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Aldrin V Gomes

Title(s)Professor, Neurobiology, Physiology and Behavior
SchoolUniversity of California, Davis
Phone530-752-3207
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    Collapse Research 
    Collapse Research Activities and Funding
    The Role of the Proteasome in Troponin related Cardiomyopathies
    NIH/NHLBI R01HL096819May 1, 2010 - Apr 30, 2015
    Role: Principal Investigator
    UC Davis MARC Scholar Program
    NIH/NIGMS T34GM083894Jun 1, 2008 - May 31, 2020
    Role: Principal Investigator
    UC Davis Biology Program
    NIH/NIGMS R25GM056765Feb 1, 1998 - May 31, 2019
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Mishra M, Tiwari S, Gunaseelan A, Li D, Hammock BD, Gomes AV. Improving the sensitivity of traditional Western blotting via Streptavidin containing Poly-horseradish peroxidase (PolyHRP). Electrophoresis. 2019 07; 40(12-13):1731-1739. PMID: 31021001.
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    2. Sander H, Wallace S, Plouse R, Tiwari S, Gomes AV. Ponceau S waste: Ponceau S staining for total protein normalization. Anal Biochem. 2019 Jun 15; 575:44-53. PMID: 30914243.
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    3. Hwang HV, Lin Y, Rebuffatti MN, Tran DT, Lee L, Gomes AV, Li CS, Knowlton AA. Impaired proteostasis in senescent vascular endothelial cells: a perspective on estrogen and oxidative stress in the aging vasculature. Am J Physiol Heart Circ Physiol. 2019 02 01; 316(2):H421-H429. PMID: 30499713.
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    4. Kazmierczak K, Liang J, Yuan CC, Yadav S, Sitbon YH, Walz K, Ma W, Irving TC, Cheah JX, Gomes AV, Szczesna-Cordary D. Slow-twitch skeletal muscle defects accompany cardiac dysfunction in transgenic mice with a mutation in the myosin regulatory light chain. FASEB J. 2019 03; 33(3):3152-3166. PMID: 30365366.
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    5. Gomes AV. Spatiotemporal Multi-Omics-Derived Atlas of Calcific Aortic Valve Disease. Circulation. 2018 07 24; 138(4):394-396. PMID: 30571374.
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    6. Yuan CC, Kazmierczak K, Liang J, Zhou Z, Yadav S, Gomes AV, Irving TC, Szczesna-Cordary D. Sarcomeric perturbations of myosin motors lead to dilated cardiomyopathy in genetically modified MYL2 mice. Proc Natl Acad Sci U S A. 2018 03 06; 115(10):E2338-E2347. PMID: 29463717.
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    7. Mishra M, Tiwari S, Gomes AV. Protein purification and analysis: next generation Western blotting techniques. Expert Rev Proteomics. 2017 11; 14(11):1037-1053. PMID: 28974114.
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    8. Inceoglu B, Bettaieb A, Haj FG, Gomes AV, Hammock BD. Modulation of mitochondrial dysfunction and endoplasmic reticulum stress are key mechanisms for the wide-ranging actions of epoxy fatty acids and soluble epoxide hydrolase inhibitors. Prostaglandins Other Lipid Mediat. 2017 Nov; 133:68-78. PMID: 28847566.
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    9. Yuan CC, Kazmierczak K, Liang J, Kanashiro-Takeuchi R, Irving TC, Gomes AV, Wang Y, Burghardt TP, Szczesna-Cordary D. Hypercontractile mutant of ventricular myosin essential light chain leads to disruption of sarcomeric structure and function and results in restrictive cardiomyopathy in mice. Cardiovasc Res. 2017 Aug 01; 113(10):1124-1136. PMID: 28371863.
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    10. Gilda JE, Gomes AV. Proteasome dysfunction in cardiomyopathies. J Physiol. 2017 06 15; 595(12):4051-4071. PMID: 28181243.
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    11. Wagner K, Gilda J, Yang J, Wan D, Morisseau C, Gomes AV, Hammock BD. Soluble epoxide hydrolase inhibition alleviates neuropathy in Akita (Ins2 Akita) mice. Behav Brain Res. 2017 05 30; 326:69-76. PMID: 28259677.
