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A Brief History of Bronchitis in England and Wales. Chronic Obstr Pulm Dis. 2020 Oct; 7(4):303-314.
Widdicombe JH. PMID: 32989942; PMCID: PMC7883910.
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PubMed Mentions:
2
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Why Airway Gland Secretions Are Abnormally Sticky in Cystic Fibrosis, and Why Not Much Can Be Done About It. Dev Cell. 2020 08 24; 54(4):427-428.
Widdicombe JH. PMID: 32841592.
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PubMed Mentions: Fields:
Translation:
Humans
-
Early studies on the surface epithelium of mammalian airways. Am J Physiol Lung Cell Mol Physiol. 2019 10 01; 317(4):L486-L495.
Widdicombe JH. PMID: 31313615.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Early studies of airway submucosal glands. Am J Physiol Lung Cell Mol Physiol. 2019 06 01; 316(6):L990-L998.
Widdicombe JH. PMID: 30864819.
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PubMed Mentions:
3 Fields:
Translation:
Humans
-
Airway Gland Structure and Function. Physiol Rev. 2015 Oct; 95(4):1241-319.
Widdicombe JH, Wine JJ. PMID: 26336032.
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PubMed Mentions:
86 Fields:
Translation:
HumansAnimals
-
Chapter 7 Development of Salt and Water Transport across Airway and Alveolar Epithelia. . 2014 Jan 1; 137-155.
Widdicombe WJ. .
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Publisher Site Mentions:
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Distribution and size of mucous glands in the ferret tracheobronchial tree. Anat Rec (Hoboken). 2013 Nov; 296(11):1768-74.
Hajighasemi-Ossareh M, Borthwell RM, Lachowicz-Scroggins M, Stevens JE, Finkbeiner WE, Widdicombe JH. PMID: 24106034; PMCID: PMC4096109.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
-
A simple device to illustrate the Einthoven triangle. Adv Physiol Educ. 2012 Dec; 36(4):319-24.
Jin BE, Wulff H, Widdicombe JH, Zheng J, Bers DM, Puglisi JL. PMID: 23209014; PMCID: PMC3776430.
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PubMed Mentions:
4 Fields:
Translation:
Humans
-
Differential effects of extracellular ATP on chloride transport in cortical collecting duct cells. Am J Physiol Renal Physiol. 2012 Aug 15; 303(4):F483-91.
Rajagopal M, Kathpalia PP, Widdicombe JH, Pao AC. PMID: 22647633; PMCID: PMC3423110.
View in:
PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
-
Chloride secretion by cultures of pig tracheal gland cells. Am J Physiol Lung Cell Mol Physiol. 2012 May 15; 302(10):L1098-106.
Widdicombe JH, Borthwell RM, Hajighasemi-Ossareh M, Lachowicz-Scroggins ME, Finkbeiner WE, Stevens JE, Modlin S. PMID: 22367783; PMCID: PMC3362257.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Cystic fibrosis and the relationship between mucin and chloride secretion by cultures of human airway gland mucous cells. Am J Physiol Lung Cell Mol Physiol. 2011 Oct; 301(4):L402-14.
Finkbeiner WE, Zlock LT, Morikawa M, Lao AY, Dasari V, Widdicombe JH. PMID: 21724859; PMCID: PMC3191753.
View in:
PubMed Mentions:
19 Fields:
Translation:
Humans
-
Quantitative real-time PCR for rhinovirus, and its use in determining the relationship between TCID50 and the number of viral particles. J Virol Methods. 2011 Jan; 171(1):212-8.
Sachs LA, Schnurr D, Yagi S, Lachowicz-Scroggins ME, Widdicombe JH. PMID: 21070809.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Transgenic animals may help resolve a sticky situation in cystic fibrosis. J Clin Invest. 2010 Sep; 120(9):3093-6.
Widdicombe JH. PMID: 20739746; PMCID: PMC2929743.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
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CFTR and calcium-activated chloride channels in primary cultures of human airway gland cells of serous or mucous phenotype. Am J Physiol Lung Cell Mol Physiol. 2010 Oct; 299(4):L585-94.
Fischer H, Illek B, Sachs L, Finkbeiner WE, Widdicombe JH. PMID: 20675434; PMCID: PMC2957417.
