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Studies on Gene Enhancer with KSHV mini-chromatin. bioRxiv. 2025 Mar 24.
Inagaki T, Kumar A, Wang KH, Komaki S, Espera JM, Bautista CSA, Nakajima KI, Izumiya C, Izumiya Y. PMID: 40196677; PMCID: PMC11974746.
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PubMed Mentions:
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Design, development, and evaluation of gene therapeutics specific to KSHV-associated diseases. bioRxiv. 2025 Feb 19.
Inagaki T, Espera J, Wang KH, Komaki S, Nair S, Davis RR, Kumar A, Nakajima KI, Izumiya Y. PMID: 40027700; PMCID: PMC11870588.
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PubMed Mentions:
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Long-term survival and durable recovery of heart failure in patients with triglyceride deposit cardiomyovasculopathy treated with tricaprin. Nat Cardiovasc Res. 2025 Mar; 4(3):266-274.
Hirano KI, Okamura S, Sugimura K, Miyauchi H, Nakano Y, Nochioka K, Hashimoto C, Iwanaga Y, Nakajima K, Yamaguchi S, Yasui Y, Shimamoto S, Hirano M, Okune M, Nishimura Y, Shimoyama H, Nagasawa Y, Amano T, Kuniyoshi S, Hui SP, Zaima N, Ikeda Y, Yamada T, Fujimoto S, Sakata Y, Kobayashi K. PMID: 39948308.
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PubMed Mentions: Translation:
HumansCells
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Ferredoxin 2 Is Critical for Tumor Suppression and Lipid Homeostasis but Dispensable for Embryonic Development. Am J Pathol. 2025 Apr; 195(4):705-716.
Zhang J, Zhang Y, Mohibi S, Perng V, Bustamante M, Shi Y, Nakajima K, Chen M, Chen X. PMID: 39732391.
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PubMed Mentions: Fields:
Translation:
Animals
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A LANA peptide inhibits tumor growth by inducing CHD4 protein cleavage and triggers cell death. Cell Chem Biol. 2024 Nov 21; 31(11):1909-1925.e7.
Miura H, Wang KH, Inagaki T, Chuang F, Shimoda M, Izumiya C, Watanabe T, Davis RR, Tepper CG, Komaki S, Nakajima KI, Kumar A, Izumiya Y. PMID: 39488208; PMCID: PMC11588034.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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An atlas of chromatin landscape in KSHV-infected cells during de novo infection and reactivation. Virology. 2024 09; 597:110146.
Inagaki T, Kumar A, Komaki S, Nakajima KI, Izumiya Y. PMID: 38909515.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Kaposi's sarcoma-associated herpesvirus (KSHV) LANA prevents KSHV episomes from degradation. J Virol. 2024 Feb 20; 98(2):e0126823.
Nakajima K-i, Inagaki T, Espera JM, Izumiya Y. PMID: 38240588; PMCID: PMC10878079.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Inhibition of high-fat diet-induced inflammatory responses in adipose tissue by SF1-expressing neurons of the ventromedial hypothalamus. Cell Rep. 2023 06 27; 42(6):112627.
Rashid M, Kondoh K, Palfalvi G, Nakajima KI, Minokoshi Y. PMID: 37339627.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Neural insights into sweet taste transduction and hunger-induced taste modification in mice. Biosci Biotechnol Biochem. 2022 Oct 20; 86(11):1485-1489.
Nakajima KI. PMID: 35998309.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4. Cell Rep. 2022 05 10; 39(6):110788.
Kumar A, Lyu Y, Yanagihashi Y, Chantarasrivong C, Majerciak V, Salemi M, Wang KH, Inagaki T, Chuang F, Davis RR, Tepper CG, Nakano K, Izumiya C, Shimoda M, Nakajima KI, Merleev A, Zheng ZM, Campbell M, Izumiya Y. PMID: 35545047; PMCID: PMC9153692.
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PubMed Mentions:
19 Fields:
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KSHV transactivator-derived small peptide traps coactivators to attenuate MYC and inhibits leukemia and lymphoma cell growth. Commun Biol. 2021 12 02; 4(1):1330.
