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Jennifer Whistler

Title(s)Professor, Physiology and Membrane Biology
SchoolUniversity of California, Davis
AddressDavis Campus
CA 95616
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    Genetic Variation in the Neuropeptide S Receptor and Opioid Abuse Liability
    NIH/NIDA R21DA043816Sep 1, 2017 - Aug 31, 2019
    Role: Principal Investigator
    Molecular and circuit mechanisms of antipsychotics
    NIH/NIMH R01MH112729Apr 10, 2017 - Feb 28, 2022
    Role: Co-Principal Investigator
    Dopamine receptor trafficking in drug sensitization and behavioral flexibility
    NIH/NIDA R01DA037963Sep 15, 2015 - Jun 30, 2020
    Role: Principal Investigator
    Neuropeptide S receptors in ethanol abuse and anxiety
    NIH/NIAAA R21AA023231Sep 10, 2015 - Aug 31, 2018
    Role: Principal Investigator
    Receptor trafficking profiles of clinically important dopaminergic drugs
    NIH/NIMH R21MH096058Mar 1, 2012 - Feb 28, 2014
    Role: Principal Investigator
    Selectively targeting delta opioid receptor subtypes to control drinking behavior
    NIH/NIAAA R01AA020401Aug 1, 2011 - Jun 30, 2018
    Role: Principal Investigator
    Selectively Targeting Opioid Receptor Heterodimers
    NIH/NIDA R21DA031574Feb 15, 2011 - Jun 30, 2013
    Role: Principal Investigator
    Role of opioid receptor trafficking in tolerance and dependence
    NIH/NIDA R01DA019958May 1, 2007 - Mar 31, 2014
    Role: Principal Investigator
    GASP and Trafficking of the Dopamine Receptors
    NIH/NIMH R01MH068442Jul 1, 2003 - Apr 30, 2009
    Role: Principal Investigator
    Trafficking and signaling of opioid receptor subtypes and heterodimers
    NIH/NIDA R01DA015232Apr 1, 2002 - Jul 31, 2011
    Role: Principal Investigator
    REGULATION OF OPIOID RECEPTOR FUNCTION
    NIH/NIDA F32DA005844Mar 25, 1998
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. TGF-ß Signaling in Dopaminergic Neurons Regulates Dendritic Growth, Excitatory-Inhibitory Synaptic Balance, and Reversal Learning. Cell Rep. 2016 12 20; 17(12):3233-3245. Luo SX, Timbang L, Kim JI, Shang Y, Sandoval K, Tang AA, Whistler JL, Ding JB, Huang EJ. PMID: 28009292.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    2. Identification of the First Marine-Derived Opioid Receptor "Balanced" Agonist with a Signaling Profile That Resembles the Endorphins. ACS Chem Neurosci. 2017 03 15; 8(3):473-485. Johnson TA, Milan-Lobo L, Che T, Ferwerda M, Lambu E, McIntosh NL, Li F, He L, Lorig-Roach N, Crews P, Whistler JL. PMID: 27744679.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    3. Identification of the Kappa-Opioid Receptor as a Therapeutic Target for Oligodendrocyte Remyelination. J Neurosci. 2016 07 27; 36(30):7925-35. Mei F, Mayoral SR, Nobuta H, Wang F, Desponts C, Lorrain DS, Xiao L, Green AJ, Rowitch D, Whistler J, Chan JR. PMID: 27466337.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    4. ß-Arrestin-Dependent Dopaminergic Regulation of Calcium Channel Activity in the Axon Initial Segment. Cell Rep. 2016 08 09; 16(6):1518-1526. Yang S, Ben-Shalom R, Ahn M, Liptak AT, van Rijn RM, Whistler JL, Bender KJ. PMID: 27452469.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    5. Dynorphin Controls the Gain of an Amygdalar Anxiety Circuit. Cell Rep. 2016 Mar 29; 14(12):2774-83. Crowley NA, Bloodgood DW, Hardaway JA, Kendra AM, McCall JG, Al-Hasani R, McCall NM, Yu W, Schools ZL, Krashes MJ, Lowell BB, Whistler JL, Bruchas MR, Kash TL. PMID: 26997280.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    6. Trafficking of the D2 Dopamine Receptor Promotes Drug-Induced Changes in Neuronal and Behavioral Plasticity. . 2014 Jan 1; 97-98. Pia Tschische, Anuradha Madhavan, Jegath Athiligam, Laura Milan-Lobo, Dawn Thompson, Linda Wilbrecht, Jennifer L. Whistler. .
