Kenichi Nakajima

Title(s)Assistant Adjunct Professor, Med: Dermatology
SchoolSchool of Medicine
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    1. Establishment of a 123I-meta-iodobenzylguanidine normal database for D-SPECT using Japanese and Italian data. Ann Nucl Med. 2025 Sep; 39(9):952-965. Zhang X, Nakajima K, Acampa W, Assante R, D'Antonio A, Okuda K, Yokoyama K, Kinuya S. PMID: 40455381; PMCID: PMC12378134.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Studies on Gene Enhancer with KSHV mini-chromatin. bioRxiv. 2025 Mar 24. Inagaki T, Kumar A, Wang KH, Komaki S, Espera JM, Bautista CSA, Nakajima KI, Izumiya C, Izumiya Y. PMID: 40196677; PMCID: PMC11974746.
      View in: PubMed   Mentions: 1  
    3. Material Efficiency and Circularity Goals to Achieve a Carbon-Neutral Society by 2050. Environ Sci Technol. 2025 Apr 01; 59(12):6025-6036. Hata S, Nansai K, Shigetomi Y, Kito M, Nakajima K. PMID: 40111265; PMCID: PMC11966779.
      View in: PubMed   Mentions: 1     Fields:    
    4. Design, development, and evaluation of gene therapeutics specific to KSHV-associated diseases. bioRxiv. 2025 Feb 19. Inagaki T, Espera J, Wang KH, Komaki S, Nair S, Davis RR, Kumar A, Nakajima KI, Izumiya Y. PMID: 40027700; PMCID: PMC11870588.
      View in: PubMed   Mentions:
    5. Long-term survival and durable recovery of heart failure in patients with triglyceride deposit cardiomyovasculopathy treated with tricaprin. Nat Cardiovasc Res. 2025 Mar; 4(3):266-274. Hirano KI, Okamura S, Sugimura K, Miyauchi H, Nakano Y, Nochioka K, Hashimoto C, Iwanaga Y, Nakajima K, Yamaguchi S, Yasui Y, Shimamoto S, Hirano M, Okune M, Nishimura Y, Shimoyama H, Nagasawa Y, Amano T, Kuniyoshi S, Hui SP, Zaima N, Ikeda Y, Yamada T, Fujimoto S, Sakata Y, Kobayashi K. PMID: 39948308.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    6. [Application of the IR Method Using a Normal Database Created by FBP Method with No Correction in 99mTc Myocardial Perfusion SPECT]. Nihon Hoshasen Gijutsu Gakkai Zasshi. 2025; 81(4). Segawa K, Shibutani T, Yamaguchi Y, Ichikawa H, Konishi T, Yoneyama H, Nakajima K. PMID: 39993776.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Ferredoxin 2 Is Critical for Tumor Suppression and Lipid Homeostasis but Dispensable for Embryonic Development. Am J Pathol. 2025 Apr; 195(4):705-716. Zhang J, Zhang Y, Mohibi S, Perng V, Bustamante M, Shi Y, Nakajima K, Chen M, Chen X. PMID: 39732391.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    8. A LANA peptide inhibits tumor growth by inducing CHD4 protein cleavage and triggers cell death. Cell Chem Biol. 2024 Nov 21; 31(11):1909-1925.e7. Miura H, Wang KH, Inagaki T, Chuang F, Shimoda M, Izumiya C, Watanabe T, Davis RR, Tepper CG, Komaki S, Nakajima KI, Kumar A, Izumiya Y. PMID: 39488208; PMCID: PMC11588034.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    9. Evaluation of 3β-hydroxysteroid dehydrogenase activity using progesterone and androgen receptors-mediated transactivation. Front Endocrinol (Lausanne). 2024; 15:1480722. Yazawa T, Watanabe Y, Yokohama Y, Imamichi Y, Hasegawa K, Nakajima KI, Kitano T, Ida T, Sato T, Islam MS, Umezawa A, Takahashi S, Kato Y, Jahan S, Kawabe JI. PMID: 39415787; PMCID: PMC11479897.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    10. A novel algorithm developed using machine learning and a J-ACCESS database can estimate defect scores from myocardial perfusion single-photon emission tomography images. Ann Nucl Med. 2024 Dec; 38(12):980-988. Kiso K, Nakajima K, Nimura Y, Nishimura T. PMID: 39210200; PMCID: PMC11538165.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    11. An atlas of chromatin landscape in KSHV-infected cells during de novo infection and reactivation. Virology. 2024 09; 597:110146. Inagaki T, Kumar A, Komaki S, Nakajima KI, Izumiya Y. PMID: 38909515.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    12. Absolute quantitation of sympathetic nerve activity using [123I] metaiodobenzylguanidine SPECT-CT in neurology. EJNMMI Rep. 2024 Jun 01; 8(1):15. Saito S, Nakajima K, Komatsu J, Shibutani T, Wakabayashi H, Mori H, Takata A, Ono K, Kinuya S. PMID: 38822219; PMCID: PMC11143090.
