Center. Ann Hepatol. 2018 Dec 13; 18(1):177-186. Kuftinec GN, Levy R, Kieffer DA, Medici V. PMID: 30596601.
      View in: PubMed   Mentions:
    39. Epigenetic changes of the thioredoxin system in the tx-j mouse model and in patients with Wilson disease. Hum Mol Genet. 2018 11 15; 27(22):3854-3869. Mordaunt CE, Shibata NM, Kieffer DA, Czlonkowska A, Litwin T, Weiss KH, Gotthardt DN, Olson K, Wei D, Cooper S, Wan YY, Ali MR, LaSalle JM, Medici V. PMID: 30010856; PMCID: PMC6216211.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    40. Anastomotic Biliary Stricture Development after Liver Transplantation in the Setting of Retained Prophylactic Intraductal Pediatric Feeding Tube: Case and Review. Case Reports Hepatol. 2018; 2018:4707389. Koo PT, Medici V, Tabibian JH. PMID: 30363933; PMCID: PMC6186356.
      View in: PubMed   Mentions: 2  
    41. Wilson disease. Nat Rev Dis Primers. 2018 09 06; 4(1):21. Czlonkowska A, Litwin T, Dusek P, Ferenci P, Lutsenko S, Medici V, Rybakowski JK, Weiss KH, Schilsky ML. PMID: 30190489; PMCID: PMC6416051.
      View in: PubMed   Mentions: 126     Fields:    Translation:Humans
    42. Nutritional Ketosis for Weight Management and Reversal of Metabolic Syndrome. Curr Nutr Rep. 2018 09; 7(3):97-106. Gershuni VM, Yan SL, Medici V. PMID: 30128963; PMCID: PMC6472268.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    43. Impact of Energy Drinks on Health and Well-being. Curr Nutr Rep. 2018 09; 7(3):121-130. Sankararaman S, Syed W, Medici V, Sferra TJ. PMID: 29982915.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    44. Plasma fatty acid ethanolamides are associated with postprandial triglycerides, ApoCIII, and ApoE in humans consuming a high-fructose corn syrup-sweetened beverage. Am J Physiol Endocrinol Metab. 2018 08 01; 315(2):E141-E149. Price CA, Argueta DA, Medici V, Bremer AA, Lee V, Nunez MV, Chen GX, Keim NL, Havel PJ, Stanhope KL, DiPatrizio NV. PMID: 29634315; PMCID: PMC6335011.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    45. Clinical features of alcoholic hepatitis in latinos and caucasians: A single center experience. World J Gastroenterol. 2017 Oct 28; 23(40):7274-7282. Pinon-Gutierrez R, Durbin-Johnson B, Halsted CH, Medici V. PMID: 29142474; PMCID: PMC5677196.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    46. Nutritional Risk Factors in the Pathogenesis of Parenteral Nutrition-Associated Liver Disease. Current Nutrition Reports. 2017 Sep 1; 6(3):281-290. Limketkai LB, Choe CM, Patel PS, Shah SN, Medici MV. .
      View in: Publisher Site   Mentions:
    47. Wilson disease: At the crossroads between genetics and epigenetics-A review of the evidence. Liver Res. 2017 Sep; 1(2):121-130. Kieffer DA, Medici V. PMID: 29270329; PMCID: PMC5734098.
      View in: PubMed   Mentions: 11  
    48. The Challenges of Nutritional Assessment in Cirrhosis. Curr Nutr Rep. 2017 Sep; 6(3):274-280. Molfino A, Johnson S, Medici V. PMID: 29201536; PMCID: PMC5703218.
      View in: PubMed   Mentions: 7     Fields:    
    49. DNA methylation alterations in Alzheimer's disease. Environ Epigenet. 2017 May; 3(2):dvx008. Yokoyama AS, Rutledge JC, Medici V. PMID: 29492310; PMCID: PMC5804548.