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PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Interleukin-13-induced mucous metaplasia increases susceptibility of human airway epithelium to rhinovirus infection. Am J Respir Cell Mol Biol. 2010 Dec; 43(6):652-61.
Lachowicz-Scroggins ME, Boushey HA, Finkbeiner WE, Widdicombe JH. PMID: 20081054; PMCID: PMC2993086.
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PubMed Mentions:
59 Fields:
Translation:
HumansCells
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Cultures of human tracheal gland cells of mucous or serous phenotype. In Vitro Cell Dev Biol Anim. 2010 May; 46(5):450-6.
Finkbeiner WE, Zlock LT, Mehdi I, Widdicombe JH. PMID: 19998060; PMCID: PMC2862963.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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In vitro susceptibility to rhinovirus infection is greater for bronchial than for nasal airway epithelial cells in human subjects. J Allergy Clin Immunol. 2009 Jun; 123(6):1384-90.e2.
Lopez-Souza N, Favoreto S, Wong H, Ward T, Yagi S, Schnurr D, Finkbeiner WE, Dolganov GM, Widdicombe JH, Boushey HA, Avila PC. PMID: 19428098; PMCID: PMC2744461.
View in:
PubMed Mentions:
100 Fields:
Translation:
HumansCells
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Hormonal and purinergic stimulation of bicarbonate secretion in oviducts of rhesus monkey. Am J Physiol Endocrinol Metab. 2008 Jul; 295(1):E55-62.
Rajagopal M, Fischer H, Widdicombe JH. PMID: 18430967.
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PubMed Mentions:
7 Fields:
Translation:
Animals
-
Basolateral Cl channels in primary airway epithelial cultures. Am J Physiol Lung Cell Mol Physiol. 2007 Jun; 292(6):L1432-43.
Fischer H, Illek B, Finkbeiner WE, Widdicombe JH. PMID: 17322286.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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Mechanisms of acid and base secretion by the airway epithelium. J Membr Biol. 2006; 211(3):139-50.
Fischer H, Widdicombe JH. PMID: 17091214; PMCID: PMC2929530.
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PubMed Mentions:
107 Fields:
Translation:
HumansAnimals
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Modification of the pig CFTR gene mediated by small fragment homologous replacement. Ann N Y Acad Sci. 2006 Oct; 1082:120-3.
Maurisse R, Cheung J, Widdicombe J, Gruenert DC. PMID: 17145933.
View in:
PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
-
Differentiated structure and function of primary cultures of monkey oviductal epithelium. In Vitro Cell Dev Biol Anim. 2006 Sep-Oct; 42(8-9):248-54.
Rajagopal M, Tollner TL, Finkbeiner WE, Cherr GN, Widdicombe JH. PMID: 17163779.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
-
Are Drosophila a useful model for understanding the toxicity of inhaled oxidative pollutants: a review. Inhal Toxicol. 2005 Dec 01; 17(13):765-74.
Wilson M, Widdicombe JH, Gohil K, Burtis KC, Reznick AZ, Cross CE, Eiserich JP. PMID: 16195212.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsPHPublic Health
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Innate immune responses of human tracheal epithelium to Pseudomonas aeruginosa flagellin, TNF-alpha, and IL-1beta. Am J Physiol Cell Physiol. 2006 Mar; 290(3):C678-90.
Tseng J, Do J, Widdicombe JH, Machen TE. PMID: 16251478.
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PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Expansion of cultures of human tracheal epithelium with maintenance of differentiated structure and function. Biotechniques. 2005 Aug; 39(2):249-55.
Widdicombe JH, Sachs LA, Morrow JL, Finkbeiner WE. PMID: 16116798.
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PubMed Mentions:
21 Fields:
Translation:
HumansCells
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Inositol polyphosphate derivative inhibits Na+ transport and improves fluid dynamics in cystic fibrosis airway epithelia. Am J Physiol Cell Physiol. 2005 Sep; 289(3):C512-20.
Moody M, Pennington C, Schultz C, Caldwell R, Dinkel C, Rossi MW, McNamara S, Widdicombe J, Gabriel S, Traynor-Kaplan AE. PMID: 15857902; PMCID: PMC1800890.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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A novel extract SB-300 from the stem bark latex of Croton lechleri inhibits CFTR-mediated chloride secretion in human colonic epithelial cells. J Ethnopharmacol. 2004 Aug; 93(2-3):351-7.
