Loading...

Jie Zheng, PhD

Title(s)Professor, Physiology And Membrane Biology
SchoolUniversity of California, Davis
vCardDownload vCard

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Yin Y, Dong Y, Vu S, Yang F, Yarov-Yarovoy V, Tian Y, Zheng J. Structural mechanisms underlying activation of TRPV1 channels by pungent compounds in gingers. Br J Pharmacol. 2019 Sep; 176(17):3364-3377. PMID: 31207668.
      View in: PubMed
    2. Dong Y, Yin Y, Vu S, Yang F, Yarov-Yarovoy V, Tian Y, Zheng J. A distinct structural mechanism underlies TRPV1 activation by piperine. Biochem Biophys Res Commun. 2019 Aug 20; 516(2):365-372. PMID: 31213294.
      View in: PubMed
    3. Yang F, Xiao X, Lee BH, Vu S, Yang W, Yarov-Yarovoy V, Zheng J. The conformational wave in capsaicin activation of transient receptor potential vanilloid 1 ion channel. Nat Commun. 2018 07 23; 9(1):2879. PMID: 30038260.
      View in: PubMed
    4. Yang F, Zheng J. Understand spiciness: mechanism of TRPV1 channel activation by capsaicin. Protein Cell. 2017 03; 8(3):169-177. PMID: 28044278.
      View in: PubMed
    5. He X, Shen C, Lu Q, Li J, Wei Y, He L, Bai R, Zheng J, Luan N, Zhang Z, Rong M, Lai R. Prokineticin 2 Plays a Pivotal Role in Psoriasis. EBioMedicine. 2016 Nov; 13:248-261. PMID: 27887936.
      View in: PubMed
    6. Kim S, Barry DM, Liu XY, Yin S, Munanairi A, Meng QT, Cheng W, Mo P, Wan L, Liu SB, Ratnayake K, Zhao ZQ, Gautam N, Zheng J, Karunarathne WK, Chen ZF. Facilitation of TRPV4 by TRPV1 is required for itch transmission in some sensory neuron populations. Sci Signal. 2016 07 19; 9(437):ra71. PMID: 27436359.
      View in: PubMed
    7. Yang F, Vu S, Yarov-Yarovoy V, Zheng J. Rational design and validation of a vanilloid-sensitive TRPV2 ion channel. Proc Natl Acad Sci U S A. 2016 06 28; 113(26):E3657-66. PMID: 27298359.
      View in: PubMed
    8. Simonov AN, Holien JK, Yeung JC, Nguyen AD, Corbin CJ, Zheng J, Kuznetsov VL, Auchus RJ, Conley AJ, Bond AM, Parker MW, Rodgers RJ, Martin LL. Mechanistic Scrutiny Identifies a Kinetic Role for Cytochrome b5 Regulation of Human Cytochrome P450c17 (CYP17A1, P450 17A1). PLoS One. 2015; 10(11):e0141252. PMID: 26587646.
      View in: PubMed
    9. Yang S, Yang F, Wei N, Hong J, Li B, Luo L, Rong M, Yarov-Yarovoy V, Zheng J, Wang K, Lai R. A pain-inducing centipede toxin targets the heat activation machinery of nociceptor TRPV1. Nat Commun. 2015 Sep 30; 6:8297. PMID: 26420335.
      View in: PubMed
    10. Lee BH, Zheng J. Proton block of proton-activated TRPV1 current. J Gen Physiol. 2015 Aug; 146(2):147-59. PMID: 26170176.
      View in: PubMed
    11. Yang F, Xiao X, Cheng W, Yang W, Yu P, Song Z, Yarov-Yarovoy V, Zheng J. Structural mechanism underlying capsaicin binding and activation of the TRPV1 ion channel. Nat Chem Biol. 2015 Jul; 11(7):518-524. PMID: 26053297.
      View in: PubMed
    12. Ma L, Lee BH, Clifton H, Schaefer S, Zheng J. Nicotinic acid is a common regulator of heat-sensing TRPV1-4 ion channels. Sci Rep. 2015 Mar 10; 5:8906. PMID: 25752528.
      View in: PubMed
    13. Clifton HL, Inceoglu B, Ma L, Zheng J, Schaefer S. TRPV1 channels are involved in niacin-induced cutaneous vasodilation in mice. J Cardiovasc Pharmacol. 2015 Feb; 65(2):184-91. PMID: 25387247.
      View in: PubMed
    14. Zheng J, Zeng X, Wang S. Calcium ion as cellular messenger. Sci China Life Sci. 2015 Jan; 58(1):1-5. PMID: 25576449.
      View in: PubMed
    15. Tang YQ, Zhou JH, Yang F, Zheng J, Wang K. The tetramerization domain potentiates Kv4 channel function by suppressing closed-state inactivation. Biophys J. 2014 Sep 02; 107(5):1090-1104. PMID: 25185545.
      View in: PubMed
    16. Yang F, Zheng J. High temperature sensitivity is intrinsic to voltage-gated potassium channels. Elife. 2014 Jul 16; 3:e03255. PMID: 25030910.