      View in: PubMed   Mentions: 14  
    50. Role of cardiotrophin-1 in the regulation of metabolic circadian rhythms and adipose core clock genes in mice and characterization of 24-h circulating CT-1 profiles in normal-weight and overweight/obese subjects. FASEB J. 2017 04; 31(4):1639-1649. López-Yoldi M, Stanhope KL, Garaulet M, Chen XG, Marcos-Gómez B, Carrasco-Benso MP, Santa Maria EM, Escoté X, Lee V, Nunez MV, Medici V, Martínez-Ansó E, Sáinz N, Huerta AE, Laiglesia LM, Prieto J, Martínez JA, Bustos M, Havel PJ, Moreno-Aliaga MJ. PMID: 28096235; PMCID: PMC5349803.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    51. Genetic and environmental modifiers of Wilson disease. Handb Clin Neurol. 2017; 142:35-41. Medici V, Weiss KH. PMID: 28433108.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    52. Animal models of Wilson disease. Handb Clin Neurol. 2017; 142:57-70. Medici V, Huster D. PMID: 28433110.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    53. Malnutrition and Nutritional Support in Alcoholic Liver Disease: a Review. Curr Gastroenterol Rep. 2016 Dec; 18(12):65. Chao A, Waitzberg D, de Jesus RP, Bueno AA, Kha V, Allen K, Kappus M, Medici V. PMID: 27787787.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    54. Erratum to: Sarcopenia in Patients with Chronic Liver Disease: Can It Be Altered by Diet and Exercise? Curr Gastroenterol Rep. 2016 Nov; 18(11):57. Kappus MR, Saire Mendoza M, Nguyen D, Medici V, McClave SA. PMID: 27641726.
      View in: PubMed   Mentions:    Fields:    
    55. Nutritional Strategies in the Management of Adult Patients with Inflammatory Bowel Disease: Dietary Considerations from Active Disease to Disease Remission. Curr Gastroenterol Rep. 2016 Oct; 18(10):55. Nguyen DL, Limketkai B, Medici V, Saire Mendoza M, Palmer L, Bechtold M. PMID: 27637649.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    56. Wilson Disease: Epigenetic effects of choline supplementation on phenotype and clinical course in a mouse model. Epigenetics. 2016 Nov; 11(11):804-818. Medici V, Kieffer DA, Shibata NM, Chima H, Kim K, Canovas A, Medrano JF, Islas-Trejo AD, Kharbanda KK, Olson K, Su RJ, Islam MS, Syed R, Keen CL, Miller AY, Rutledge JC, Halsted CH, LaSalle JM. PMID: 27611852; PMCID: PMC5221658.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    57. Sarcopenia in Patients with Chronic Liver Disease: Can It Be Altered by Diet and Exercise? Curr Gastroenterol Rep. 2016 Aug; 18(8):43. Kappus MR, Mendoza MS, Nguyen D, Medici V, McClave SA. PMID: 27372291.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    58. Different parvalbumin and GABA expression in human epileptogenic focal cortical dysplasia. Epilepsia. 2016 07; 57(7):1109-19. Medici V, Rossini L, Deleo F, Tringali G, Tassi L, Cardinale F, Bramerio M, de Curtis M, Garbelli R, Spreafico R. PMID: 27173597.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    59. Effects of Nonpurified and Choline Supplemented or Nonsupplemented Purified Diets on Hepatic Steatosis and Methionine Metabolism in C3H Mice. Metab Syndr Relat Disord. 2016 May; 14(4):202-9. Syed R, Shibata NM, Kharbanda KK, Su RJ, Olson K, Yokoyama A, Rutledge JC, Chmiel KJ, Kim K, Halsted CH, Medici V. PMID: 26881897; PMCID: PMC4841906.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    60. Common Medications Which Lead to Unintended Alterations in Weight Gain or Organ Lipotoxicity. Curr Gastroenterol Rep. 2016 Jan; 18(1):2. Medici V, McClave SA, Miller KR. PMID: 26700070.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    61. Chapter 8 Vitamin B Regulation of Alcoholic Liver Disease. . 2016 Jan 1; 95-106. Halsted HC, Medici MV. .