Fischer H, Machen TE, Widdicombe JH, Carlson TJ, King SR, Chow JW, Illek B. PMID: 15234776.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Secretion of lactoferrin and lysozyme by cultures of human airway epithelium. Am J Physiol Lung Cell Mol Physiol. 2004 Apr; 286(4):L750-5.
Dubin RF, Robinson SK, Widdicombe JH. PMID: 15003937.
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PubMed Mentions:
38 Fields:
Translation:
HumansCells
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Resistance of differentiated human airway epithelium to infection by rhinovirus. Am J Physiol Lung Cell Mol Physiol. 2004 Feb; 286(2):L373-81.
Lopez-Souza N, Dolganov G, Dubin R, Sachs LA, Sassina L, Sporer H, Yagi S, Schnurr D, Boushey HA, Widdicombe JH. PMID: 14711802.
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PubMed Mentions:
57 Fields:
Translation:
HumansCells
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Chapter 8 Development of Fluid Transport Pulmonary Epithelia. . 2004 Jan 1; (Physiol. Rev.671987):119-129.
Widdicombe WJ. .
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Publisher Site Mentions:
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Endotoxin induces leukocyte transmigration and changes in permeability of the airway epithelium via protein-kinase C and extracellular regulated kinase activation. J Endotoxin Res. 2004; 10(1):55-65.
Serikov VB, Choi H, Schmiel K, Skaggs C, Fleming NW, Wu R, Widdicombe JH. PMID: 15025824.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
-
Activation of extracellular regulated kinases is required for the increase in airway epithelial permeability during leukocyte transmigration. Am J Respir Cell Mol Biol. 2004 Mar; 30(3):261-70.
Serikov VB, Choi H, Chmiel KJ, Wu R, Widdicombe JH. PMID: 12842851.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Polarized cultures of human airway epithelium from nasal scrapings and bronchial brushings. In Vitro Cell Dev Biol Anim. 2003 Jul-Aug; 39(7):266-9.
Lopez-Souza N, Avila PC, Widdicombe JH. PMID: 14531727.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Measurement of nasal potential difference in mild asthmatics. Chest. 2003 May; 123(5):1467-71.
Chung NC, Illek B, Widdicombe JH, Fischer H. PMID: 12740262.
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PubMed Mentions:
2 Fields:
Translation:
Humans
-
Effects of growth surface on differentiation of cultures of human tracheal epithelium. In Vitro Cell Dev Biol Anim. 2003 Jan-Feb; 39(1-2):51-5.
Widdicombe JH, Sachs LA, Finkbeiner WE. PMID: 12892527.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Effects of media on differentiation of cultured human tracheal epithelium. In Vitro Cell Dev Biol Anim. 2003 Jan-Feb; 39(1-2):56-62.
Sachs LA, Finkbeiner WE, Widdicombe JH. PMID: 12892528.
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PubMed Mentions:
39 Fields:
Translation:
HumansAnimalsCells
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Regulation of the depth and composition of airway surface liquid. J Anat. 2002 Oct; 201(4):313-8.
Widdicombe JH. PMID: 12430955; PMCID: PMC1570918.
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PubMed Mentions:
64 Fields:
Translation:
Animals
-
Distribution and numbers of mucous glands in the horse trachea. Equine Vet J. 2002 Sep; 34(6):630-3.
Widdicombe JH, Pecson IS. PMID: 12358006.
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PubMed Mentions:
5 Fields:
Translation:
Animals
-
Volume of airway surface liquid in health and disease. Am J Respir Crit Care Med. 2002 Jun 01; 165(11):1566.
Widdicombe JH. PMID: 12045135.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
-
Acid secretion and proton conductance in human airway epithelium. Am J Physiol Cell Physiol. 2002 Apr; 282(4):C736-43.
Fischer H, Widdicombe JH, Illek B. PMID: 11880261.
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PubMed Mentions:
44 Fields:
Translation:
HumansCells
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Estimate of the subepithelial hydrostatic pressure that drives inflammatory transudate into the airway lumen. J Appl Physiol (1985). 2002 Apr; 92(4):1702-8.
Serikov VB, Jang YJ, Widdicombe JH. PMID: 11896040.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
-
Alveolar epithelial type I cells contain transport proteins and transport sodium, supporting an active role for type I cells in regulation of lung liquid homeostasis. Proc Natl Acad Sci U S A. 2002 Feb 19; 99(4):1966-71.