      View in: PubMed   Mentions: 3  
    13. Kaposi's sarcoma-associated herpesvirus (KSHV) LANA prevents KSHV episomes from degradation. J Virol. 2024 02 20; 98(2):e0126823. Nakajima K-i, Inagaki T, Espera JM, Izumiya Y. PMID: 38240588; PMCID: PMC10878079.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    14. Correction: Practice recommendation for measuring washout rates in 123I-BMIPP fatty acid images. Ann Nucl Med. 2024 Jan; 38(1):9. Nakajima K, Miyauchi H, Hirano KI, Fujimoto S, Kawahito M, Iimori T, Kudo T. PMID: 37837529; PMCID: PMC10766721.
      View in: PubMed   Mentions:    Fields:    
    15. Detectability of cold tumors by xSPECT bone technology compared with hot tumors: a supine phantom study. Phys Eng Sci Med. 2024 Mar; 47(1):287-294. Shibutani T, Konishi T, Ichikawa H, Onoguchi M, Yoneyama H, Ito T, Okuda K, Nakajima K. PMID: 38117462.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Phantom-Based Standardization Method for 123I-metaiodobenzylguanidine Heart-to-Mediastinum Ratio Validated by D-SPECT Versus Anger Camera. Ann Nucl Cardiol. 2023; 9(1):85-90. Yamashita S, Nakajima K, Okuda K, Yamamoto H, Shibutani T, Yoneyama T, Tsuji S, Yokoyama K. PMID: 38058581; PMCID: PMC10696155.
      View in: PubMed   Mentions: 2  
    17. Practice Recommendation for Measuring Washout Rates in 123I-BMIPP Fatty Acid Images. Ann Nucl Cardiol. 2023; 9(1):3-10. Nakajima K, Miyauchi H, Hirano KI, Fujimoto S, Kawahito M, Iimori T, Kudo T, Japanese Society of Nuclear Cardiology working group. PMID: 38058580; PMCID: PMC10696152.
      View in: PubMed   Mentions: 1  
    18. Three-Dimensional Heart Segmentation and Absolute Quantitation of Cardiac 123I-metaiodobenzylguanidine Sympathetic Imaging Using SPECT/CT. Ann Nucl Cardiol. 2023; 9(1):61-67. Saito S, Nakajima K, Shibutani T, Wakabayashi H, Yoneyama H, Konishi T, Mori H, Takata A, Kinuya S. PMID: 38058582; PMCID: PMC10696146.
      View in: PubMed   Mentions: 2  
    19. Myocardial perfusion imaging with retrospective gating and integrated correction of attenuation, scatter, respiration, motion, and arrhythmia. J Nucl Cardiol. 2023 12; 30(6):2773-2789. Nakajima K, Shibutani T, Massanes F, Shimizu T, Yoshida S, Onoguchi M, Kinuya S, Vija AH. PMID: 37758961; PMCID: PMC10682219.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    20. Practice recommendation for measuring washout rates in 123I-BMIPP fatty acid images. Ann Nucl Med. 2024 Jan; 38(1):1-8. Nakajima K, Miyauchi H, Hirano KI, Fujimoto S, Kawahito M, Iimori T, Kudo T. PMID: 37691078; PMCID: PMC10766729.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    21. Inhibition of high-fat diet-induced inflammatory responses in adipose tissue by SF1-expressing neurons of the ventromedial hypothalamus. Cell Rep. 2023 06 27; 42(6):112627. Rashid M, Kondoh K, Palfalvi G, Nakajima KI, Minokoshi Y. PMID: 37339627.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    22. J-ACCESS investigation and nuclear cardiology in Japan: implications for heart failure. Ann Nucl Med. 2023 Jun; 37(6):317-327. Nakajima K, Nishimura T. PMID: 37039970; PMCID: PMC10195738.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    23. Neural insights into sweet taste transduction and hunger-induced taste modification in mice. Biosci Biotechnol Biochem. 2022 Oct 20; 86(11):1485-1489. Nakajima KI. PMID: 35998309.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    24. Predictive factors for the effectiveness of novel androgen receptor axis-targeted agents in patients with metastatic prostate cancer. Int J Urol. 2022 12; 29(12):1477-1487. Koshiro N, Nakajima K, Oyama M, Kaneko G, Takahashi S, Matsuyama H, Shiina H, Ichikawa T, Horikoshi H, Hashine K, Sugiyama Y, Miyao T, Kamiyama M, Harada K, Ito A, Mizokami A, PROSTAT-BSI Investigators. PMID: 36070138.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    25. Normal and Range Value Evaluations Using Heart Risk View-Function Based on the Japanese Societyof Nuclear Medicine Working Group Database. Ann Nucl Cardiol. 2022; 8(1):51-56. Tatsuno K, Okuda K, Nakajima K, Saito H, Shibutani T, Onoguchi M, Takahashi T, Mochizuki T, Watanabe N, Matoba M. PMID: 36540186; PMCID: PMC9749745.