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    12. Nguyen S, Siu R, Dewey S, Cui Z, Gomes AV. Amino Acid Changes at Arginine 204 of Troponin I Result in Increased Calcium Sensitivity of Force Development. Front Physiol. 2016; 7:520. PMID: 27895589.
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    13. Carbonell T, Alva N, Sanchez-Nuño S, Dewey S, Gomes AV. Subnormothermic Perfusion in the Isolated Rat Liver Preserves the Antioxidant Glutathione and Enhances the Function of the Ubiquitin Proteasome System. Oxid Med Cell Longev. 2016; 2016:9324692. PMID: 27800122.
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    14. Ghosh R, Goswami SK, Feitoza LFBB, Hammock B, Gomes AV. Diclofenac induces proteasome and mitochondrial dysfunction in murine cardiomyocytes and hearts. Int J Cardiol. 2016 Nov 15; 223:923-935. PMID: 27589040.
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    15. Ghosh R, Hwang SM, Cui Z, Gilda JE, Gomes AV. Different effects of the nonsteroidal anti-inflammatory drugs meclofenamate sodium and naproxen sodium on proteasome activity in cardiac cells. J Mol Cell Cardiol. 2016 05; 94:131-144. PMID: 27049794.
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    16. Gilda JE, Lai X, Witzmann FA, Gomes AV. Delineation of Molecular Pathways Involved in Cardiomyopathies Caused by Troponin T Mutations. Mol Cell Proteomics. 2016 06; 15(6):1962-81. PMID: 27022107.
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    17. Gilda JE, Xu Q, Martinez ME, Nguyen ST, Chase PB, Gomes AV. The functional significance of the last 5 residues of the C-terminus of cardiac troponin I. Arch Biochem Biophys. 2016 07 01; 601:88-96. PMID: 26919894.
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    18. Landry M, Gomes AV. Antibodies: Half of samples fail protein-blot tests. Nature. 2016 Jan 07; 529(7584):25. PMID: 26738583.
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    19. Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Bánhegyi G, Bao H, Barbeau B, Barrachina MD, Barreiro E, Bartel B, Bartolomé A, Bassham DC, Bassi MT, Bast RC, Basu A, Batista MT, Batoko H, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beaulieu JF, Beck GR, Becker C, Beckham JD, Bédard PA, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, Bénard G, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernard A, Bernard M, Bernassola F, Bertolotti A, Bess AS, Besteiro S, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bianchi MW, Biard-Piechaczyk M, Billes V, Bincoletto C, Bingol B, Bird SW, Bitoun M, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Böckler S, Boes M, Boesze-Battaglia K, Boise LH, Bolino A, Boman A, Bonaldo P, Bordi M, Bosch J, Botana LM, Botti J, Bou G, Bouché M, Bouchecareilh M, Boucher MJ, Boulton ME, Bouret SG, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady N, Braga VM, Brancolini C, Braus GH, Bravo-San Pedro JM, Brennan LA, Bresnick EH, Brest P, Bridges D, Bringer MA, Brini M, Brito GC, Brodin B, Brookes PS, Brown EJ, Brown K, Broxmeyer HE, Bruhat A, Brum PC, Brumell JH, Brunetti-Pierri N, Bryson-Richardson RJ, Buch S, Buchan AM, Budak H, Bulavin DV, Bultman SJ, Bultynck G, Bumbasirevic V, Burelle Y, Burke RE, Burmeister M, Bütikofer P, Caberlotto L, Cadwell K, Cahova M, Cai D, Cai J, Cai Q, Calatayud S, Camougrand N, Campanella M, Campbell GR, Campbell M, Campello S, Candau R, Caniggia I, Cantoni L, Cao L, Caplan AB, Caraglia M, Cardinali C, Cardoso SM, Carew JS, Carleton LA, Carlin CR, Carloni S, Carlsson SR, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carra