      View in: Publisher Site   Mentions:
    7. Real-time trafficking and signaling of the glucagon-like peptide-1 receptor. Mol Cell Endocrinol. 2014 Feb 15; 382(2):938-49. Roed SN, Wismann P, Underwood CR, Kulahin N, Iversen H, Cappelen KA, Schäffer L, Lehtonen J, Hecksher-Soerensen J, Secher A, Mathiesen JM, Bräuner-Osborne H, Whistler JL, Knudsen SM, Waldhoer M. PMID: 24275181.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    8. Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism. Cell. 2013 Aug 29; 154(5):1085-1099. He C, Wei Y, Sun K, Li B, Dong X, Zou Z, Liu Y, Kinch LN, Khan S, Sinha S, Xavier RJ, Grishin NV, Xiao G, Eskelinen EL, Scherer PE, Whistler JL, Levine B. PMID: 23954414.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    9. Loss of D2 dopamine receptor function modulates cocaine-induced glutamatergic synaptic potentiation in the ventral tegmental area. J Neurosci. 2013 Jul 24; 33(30):12329-36. Madhavan A, Argilli E, Bonci A, Whistler JL. PMID: 23884939.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    10. Pharmacological traits of delta opioid receptors: pitfalls or opportunities? Psychopharmacology (Berl). 2013 Jul; 228(1):1-18. van Rijn RM, Defriel JN, Whistler JL. PMID: 23649885.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    11. Anti-analgesic effect of the mu/delta opioid receptor heteromer revealed by ligand-biased antagonism. PLoS One. 2013; 8(3):e58362. Milan-Lobo L, Enquist J, van Rijn RM, Whistler JL. PMID: 23554887.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    12. Intestinal epithelial cell-derived µ-opioid signaling protects against ischemia reperfusion injury through PI3K signaling. Am J Pathol. 2013 Mar; 182(3):776-85. Goldsmith JR, Perez-Chanona E, Yadav PN, Whistler J, Roth B, Jobin C. PMID: 23291213.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    13. A FLIPR assay for evaluating agonists and antagonists of GPCR heterodimers. Methods Mol Biol. 2013; 995:43-54. Harvey JH, van Rijn RM, Whistler JL. PMID: 23494371.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    14. Novel screening assay for the selective detection of G-protein-coupled receptor heteromer signaling. J Pharmacol Exp Ther. 2013 Jan; 344(1):179-88. van Rijn RM, Harvey JH, Brissett DI, DeFriel JN, Whistler JL. PMID: 23097213.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    15. Tuned-Affinity Bivalent Ligands for the Characterization of Opioid Receptor Heteromers. ACS Med Chem Lett. 2012 Aug 09; 3(8):640-644. Harvey JH, Long DH, England PM, Whistler JL. PMID: 23585918.