Johnson MD, Widdicombe JH, Allen L, Barbry P, Dobbs LG. PMID: 11842214; PMCID: PMC122303.
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PubMed Mentions:
94 Fields:
Translation:
AnimalsCells
-
Altered NaCl concentration of airway surface liquid in cystic fibrosis. Pflugers Arch. 2001; 443 Suppl 1:S8-10.
Widdicombe JH. PMID: 11845295.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Distribution of tracheal and laryngeal mucous glands in some rodents and the rabbit. J Anat. 2001 Feb; 198(Pt 2):207-21.
Widdicombe JH, Chen LL, Sporer H, Choi HK, Pecson IS, Bastacky SJ. PMID: 11273045; PMCID: PMC1468211.
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PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
-
A comparative study of mammalian tracheal mucous glands. J Anat. 2000 Oct; 197 Pt 3:361-72.
Choi HK, Finkbeiner WE, Widdicombe JH. PMID: 11117623; PMCID: PMC1468138.
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PubMed Mentions:
49 Fields:
Translation:
HumansAnimals
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Yet another role for the cystic fibrosis transmembrane conductance regulator. Am J Respir Cell Mol Biol. 2000 Jan; 22(1):11-4.
Widdicombe JH. PMID: 10615060.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
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Restoration of cyclic adenosine monophosphate-stimulated chloride channel activity in human cystic fibrosis tracheobronchial submucosal gland cells by adenovirus-mediated and cationic lipid-mediated gene transfer. Am J Respir Cell Mol Biol. 1999 Jun; 20(6):1107-15.
Jiang C, Finkbeiner WE, Widdicombe JH, Fang SL, Wang KX, Nietupski JB, Hehir KM, Cheng SH. PMID: 10340929.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
Altered NaCl Concentration of Airway Surface Liquid in Cystic Fibrosis. News Physiol Sci. 1999 Jun; 14:126-127.
Widdicombe JH. PMID: 11390837.
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PubMed Mentions:
5 Fields:
-
Hepatocyte growth factor inhibits amiloride-sensitive Na(+) channel function in cystic fibrosis airway epithelium in vitro. Pulm Pharmacol Ther. 1999; 12(3):157-64.
Shen BQ, Widdicomb JH, Mrsny RJ. PMID: 10419835.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
cAMP-dependent absorption of chloride across airway epithelium. Am J Physiol. 1998 12; 275(6):L1219-27.
Uyekubo SN, Fischer H, Maminishkis A, Illek B, Miller SS, Widdicombe JH. PMID: 9843860.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Pseudomonas aeruginosa induces changes in fluid transport across airway surface epithelia. Am J Physiol. 1998 11; 275(5):C1284-90.
Evans DJ, Matsumoto PS, Widdicombe JH, Li-Yun C, Maminishkis AA, Miller SS. PMID: 9814977.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
-
Loss of CFTR chloride channels alters salt absorption by cystic fibrosis airway epithelia in vitro. Mol Cell. 1998 Sep; 2(3):397-403.
Zabner J, Smith JJ, Karp PH, Widdicombe JH, Welsh MJ. PMID: 9774978.
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PubMed Mentions:
78 Fields:
Translation:
HumansCells
-
Efficient expression of CFTR function with adeno-associated virus vectors that carry shortened CFTR genes. Proc Natl Acad Sci U S A. 1998 Aug 18; 95(17):10158-63.
Zhang L, Wang D, Fischer H, Fan PD, Widdicombe JH, Kan YW, Dong JY. PMID: 9707617; PMCID: PMC21478.
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PubMed Mentions:
25 Fields:
Translation:
HumansCells
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Evidence that Calu-3 human airway cells secrete bicarbonate. Am J Physiol. 1998 03; 274(3):L450-3.
Lee MC, Penland CM, Widdicombe JH, Wine JJ. PMID: 9530182.
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PubMed Mentions:
27 Fields:
Translation:
HumansCells
-
Regulation of the depth of surface liquid in bovine trachea. Am J Physiol. 1998 03; 274(3):L388-95.
Wu DX, Lee CY, Uyekubo SN, Choi HK, Bastacky SJ, Widdicombe JH. PMID: 9530174.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
-
Regulation of depth and composition of airway surface liquid. Eur Respir J. 1997 Dec; 10(12):2892-7.