S, Carrier A, Carroll B, Casas C, Casas J, Cassinelli G, Castets P, Castro-Obregon S, Cavallini G, Ceccherini I, Cecconi F, Cederbaum AI, Ceña V, Cenci S, Cerella C, Cervia D, Cetrullo S, Chaachouay H, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chamilos G, Chan EY, Chan MT, Chandra D, Chandra P, Chang CP, Chang RC, Chang TY, Chatham JC, Chatterjee S, Chauhan S, Che Y, Cheetham ME, Cheluvappa R, Chen CJ, Chen G, Chen GC, Chen G, Chen H, Chen JW, Chen JK, Chen M, Chen M, Chen P, Chen Q, Chen Q, Chen SD, Chen S, Chen SS, Chen W, Chen WJ, Chen WQ, Chen W, Chen X, Chen YH, Chen YG, Chen Y, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen Y, Chen Z, Chen Z, Cheng A, Cheng CH, Cheng H, Cheong H, Cherry S, Chesney J, Cheung CH, Chevet E, Chi HC, Chi SG, Chiacchiera F, Chiang HL, Chiarelli R, Chiariello M, Chieppa M, Chin LS, Chiong M, Chiu GN, Cho DH, Cho SG, Cho WC, Cho YY, Cho YS, Choi AM, Choi EJ, Choi EK, Choi J, Choi ME, Choi SI, Chou TF, Chouaib S, Choubey D, Choubey V, Chow KC, Chowdhury K, Chu CT, Chuang TH, Chun T, Chung H, Chung T, Chung YL, Chwae YJ, Cianfanelli V, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016; 12(1):1-222. PMID: 26799652.
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    20. West DW, Baehr LM, Marcotte GR, Chason CM, Tolento L, Gomes AV, Bodine SC, Baar K. Acute resistance exercise activates rapamycin-sensitive and -insensitive mechanisms that control translational activity and capacity in skeletal muscle. J Physiol. 2016 Jan 15; 594(2):453-68. PMID: 26548696.
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    21. Gomes AV, Kazmierczak K, Cheah JX, Gilda JE, Yuan CC, Zhou Z, Szczesna-Cordary D. Proteomic analysis of physiological versus pathological cardiac remodeling in animal models expressing mutations in myosin essential light chains. J Muscle Res Cell Motil. 2015 Dec; 36(6):447-61. PMID: 26668058.
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    22. Gomes AV, Rajasekaran NS, Pi X. Redox Signaling and the Cardiovascular and Skeletal Muscle System. Oxid Med Cell Longev. 2015; 2015:849095. PMID: 26523200.
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    23. Ghosh R, Alajbegovic A, Gomes AV. NSAIDs and Cardiovascular Diseases: Role of Reactive Oxygen Species. Oxid Med Cell Longev. 2015; 2015:536962. PMID: 26457127.
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    24. Gilda JE, Ghosh R, Cheah JX, West TM, Bodine SC, Gomes AV. Western Blotting Inaccuracies with Unverified Antibodies: Need for a Western Blotting Minimal Reporting Standard (WBMRS). PLoS One. 2015; 10(8):e0135392. PMID: 26287535.
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    25. Carbonell T, Gomes AV. Dynamic regulation of the proteasome by systolic overload. J Mol Cell Cardiol. 2015 Oct; 87:1-3. PMID: 26219953.
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    26. Lindsey ML, Mayr M, Gomes AV, Delles C, Arrell DK, Murphy AM, Lange RA, Costello CE, Jin YF, Laskowitz DT, Sam F, Terzic A, Van Eyk J, Srinivas PR. Transformative Impact of Proteomics on Cardiovascular Health and Disease: A Scientific Statement From the American Heart Association. Circulation. 2015 Sep 01; 132(9):852-72. PMID: 26195497.
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    27. Negroni JA, Morotti S, Lascano EC, Gomes AV, Grandi E, Puglisi JL, Bers DM. ß-adrenergic effects on cardiac myofilaments and contraction in an integrated rabbit ventricular myocyte model. J Mol Cell Cardiol. 2015 Apr; 81:162-75. PMID: 25724724.
