Jonathan Widdicombe

InstitutionUniversity of California Davis
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    1. Widdicombe J, Wine JJ. Airway Gland Structure and Function. Physiol Rev. 2015 Oct; 95(4):1241-319. PMID: 26336032.
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    2. Hajighasemi-Ossareh M, Borthwell RM, Lachowicz-Scroggins M, Stevens JE, Finkbeiner WE, Widdicombe J. Distribution and size of mucous glands in the ferret tracheobronchial tree. Anat Rec (Hoboken). 2013 Nov; 296(11):1768-74. PMID: 24106034; PMCID: PMC4096109.
    3. Jin BE, Wulff H, Widdicombe J, Zheng J, Bers DM, Puglisi JL. A simple device to illustrate the Einthoven triangle. Adv Physiol Educ. 2012 Dec; 36(4):319-24. PMID: 23209014; PMCID: PMC3776430.
    4. Finkbeiner WE, Zlock LT, Morikawa M, Lao AY, Dasari V, Widdicombe J. Cystic fibrosis and the relationship between mucin and chloride secretion by cultures of human airway gland mucous cells. Am J Physiol Lung Cell Mol Physiol. 2011 Oct; 301(4):L402-14. PMID: 21724859; PMCID: PMC3191753.
    5. Sachs LA, Schnurr D, Yagi S, Lachowicz-Scroggins ME, Widdicombe J. Quantitative real-time PCR for rhinovirus, and its use in determining the relationship between TCID50 and the number of viral particles. J Virol Methods. 2011 Jan; 171(1):212-8. PMID: 21070809.
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    6. Widdicombe J. Transgenic animals may help resolve a sticky situation in cystic fibrosis. J Clin Invest. 2010 Sep; 120(9):3093-6. PMID: 20739746; PMCID: PMC2929743.
    7. Fischer H, Illek B, Sachs L, Finkbeiner WE, Widdicombe J. CFTR and calcium-activated chloride channels in primary cultures of human airway gland cells of serous or mucous phenotype. Am J Physiol Lung Cell Mol Physiol. 2010 Oct; 299(4):L585-94. PMID: 20675434; PMCID: PMC2957417.
    8. Lachowicz-Scroggins ME, Boushey HA, Finkbeiner WE, Widdicombe J. Interleukin-13-induced mucous metaplasia increases susceptibility of human airway epithelium to rhinovirus infection. Am J Respir Cell Mol Biol. 2010 Dec; 43(6):652-61. PMID: 20081054; PMCID: PMC2993086.
    9. Finkbeiner WE, Zlock LT, Mehdi I, Widdicombe J. Cultures of human tracheal gland cells of mucous or serous phenotype. In Vitro Cell Dev Biol Anim. 2010 May; 46(5):450-6. PMID: 19998060; PMCID: PMC2862963.
    10. Lopez-Souza N, Favoreto S, Wong H, Ward T, Yagi S, Schnurr D, Finkbeiner WE, Dolganov GM, Widdicombe J, Boushey HA, Avila PC. In vitro susceptibility to rhinovirus infection is greater for bronchial than for nasal airway epithelial cells in human subjects. J Allergy Clin Immunol. 2009 Jun; 123(6):1384-90.e2. PMID: 19428098; PMCID: PMC2744461.
    11. Fischer H, Illek B, Finkbeiner WE, Widdicombe J. Basolateral Cl channels in primary airway epithelial cultures. Am J Physiol Lung Cell Mol Physiol. 2007 Jun; 292(6):L1432-43. PMID: 17322286.
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    12. Maurisse R, Cheung J, Widdicombe J, Gruenert DC. Modification of the pig CFTR gene mediated by small fragment homologous replacement. Ann N Y Acad Sci. 2006 Oct; 1082:120-3. PMID: 17145933.
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    13. Wilson M, Widdicombe J, Gohil K, Burtis KC, Reznick AZ, Cross CE, Eiserich JP. Are Drosophila a useful model for understanding the toxicity of inhaled oxidative pollutants: a review. Inhal Toxicol. 2005 Dec 01; 17(13):765-74. PMID: 16195212.
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    14. Tseng J, Do J, Widdicombe J, Machen TE. Innate immune responses of human tracheal epithelium to Pseudomonas aeruginosa flagellin, TNF-alpha, and IL-1beta. Am J Physiol Cell Physiol. 2006 Mar; 290(3):C678-90. PMID: 16251478.
      View in: PubMed
    15. Widdicombe J, Sachs LA, Morrow JL, Finkbeiner WE. Expansion of cultures of human tracheal epithelium with maintenance of differentiated structure and function. Biotechniques. 2005 Aug; 39(2):249-55. PMID: 16116798.
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    16. Serikov VB, Choi H, Schmiel K, Skaggs C, Fleming NW, Wu R, Widdicombe J. Endotoxin induces leukocyte transmigration and changes in permeability of the airway epithelium via protein-kinase C and extracellular regulated kinase activation. J Endotoxin Res. 2004; 10(1):55-65. PMID: 15025824.
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    17. Serikov VB, Choi H, Chmiel KJ, Wu R, Widdicombe J. Activation of extracellular regulated kinases is required for the increase in airway epithelial permeability during leukocyte transmigration. Am J Respir Cell Mol Biol. 2004 Mar; 30(3):261-70. PMID: 12842851.
      View in: PubMed
    18. Lopez-Souza N, Avila PC, Widdicombe J. Polarized cultures of human airway epithelium from nasal scrapings and bronchial brushings. In Vitro Cell Dev Biol Anim. 2003 Jul-Aug; 39(7):266-9. PMID: 14531727.
      View in: PubMed
    19. Fischer H, Widdicombe J, Illek B. Acid secretion and proton conductance in human airway epithelium. Am J Physiol Cell Physiol. 2002 Apr; 282(4):C736-43. PMID: 11880261.
      View in: PubMed
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