      View in: PubMed
    17. Ma L, Lee BH, Mao R, Cai A, Jia Y, Clifton H, Schaefer S, Xu L, Zheng J. Nicotinic acid activates the capsaicin receptor TRPV1: Potential mechanism for cutaneous flushing. Arterioscler Thromb Vasc Biol. 2014 Jun; 34(6):1272-80. PMID: 24675661.
      View in: PubMed
    18. Zheng J, Ma L. Structure and function of the thermoTRP channel pore. Curr Top Membr. 2014; 74:233-57. PMID: 25366239.
      View in: PubMed
    19. Yang F, Ma L, Cao X, Wang K, Zheng J. Divalent cations activate TRPV1 through promoting conformational change of the extracellular region. J Gen Physiol. 2014 Jan; 143(1):91-103. PMID: 24344245.
      View in: PubMed
    20. Cao X, Ma L, Yang F, Wang K, Zheng J. Divalent cations potentiate TRPV1 channel by lowering the heat activation threshold. J Gen Physiol. 2014 Jan; 143(1):75-90. PMID: 24344247.
      View in: PubMed
    21. Zheng J. Domain-domain interactions in ion channels. J Gen Physiol. 2013 Oct; 142(4):347-50. PMID: 24043858.
      View in: PubMed
    22. Lei L, Cao X, Yang F, Shi DJ, Tang YQ, Zheng J, Wang K. A TRPV4 channel C-terminal folding recognition domain critical for trafficking and function. J Biol Chem. 2013 Apr 12; 288(15):10427-39. PMID: 23457335.
      View in: PubMed
    23. Zheng J. Molecular mechanism of TRP channels. Compr Physiol. 2013 Jan; 3(1):221-42. PMID: 23720286.
      View in: PubMed
    24. Jin BE, Wulff H, Widdicombe JH, Zheng J, Bers DM, Puglisi JL. A simple device to illustrate the Einthoven triangle. Adv Physiol Educ. 2012 Dec; 36(4):319-24. PMID: 23209014.
      View in: PubMed
    25. Cao X, Yang F, Zheng J, Wang K. Intracellular proton-mediated activation of TRPV3 channels accounts for the exfoliation effect of a-hydroxyl acids on keratinocytes. J Biol Chem. 2012 Jul 27; 287(31):25905-16. PMID: 22679014.
      View in: PubMed
    26. Cui Y, Yang F, Cao X, Yarov-Yarovoy V, Wang K, Zheng J. Selective disruption of high sensitivity heat activation but not capsaicin activation of TRPV1 channels by pore turret mutations. J Gen Physiol. 2012 Apr; 139(4):273-83. PMID: 22412190.
      View in: PubMed
    27. Cheng W, Yang F, Liu S, Colton CK, Wang C, Cui Y, Cao X, Zhu MX, Sun C, Wang K, Zheng J. Heteromeric heat-sensitive transient receptor potential channels exhibit distinct temperature and chemical response. J Biol Chem. 2012 Mar 02; 287(10):7279-88. PMID: 22184123.
      View in: PubMed
    28. Ma L, Rychkov GY, Bykova EA, Zheng J, Bretag AH. Movement of hClC-1 C-termini during common gating and limits on their cytoplasmic location. Biochem J. 2011 Jun 01; 436(2):415-28. PMID: 21413926.
      View in: PubMed
    29. Zhang F, Liu S, Yang F, Zheng J, Wang K. Identification of a tetrameric assembly domain in the C terminus of heat-activated TRPV1 channels. J Biol Chem. 2011 Apr 29; 286(17):15308-16. PMID: 21357419.
      View in: PubMed
    30. Dong B, Cheng W, Li W, Zheng J, Wu D, Matsumura F, Vogel CF. FRET analysis of protein tyrosine kinase c-Src activation mediated via aryl hydrocarbon receptor. Biochim Biophys Acta. 2011 Apr; 1810(4):427-31. PMID: 21145940.
      View in: PubMed
    31. Cheng W, Sun C, Zheng J. Heteromerization of TRP channel subunits: extending functional diversity. Protein Cell. 2010 Sep; 1(9):802-10. PMID: 21203922.
      View in: PubMed
    32. Yang F, Cui Y, Wang K, Zheng J. Thermosensitive TRP channel pore turret is part of the temperature activation pathway. Proc Natl Acad Sci U S A. 2010 Apr 13; 107(15):7083-8. PMID: 20351268.
      View in: PubMed
    33. Praporski S, Ng SM, Nguyen AD, Corbin CJ, Mechler A, Zheng J, Conley AJ, Martin LL. Organization of cytochrome P450 enzymes involved in sex steroid synthesis: PROTEIN-PROTEIN INTERACTIONS IN LIPID MEMBRANES. J Biol Chem. 2009 Nov 27; 284(48):33224-32. PMID: 19805543.
      View in: PubMed
    34. Qiu S, Zhang XM, Cao JY, Yang W, Yan YG, Shan L, Zheng J, Luo JH. An endoplasmic reticulum retention signal located in the extracellular amino-terminal domain of the NR2A subunit of N-Methyl-D-aspartate receptors. J Biol Chem. 2009 Jul 24; 284(30):20285-98. PMID: 19487695.