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    28. Gilda JE, Gomes AV. Western blotting using in-gel protein labeling as a normalization control: stain-free technology. Methods Mol Biol. 2015; 1295:381-91. PMID: 25820735.
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    29. Ghosh R, Gilda JE, Gomes AV. The necessity of and strategies for improving confidence in the accuracy of western blots. Expert Rev Proteomics. 2014 Oct; 11(5):549-60. PMID: 25059473.
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    30. Jamart C, Gomes AV, Dewey S, Deldicque L, Raymackers JM, Francaux M. Regulation of ubiquitin-proteasome and autophagy pathways after acute LPS and epoxomicin administration in mice. BMC Musculoskelet Disord. 2014 May 22; 15:166. PMID: 24885455.
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    31. Wecksler AT, Hwang SH, Wettersten HI, Gilda JE, Patton A, Leon LJ, Carraway KL, Gomes AV, Baar K, Weiss RH, Hammock BD. Novel sorafenib-based structural analogues: in-vitro anticancer evaluation of t-MTUCB and t-AUCMB. Anticancer Drugs. 2014 Apr; 25(4):433-46. PMID: 24525589.
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    32. Narasimhan M, Hong J, Atieno N, Muthusamy VR, Davidson CJ, Abu-Rmaileh N, Richardson RS, Gomes AV, Hoidal JR, Rajasekaran NS. Nrf2 deficiency promotes apoptosis and impairs PAX7/MyoD expression in aging skeletal muscle cells. Free Radic Biol Med. 2014 Jun; 71:402-14. PMID: 24613379.
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    33. Puglisi JL, Goldspink PH, Gomes AV, Utter MS, Bers DM, Solaro RJ. Influence of a constitutive increase in myofilament Ca(2+)-sensitivity on Ca(2+)-fluxes and contraction of mouse heart ventricular myocytes. Arch Biochem Biophys. 2014 Jun 15; 552-553:50-9. PMID: 24480308.
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    34. Gomes AV. Genetics of proteasome diseases. Scientifica (Cairo). 2013; 2013:637629. PMID: 24490108.
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    35. Cui Z, Hwang SM, Gomes AV. Identification of the immunoproteasome as a novel regulator of skeletal muscle differentiation. Mol Cell Biol. 2014 Jan; 34(1):96-109. PMID: 24164898.
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    36. Cui Z, Scruggs SB, Gilda JE, Ping P, Gomes AV. Regulation of cardiac proteasomes by ubiquitination, SUMOylation, and beyond. J Mol Cell Cardiol. 2014 Jun; 71:32-42. PMID: 24140722.
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    37. Cui Z, Gilda JE, Gomes AV. Crude and purified proteasome activity assays are affected by type of microplate. Anal Biochem. 2014 Feb 01; 446:44-52. PMID: 24141075.
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    38. Domenighetti AA, Chu PH, Wu T, Sheikh F, Gokhin DS, Guo LT, Cui Z, Peter AK, Christodoulou DC, Parfenov MG, Gorham JM, Li DY, Banerjee I, Lai X, Witzmann FA, Seidman CE, Seidman JG, Gomes AV, Shelton GD, Lieber RL, Chen J. Loss of FHL1 induces an age-dependent skeletal muscle myopathy associated with myofibrillar and intermyofibrillar disorganization in mice. Hum Mol Genet. 2014 Jan 01; 23(1):209-25. PMID: 23975679.
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    39. Dewey S, Lai X, Witzmann FA, Sohal M, Gomes AV. Proteomic analysis of hearts from Akita mice suggests that increases in soluble epoxide hydrolase and antioxidative programming are key changes in early stages of diabetic cardiomyopathy. J Proteome Res. 2013 Sep 06; 12(9):3920-33. PMID: 23848590.
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    40. Kannan S, Muthusamy VR, Whitehead KJ, Wang L, Gomes AV, Litwin SE, Kensler TW, Abel ED, Hoidal JR, Rajasekaran NS. Nrf2 deficiency prevents reductive stress-induced hypertrophic cardiomyopathy. Cardiovasc Res. 2013 Oct 01; 100(1):63-73. PMID: 23761402.