Widdicombe JH, Bastacky SJ, Wu DX, Lee CY. PMID: 9493680.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimals
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Cultured lung epithelium: A cellular model for lung preservation. Cryobiology. 1997 Nov; 35(3):209-18.
Lee CY, Matsumoto-Pon J, Widdicombe JH. PMID: 9367609.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Structural cues involved in endoplasmic reticulum degradation of G85E and G91R mutant cystic fibrosis transmembrane conductance regulator. J Clin Invest. 1997 Sep 01; 100(5):1079-88.
Xiong X, Bragin A, Widdicombe JH, Cohn J, Skach WR. PMID: 9276724; PMCID: PMC508282.
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PubMed Mentions:
26 Fields:
Translation:
AnimalsCells
-
Fluid transport across cultures of human tracheal glands is altered in cystic fibrosis. J Physiol. 1997 Jun 15; 501 ( Pt 3):637-47.
Jiang C, Finkbeiner WE, Widdicombe JH, Miller SS. PMID: 9218222; PMCID: PMC1159463.
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PubMed Mentions:
16 Fields:
Translation:
HumansCells
-
Hepatocyte growth factor stimulates the differentiation of human tracheal epithelia in vitro. Am J Physiol. 1997 Jun; 272(6 Pt 1):L1115-20.
Shen BQ, Panos RJ, Hansen-Guzmán K, Widdicombe JH, Mrsny RJ. PMID: 9227512.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Effects of hydrostatic pressure on permeability of airway epithelium. Exp Lung Res. 1997 May-Jun; 23(3):257-67.
Azizi F, Matsumoto PS, Wu DX, Widdicombe JH. PMID: 9184792.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
-
Ultrastructure of tracheal surface liquid: low-temperature scanning electron microscopy. Scanning. 1996 Nov; 18(8):589-92.
Wu DX, Lee CY, Widdicombe JH, Bastacky J. PMID: 8946773.
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PubMed Mentions:
1 Fields:
Translation:
Animals
-
Transient permeabilization of airway epithelium by mucosal water. J Appl Physiol (1985). 1996 Jul; 81(1):491-9.
Widdicombe JH, Azizi F, Kang T, Pittet JF. PMID: 8828701.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Intraluminal water increases expression of plasmid DNA in rat lung. Hum Gene Ther. 1996 May 20; 7(8):933-41.
Sawa T, Miyazaki H, Pittet JF, Widdicombe JH, Gropper MA, Hashimoto S, Conrad DJ, Folkesson HG, Debs R, Forsayeth JR, Fox B, Wiener-Kronish JP. PMID: 8727507.
View in:
PubMed Mentions:
6 Fields:
Translation:
Animals
-
Role of CFTR in chloride secretion across human tracheal epithelium. Am J Physiol. 1995 Nov; 269(5 Pt 1):L561-6.
Shen BQ, Mrsny RJ, Finkbeiner WE, Widdicombe JH. PMID: 7491973.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
-
Effects of lovastatin on trafficking of cystic fibrosis transmembrane conductance regulator in human tracheal epithelium. J Biol Chem. 1995 Oct 20; 270(42):25102-6.
Shen BQ, Widdicombe JH, Mrsny RJ. PMID: 7559642.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
cAMP-independent activation of CFTR Cl channels by the tyrosine kinase inhibitor genistein. Am J Physiol. 1995 Apr; 268(4 Pt 1):C886-93.
Illek B, Fischer H, Santos GF, Widdicombe JH, Machen TE, Reenstra WW. PMID: 7537452.
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PubMed Mentions:
56 Fields:
Translation:
AnimalsCells
-
A method for measuring Cl efflux from dispersed cells of airway epithelium. J Appl Physiol (1985). 1995 Mar; 78(3):1197-202.
Ohrui T, Shen BQ, Mrsny RJ, Widdicombe JH. PMID: 7539784.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Culture and transformation of human airway epithelial cells. Am J Physiol. 1995 Mar; 268(3 Pt 1):L347-60.
Gruenert DC, Finkbeiner WE, Widdicombe JH. PMID: 7900815.
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PubMed Mentions:
121 Fields:
Translation:
HumansAnimalsCells
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Regulation of human airway surface liquid. Respir Physiol. 1995 Jan; 99(1):3-12.