      View in: Publisher Site   Mentions:
    62. Type II focal cortical dysplasia: Ex vivo 7T magnetic resonance imaging abnormalities and histopathological comparisons. Ann Neurol. 2016 Jan; 79(1):42-58. Zucca I, Milesi G, Medici V, Tassi L, Didato G, Cardinale F, Tringali G, Colombo N, Bramerio M, D'Incerti L, Freri E, Morbin M, Fugnanesi V, Figini M, Spreafico R, Garbelli R. PMID: 26448158.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    63. Differential Responses of Plasma Adropin Concentrations To Dietary Glucose or Fructose Consumption In Humans. Sci Rep. 2015 Oct 05; 5:14691. Butler AA, St-Onge MP, Siebert EA, Medici V, Stanhope KL, Havel PJ. PMID: 26435060; PMCID: PMC4592955.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    64. Should We Stop Using Gastric Residual Volumes?. Current Nutrition Reports. 2015 Sep 1; 4(3):236-241. Diamond DS, Medici MV, Rice RT, Miller MK. .
      View in: Publisher Site   Mentions:
    65. A dose-response study of consuming high-fructose corn syrup-sweetened beverages on lipid/lipoprotein risk factors for cardiovascular disease in young adults. Am J Clin Nutr. 2015 Jun; 101(6):1144-54. Stanhope KL, Medici V, Bremer AA, Lee V, Lam HD, Nunez MV, Chen GX, Keim NL, Havel PJ. PMID: 25904601; PMCID: PMC4441807.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansCTClinical Trials
    66. Excessive Sugar Consumption May Be a Difficult Habit to Break: A View From the Brain and Body. J Clin Endocrinol Metab. 2015 Jun; 100(6):2239-47. Tryon MS, Stanhope KL, Epel ES, Mason AE, Brown R, Medici V, Havel PJ, Laugero KD. PMID: 25879513; PMCID: PMC4454811.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    67. Ethnic differences in presentation and severity of alcoholic liver disease. Alcohol Clin Exp Res. 2015 Mar; 39(3):566-574. Levy R, Catana AM, Durbin-Johnson B, Halsted CH, Medici V. PMID: 25702770; PMCID: PMC4348235.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    68. Diagnosis of alcoholic liver disease. World J Gastroenterol. 2014 Sep 07; 20(33):11684-99. Torruellas C, French SW, Medici V. PMID: 25206273; PMCID: PMC4155359.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    69. Characterization of timed changes in hepatic copper concentrations, methionine metabolism, gene expression, and global DNA methylation in the Jackson toxic milk mouse model of Wilson disease. Int J Mol Sci. 2014 May 07; 15(5):8004-23. Le A, Shibata NM, French SW, Kim K, Kharbanda KK, Islam MS, LaSalle JM, Halsted CH, Keen CL, Medici V. PMID: 24810691; PMCID: PMC4057715.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    70. Layer-specific gene expression in epileptogenic type II focal cortical dysplasia: normal-looking neurons reveal the presence of a hidden laminar organization. Acta Neuropathol Commun. 2014 Apr 15; 2:45. Rossini L, Medici V, Tassi L, Cardinale F, Tringali G, Bramerio M, Villani F, Spreafico R, Garbelli R. PMID: 24735483; PMCID: PMC4023625.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    71. Methylation and gene expression responses to ethanol feeding and betaine supplementation in the cystathionine beta synthase-deficient mouse. Alcohol Clin Exp Res. 2014 Jun; 38(6):1540-9. Medici V, Schroeder DI, Woods R, LaSalle JM, Geng Y, Shibata NM, Peerson J, Hodzic E, Dayal S, Tsukamoto H, Kharbanda KK, Tillman B, French SW, Halsted CH. PMID: 24730561; PMCID: PMC4047166.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    72. Maternal choline modifies fetal liver copper, gene expression, DNA methylation, and neonatal growth in the tx-j mouse model of Wilson disease. Epigenetics. 