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    41. Gilda JE, Gomes AV. Stain-Free total protein staining is a superior loading control to ß-actin for Western blots. Anal Biochem. 2013 Sep 15; 440(2):186-8. PMID: 23747530.
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    42. Gilda JE, Gomes AV. How phosphorylated can it get? Cardiac myosin binding protein C phosphorylation in heart failure. J Mol Cell Cardiol. 2013 Sep; 62:108-10. PMID: 23732927.
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    43. Rajagopalan V, Zhao M, Reddy S, Fajardo G, Wang X, Dewey S, Gomes AV, Bernstein D. Altered ubiquitin-proteasome signaling in right ventricular hypertrophy and failure. Am J Physiol Heart Circ Physiol. 2013 Aug 15; 305(4):H551-62. PMID: 23729213.
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    44. Boggess MV, Lippolis JD, Hurkman WJ, Fagerquist CK, Briggs SP, Gomes AV, Righetti PG, Bala K. The need for agriculture phenotyping: "moving from genotype to phenotype". J Proteomics. 2013 Nov 20; 93:20-39. PMID: 23563084.
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    45. Szczesna-Cordary D, Morimoto S, Gomes AV, Moore JR. Cardiomyopathies: classification, clinical characterization, and functional phenotypes. Biochem Res Int. 2012; 2012:870942. PMID: 23304510.
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    46. Iorga A, Dewey S, Partow-Navid R, Gomes AV, Eghbali M. Pregnancy is associated with decreased cardiac proteasome activity and oxidative stress in mice. PLoS One. 2012; 7(11):e48601. PMID: 23166589.
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    47. Pinto JR, Gomes AV, Jones MA, Liang J, Nguyen S, Miller T, Parvatiyar MS, Potter JD. The functional properties of human slow skeletal troponin T isoforms in cardiac muscle regulation. J Biol Chem. 2012 Oct 26; 287(44):37362-70. PMID: 22977240.
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    48. Gomes AV, Waddell DS, Siu R, Stein M, Dewey S, Furlow JD, Bodine SC. Upregulation of proteasome activity in muscle RING finger 1-null mice following denervation. FASEB J. 2012 Jul; 26(7):2986-99. PMID: 22508689.
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    49. Xu Q, Cui Z, Venkatraman G, Gomes AV. The use of biophysical proteomic techniques in advancing our understanding of diseases. Biophys Rev. 2012 Jun; 4(2):125-135. PMID: 28510094.
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    50. Cui Z, Dewey S, Gomes AV. Cardioproteomics: advancing the discovery of signaling mechanisms involved in cardiovascular diseases. Am J Cardiovasc Dis. 2011; 1(3):274-92. PMID: 22254205.
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    51. Hwee DT, Gomes AV, Bodine SC. Cardiac proteasome activity in muscle ring finger-1 null mice at rest and following synthetic glucocorticoid treatment. Am J Physiol Endocrinol Metab. 2011 Nov; 301(5):E967-77. PMID: 21828340.
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    52. Dewey S, Xu Q, Gomes A. Static and dynamic properties of the HCM myocardium. J Mol Cell Cardiol. 2010 Nov; 49(5):715-8. PMID: 20705073.
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    53. Divald A, Kivity S, Wang P, Hochhauser E, Roberts B, Teichberg S, Gomes AV, Powell SR. Myocardial ischemic preconditioning preserves postischemic function of the 26S proteasome through diminished oxidative damage to 19S regulatory particle subunits. Circ Res. 2010 Jun 25; 106(12):1829-38. PMID: 20431057.
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    54. Dewey S, Gomes AV. Non-antigen processing immunoproteasomes in diabetic hearts? J Mol Cell Cardiol. 2010 Jul; 49(1):1-4. PMID: 20382154.
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    55. Xu Q, Dewey S, Nguyen S, Gomes AV. Malignant and benign mutations in familial cardiomyopathies: insights into mutations linked to complex cardiovascular phenotypes. J Mol Cell Cardiol. 2010 May; 48(5):899-909. PMID: 20298698.