      View in: PubMed
    35. Sun P, Wang J, Gu W, Cheng W, Jin GZ, Friedman E, Zheng J, Zhen X. PSD-95 regulates D1 dopamine receptor resensitization, but not receptor-mediated Gs-protein activation. Cell Res. 2009 May; 19(5):612-24. PMID: 19274064.
      View in: PubMed
    36. Qu Z, Cheng W, Cui Y, Cui Y, Zheng J. Human disease-causing mutations disrupt an N-C-terminal interaction and channel function of bestrophin 1. J Biol Chem. 2009 Jun 12; 284(24):16473-81. PMID: 19372599.
      View in: PubMed
    37. Liang S, Yang F, Zhou C, Wang Y, Li S, Sun CK, Puglisi JL, Bers D, Sun C, Zheng J. Temperature-dependent activation of neurons by continuous near-infrared laser. Cell Biochem Biophys. 2009; 53(1):33-42. PMID: 19034696.
      View in: PubMed
    38. Vetter I, Cheng W, Peiris M, Wyse BD, Roberts-Thomson SJ, Zheng J, Monteith GR, Cabot PJ. Rapid, opioid-sensitive mechanisms involved in transient receptor potential vanilloid 1 sensitization. J Biol Chem. 2008 Jul 11; 283(28):19540-50. PMID: 18482991.
      View in: PubMed
    39. Gao Y, Liu SS, Qiu S, Cheng W, Zheng J, Luo JH. Fluorescence resonance energy transfer analysis of subunit assembly of the ASIC channel. Biochem Biophys Res Commun. 2007 Jul 20; 359(1):143-50. PMID: 17532298.
      View in: PubMed
    40. Cheng W, Yang F, Takanishi CL, Zheng J. Thermosensitive TRPV channel subunits coassemble into heteromeric channels with intermediate conductance and gating properties. J Gen Physiol. 2007 Mar; 129(3):191-207. PMID: 17325193.
      View in: PubMed
    41. Bykova EA, Zhang XD, Chen TY, Zheng J. Large movement in the C terminus of CLC-0 chloride channel during slow gating. Nat Struct Mol Biol. 2006 Dec; 13(12):1115-9. PMID: 17115052.
      View in: PubMed
    42. Takanishi CL, Bykova EA, Cheng W, Zheng J. GFP-based FRET analysis in live cells. Brain Res. 2006 May 26; 1091(1):132-9. PMID: 16529720.
      View in: PubMed
    43. Zheng J. Patch fluorometry: shedding new light on ion channels. Physiology (Bethesda). 2006 Feb; 21:6-12. PMID: 16443817.
      View in: PubMed
    44. Zheng J. Spectroscopy-based quantitative fluorescence resonance energy transfer analysis. Methods Mol Biol. 2006; 337:65-77. PMID: 16929939.
      View in: PubMed
    45. Zheng J, Zagotta WN. Stoichiometry and assembly of olfactory cyclic nucleotide-gated channels. Neuron. 2004 May 13; 42(3):411-21. PMID: 15134638.
      View in: PubMed
    46. Zheng J, Varnum MD, Zagotta WN. Disruption of an intersubunit interaction underlies Ca2+-calmodulin modulation of cyclic nucleotide-gated channels. J Neurosci. 2003 Sep 03; 23(22):8167-75. PMID: 12954880.
      View in: PubMed
    47. Zheng J, Zagotta WN. Patch-clamp fluorometry recording of conformational rearrangements of ion channels. Sci STKE. 2003 Apr 01; 2003(176):PL7. PMID: 12671191.
      View in: PubMed
    48. Zheng J, Trudeau MC, Zagotta WN. Rod cyclic nucleotide-gated channels have a stoichiometry of three CNGA1 subunits and one CNGB1 subunit. Neuron. 2002 Dec 05; 36(5):891-6. PMID: 12467592.
      View in: PubMed
    49. Zheng J, Vankataramanan L, Sigworth FJ. Hidden Markov model analysis of intermediate gating steps associated with the pore gate of shaker potassium channels. J Gen Physiol. 2001 Nov; 118(5):547-64. PMID: 11696611.
      View in: PubMed
    50. Zheng J, Zagotta WN. Gating rearrangements in cyclic nucleotide-gated channels revealed by patch-clamp fluorometry. Neuron. 2000 Nov; 28(2):369-74. PMID: 11144348.
      View in: PubMed
    51. Zheng J, Sigworth FJ. Intermediate conductances during deactivation of heteromultimeric Shaker potassium channels. J Gen Physiol. 1998 Oct; 112(4):457-74. PMID: 9758864.
      View in: PubMed
    52. Zheng J, Sigworth FJ. Selectivity changes during activation of mutant Shaker potassium channels. J Gen Physiol. 1997 Aug; 110(2):101-17. PMID: 9236204.
      View in: PubMed
    53. Mathur R, Zheng J, Yan Y, Sigworth FJ. Role of the S3-S4 linker in Shaker potassium channel activation. J Gen Physiol. 1997 Feb; 109(2):191-9. PMID: 9041448.
      View in: PubMed