      View in: PubMed   Mentions: 1  
    26. Efficacy of Androgen Receptor-targeted Drugs After Prostate Cancer Recurrence With Bone Metastases: PROSTAT-BSI Sub-analysis. Anticancer Res. 2022 Jun; 42(6):3099-3108. Kamijima T, Yaegashi H, Mizokami A, Nakajima K, Matsuyama H, Ichikawa T, Nishimoto K, Takahashi S, Shiina H, Horikoshi H, Hashine K, Sugiyama Y, Miyao T, Kamiyama M, Harada K, Ito A, Enokida H. PMID: 35641302.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    27. KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4. Cell Rep. 2022 05 10; 39(6):110788. Kumar A, Lyu Y, Yanagihashi Y, Chantarasrivong C, Majerciak V, Salemi M, Wang KH, Inagaki T, Chuang F, Davis RR, Tepper CG, Nakano K, Izumiya C, Shimoda M, Nakajima KI, Merleev A, Zheng ZM, Campbell M, Izumiya Y. PMID: 35545047; PMCID: PMC9153692.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    28. JCS 2022 Guideline Focused Update on Diagnosis and Treatment in Patients With Stable Coronary Artery Disease. Circ J. 2022 04 25; 86(5):882-915. Nakano S, Kohsaka S, Chikamori T, Fukushima K, Kobayashi Y, Kozuma K, Manabe S, Matsuo H, Nakamura M, Ohno T, Sawano M, Toda K, Ueda Y, Yokoi H, Gatate Y, Kasai T, Kawase Y, Matsumoto N, Mori H, Nakazato R, Niimi N, Saito Y, Shintani A, Watanabe I, Watanabe Y, Ikari Y, Jinzaki M, Kosuge M, Nakajima K, Kimura T, JCS Joint Working Group. PMID: 35283401.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    29. Efficacy of New Therapies for Relapse After Docetaxel Treatment of Bone Metastatic Castration-resistant Prostate Cancer in Clinical Practice. Anticancer Res. 2022 Mar; 42(3):1465-1475. Mizokami A, Nishimoto K, Matsuyama H, Ichikawa T, Takahashi S, Shiina H, Hashine K, Sugiyama Y, Kamiyama M, Enokida H, Nakajima K. PMID: 35220240.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    30. KSHV transactivator-derived small peptide traps coactivators to attenuate MYC and inhibits leukemia and lymphoma cell growth. Commun Biol. 2021 12 02; 4(1):1330. Shimoda M, Lyu Y, Wang KH, Kumar A, Miura H, Meckler JF, Davis RR, Chantarasrivong C, Izumiya C, Tepper CG, Nakajima KI, Tuscano J, Barisone G, Izumiya Y. PMID: 34857874; PMCID: PMC8639922.
      View in: PubMed   Mentions: 5  Translation:HumansCells
    31. Cardiovascular event risk estimated by myocardial perfusion SPECT combined with clinical data. J Cardiol. 2022 07; 80(1):64-71. Sakatani T, Nakajima K, Nishimura T. PMID: 34728122.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    32. Performance of SwiftScan planar and SPECT technology using low-energy high-resolution and sensitivity collimator compared with Siemens SPECT system. Nucl Med Commun. 2021 Jul 01; 42(7):732-737. Shibutani T, Onoguchi M, Yoneyama H, Konishi T, Nakajima K. PMID: 33741862.
      View in: PubMed   Mentions: 3     Fields:    
    33. Prognosis of patients with prostate cancer and bone metastasis from the Japanese Prostatic Cancer Registry of Standard Hormonal and Chemotherapy Using Bone Scan Index cohort study. Int J Urol. 2021 09; 28(9):955-963. Nakajima K, Mizokami A, Matsuyama H, Ichikawa T, Kaneko G, Takahashi S, Shiina H, Horikoshi H, Hashine K, Sugiyama Y, Miyao T, Kamiyama M, Harada K, Ito A, PROSTAT-BSI Investigators. PMID: 34148264; PMCID: PMC8453930.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    34. Proximity Biotin Labeling Reveals Kaposi's Sarcoma-Associated Herpesvirus Interferon Regulatory Factor Networks. J Virol. 2021 04 12; 95(9). Kumar A, Salemi M, Bhullar R, Guevara-Plunkett S, Lyu Y, Wang KH, Izumiya C, Campbell M, Nakajima KI, Izumiya Y. PMID: 33597212; PMCID: PMC8104114.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    35. JCS 2018 Guideline on Diagnosis of Chronic Coronary Heart Diseases. Circ J. 2021 03 25; 85(4):402-572. Yamagishi M, Tamaki N, Akasaka T, Ikeda T, Ueshima K, Uemura S, Otsuji Y, Kihara Y, Kimura K, Kimura T, Kusama Y, Kumita S, Sakuma H, Jinzaki M, Daida H, Takeishi Y, Tada H, Chikamori T, Tsujita K, Teraoka K, Nakajima K, Nakata T, Nakatani S, Nogami A, Node K, Nohara A, Hirayama A, Funabashi N, Miura M, Mochizuki T, Yokoi H, Yoshioka K, Watanabe M, Asanuma T, Ishikawa Y, Ohara T, Kaikita K, Kasai T, Kato E, Kamiyama H, Kawashiri M, Kiso K, Kitagawa K, Kido T, Kinoshita T, Kiriyama T, Kume T, Kurata A, Kurisu S, Kosuge M, Kodani E, Sato A, Shiono Y, Shiomi H, Taki J, Takeuchi M, Tanaka A, Tanaka N, Tanaka R, Nakahashi T, Nakahara T, Nomura A, Hashimoto A, Hayashi K, Higashi M, Hiro T, Fukamachi D, Matsuo H, Matsumoto N, Miyauchi K, Miyagawa M, Yamada Y, Yoshinaga K, Wada H, Watanabe T, Ozaki Y, Kohsaka S, Shimizu W, Yasuda S, Yoshino H, Japanese Circulation Society Working Group. PMID: 33597320.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    36. The usefulness of SwiftScan technology for bone scintigraphy using a novel anthropomorphic phantom. Sci Rep. 2021 01 29; 11(1):2644. Shibutani T, Onoguchi M, Naoi Y, Yoneyama H, Konishi T, Tatami R, Nakajima K. PMID: 33514818; PMCID: PMC7846574.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    37. Cardiovascular event risk estimated after coronary revascularization and optimal medical therapy: J-ACCESS4 prognostic study. Ann Nucl Med. 2021 Feb; 35(2):241-252. Sakatani T, Nakajima K, Fujita H, Nishimura T. PMID: 33389665; PMCID: PMC7895784.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    38. Responsibility of consumers for mining capacity: decomposition analysis of scarcity-weighted metal footprints in the case of Japan. iScience. 2021 Jan 22; 24(1):102025. Yokoi R, Nansai K, Nakajima K, Watari T, Motoshita M. PMID: 33490925; PMCID: PMC7809504.