      View in: PubMed   Mentions:
    16. Chronic ethanol potentiates the effect of neuropeptide s in the basolateral amygdala and shows increased anxiolytic and anti-depressive effects. Neuropsychopharmacology. 2012 Oct; 37(11):2436-45. Enquist J, Ferwerda M, Madhavan A, Hok D, Whistler JL. PMID: 22739468.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    17. The chemoselective reactions of tyrosine-containing G-protein-coupled receptor peptides with [Cp*Rh(H2O)3](OTf)2, including 2D NMR structures and the biological consequences. J Am Chem Soc. 2012 Jun 27; 134(25):10321-4. Albada HB, Wieberneit F, Dijkgraaf I, Harvey JH, Whistler JL, Stoll R, Metzler-Nolte N, Fish RH. PMID: 22671299.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    18. The GPCR-associated sorting protein 1 regulates ligand-induced down-regulation of GPR55. Br J Pharmacol. 2012 Apr; 165(8):2611-9. Kargl J, Balenga NA, Platzer W, Martini L, Whistler JL, Waldhoer M. PMID: 21718301.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    19. PGH1, the precursor for the anti-inflammatory prostaglandins of the 1-series, is a potent activator of the pro-inflammatory receptor CRTH2/DP2. PLoS One. 2012; 7(3):e33329. Schröder R, Xue L, Konya V, Martini L, Kampitsch N, Whistler JL, Ulven T, Heinemann A, Pettipher R, Kostenis E. PMID: 22442685.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCellsCTClinical Trials
    20. Examining the role of mu opioid receptor endocytosis in the beneficial and side-effects of prolonged opioid use: from a symposium on new concepts in mu-opioid pharmacology. Drug Alcohol Depend. 2012 Mar 01; 121(3):189-204. Whistler JL. PMID: 22226706.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    21. Contribution of mu and delta opioid receptors to the pharmacological profile of kappa opioid receptor subtypes. Eur J Pain. 2012 Mar; 16(3):327-37. Brissett DI, Whistler JL, van Rijn RM. PMID: 22337177.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    22. Chronic methadone treatment shows a better cost/benefit ratio than chronic morphine in mice. J Pharmacol Exp Ther. 2012 Feb; 340(2):386-92. Enquist J, Ferwerda M, Milan-Lobo L, Whistler JL. PMID: 22062352.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    23. Development of a bivalent dopamine D2 receptor agonist. J Med Chem. 2011 Nov 24; 54(22):7911-9. Kühhorn J, Götz A, Hübner H, Thompson D, Whistler J, Gmeiner P. PMID: 21999579.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    24. Distinctive modulation of ethanol place preference by delta opioid receptor-selective agonists. Drug Alcohol Depend. 2012 Apr 01; 122(1-2):156-9. van Rijn RM, Brissett DI, Whistler JL. PMID: 22018601.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    25. Emergence of functional spinal delta opioid receptors after chronic ethanol exposure. Biol Psychiatry. 2012 Feb 01; 71(3):232-8. van Rijn RM, Brissett DI, Whistler JL. PMID: 21889123.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    26. Morphine-induced mu opioid receptor trafficking enhances reward yet prevents compulsive drug use. EMBO Mol Med. 2011 Jul; 3(7):385-97. Berger AC, Whistler JL. PMID: 21656686.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    27. Chronic ethanol consumption in rats produces opioid antinociceptive tolerance through inhibition of mu opioid receptor endocytosis. PLoS One. 2011; 6(5):e19372. He L, Whistler JL. PMID: 21602922.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    28. A novel knock-in mouse reveals mechanistically distinct forms of morphine tolerance. J Pharmacol Exp Ther. 2011 Aug; 338(2):633-40. Enquist J, Kim JA, Bartlett S, Ferwerda M, Whistler JL. PMID: 21562138.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    29. Trafficking properties of the D5 dopamine receptor. Traffic. 2011 May; 12(5):644-56. Thompson D, Whistler JL. PMID: 21348911.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    30. Heteromerization of the µ- and d-opioid receptors produces ligand-biased antagonism and alters µ-receptor trafficking. J Pharmacol Exp Ther. 2011 Jun; 337(3):868-75. Milan-Lobo L, Whistler JL. PMID: 21422164.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    31. Highly potent 5-aminotetrahydropyrazolopyridines: enantioselective dopamine D3 receptor binding, functional selectivity, and analysis of receptor-ligand interactions. J Med Chem. 2011 Apr 14; 54(7):2477-91. Tschammer N, Elsner J, Goetz A, Ehrlich K, Schuster S, Ruberg M, Kühhorn J, Thompson D, Whistler J, Hübner H, Gmeiner P. PMID: 21388142.