2014 Feb; 9(2):286-96. Medici V, Shibata NM, Kharbanda KK, Islam MS, Keen CL, Kim K, Tillman B, French SW, Halsted CH, LaSalle JM. PMID: 24220304; PMCID: PMC3962539.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    73. Alcoholic liver disease patients treated with S-adenosyl-L-methionine: an in-depth look at liver morphologic data comparing pre and post treatment liver biopsies. Exp Mol Pathol. 2013 Oct; 95(2):187-91. Le MD, Enbom E, Traum PK, Medici V, Halsted CH, French SW. PMID: 23886644; PMCID: PMC3857393.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    74. Wilson's disease: changes in methionine metabolism and inflammation affect global DNA methylation in early liver disease. Hepatology. 2013 Feb; 57(2):555-65. Medici V, Shibata NM, Kharbanda KK, LaSalle JM, Woods R, Liu S, Engelberg JA, Devaraj S, Török NJ, Jiang JX, Havel PJ, Lönnerdal B, Kim K, Halsted CH. PMID: 22945834; PMCID: PMC3566330.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    75. Folate, alcohol, and liver disease. Mol Nutr Food Res. 2013 Apr; 57(4):596-606. Medici V, Halsted CH. PMID: 23136133; PMCID: PMC3736728.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    76. The evolving scenario of copper and fatty liver. Metab Syndr Relat Disord. 2013 Feb; 11(1):4-6. Medici V. PMID: 23127162.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    77. Blurring in patients with temporal lobe epilepsy: clinical, high-field imaging and ultrastructural study. Brain. 2012 Aug; 135(Pt 8):2337-49. Garbelli R, Milesi G, Medici V, Villani F, Didato G, Deleo F, D'Incerti L, Morbin M, Mazzoleni G, Giovagnoli AR, Parente A, Zucca I, Mastropietro A, Spreafico R. PMID: 22734123.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    78. Liver transplantation for Wilson disease. World J Hepatol. 2012 Jan 27; 4(1):5-10. Catana AM, Medici V. PMID: 22312450; PMCID: PMC3272077.
      View in: PubMed   Mentions: 14  
    79. S-adenosyl-L-methionine treatment for alcoholic liver disease: a double-blinded, randomized, placebo-controlled trial. Alcohol Clin Exp Res. 2011 Nov; 35(11):1960-5. Medici V, Virata MC, Peerson JM, Stabler SP, French SW, Gregory JF, Albanese A, Bowlus CL, Devaraj S, Panacek EA, Richards JR, Halsted CH. PMID: 22044287; PMCID: PMC3315189.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    80. Antioxidative potential of a combined therapy of anti TNFα and Zn acetate in experimental colitis. World J Gastroenterol. 2011 Sep 28; 17(36):4099-103. Barollo M, Medici V, D'Incà R, Banerjee A, Ingravallo G, Scarpa M, Patak S, Ruffolo C, Cardin R, Sturniolo GC. PMID: 22039323; PMCID: PMC3203360.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    81. Vitamin-dependent methionine metabolism and alcoholic liver disease. Adv Nutr. 2011 Sep; 2(5):421-7. Halsted CH, Medici V. PMID: 22332083; PMCID: PMC3183592.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimals
    82. Aberrant hepatic methionine metabolism and gene methylation in the pathogenesis and treatment of alcoholic steatohepatitis. Int J Hepatol. 2012; 2012:959746. Halsted CH, Medici V. PMID: 22007317; PMCID: PMC3168767.
      View in: PubMed   Mentions: 12  
    83. Consumption of fructose and high fructose corn syrup increase postprandial triglycerides, LDL-cholesterol, and apolipoprotein-B in young men and women. J Clin Endocrinol Metab. 2011 Oct; 96(10):E1596-605. Stanhope KL, Bremer AA, Medici V, Nakajima K, Ito Y, Nakano T, Chen G, Fong TH, Lee V, Menorca RI, Keim NL, Havel PJ. PMID: 21849529; PMCID: PMC3200248.