Widdicombe JH, Widdicombe JG. PMID: 7740210.
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PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
-
Serial propagation of cells from human tracheobronchial glands. In Vitro Cell Dev Biol Anim. 1994 Dec; 30A(12):817-8.
Finbeiner WE, Widdicombe JH. PMID: 7894771.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Accumulation of airway mucus in cystic fibrosis. Pulm Pharmacol. 1994 Aug; 7(4):225-33.
Widdicombe JH. PMID: 7620238.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
-
Chloride secretion and function of serous and mucous cells of human airway glands. Am J Physiol. 1994 Aug; 267(2 Pt 1):L206-10.
Finkbeiner WE, Shen BQ, Widdicombe JH. PMID: 7521139.
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PubMed Mentions:
10 Fields:
Translation:
Humans
-
Radiotracer studies of cystic fibrosis transmembrane conductance regulator expressed in Xenopus oocytes. Am J Physiol. 1994 Jun; 266(6 Pt 1):C1586-93.
Ohrui T, Skach W, Thompson M, Matsumoto-Pon J, Calayag C, Widdicombe JH. PMID: 7517633.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
-
CFTR in Calu-3 human airway cells: channel properties and role in cAMP-activated Cl- conductance. Am J Physiol. 1994 May; 266(5 Pt 1):L502-12.
Haws C, Finkbeiner WE, Widdicombe JH, Wine JJ. PMID: 7515579.
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PubMed Mentions:
44 Fields:
Translation:
HumansCells
-
Calu-3: a human airway epithelial cell line that shows cAMP-dependent Cl- secretion. Am J Physiol. 1994 May; 266(5 Pt 1):L493-501.
Shen BQ, Finkbeiner WE, Wine JJ, Mrsny RJ, Widdicombe JH. PMID: 7515578.
View in:
PubMed Mentions:
140 Fields:
Translation:
HumansCells
-
CFTR expression and chloride secretion in polarized immortal human bronchial epithelial cells. Am J Respir Cell Mol Biol. 1994 Jan; 10(1):38-47.
Cozens AL, Yezzi MJ, Kunzelmann K, Ohrui T, Chin L, Eng K, Finkbeiner WE, Widdicombe JH, Gruenert DC. PMID: 7507342.
View in:
PubMed Mentions:
357 Fields:
Translation:
HumansCells
-
CFTR and other Cl- channels in human airway cells. Jpn J Physiol. 1994; 44 Suppl 2:S199-205.
Wine JJ, Finkbeiner WE, Haws C, Krouse ME, Moon S, Widdicombe JH, Xia Y. PMID: 7752526.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
Altered fluid transport across airway epithelium in cystic fibrosis. Science. 1993 Oct 15; 262(5132):424-7.
Jiang C, Finkbeiner WE, Widdicombe JH, McCray PB, Miller SS. PMID: 8211164.
View in:
PubMed Mentions:
60 Fields:
Translation:
HumansCells
-
Mechanism of inhibition of cAMP-dependent epithelial chloride secretion by phorbol esters. J Biol Chem. 1993 Sep 05; 268(25):19070-5.
Shen BQ, Barthelson RA, Skach W, Gruenert DC, Sigal E, Mrsny RJ, Widdicombe JH. PMID: 7689566.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
-
Calcium-dependent chloride secretion across cultures of human tracheal surface epithelium and glands. Am J Physiol. 1993 Aug; 265(2 Pt 1):L170-7.
Yamaya M, Ohrui T, Finkbeiner WE, Widdicombe JH. PMID: 8396338.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Cultures of bovine tracheal epithelium with differentiated ultrastructure and ion transport. In Vitro Cell Dev Biol. 1993 Jan; 29A(1):19-24.
Kondo M, Finkbeiner WE, Widdicombe JH. PMID: 8444742.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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Differentiated structure and function of cultures from human tracheal epithelium. Am J Physiol. 1992 Jun; 262(6 Pt 1):L713-24.
Yamaya M, Finkbeiner WE, Chun SY, Widdicombe JH. PMID: 1616056.
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PubMed Mentions:
141 Fields:
Translation:
HumansCells
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Bovine tracheal serous cell secretion: role of cAMP and cAMP-dependent protein kinase. Am J Physiol. 1992 May; 262(5 Pt 1):L574-81.