      View in: PubMed   Mentions: 1  
    39. Global Metal Use Targets in Line with Climate Goals. Environ Sci Technol. 2020 10 06; 54(19):12476-12483. Watari T, Nansai K, Giurco D, Nakajima K, McLellan B, Helbig C. PMID: 32915547.
      View in: PubMed   Mentions: 9     Fields:    
    40. The Diagnostic Criteria 2020 for Triglyceride Deposit Cardiomyovasculopathy. Ann Nucl Cardiol. 2020; 6(1):99-104. Kobayashi K, Sakata Y, Miyauchi H, Ikeda Y, Nagasawa Y, Nakajima K, Shimada K, Kozawa J, Hao H, Amano T, Yoshida H, Inaba T, Hashimoto C, Hirano KI, Japan TGCV Study Group. PMID: 37123492; PMCID: PMC10133930.
      View in: PubMed   Mentions: 16  
    41. Homeostatic versus hedonic control of carbohydrate selection. J Physiol. 2020 09; 598(18):3831-3844. Minokoshi Y, Nakajima KI, Okamoto S. PMID: 32643799.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    42. Rainbow Kaposi's Sarcoma-Associated Herpesvirus Revealed Heterogenic Replication with Dynamic Gene Expression. J Virol. 2020 03 31; 94(8). Nakajima KI, Guevara-Plunkett S, Chuang F, Wang KH, Lyu Y, Kumar A, Luxardi G, Izumiya C, Soulika A, Campbell M, Izumiya Y. PMID: 31969436; PMCID: PMC7108829.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    43. The utility of heart-to-mediastinum ratio using a planar image created from IQ-SPECT with Iodine-123 meta-iodobenzylguanidine. J Nucl Cardiol. 2021 12; 28(6):2569-2577. Shibutani T, Nakajima K, Yoneyama H, Konishi T, Okuda K, Onoguchi M, Kinuya S. PMID: 32103408.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    44. Predictive value of electrocardiography-gated myocardial perfusion imaging to new-onset heart failure in patients with chronic kidney disease: findings from the J-ACCESS 3 study. Int J Cardiovasc Imaging. 2020 Apr; 36(4):749-755. Nanasato M, Matsuo S, Nakajima K, Nishimura S, Nishimura T. PMID: 32062711.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    45. Hypothalamic neuronal circuits regulating hunger-induced taste modification. Nat Commun. 2019 10 08; 10(1):4560. Fu O, Iwai Y, Narukawa M, Ishikawa AW, Ishii KK, Murata K, Yoshimura Y, Touhara K, Misaka T, Minokoshi Y, Nakajima KI. PMID: 31594935; PMCID: PMC6783447.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    46. Integrating Circular Economy Strategies with Low-Carbon Scenarios: Lithium Use in Electric Vehicles. Environ Sci Technol. 2019 Oct 15; 53(20):11657-11665. Watari T, Nansai K, Nakajima K, McLellan BC, Dominish E, Giurco D. PMID: 31577427.
      View in: PubMed   Mentions: 4     Fields:    Translation:PHPublic Health
    47. Expression of integrins to control migration direction of electrotaxis. FASEB J. 2019 08; 33(8):9131-9141. Zhu K, Takada Y, Nakajima K, Sun Y, Jiang J, Zhang Y, Zeng Q, Takada Y, Zhao M. PMID: 31116572; PMCID: PMC6662972.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    48. The difference of risk factors predicting cardiac events in patients with chronic kidney disease between with and without diabetes. Ann Nucl Med. 2019 Jul; 33(7):532-540. Okuyama C, Nakajima K, Nakamura S, Nishimura T. PMID: 31093931.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    49. SatB2-Expressing Neurons in the Parabrachial Nucleus Encode Sweet Taste. Cell Rep. 2019 05 07; 27(6):1650-1656.e4. Fu O, Iwai Y, Kondoh K, Misaka T, Minokoshi Y, Nakajima KI. PMID: 31067452.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    50. Impact of calibration methods for color medical displays on interpreting brain SPECT images. Med Phys. 2019 Jun; 46(6):2580-2588. Shibutani T, Onoguchi M, Yoneyama H, Nakajima K, Matsuo S, Bamba Y, Saito S. PMID: 30972760.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    51. Ability of artificial intelligence to diagnose coronary artery stenosis using hybrid images of coronary computed tomography angiography and myocardial perfusion SPECT. Eur J Hybrid Imaging. 2019 Mar 18; 3(1):4. Yoneyama H, Nakajima K, Taki J, Wakabayashi H, Matsuo S, Konishi T, Okuda K, Shibutani T, Onoguchi M, Kinuya S. PMID: 34191159; PMCID: PMC8212308.