      View in: PubMed   Mentions: 103     Fields:    Translation:Humans
    84. Aquaporin 4 expression in control and epileptic human cerebral cortex. Brain Res. 2011 Jan 07; 1367:330-9. Medici V, Frassoni C, Tassi L, Spreafico R, Garbelli R. PMID: 20934410.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    85. Impaired homocysteine transsulfuration is an indicator of alcoholic liver disease. J Hepatol. 2010 Sep; 53(3):551-7. Medici V, Peerson JM, Stabler SP, French SW, Gregory JF, Virata MC, Albanese A, Bowlus CL, Devaraj S, Panacek EA, Rahim N, Richards JR, Rossaro L, Halsted CH. PMID: 20561703; PMCID: PMC2923260.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    86. Increased soluble leptin receptor levels in morbidly obese patients with insulin resistance and nonalcoholic fatty liver disease. Obesity (Silver Spring). 2010 Dec; 18(12):2268-73. Medici V, Ali MR, Seo S, Aoki CA, Rossaro L, Kim K, Fuller WD, Vidovszky TJ, Smith W, Jiang JX, Maganti K, Havel PJ, Kamboj A, Ramsamooj R, Török NJ. PMID: 20448542; PMCID: PMC4820322.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    87. Wilson disease: histopathological correlations with treatment on follow-up liver biopsies. World J Gastroenterol. 2010 Mar 28; 16(12):1487-94. Cope-Yokoyama S, Finegold MJ, Sturniolo GC, Kim K, Mescoli C, Rugge M, Medici V. PMID: 20333789; PMCID: PMC2846254.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    88. Epigenetic regulation of hepatic endoplasmic reticulum stress pathways in the ethanol-fed cystathionine beta synthase-deficient mouse. Hepatology. 2010 Mar; 51(3):932-41. Esfandiari F, Medici V, Wong DH, Jose S, Dolatshahi M, Quinlivan E, Dayal S, Lentz SR, Tsukamoto H, Zhang YH, French SW, Halsted CH. PMID: 19957376; PMCID: PMC2898175.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    89. METALLOTHIONEINS AND LIVER DISEASES. . 2008 Oct 1; 289-316. Oliva OL, D'Incà DR, Medici MV, Sturniolo SG. .
      View in: Publisher Site   Mentions:
    90. The utility of the model for end-stage liver disease score: a reliable guide for liver transplant candidacy and, for select patients, simultaneous hospice referral. Liver Transpl. 2008 Aug; 14(8):1100-6. Medici V, Rossaro L, Wegelin JA, Kamboj A, Nakai J, Fisher K, Meyers FJ. PMID: 18668666.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    91. Tetrathiomolybdate, a copper chelator for the treatment of Wilson disease, pulmonary fibrosis and other indications. IDrugs. 2008 Aug; 11(8):592-606. Medici V, Sturniolo GC. PMID: 18683094.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    92. Heterogeneous expression of SNAP-25 in rat and human brain. J Comp Neurol. 2008 Jan 20; 506(3):373-86. Garbelli R, Inverardi F, Medici V, Amadeo A, Verderio C, Matteoli M, Frassoni C. PMID: 18041776.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    93. Fluid retention in cirrhosis: pathophysiology and management. QJM. 2008 Feb; 101(2):71-85. Kashani A, Landaverde C, Medici V, Rossaro L. PMID: 18184668.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    94. Effect of penicillamine and zinc on iron metabolism in Wilson's disease. Scand J Gastroenterol. 2007 Dec; 42(12):1495-500. Medici V, Di Leo V, Lamboglia F, Bowlus CL, Tseng SC, D'Incà R, Irato P, Burra P, Martines D, Sturniolo GC. PMID: 17994470.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    95. M-30 and 4HNE are sequestered in different aggresomes in the same hepatocytes. Exp Mol Pathol. 2007 Dec; 83(3):296-300. Amidi F, French BA, Chung D, Halsted CH, Medici V, French SW. PMID: 17963745; PMCID: PMC2148495.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    96. Interaction between rifaximin and dietary fibre in patients with diverticular disease. Aliment Pharmacol Ther. 2007 Apr 01; 25(7):771-9. D'Incà R, Pomerri F, Vettorato MG, Dal Pont E, Di Leo V, Ferronato A, Medici V, Sturniolo GC. PMID: 17373915.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    97. Wilson disease--a practical approach to diagnosis, treatment and follow-up. Dig Liver Dis. 2007 Jul; 39(7):601-9. Medici V, Rossaro L, Sturniolo GC. PMID: 17382611.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    98. Innate and Adaptive Immune Responses to Bacterial and Parasite Infections. . 2007 Jan 1; 153-162. Medici MV, Rossaro RL, Balasubramanian BS, Cohen CS. .