Finkbeiner WE, Widdicombe JH, Hu L, Basbaum CB. PMID: 1375440.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Changes in permeability of dog tracheal epithelium in response to hydrostatic pressure. Am J Physiol. 1992 Feb; 262(2 Pt 1):L176-82.
Kondo M, Finkbeiner WE, Widdicombe JH. PMID: 1539675.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Calcium-dependent regulation of Cl secretion in tracheal epithelium. Am J Physiol. 1992 Feb; 262(2 Pt 1):L163-8.
Hartmann T, Kondo M, Mochizuki H, Verkman AS, Widdicombe JH. PMID: 1311517.
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PubMed Mentions:
5 Fields:
Translation:
Animals
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Arachidonic acid inhibits Cl secretion in cultures of dog tracheal epithelium. Life Sci. 1992; 50(15):1129-35.
Mochizuki H, Chao AC, Widdicombe JH. PMID: 1313520.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Ion transport by cultures of human tracheobronchial submucosal glands. Am J Physiol. 1991 Dec; 261(6 Pt 1):L485-90.
Yamaya M, Finkbeiner WE, Widdicombe JH. PMID: 1767867.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Altered ion transport by tracheal glands in cystic fibrosis. Am J Physiol. 1991 Dec; 261(6 Pt 1):L491-4.
Yamaya M, Finkbeiner WE, Widdicombe JH. PMID: 1767868.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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The basic defect in cystic fibrosis. Trends Biochem Sci. 1991 Dec; 16(12):474-7.
Widdicombe JH, Wine JJ. PMID: 1723552.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Halide transport in Xenopus oocytes. J Physiol. 1991 Nov; 443:587-99.
Katayama Y, Widdicombe JH. PMID: 1822540; PMCID: PMC1179861.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Potassium dependence of Na-Cl cotransport in dog tracheal epithelium. Am J Physiol. 1991 Oct; 261(4 Pt 1):L290-5.
Fong P, Chao AC, Widdicombe JH. PMID: 1928364.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Rapid procedure for obtaining tracheal apical membranes. Am J Physiol. 1991 Aug; 261(2 Pt 1):L102-5.
Shen BQ, Yang CM, Widdicombe JH. PMID: 1651661.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Simple technique for culture of highly differentiated cells from dog tracheal epithelium. Am J Physiol. 1991 Aug; 261(2 Pt 1):L106-17.
Kondo M, Finkbeiner WE, Widdicombe JH. PMID: 1651662.
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PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Regulation of airway mucosal ion transport. Int Arch Allergy Appl Immunol. 1991; 94(1-4):56-61.
Widdicombe JH, Kondo M, Mochizuki H. PMID: 1718899.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
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Cystic fibrosis, the CFTR, and rectifying Cl- channels. Adv Exp Med Biol. 1991; 290:253-69; discussion 269-72.
Wine JJ, Brayden DJ, Hagiwara G, Krouse ME, Law TC, Müller UJ, Solc CK, Ward CL, Widdicombe JH, Xia Y. PMID: 1719763.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
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Developmental differences in rabbit lung epithelial cell Na(+)-K(+)-ATPase. Am J Physiol. 1990 Dec; 259(6 Pt 1):L481-7.
Chapman DL, Widdicombe JH, Bland RD. PMID: 2175558.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Role of the epithelium in airway hyperreactivity. Nihon Kyobu Shikkan Gakkai Zasshi. 1990 Oct; 28(10):1272-4.
Widdicombe JH. PMID: 2273654.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Long-term culture of normal and cystic fibrosis epithelial cells grown under serum-free conditions. In Vitro Cell Dev Biol. 1990 Apr; 26(4):411-8.
Gruenert DC, Basbaum CB, Widdicombe JH. PMID: 1693142.
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PubMed Mentions:
33 Fields:
Translation:
HumansCells
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Use of cultured airway epithelial cells in studies of ion transport. Am J Physiol. 1990 Feb; 258(2 Pt 1):L13-8.
Widdicombe JH. PMID: 2407138.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Chloride conductive and cotransport mechanisms in cultures of canine tracheal epithelial cells measured by an entrapped fluorescent indicator. J Membr Biol. 1990 Feb; 113(3):193-202.