      View in: PubMed   Mentions: 9  
    52. An Essential and Synergistic Role of Purinergic Signaling in Guided Migration of Corneal Epithelial Cells in Physiological Electric Fields. Cell Physiol Biochem. 2019; 52(2):198-211. Nakajima KI, Tatsumi M, Zhao M. PMID: 30816668; PMCID: PMC8917963.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    53. Global Distribution of Used and Unused Extracted Materials Induced by Consumption of Iron, Copper, and Nickel. Environ Sci Technol. 2019 02 05; 53(3):1555-1563. Nakajima K, Noda S, Nansai K, Matsubae K, Takayanagi W, Tomita M. PMID: 30596486.
      View in: PubMed   Mentions: 1     Fields:    
    54. Characteristics of iodine-123 IQ-SPECT/CT imaging compared with conventional SPECT/CT. Ann Nucl Med. 2019 Feb; 33(2):103-111. Shibutani T, Onoguchi M, Yoneyama H, Konishi T, Matsuo S, Nakajima K. PMID: 30324427.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    55. Accuracy of an artificial neural network for detecting a regional abnormality in myocardial perfusion SPECT. Ann Nucl Med. 2019 Feb; 33(2):86-92. Shibutani T, Nakajima K, Wakabayashi H, Mori H, Matsuo S, Yoneyama H, Konishi T, Okuda K, Onoguchi M, Kinuya S. PMID: 30302633.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    56. How do we establish cardiac sympathetic nervous system imaging with 123I-mIBG in clinical practice? Perspectives and lessons from Japan and the US. J Nucl Cardiol. 2019 Aug; 26(4):1434-1451. Travin MI, Matsunari I, Thomas GS, Nakajima K, Yoshinaga K. PMID: 30178272.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    57. Defective autophagy in vascular smooth muscle cells enhances cell death and atherosclerosis. Autophagy. 2018; 14(11):1991-2006. Osonoi Y, Mita T, Azuma K, Nakajima K, Masuyama A, Goto H, Nishida Y, Miyatsuka T, Fujitani Y, Koike M, Mitsumata M, Watada H. PMID: 30025494; PMCID: PMC6152523.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    58. Risk stratification based on J-ACCESS risk models with myocardial perfusion imaging: Risk versus outcomes of patients with chronic kidney disease. J Nucl Cardiol. 2020 02; 27(1):41-50. Nakajima K, Nakamura S, Hase H, Takeishi Y, Nishimura S, Kawano Y, Nishimura T. PMID: 29948890; PMCID: PMC7031191.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    59. 123I-MIBG myocardial scintigraphy for the diagnosis of DLB: a multicentre 3-year follow-up study. J Neurol Neurosurg Psychiatry. 2018 11; 89(11):1167-1173. Komatsu J, Samuraki M, Nakajima K, Arai H, Arai H, Arai T, Asada T, Fujishiro H, Hanyu H, Iizuka O, Iseki E, Kashihara K, Kosaka K, Maruno H, Mizukami K, Mizuno Y, Mori E, Nakamura H, Nakano S, Nakashima K, Nishio Y, Orimo S, Takahashi A, Taki J, Tokuda T, Urakami K, Utsumi K, Wada K, Washimi Y, Yamashina S, Yamasaki J, Yoshita M, Yamada M. PMID: 29853532.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    60. Prognostic impact of reducing myocardial ischemia identified using ECG-gated myocardial perfusion SPECT in Japanese patients with coronary artery disease: J-ACCESS 4 study. Int J Cardiol. 2018 Sep 15; 267:202-207. Nanasato M, Matsumoto N, Nakajima K, Chikamori T, Moroi M, Takehana K, Momose M, Nishina H, Kasai T, Yoda S, Kiso K, Yamamoto H, Nishimura S, Yamashina A, Kusuoka H, Hirayama A, Nishimura T. PMID: 29859707.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    61. Role of bone scan index in the prognosis and effects of therapy on prostate cancer with bone metastasis: Study design and rationale for the multicenter Prostatic Cancer Registry of Standard Hormonal and Chemotherapy Using Bone Scan Index (PROSTAT-BSI) study. Int J Urol. 2018 05; 25(5):492-499. Nakajima K, Kaneko G, Takahashi S, Matsuyama H, Shiina H, Ichikawa T, Horikoshi H, Hashine K, Sugiyama Y, Miyao T, Kamiyama M, Harada K, Ito A, Mizokami A, PROSTAT-BSI Investigators. PMID: 29633398.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    62. Prognostic value of normal stress myocardial perfusion imaging and ventricular function in Japanese patients with chronic kidney disease: a study based on the J-ACCESS-3 database. Eur J Nucl Med Mol Imaging. 2018 07; 45(7):1101-1107. Matsuo S, Nakajima K, Takeishi Y, Nishimura T. PMID: 29502312.