      View in: Publisher Site   Mentions:
    99. Adverse reaction after tetrathiomolybdate treatment for Wilson's disease: a case report. Mov Disord. 2006 Nov; 21(11):2030-2. Medici V, Trevisan CP, Bigotto MA, D'Incà R, Martines D, Dal Pont E, Sturniolo GC. PMID: 16991142.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    100. Diagnosis and management of Wilson's disease: results of a single center experience. J Clin Gastroenterol. 2006 Nov-Dec; 40(10):936-41. Medici V, Trevisan CP, D'Incà R, Barollo M, Zancan L, Fagiuoli S, Martines D, Irato P, Sturniolo GC. PMID: 17063115.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    101. Extreme heterogeneity in CARD15 and DLG5 Crohn disease-associated polymorphisms between German and Norwegian populations. Eur J Hum Genet. 2006 Apr; 14(4):459-68. Medici V, Mascheretti S, Croucher PJ, Stoll M, Hampe J, Grebe J, Sturniolo GC, Solberg C, Jahnsen J, Moum B, Schreiber S, Vatn MH. PMID: 16493449.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    102. Liver transplantation for Wilson's disease: The burden of neurological and psychiatric disorders. Liver Transpl. 2005 Sep; 11(9):1056-63. Medici V, Mirante VG, Fassati LR, Pompili M, Forti D, Del Gaudio M, Trevisan CP, Cillo U, Sturniolo GC, Fagiuoli S, Monotematica AISF 2000 OLT Study Group. PMID: 16123950.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    103. Efficacy of zinc supplementation in preventing acute hepatitis in Long-Evans Cinnamon rats. Liver Int. 2005 Aug; 25(4):888-95. Medici V, Sturniolo GC, Santon A, D'Incà R, Bortolami M, Cardin R, Basso D, Albergoni V, Irato P. PMID: 15998441.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    104. Effects of iron manipulation on trace elements level in a model of colitis in rats. World J Gastroenterol. 2005 Jul 28; 11(28):4396-9. Barollo M, D'Inca R, Scarpa M, Medici V, Cardin R, Bortolami M, Ruffolo C, Angriman I, Sturniolo GC. PMID: 16038040; PMCID: PMC4434668.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    105. Differential modulation of p38 mitogen activated protein kinase and STAT3 signalling pathways by infliximab and etanercept in intestinal T cells from patients with Crohn's disease. Gut. 2005 Feb; 54(2):314-5; author reply 316-6. Rosenstiel P, Agnholt J, Kelsen J, Medici V, Waetzig GH, Seegert D, Schreiber S. PMID: 15647208; PMCID: PMC1774837.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    106. Prognosis of severe attacks in ulcerative colitis: effect of intensive medical treatment. Dig Liver Dis. 2004 Jul; 36(7):461-6. Benazzato L, D'Incà R, Grigoletto F, Perissinotto E, Medici V, Angriman I, Sturniolo GC. PMID: 15285525.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    107. Effects of iron deprivation or chelation on DNA damage in experimental colitis. Int J Colorectal Dis. 2004 Sep; 19(5):461-6. Barollo M, D'Incà R, Scarpa M, Medici V, Cardin R, Fries W, Angriman I, Sturniolo GC. PMID: 15067556.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    108. Effect and possible role of Zn treatment in LEC rats, an animal model of Wilson's disease. Biochim Biophys Acta. 2003 Jan 20; 1637(1):91-7. Santon A, Irato P, Medici V, D'Incà R, Albergoni V, Sturniolo GC. PMID: 12527412.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    109. Metallothionein and antioxidant enzymes in Long-Evans Cinnamon rats treated with zinc. Arch Toxicol. 2002 Sep; 76(9):509-16. Medici V, Santon A, Sturniolo GC, D'Incà R, Giannetto S, Albergoni V, Irato P. PMID: 12242608.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    110. Interactions between Zn and Cu in LEC rats, an animal model of Wilson's disease. Histochem Cell Biol. 2002 Mar; 117(3):275-81. Santon A, Giannetto S, Sturniolo GC, Medici V, D'Incà R, Irato P, Albergoni V. PMID: 11914925.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
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