Shimoda M, Lyu Y, Wang KH, Kumar A, Miura H, Meckler JF, Davis RR, Chantarasrivong C, Izumiya C, Tepper CG, Nakajima KI, Tuscano J, Barisone G, Izumiya Y. PMID: 34857874; PMCID: PMC8639922.
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PubMed Mentions:
5 Translation:
HumansCells
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Proximity Biotin Labeling Reveals Kaposi's Sarcoma-Associated Herpesvirus Interferon Regulatory Factor Networks. J Virol. 2021 04 12; 95(9).
Kumar A, Salemi M, Bhullar R, Guevara-Plunkett S, Lyu Y, Wang KH, Izumiya C, Campbell M, Nakajima KI, Izumiya Y. PMID: 33597212; PMCID: PMC8104114.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Rainbow Kaposi's Sarcoma-Associated Herpesvirus Revealed Heterogenic Replication with Dynamic Gene Expression. J Virol. 2020 03 31; 94(8).
Nakajima KI, Guevara-Plunkett S, Chuang F, Wang KH, Lyu Y, Kumar A, Luxardi G, Izumiya C, Soulika A, Campbell M, Izumiya Y. PMID: 31969436; PMCID: PMC7108829.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Hypothalamic neuronal circuits regulating hunger-induced taste modification. Nat Commun. 2019 10 08; 10(1):4560.
Fu O, Iwai Y, Narukawa M, Ishikawa AW, Ishii KK, Murata K, Yoshimura Y, Touhara K, Misaka T, Minokoshi Y, Nakajima KI. PMID: 31594935; PMCID: PMC6783447.
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PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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Expression of integrins to control migration direction of electrotaxis. FASEB J. 2019 08; 33(8):9131-9141.
Zhu K, Takada Y, Nakajima K, Sun Y, Jiang J, Zhang Y, Zeng Q, Takada Y, Zhao M. PMID: 31116572; PMCID: PMC6662972.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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SatB2-Expressing Neurons in the Parabrachial Nucleus Encode Sweet Taste. Cell Rep. 2019 05 07; 27(6):1650-1656.e4.
Fu O, Iwai Y, Kondoh K, Misaka T, Minokoshi Y, Nakajima KI. PMID: 31067452.
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PubMed Mentions:
26 Fields:
Translation:
AnimalsCells
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An Essential and Synergistic Role of Purinergic Signaling in Guided Migration of Corneal Epithelial Cells in Physiological Electric Fields. Cell Physiol Biochem. 2019; 52(2):198-211.
Nakajima KI, Tatsumi M, Zhao M. PMID: 30816668; PMCID: PMC8917963.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Suppression of phenotype of Escherichia coli mutant defective in farnesyl diphosphate synthase by overexpression of gene for octaprenyl diphosphate synthase. Biosci Biotechnol Biochem. 2018 Jun; 82(6):1003-1010.
Takahashi H, Aihara Y, Ogawa Y, Murata Y, Nakajima KI, Iida M, Shirai M, Fujisaki S. PMID: 29191106.
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PubMed Mentions:
4 Fields:
Translation:
Cells
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Concerted action of KCNJ15/Kir4.2 and intracellular polyamines in sensing physiological electric fields for galvanotaxis. Channels (Austin). 2016 07 03; 10(4):264-6.
Nakajima K, Zhao M. PMID: 26983902; PMCID: PMC4954572.
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PubMed Mentions:
4 Fields:
Translation:
Cells
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Corrigendum: Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake. Nat Commun. 2016 Mar 03; 7:11019.
Nakajima K, Cui Z, Li C, Meister J, Cui Y, Fu O, Smith AS, Jain S, Lowell BB, Krashes MJ, Wess J. PMID: 26936677; PMCID: PMC4782055.
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PubMed Mentions:
1 Fields:
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Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake. Nat Commun. 2016 Jan 08; 7:10268.
Nakajima K, Cui Z, Li C, Meister J, Cui Y, Fu O, Smith AS, Jain S, Lowell BB, Krashes MJ, Wess J. PMID: 26743492; PMCID: PMC4729878.
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PubMed Mentions:
47 Fields:
Translation:
HumansAnimalsCells
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KCNJ15/Kir4.2 couples with polyamines to sense weak extracellular electric fields in galvanotaxis. Nat Commun. 2015 Oct 09; 6:8532.