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    63. Impact of Novel Antidepressants on Cardiac 123I-Metaiodobenzylguanidine Uptake: Experimental Studies on SK-N-SH Cells and Healthy Rabbits. J Nucl Med. 2018 07; 59(7):1099-1103. Werner RA, Kobayashi R, Javadi MS, Köck Z, Wakabayashi H, Unterecker S, Nakajima K, Lapa C, Menke A, Higuchi T. PMID: 29496989.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    64. Quercetin is a Useful Medicinal Compound Showing Various Actions Including Control of Blood Pressure, Neurite Elongation and Epithelial Ion Transport. Curr Med Chem. 2018; 25(37):4876-4887. Marunaka Y, Niisato N, Miyazaki H, Nakajima KI, Taruno A, Sun H, Marunaka R, Okui M, Yamamoto T, Kanamura N, Kogiso H, Ikeuchi Y, Kashio M, Hosogi S, Nakahari T. PMID: 27655075.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    65. Suppression of phenotype of Escherichia coli mutant defective in farnesyl diphosphate synthase by overexpression of gene for octaprenyl diphosphate synthase. Biosci Biotechnol Biochem. 2018 Jun; 82(6):1003-1010. Takahashi H, Aihara Y, Ogawa Y, Murata Y, Nakajima KI, Iida M, Shirai M, Fujisaki S. PMID: 29191106.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    66. IQ·SPECT technology and its clinical applications using multicenter normal databases. Ann Nucl Med. 2017 Nov; 31(9):649-659. Nakajima K, Okuda K, Momose M, Matsuo S, Kondo C, Sarai M, Shibutani T, Onoguchi M, Shimizu T, Vija AH. PMID: 28940141; PMCID: PMC5651712.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    67. Characteristics of single- and dual-photopeak energy window acquisitions with thallium-201 IQ-SPECT/CT system. Ann Nucl Med. 2017 Aug; 31(7):529-535. Shibutani T, Onoguchi M, Yoneyama H, Konishi T, Matsuo S, Nakajima K, Kinuya S. PMID: 28470630.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    68. Prognostic study of cardiac events in Japanese patients with chronic kidney disease using ECG-gated myocardial Perfusion imaging: Final 3-year report of the J-ACCESS 3 study. J Nucl Cardiol. 2019 04; 26(2):431-440. Nakamura S, Kawano Y, Nakajima K, Hase H, Joki N, Hatta T, Nishimura S, Moroi M, Nakagawa S, Kasai T, Kusuoka H, Takeishi Y, Momose M, Takehana K, Nanasato M, Yoda S, Nishina H, Matsumoto N, Nishimura T. PMID: 28439760; PMCID: PMC6430747.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    69. Cardiac sympathetic nervous system imaging with 123I-meta-iodobenzylguanidine: Perspectives from Japan and Europe. J Nucl Cardiol. 2017 06; 24(3):952-960. Nakajima K, Scholte AJHA, Nakata T, Dimitriu-Leen AC, Chikamori T, Vitola JV, Yoshinaga K. PMID: 28290098.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    70. A case of IgG4-related tubulointerstitial nephritis and membranous glomerulonephritis during the clinical course of gastric cancer: Imaging features of IgG4-related kidney disease. Mod Rheumatol. 2019 May; 29(3):542-546. Horita S, Fujii H, Mizushima I, Fujisawa Y, Hara S, Yamada K, Inoue D, Nakajima K, Harada K, Kawano M. PMID: 27785920.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    71. Intracellular chloride ion concentration in differentiating neuronal cell and its role in growing neurite. Biochem Biophys Res Commun. 2016 Oct 14; 479(2):338-342. Nakajima KI, Marunaka Y. PMID: 27641671.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    72. Reducing the small-heart effect in pediatric gated myocardial perfusion single-photon emission computed tomography. J Nucl Cardiol. 2017 08; 24(4):1378-1388. Yoneyama H, Nakajima K, Okuda K, Matsuo S, Onoguchi M, Kinuya S, Edenbrandt L. PMID: 27197818.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    73. Concerted action of KCNJ15/Kir4.2 and intracellular polyamines in sensing physiological electric fields for galvanotaxis. Channels (Austin). 2016 07 03; 10(4):264-6. Nakajima K, Zhao M. PMID: 26983902; PMCID: PMC4954572.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    74. Corrigendum: Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake. Nat Commun. 2016 Mar 03; 7:11019. Nakajima K, Cui Z, Li C, Meister J, Cui Y, Fu O, Smith AS, Jain S, Lowell BB, Krashes MJ, Wess J. PMID: 26936677; PMCID: PMC4782055.