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    32. Dopamine D(3) receptors are down-regulated following heterologous endocytosis by a specific interaction with G protein-coupled receptor-associated sorting protein-1. J Biol Chem. 2011 Jan 14; 286(2):1598-608. Thompson D, Whistler JL. PMID: 21030592.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    33. Opioid-Induced GABA potentiation after chronic morphine attenuates the rewarding effects of opioids in the ventral tegmental area. J Neurosci. 2010 Oct 20; 30(42):14029-35. Madhavan A, Bonci A, Whistler JL. PMID: 20962224.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    34. Dual efficacy of delta opioid receptor-selective ligands for ethanol drinking and anxiety. J Pharmacol Exp Ther. 2010 Oct; 335(1):133-9. van Rijn RM, Brissett DI, Whistler JL. PMID: 20605909.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    35. G protein-coupled receptor-associated sorting protein 1 regulates the postendocytic sorting of seven-transmembrane-spanning G protein-coupled receptors. Pharmacology. 2010; 86(1):22-9. Moser E, Kargl J, Whistler JL, Waldhoer M, Tschische P. PMID: 20693822.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    36. Altered ratio of D1 and D2 dopamine receptors in mouse striatum is associated with behavioral sensitization to cocaine. PLoS One. 2010 Jun 09; 5(6):e11038. Thompson D, Martini L, Whistler JL. PMID: 20543951.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    37. How to design an opioid drug that causes reduced tolerance and dependence. Ann Neurol. 2010 May; 67(5):559-69. Berger AC, Whistler JL. PMID: 20437553.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    38. The G-protein coupled receptor associated sorting protein GASP-1 regulates the signalling and trafficking of the viral chemokine receptor US28. Traffic. 2010 May; 11(5):660-74. Tschische P, Moser E, Thompson D, Vischer HF, Parzmair GP, Pommer V, Platzer W, Schwarzbraun T, Schaider H, Smit MJ, Martini L, Whistler JL, Waldhoer M. PMID: 20102549.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    39. An angiotensin II type 1 receptor activation switch patch revealed through evolutionary trace analysis. Biochem Pharmacol. 2010 Jul 01; 80(1):86-94. Bonde MM, Yao R, Ma JN, Madabushi S, Haunsø S, Burstein ES, Whistler JL, Sheikh SP, Lichtarge O, Hansen JL. PMID: 20227396.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    40. micro-Opioid receptor endocytosis prevents adaptations in ventral tegmental area GABA transmission induced during naloxone-precipitated morphine withdrawal. J Neurosci. 2010 Mar 03; 30(9):3276-86. Madhavan A, He L, Stuber GD, Bonci A, Whistler JL. PMID: 20203187.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    41. Differential regulation of behavioral tolerance to WIN55,212-2 by GASP1. Neuropsychopharmacology. 2010 May; 35(6):1363-73. Martini L, Thompson D, Kharazia V, Whistler JL. PMID: 20164830.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    42. GPR55 ligands promote receptor coupling to multiple signalling pathways. Br J Pharmacol. 2010 Jun; 160(3):604-14. Henstridge CM, Balenga NA, Schröder R, Kargl JK, Platzer W, Martini L, Arthur S, Penman J, Whistler JL, Kostenis E, Waldhoer M, Irving AJ. PMID: 20136841.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    43. Opioid-receptor-heteromer-specific trafficking and pharmacology. Curr Opin Pharmacol. 2010 Feb; 10(1):73-9. van Rijn RM, Whistler JL, Waldhoer M. PMID: 19846340.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    44. Biomarkers of morphine tolerance and dependence are prevented by morphine-induced endocytosis of a mutant mu-opioid receptor. FASEB J. 2009 Dec; 23(12):4327-34. He L, Kim JA, Whistler JL. PMID: 19679639.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    45. The delta(1) opioid receptor is a heterodimer that opposes the actions of the delta(2) receptor on alcohol intake. Biol Psychiatry. 2009 Oct 15; 66(8):777-84. van Rijn RM, Whistler JL. PMID: 19576572.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    46. Functional characterization of human variants of the mu-opioid receptor gene. Proc Natl Acad Sci U S A. 2009 Jun 30; 106(26):10811-6. Ravindranathan A, Joslyn G, Robertson M, Schuckit MA, Whistler JL, White RL. PMID: 19528663.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    47. Methadone antinociception is dependent on peripheral opioid receptors. J Pain. 2009 Apr; 10(4):369-79. He L, Kim J, Ou C, McFadden W, van Rijn RM, Whistler JL. PMID: 19327642.