Nakajima KI, Zhu K, Sun YH, Hegyi B, Zeng Q, Murphy CJ, Small JV, Chen-Izu Y, Izumiya Y, Penninger JM, Zhao M. PMID: 26449415; PMCID: PMC4603535.
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PubMed Mentions:
55 Fields:
Translation:
HumansCells
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An inhibitor of Na(+)/H(+) exchanger (NHE), ethyl-isopropyl amiloride (EIPA), diminishes proliferation of MKN28 human gastric cancer cells by decreasing the cytosolic Cl(-) concentration via DIDS-sensitive pathways. Cell Physiol Biochem. 2012; 30(5):1241-53.
Hosogi S, Miyazaki H, Nakajima K, Ashihara E, Niisato N, Kusuzaki K, Marunaka Y. PMID: 23075671.
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PubMed Mentions:
26 Fields:
Translation:
HumansCells
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K(+)-Cl(-) cotransporter 1 (KCC1) negatively regulates NGF-induced neurite outgrowth in PC12 cells. Cell Physiol Biochem. 2012; 30(3):538-51.
Nagao H, Nakajima K, Niisato N, Hirota R, Bando H, Sakaguchi H, Hisa Y, Marunaka Y. PMID: 22813581.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Spinophilin as a novel regulator of M3 muscarinic receptor-mediated insulin release in vitro and in vivo. FASEB J. 2012 Oct; 26(10):4275-86.
Ruiz de Azua I, Nakajima K, Rossi M, Cui Y, Jou W, Gavrilova O, Wess J. PMID: 22730439; PMCID: PMC3448777.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Quercetin stimulates NGF-induced neurite outgrowth in PC12 cells via activation of Na(+)/K(+)/2Cl(-) cotransporter. Cell Physiol Biochem. 2011; 28(1):147-56.
Nakajima K, Niisato N, Marunaka Y. PMID: 21865857.
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PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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Non-acidic compounds induce the intense sweet taste of neoculin, a taste-modifying protein. Biosci Biotechnol Biochem. 2011; 75(8):1600-2.
Nakajima K, Koizumi A, Iizuka K, Ito K, Morita Y, Koizumi T, Asakura T, Shimizu-Ibuka A, Misaka T, Abe K. PMID: 21821940.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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pH-Dependent structural change in neoculin with special reference to its taste-modifying activity. Biosci Biotechnol Biochem. 2009 Nov; 73(11):2552-5.
Morita Y, Nakajima K, Iizuka K, Terada T, Shimizu-Ibuka A, Ito K, Koizumi A, Asakura T, Misaka T, Abe K. PMID: 19897888.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Acid-induced sweetness of neoculin is ascribed to its pH-dependent agonistic-antagonistic interaction with human sweet taste receptor. FASEB J. 2008 Jul; 22(7):2323-30.
Nakajima K, Morita Y, Koizumi A, Asakura T, Terada T, Ito K, Shimizu-Ibuka A, Maruyama J, Kitamoto K, Misaka T, Abe K. PMID: 18263698.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Preparation of elastic silk sericin hydrogel. Biosci Biotechnol Biochem. 2005 Apr; 69(4):845-7.
Teramoto H, Nakajima K, Takabayashi C. PMID: 15849429.
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PubMed Mentions:
12 Fields:
Translation:
Animals
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Neoculin as a new taste-modifying protein occurring in the fruit of Curculigo latifolia. Biosci Biotechnol Biochem. 2004 Jun; 68(6):1403-7.
Shirasuka Y, Nakajima K, Asakura T, Yamashita H, Yamamoto A, Hata S, Nagata S, Abo M, Sorimachi H, Abe K. PMID: 15215616.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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The Escherichia coli homologue of yeast RER2, a key enzyme of dolichol synthesis, is essential for carrier lipid formation in bacterial cell wall synthesis. J Bacteriol. 1999 May; 181(9):2733-8.
Kato J, Fujisaki S, Nakajima K, Nishimura Y, Sato M, Nakano A. PMID: 10217761; PMCID: PMC93712.
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PubMed Mentions:
25 Fields:
Translation:
Cells