      View in: PubMed   Mentions: 2     Fields:    
    75. Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake. Nat Commun. 2016 Jan 08; 7:10268. Nakajima K, Cui Z, Li C, Meister J, Cui Y, Fu O, Smith AS, Jain S, Lowell BB, Krashes MJ, Wess J. PMID: 26743492; PMCID: PMC4729878.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    76. KCNJ15/Kir4.2 couples with polyamines to sense weak extracellular electric fields in galvanotaxis. Nat Commun. 2015 Oct 09; 6:8532. Nakajima KI, Zhu K, Sun YH, Hegyi B, Zeng Q, Murphy CJ, Small JV, Chen-Izu Y, Izumiya Y, Penninger JM, Zhao M. PMID: 26449415; PMCID: PMC4603535.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansCells
    77. Elimination of scattered gamma rays from injection sites using upper offset energy windows in sentinel lymph node scintigraphy. Nucl Med Commun. 2015 May; 36(5):438-44. Yoneyama H, Tsushima H, Onoguchi M, Konishi T, Nakajima K, Kinuya S. PMID: 25695613.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    78. Diagnostic accuracy of 123I-meta-iodobenzylguanidine myocardial scintigraphy in dementia with Lewy bodies: a multicenter study. PLoS One. 2015; 10(3):e0120540. Yoshita M, Arai H, Arai H, Arai T, Asada T, Fujishiro H, Hanyu H, Iizuka O, Iseki E, Kashihara K, Kosaka K, Maruno H, Mizukami K, Mizuno Y, Mori E, Nakajima K, Nakamura H, Nakano S, Nakashima K, Nishio Y, Orimo S, Samuraki M, Takahashi A, Taki J, Tokuda T, Urakami K, Utsumi K, Wada K, Washimi Y, Yamasaki J, Yamashina S, Yamada M. PMID: 25793585; PMCID: PMC4368705.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCells
    79. The use of positron emission tomography/computed tomography imaging in radiation therapy: a phantom study for setting internal target volume of biological target volume. Radiat Oncol. 2015 Jan 08; 10:1. Kawakami W, Takemura A, Yokoyama K, Nakajima K, Yokoyama S, Koshida K. PMID: 25567003; PMCID: PMC4299814.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    80. Improved detection of sentinel lymph nodes in SPECT/CT images acquired using a low- to medium-energy general-purpose collimator. Clin Nucl Med. 2014 Jan; 39(1):e1-6. Yoneyama H, Tsushima H, Kobayashi M, Onoguchi M, Nakajima K, Kinuya S. PMID: 23603595.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    81. Rationale and design of J-ACCESS 4: prognostic impact of reducing myocardial ischemia identified using ECG-gated myocardial perfusion SPECT in Japanese patients with coronary artery disease. J Cardiol. 2014 Feb; 63(2):159-64. Nanasato M, Nakajima K, Fujita H, Zen K, Kohsaka S, Hashimoto A, Moroi M, Fukuzawa S, Chikamori T, Nishimura S, Yamashina A, Kusuoka H, Hirayama A, Nishimura T. PMID: 24012330.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    82. An inhibitor of Na(+)/H(+) exchanger (NHE), ethyl-isopropyl amiloride (EIPA), diminishes proliferation of MKN28 human gastric cancer cells by decreasing the cytosolic Cl(-) concentration via DIDS-sensitive pathways. Cell Physiol Biochem. 2012; 30(5):1241-53. Hosogi S, Miyazaki H, Nakajima K, Ashihara E, Niisato N, Kusuzaki K, Marunaka Y. PMID: 23075671.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    83. K(+)-Cl(-) cotransporter 1 (KCC1) negatively regulates NGF-induced neurite outgrowth in PC12 cells. Cell Physiol Biochem. 2012; 30(3):538-51. Nagao H, Nakajima K, Niisato N, Hirota R, Bando H, Sakaguchi H, Hisa Y, Marunaka Y. PMID: 22813581.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    84. Enhancement of tubulin polymerization by Cl(-)-induced blockade of intrinsic GTPase. Biochem Biophys Res Commun. 2012 Aug 24; 425(2):225-9. Nakajima K, Niisato N, Marunaka Y. PMID: 22828510.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    85. Spinophilin as a novel regulator of M3 muscarinic receptor-mediated insulin release in vitro and in vivo. FASEB J. 2012 Oct; 26(10):4275-86. Ruiz de Azua I, Nakajima K, Rossi M, Cui Y, Jou W, Gavrilova O, Wess J. PMID: 22730439; PMCID: PMC3448777.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    86. Regulation of epithelial sodium transport via epithelial Na+ channel. J Biomed Biotechnol. 2011; 2011:978196. Marunaka Y, Niisato N, Taruno A, Ohta M, Miyazaki H, Hosogi S, Nakajima K, Kusuzaki K, Ashihara E, Nishio K, Iwasaki Y, Nakahari T, Kubota T. PMID: 22028593; PMCID: PMC3196915.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    87. Genistein enhances the NGF-induced neurite outgrowth. Biomed Res. 2011 Oct; 32(5):351-6. Nakajima K, Niisato N, Marunaka Y. PMID: 22033305.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    88. Incremental prognostic value of myocardial perfusion single photon emission computed tomography for patients with diabetes and chronic kidney disease. Nucl Med Commun. 2011 Oct; 32(10):913-9. Okuyama C, Nakajima K, Hatta T, Nishimura S, Kusuoka H, Yamashina A, Nishimura T. PMID: 21778926.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    89. Quercetin stimulates NGF-induced neurite outgrowth in PC12 cells via activation of Na(+)/K(+)/2Cl(-) cotransporter. Cell Physiol Biochem. 