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    56. Tikunova SB, Liu B, Swindle N, Little SC, Gomes AV, Swartz DR, Davis JP. Effect of calcium-sensitizing mutations on calcium binding and exchange with troponin C in increasingly complex biochemical systems. Biochemistry. 2010 Mar 09; 49(9):1975-84. PMID: 20128626.
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    57. Willott RH, Gomes AV, Chang AN, Parvatiyar MS, Pinto JR, Potter JD. Mutations in Troponin that cause HCM, DCM AND RCM: what can we learn about thin filament function? J Mol Cell Cardiol. 2010 May; 48(5):882-92. PMID: 19914256.
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    58. Mayr M, Grainger D, Mayr U, Leroyer AS, Leseche G, Sidibe A, Herbin O, Yin X, Gomes A, Madhu B, Griffiths JR, Xu Q, Tedgui A, Boulanger CM. Proteomics, metabolomics, and immunomics on microparticles derived from human atherosclerotic plaques. Circ Cardiovasc Genet. 2009 Aug; 2(4):379-88. PMID: 20031610.
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    59. Mayr M, Liem D, Zhang J, Li X, Avliyakulov NK, Yang JI, Young G, Vondriska TM, Ladroue C, Madhu B, Griffiths JR, Gomes A, Xu Q, Ping P. Proteomic and metabolomic analysis of cardioprotection: Interplay between protein kinase C epsilon and delta in regulating glucose metabolism of murine hearts. J Mol Cell Cardiol. 2009 Feb; 46(2):268-77. PMID: 19027023.
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    60. Gomes AV, Young GW, Wang Y, Zong C, Eghbali M, Drews O, Lu H, Stefani E, Ping P. Contrasting proteome biology and functional heterogeneity of the 20 S proteasome complexes in mammalian tissues. Mol Cell Proteomics. 2009 Feb; 8(2):302-15. PMID: 18931337.
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    61. Wen Y, Pinto JR, Gomes AV, Xu Y, Wang Y, Wang Y, Potter JD, Kerrick WG. Functional consequences of the human cardiac troponin I hypertrophic cardiomyopathy mutation R145G in transgenic mice. J Biol Chem. 2008 Jul 18; 283(29):20484-94. PMID: 18430738.
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    62. Baldán A, Gomes AV, Ping P, Edwards PA. Loss of ABCG1 results in chronic pulmonary inflammation. J Immunol. 2008 Mar 01; 180(5):3560-8. PMID: 18292583.
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    63. Lounes KC, Demeler B, Anderson DE, Gomes AW, Potter JD, Nassar R, Anderson PA. Cardiac troponin T forms a tetramer in vitro. Biochemistry. 2008 Feb 19; 47(7):1970-6. PMID: 18197700.
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    64. Drews O, Wildgruber R, Zong C, Sukop U, Nissum M, Weber G, Gomes AV, Ping P. Mammalian proteasome subpopulations with distinct molecular compositions and proteolytic activities. Mol Cell Proteomics. 2007 Nov; 6(11):2021-31. PMID: 17660509.
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    65. Ross EM, Mateu D, Gomes AV, Arana C, Tran T, Litosch I. Structural determinants for phosphatidic acid regulation of phospholipase C-beta1. J Biol Chem. 2006 Nov 03; 281(44):33087-94. PMID: 16950781.
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    66. Gomes AV, Zong C, Ping P. Protein degradation by the 26S proteasome system in the normal and stressed myocardium. Antioxid Redox Signal. 2006 Sep-Oct; 8(9-10):1677-91. PMID: 16987021.
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    67. Zong C, Gomes AV, Drews O, Li X, Young GW, Berhane B, Qiao X, French SW, Bardag-Gorce F, Ping P. Regulation of murine cardiac 20S proteasomes: role of associating partners. Circ Res. 2006 Aug 18; 99(4):372-80. PMID: 16857963.
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    68. Gomes AV, Zong C, Edmondson RD, Li X, Stefani E, Zhang J, Jones RC, Thyparambil S, Wang GW, Qiao X, Bardag-Gorce F, Ping P. Mapping the murine cardiac 26S proteasome complexes. Circ Res. 2006 Aug 18; 99(4):362-71. PMID: 16857966.