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    48. PKCepsilon regulates behavioral sensitivity, binding and tolerance to the CB1 receptor agonist WIN55,212-2. Neuropsychopharmacology. 2009 Jun; 34(7):1733-42. Wallace MJ, Newton PM, McMahon T, Connolly J, Huibers A, Whistler J, Messing RO. PMID: 19158669.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    49. The only way is up: preventing opioid tolerance by promoting cell surface expression of MOR-DOR heterodimers? Mol Interv. 2008 Dec; 8(6):277-80. van Rijn RM, Whistler JL. PMID: 19144899.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    50. The C-terminal tail of CRTH2 is a key molecular determinant that constrains Galphai and downstream signaling cascade activation. J Biol Chem. 2009 Jan 09; 284(2):1324-36. Schröder R, Merten N, Mathiesen JM, Martini L, Kruljac-Letunic A, Krop F, Blaukat A, Fang Y, Tran E, Ulven T, Drewke C, Whistler J, Pardo L, Gomeza J, Kostenis E. PMID: 19010788.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    51. Morphine-induced receptor endocytosis in a novel knockin mouse reduces tolerance and dependence. Curr Biol. 2008 Jan 22; 18(2):129-35. Kim JA, Bartlett S, He L, Nielsen CK, Chang AM, Kharazia V, Waldhoer M, Ou CJ, Taylor S, Ferwerda M, Cado D, Whistler JL. PMID: 18207746.
      View in: PubMed   Mentions: 45     Fields:    Translation:Animals
    52. The role of mu opioid receptor desensitization and endocytosis in morphine tolerance and dependence. Curr Opin Neurobiol. 2007 Oct; 17(5):556-64. Martini L, Whistler JL. PMID: 18068348.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansAnimalsCells
    53. Changes in G protein-coupled receptor sorting protein affinity regulate postendocytic targeting of G protein-coupled receptors. J Biol Chem. 2007 Oct 05; 282(40):29178-85. Thompson D, Pusch M, Whistler JL. PMID: 17635908.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    54. Acute amphetamine exposure selectively desensitizes kappa-opioid receptors in the nucleus accumbens. Neuropsychopharmacology. 2008 Mar; 33(4):892-900. Xia YF, He L, Whistler JL, Hjelmstad GO. PMID: 17551543.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    55. A molecular basis of analgesic tolerance to cannabinoids. J Neurosci. 2007 Apr 11; 27(15):4165-77. Tappe-Theodor A, Agarwal N, Katona I, Rubino T, Martini L, Swiercz J, Mackie K, Monyer H, Parolaro D, Whistler J, Kuner T, Kuner R. PMID: 17428994.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    56. Downregulation of mu opioid receptor by RNA interference in the ventral tegmental area reduces ethanol consumption in mice. Genes Brain Behav. 2007 Nov; 6(8):728-35. Lasek AW, Janak PH, He L, Whistler JL, Heberlein U. PMID: 17428267.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    57. The biochemical analysis of methadone modulation on morphine-induced tolerance and dependence in the rat brain. Pharmacology. 2007; 79(4):193-202. He L, Whistler JL. PMID: 17356311.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    58. Ligand-induced down-regulation of the cannabinoid 1 receptor is mediated by the G-protein-coupled receptor-associated sorting protein GASP1. FASEB J. 2007 Mar; 21(3):802-11. Martini L, Waldhoer M, Pusch M, Kharazia V, Fong J, Lee JH, Freissmuth C, Whistler JL. PMID: 17197383.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    59. Kinins promote B2 receptor endocytosis and delay constitutive B1 receptor endocytosis. Mol Pharmacol. 2007 Feb; 71(2):494-507. Enquist J, Skröder C, Whistler JL, Leeb-Lundberg LM. PMID: 17110500.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    60. Dopamine responsiveness is regulated by targeted sorting of D2 receptors. Proc Natl Acad Sci U S A. 2005 Aug 09; 102(32):11521-6. Bartlett SE, Enquist J, Hopf FW, Lee JH, Gladher F, Kharazia V, Waldhoer M, Mailliard WS, Armstrong R, Bonci A, Whistler JL. PMID: 16049099.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    61. An opiate cocktail that reduces morphine tolerance and dependence. Curr Biol. 2005 Jun 07; 15(11):1028-33. He L, Whistler JL. PMID: 15936273.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    62. A heterodimer-selective agonist shows in vivo relevance of G protein-coupled receptor dimers. Proc Natl Acad Sci U S A. 2005 Jun 21; 102(25):9050-5. Waldhoer M, Fong J, Jones RM, Lunzer MM, Sharma SK, Kostenis E, Portoghese PS, Whistler JL. PMID: 15932946.