2011; 28(1):147-56. Nakajima K, Niisato N, Marunaka Y. PMID: 21865857.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    90. Non-acidic compounds induce the intense sweet taste of neoculin, a taste-modifying protein. Biosci Biotechnol Biochem. 2011; 75(8):1600-2. Nakajima K, Koizumi A, Iizuka K, Ito K, Morita Y, Koizumi T, Asakura T, Shimizu-Ibuka A, Misaka T, Abe K. PMID: 21821940.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    91. NaCl flux between apical and basolateral side recruits claudin-1 to tight junction strands and regulates paracellular transport. Biochem Biophys Res Commun. 2010 Mar 12; 393(3):390-6. Tokuda S, Miyazaki H, Nakajima K, Yamada T, Marunaka Y. PMID: 20138843.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    92. pH-Dependent structural change in neoculin with special reference to its taste-modifying activity. Biosci Biotechnol Biochem. 2009 Nov; 73(11):2552-5. Morita Y, Nakajima K, Iizuka K, Terada T, Shimizu-Ibuka A, Ito K, Koizumi A, Asakura T, Misaka T, Abe K. PMID: 19897888.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    93. Hydrostatic pressure regulates tight junctions, actin cytoskeleton and transcellular ion transport. Biochem Biophys Res Commun. 2009 Dec 25; 390(4):1315-21. Tokuda S, Miyazaki H, Nakajima K, Yamada T, Marunaka Y. PMID: 19879247.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    94. Regulation of paracellular Na+ and Cl(-) conductances by hydrostatic pressure. Cell Biol Int. 2009 Sep; 33(9):949-56. Tokuda S, Niisato N, Nagai T, Taruno A, Nakajima K, Miyazaki H, Yamada T, Hosogi S, Ohta M, Nishio K, Iwasaki Y, Marunaka Y. PMID: 19524694.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    95. Quercetin stimulates Na+/K+/2Cl- cotransport via PTK-dependent mechanisms in human airway epithelium. Am J Respir Cell Mol Biol. 2009 Dec; 41(6):688-95. Asano J, Niisato N, Nakajima K, Miyazaki H, Yasuda M, Iwasaki Y, Hama T, Dejima K, Hisa Y, Marunaka Y. PMID: 19251944.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    96. Acid-induced sweetness of neoculin is ascribed to its pH-dependent agonistic-antagonistic interaction with human sweet taste receptor. FASEB J. 2008 Jul; 22(7):2323-30. Nakajima K, Morita Y, Koizumi A, Asakura T, Terada T, Ito K, Shimizu-Ibuka A, Maruyama J, Kitamoto K, Misaka T, Abe K. PMID: 18263698.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    97. Regulation of the paracellular Na+ and Cl- conductances by the NaCl-generated osmotic gradient in a manner dependent on the direction of osmotic gradients. Biochem Biophys Res Commun. 2008 Feb 08; 366(2):464-70. Tokuda S, Niisato N, Nakajima K, Marunaka Y. PMID: 18068115.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    98. Prognostic study of risk stratification among Japanese patients with ischemic heart disease using gated myocardial perfusion SPECT: J-ACCESS study. Eur J Nucl Med Mol Imaging. 2008 Feb; 35(2):319-28. Nishimura T, Nakajima K, Kusuoka H, Yamashina A, Nishimura S. PMID: 17926033.
      View in: PubMed   Mentions: 55     Fields:    
    99. Chloride-dependent acceleration of cell cycle via modulation of Rb and cdc2 in osteoblastic cells. Biochem Biophys Res Commun. 2007 Oct 05; 361(4):1038-43. Maki M, Miyazaki H, Nakajima K, Yamane J, Niisato N, Morihara T, Kubo T, Marunaka Y. PMID: 17679140.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    100. Essential role of NKCC1 in NGF-induced neurite outgrowth. Biochem Biophys Res Commun. 2007 Aug 03; 359(3):604-10. Nakajima K, Miyazaki H, Niisato N, Marunaka Y. PMID: 17548052.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    101. Action of neltenexine on anion secretion in human airway epithelia. Biochem Biophys Res Commun. 2007 May 18; 356(4):1050-5. Niisato N, Hasegawa I, Tokuda S, Taruno A, Nakajima K, Miyazaki H, Iwasaki Y, Marunaka Y. PMID: 17400191.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    102. Preparation of elastic silk sericin hydrogel. Biosci Biotechnol Biochem. 2005 Apr; 69(4):845-7. Teramoto H, Nakajima K, Takabayashi C. PMID: 15849429.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    103. Neoculin as a new taste-modifying protein occurring in the fruit of Curculigo latifolia. Biosci Biotechnol Biochem. 2004 Jun; 68(6):1403-7. Shirasuka Y, Nakajima K, Asakura T, Yamashita H, Yamamoto A, Hata S, Nagata S, Abo M, Sorimachi H, Abe K. PMID: 15215616.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    104. The Escherichia coli homologue of yeast RER2, a key enzyme of dolichol synthesis, is essential for carrier lipid formation in bacterial cell wall synthesis. J Bacteriol. 1999 May; 181(9):2733-8. Kato J, Fujisaki S, Nakajima K, Nishimura Y, Sato M, Nakano A. PMID: 10217761; PMCID: PMC93712.
      View in: PubMed   Mentions: 30     Fields:    Translation:Cells
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