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    69. Gomes AV, Harada K, Potter JD. A mutation in the N-terminus of troponin I that is associated with hypertrophic cardiomyopathy affects the Ca(2+)-sensitivity, phosphorylation kinetics and proteolytic susceptibility of troponin. J Mol Cell Cardiol. 2005 Nov; 39(5):754-65. PMID: 16005017.
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    70. Gomes AV, Liang J, Potter JD. Mutations in human cardiac troponin I that are associated with restrictive cardiomyopathy affect basal ATPase activity and the calcium sensitivity of force development. J Biol Chem. 2005 Sep 02; 280(35):30909-15. PMID: 15961398.
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    71. Gomes AV, Venkatraman G, Potter JD. The miscommunicative cardiac cell: when good proteins go bad. Ann N Y Acad Sci. 2005 Jun; 1047:30-7. PMID: 16093482.
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    72. Gomes AV, Zong C, Edmondson RD, Berhane BT, Wang GW, Le S, Young G, Zhang J, Vondriska TM, Whitelegge JP, Jones RC, Joshua IG, Thyparambil S, Pantaleon D, Qiao J, Loo J, Ping P. The murine cardiac 26S proteasome: an organelle awaiting exploration. Ann N Y Acad Sci. 2005 Jun; 1047:197-207. PMID: 16093497.
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    73. Venkatraman G, Gomes AV, Kerrick WG, Potter JD. Characterization of troponin T dilated cardiomyopathy mutations in the fetal troponin isoform. J Biol Chem. 2005 May 06; 280(18):17584-92. PMID: 15623536.
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    74. Gomes AV, Venkatraman G, Davis JP, Tikunova SB, Engel P, Solaro RJ, Potter JD. Cardiac troponin T isoforms affect the Ca(2+) sensitivity of force development in the presence of slow skeletal troponin I: insights into the role of troponin T isoforms in the fetal heart. J Biol Chem. 2004 Nov 26; 279(48):49579-87. PMID: 15358779.
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    75. Gomes AV, Barnes JA, Harada K, Potter JD. Role of troponin T in disease. Mol Cell Biochem. 2004 08; 263(1-2):115-29. PMID: 15524172.
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    76. Gomes AV, Potter JD. Cellular and molecular aspects of familial hypertrophic cardiomyopathy caused by mutations in the cardiac troponin I gene. Mol Cell Biochem. 2004 08; 263(1-2):99-114. PMID: 15524171.
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    77. Barnes JA, Singh S, Gomes AV. Protease activated receptors in cardiovascular function and disease. Mol Cell Biochem. 2004 Aug; 263(1):227-39. PMID: 27520681.
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    78. Barnes JA, Singh S, Gomes AV. Protease activated receptors in cardiovascular function and disease. Mol Cell Biochem. 2004 Aug; 263(1-2):227-39. PMID: 15524183.
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    79. Gomes AV, Potter JD. Molecular and cellular aspects of troponin cardiomyopathies. Ann N Y Acad Sci. 2004 May; 1015:214-24. PMID: 15201162.
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    80. Everhart D, Cartier GE, Malhotra A, Gomes AV, McIntosh JM, Luetje CW. Determinants of potency on alpha-conotoxin MII, a peptide antagonist of neuronal nicotinic receptors. Biochemistry. 2004 Mar 16; 43(10):2732-7. PMID: 15005608.
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    81. Yuan T, Gomes AV, Barnes JA, Hunter HN, Vogel HJ. Spectroscopic characterization of the calmodulin-binding and autoinhibitory domains of calcium/calmodulin-dependent protein kinase I. Arch Biochem Biophys. 2004 Jan 15; 421(2):192-206. PMID: 14984199.
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    82. Gutierrez-Ford C, Levay K, Gomes AV, Perera EM, Som T, Kim YM, Benovic JL, Berkovitz GD, Slepak VZ. Characterization of tescalcin, a novel EF-hand protein with a single Ca2+-binding site: metal-binding properties, localization in tissues and cells, and effect on calcineurin. Biochemistry. 2003 Dec 16; 42(49):14553-65. PMID: 14661968.
