Roy Ben-Shalom

Title(s)Assistant Professor, Neurology
SchoolSchool of Medicine
Address2805 50th Street #2419
CA 94710
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Complex biophysical changes and reduced neuronal firing in an SCN8A variant associated with developmental delay and epilepsy. Biochim Biophys Acta Mol Basis Dis. 2024 Mar 20; 1870(5):167127. Quinn S, Zhang N, Fenton TA, Brusel M, Muruganandam P, Peleg Y, Giladi M, Haitin Y, Lerche H, Bassan H, Liu Y, Ben-Shalom R, Rubinstein M. PMID: 38519006.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. Hyperexcitability and translational phenotypes in a preclinical mouse model of SYNGAP1-Related Intellectual Disability. Res Sq. 2024 Mar 19. Fenton TA, Haouchine OY, Hallam EL, Smith EM, Jackson KC, Rahbarian D, Canales C, Adhikari A, Nord AS, Ben-Shalom R, Silverman JL. PMID: 38562838; PMCID: PMC10984035.
      View in: PubMed   Mentions:
    3. Hyperexcitability and translational phenotypes in a preclinical model of SYNGAP1 mutations. Res Sq. 2023 Sep 13. Silverman JL, Fenton T, Haouchine O, Hallam E, Smith E, Jackson K, Rahbarian D, Canales C, Adhikari A, Nord A, Ben-Shalom R. PMID: 37790402; PMCID: PMC10543290.
      View in: PubMed   Mentions:
    4. Hyperexcitability and translational phenotypes in a preclinical model of SYNGAP1 mutations. bioRxiv. 2023 Jul 26. Fenton TA, Haouchine OY, Hallam EL, Smith EM, Jackson KC, Rahbarian D, Canales C, Adhikari A, Nord AS, Ben-Shalom R, Silverman JL. PMID: 37546838; PMCID: PMC10402099.
      View in: PubMed   Mentions:
    5. Cellular and behavioral effects of altered NaV1.2 sodium channel ion permeability in Scn2aK1422E mice. Hum Mol Genet. 2022 08 25; 31(17):2964-2988. Echevarria-Cooper DM, Hawkins NA, Misra SN, Huffman AM, Thaxton T, Thompson CH, Ben-Shalom R, Nelson AD, Lipkin AM, George AL, Bender KJ, Kearney JA. PMID: 35417922; PMCID: PMC9433730.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    6. Scaling and Benchmarking an Evolutionary Algorithm for Constructing Biophysical Neuronal Models. Front Neuroinform. 2022; 16:882552. Ladd A, Kim KG, Balewski J, Bouchard K, Ben-Shalom R. PMID: 35784184; PMCID: PMC9248031.
      View in: PubMed   Mentions:
    7. NeuroGPU: Accelerating multi-compartment, biophysically detailed neuron simulations on GPUs. J Neurosci Methods. 2022 Jan 15; 366:109400. Ben-Shalom R, Ladd A, Artherya NS, Cross C, Kim KG, Sanghevi H, Korngreen A, Bouchard KE, Bender KJ. PMID: 34728257; PMCID: PMC9887806.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    8. Paradoxical hyperexcitability from NaV1.2 sodium channel loss in neocortical pyramidal cells. Cell Rep. 2021 08 03; 36(5):109483. Spratt PWE, Alexander RPD, Ben-Shalom R, Sahagun A, Kyoung H, Keeshen CM, Sanders SJ, Bender KJ. PMID: 34348157; PMCID: PMC8719649.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    9. Alternative splicing potentiates dysfunction of early-onset epileptic encephalopathy SCN2A variants. J Gen Physiol. 2020 03 02; 152(3). Thompson CH, Ben-Shalom R, Bender KJ, George AL. PMID: 31995133; PMCID: PMC7054859.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    10. The Autism-Associated Gene Scn2a Contributes to Dendritic Excitability and Synaptic Function in the Prefrontal Cortex. Neuron. 2019 08 21; 103(4):673-685.e5. Spratt PWE, Ben-Shalom R, Keeshen CM, Burke KJ, Clarkson RL, Sanders SJ, Bender KJ. PMID: 31230762; PMCID: PMC7935470.
      View in: PubMed   Mentions: 78     Fields:    Translation:AnimalsCells
    11. Serotonin enhances excitability and gamma frequency temporal integration in mouse prefrontal fast-spiking interneurons. Elife. 2017 12 05; 6. Athilingam JC, Ben-Shalom R, Keeshen CM, Sohal VS, Bender KJ. PMID: 29206101; PMCID: PMC5746342.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    12. Opposing Effects on NaV1.2 Function Underlie Differences Between SCN2A Variants Observed in Individuals With Autism Spectrum Disorder or Infantile Seizures. Biol Psychiatry. 2017 08 01; 82(3):224-232. Ben-Shalom R, Keeshen CM, Berrios KN, An JY, Sanders SJ, Bender KJ. PMID: 28256214; PMCID: PMC5796785.
      View in: PubMed   Mentions: 103     Fields:    Translation:HumansCells
    13. β-Arrestin-Dependent Dopaminergic Regulation of Calcium Channel Activity in the Axon Initial Segment. Cell Rep. 2016 08 09; 16(6):1518-1526. Yang S, Ben-Shalom R, Ahn M, Liptak AT, van Rijn RM, Whistler JL, Bender KJ. PMID: 27452469; PMCID: PMC5074334.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    14. Accelerating compartmental modeling on a graphical processing unit. Front Neuroinform. 2013; 7:4. Ben-Shalom R, Liberman G, Korngreen A. PMID: 23508232; PMCID: PMC3600538.
      View in: PubMed   Mentions: 9  
    15. Optimizing ion channel models using a parallel genetic algorithm on graphical processors. J Neurosci Methods. 2012; 206(2):183-94. Ben-Shalom R, Aviv A, Razon B, Korngreen A. PMID: 22407006.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
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