      View in: PubMed   Mentions: 105     Fields:    Translation:HumansCells
    63. A highly conserved glycine within linker I and the extreme C terminus of G protein alpha subunits interact cooperatively in switching G protein-coupled receptor-to-effector specificity. J Pharmacol Exp Ther. 2005 Apr; 313(1):78-87. Kostenis E, Martini L, Ellis J, Waldhoer M, Heydorn A, Rosenkilde MM, Norregaard PK, Jorgensen R, Whistler JL, Milligan G. PMID: 15615862.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    64. A library of 7TM receptor C-terminal tails. Interactions with the proposed post-endocytic sorting proteins ERM-binding phosphoprotein 50 (EBP50), N-ethylmaleimide-sensitive factor (NSF), sorting nexin 1 (SNX1), and G protein-coupled receptor-associated sorting protein (GASP). J Biol Chem. 2004 Dec 24; 279(52):54291-303. Heydorn A, Søndergaard BP, Ersbøll B, Holst B, Nielsen FC, Haft CR, Whistler J, Schwartz TW. PMID: 15452121.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansCells
    65. Opioid receptors. Annu Rev Biochem. 2004; 73:953-90. Waldhoer M, Bartlett SE, Whistler JL. PMID: 15189164.
      View in: PubMed   Mentions: 148     Fields:    Translation:HumansAnimals
    66. The carboxyl terminus of human cytomegalovirus-encoded 7 transmembrane receptor US28 camouflages agonism by mediating constitutive endocytosis. J Biol Chem. 2003 May 23; 278(21):19473-82. Waldhoer M, Casarosa P, Rosenkilde MM, Smit MJ, Leurs R, Whistler JL, Schwartz TW. PMID: 12646575.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    67. Constitutive activation and endocytosis of the complement factor 5a receptor: evidence for multiple activated conformations of a G protein-coupled receptor. Traffic. 2002 Dec; 3(12):866-77. Whistler JL, Gerber BO, Meng EC, Baranski TJ, von Zastrow M, Bourne HR. PMID: 12453150.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    68. Modulation of postendocytic sorting of G protein-coupled receptors. Science. 2002 Jul 26; 297(5581):615-20. Whistler JL, Enquist J, Marley A, Fong J, Gladher F, Tsuruda P, Murray SR, Von Zastrow M. PMID: 12142540.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansAnimalsCells
    69. mu-Opioid receptors: Ligand-dependent activation of potassium conductance, desensitization, and internalization. J Neurosci. 2002 Jul 01; 22(13):5769-76. Alvarez VA, Arttamangkul S, Dang V, Salem A, Whistler JL, Von Zastrow M, Grandy DK, Williams JT. PMID: 12097530.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    70. The near-death experience of delta opioid receptors leads to new drug targets. Mol Interv. 2002 Jun; 2(3):134-6. Bartlett SE, Whistler JL. PMID: 14993372.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
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