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    83. Venkatraman G, Harada K, Gomes AV, Kerrick WG, Potter JD. Different functional properties of troponin T mutants that cause dilated cardiomyopathy. J Biol Chem. 2003 Oct 24; 278(43):41670-6. PMID: 12923187.
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    84. Gomes AV, Potter JD, Szczesna-Cordary D. The role of troponins in muscle contraction. IUBMB Life. 2002 Dec; 54(6):323-33. PMID: 12665242.
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    85. Gomes AV, Guzman G, Zhao J, Potter JD. Cardiac troponin T isoforms affect the Ca2+ sensitivity and inhibition of force development. Insights into the role of troponin T isoforms in the heart. J Biol Chem. 2002 Sep 20; 277(38):35341-9. PMID: 12093807.
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    86. Barnes JA, Gomes AV. Proteolytic signals in the primary structure of annexins. Mol Cell Biochem. 2002 Feb; 231(1-2):1-7. PMID: 11952151.
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    87. Lang R, Gomes AV, Zhao J, Housmans PR, Miller T, Potter JD. Functional analysis of a troponin I (R145G) mutation associated with familial hypertrophic cardiomyopathy. J Biol Chem. 2002 Apr 05; 277(14):11670-8. PMID: 11801593.
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    88. Szczesna D, Ghosh D, Li Q, Gomes AV, Guzman G, Arana C, Zhi G, Stull JT, Potter JD. Familial hypertrophic cardiomyopathy mutations in the regulatory light chains of myosin affect their structure, Ca2+ binding, and phosphorylation. J Biol Chem. 2001 Mar 09; 276(10):7086-92. PMID: 11102452.
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    89. Miller T, Szczesna D, Housmans PR, Zhao J, de Freitas F, Gomes AV, Culbreath L, McCue J, Wang Y, Xu Y, Kerrick WG, Potter JD. Abnormal contractile function in transgenic mice expressing a familial hypertrophic cardiomyopathy-linked troponin T (I79N) mutation. J Biol Chem. 2001 Feb 09; 276(6):3743-55. PMID: 11060294.
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    90. Cuervo AM, Gomes AV, Barnes JA, Dice JF. Selective degradation of annexins by chaperone-mediated autophagy. J Biol Chem. 2000 Oct 27; 275(43):33329-35. PMID: 10938088.
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    91. Gomes AV, Barnes JA, Vogel HJ. Spectroscopic characterization of the interaction between calmodulin-dependent protein kinase I and calmodulin. Arch Biochem Biophys. 2000 Jul 01; 379(1):28-36. PMID: 10864438.
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    92. Pehowich DJ, Gomes AV, Barnes JA. Fatty acid composition and possible health effects of coconut constituents. West Indian Med J. 2000 Jun; 49(2):128-33. PMID: 10948851.
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    93. Gomes AV, Barnes JA. Cost- and time-efficient gel electrophoresis for mini-gel systems. Anal Biochem. 1998 Jun 15; 260(1):106-8. PMID: 9648661.
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    94. Gomes AV, Sirju-Charran G, Barnes JA. Major proteins of yam bean tubers. Phytochemistry. 1997 Sep; 46(2):185-93. PMID: 9311151.
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    95. Gomes AV, Barnes JA. Protein phosphatases are pest containing proteins. Biochem Mol Biol Int. 1997 Jan; 41(1):65-73. PMID: 9043636.
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    96. Gomes AV, Barnes JA. Pest sequences in EF-hand calcium-binding proteins. Biochem Mol Biol Int. 1995 Nov; 37(5):853-60. PMID: 8624490.
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    97. Barnes JA, Gomes AV. PEST sequences in calmodulin-binding proteins. Mol Cell Biochem. 1995 Aug-Sep; 149-150:17-27. PMID: 8569726.
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    98. Gomes AV. Calmodulin's warm embrace. Bioessays. 1994 Nov; 16(11):853. PMID: 7840762.
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