Chao AC, Widdicombe JH, Verkman AS. PMID: 2335807.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Release of cyclooxygenase products from primary cultures of tracheal epithelia of dog and human. Am J Physiol. 1989 Dec; 257(6 Pt 1):L361-5.
Widdicombe JH, Ueki IF, Emery D, Margolskee D, Yergey J, Nadel JA. PMID: 2514604.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Airway diseases: role of epithelium and inflammatory peptides. Am J Physiol. 1989 Aug; 257(2 Pt 1):L144-6.
Widdicombe JH. PMID: 2764116.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
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Quantitative fluorescence measurement of chloride transport mechanisms in phospholipid vesicles. Biochemistry. 1989 May 16; 28(10):4240-4.
Verkman AS, Takla R, Sefton B, Basbaum C, Widdicombe JH. PMID: 2765484.
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PubMed Mentions:
10 Fields:
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Chloride transport in apical membrane vesicles from bovine tracheal epithelium: characterization using a fluorescent indicator. J Membr Biol. 1988 Sep; 104(3):233-9.
Fong P, Illsley NP, Widdicombe JH, Verkman AS. PMID: 3210223.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Stimulation of Cl secretion by neurokinin A and neurokinin B in canine tracheal epithelium. Am Rev Respir Dis. 1988 Apr; 137(4):899-902.
Tamaoki J, Ueki IF, Widdicombe JH, Nadel JA. PMID: 2833141.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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A novel approach to the ultrastructural localization of cell surface receptors: affinity-gold labeling of Na, K-ATPase. Eur J Cell Biol. 1988 Feb; 45(2):200-8.
Mrsny RJ, Birrell GB, Volwerk JJ, Widdicombe JH, Griffith OH. PMID: 2835236.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Effect of human eosinophil major basic protein on ion transport in dog tracheal epithelium. Am Rev Respir Dis. 1988 Jan; 137(1):13-6.
Jacoby DB, Ueki IF, Widdicombe JH, Loegering DA, Gleich GJ, Nadel JA. PMID: 3422142.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimals
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Cyclic adenosine monophosphate-dependent kinase in cystic fibrosis tracheal epithelium. J Clin Invest. 1987 Dec; 80(6):1799-802.
Barthelson R, Widdicombe J. PMID: 3680529; PMCID: PMC442456.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Regulation of chloride secretion in dog tracheal epithelium by protein kinase C. Am J Physiol. 1987 Dec; 253(6 Pt 1):C802-8.
Barthelson RA, Jacoby DB, Widdicombe JH. PMID: 2447784.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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The pathogenesis of severe asthma: a consensus report from the Workshop on Pathogenesis. J Allergy Clin Immunol. 1987 Sep; 80(3 Pt 2):428-37.
Drazen JM, Boushey HA, Holgate ST, Kaliner M, O'Byrne P, Valentine M, Widdicombe JH, Woolcock A. PMID: 3624698.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Transport epithelial characteristics of cultured bovine pituitary follicular cells. Am J Physiol. 1987 Mar; 252(3 Pt 1):E304-12.
Ferrara N, Fujii DK, Goldsmith PC, Widdicombe JH, Weiner RI. PMID: 2881486.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Primary cultures of the dog's tracheal epithelium: fine structure, fluid, and electrolyte transport. Cell Tissue Res. 1987 Jan; 247(1):95-103.
Widdicombe JH, Coleman DL, Finkbeiner WE, Friend DS. PMID: 3829121.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Altered chloride transport of tracheal epithelium in cystic fibrosis. Prog Clin Biol Res. 1987; 254:115-26.
Widdicombe JH. PMID: 2448821.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Fluid transport by airway epithelia. Biorheology. 1987; 24(6):551-5.
Widdicombe JH. PMID: 3332079.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
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Cystic fibrosis and beta-adrenergic response of airway epithelial cell cultures. Am J Physiol. 1986 Oct; 251(4 Pt 2):R818-22.
Widdicombe JH. PMID: 3021002.
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PubMed Mentions:
30 Fields:
Translation:
Cells
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Ion transport across cat and ferret tracheal epithelia. J Appl Physiol (1985). 1986 Sep; 61(3):1065-70.
Corrales RJ, Coleman DL, Jacoby DB, Leikauf GD, Hahn HL, Nadel JA, Widdicombe JH. PMID: 3759745.
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PubMed Mentions:
4 Fields:
Translation:
Animals
-
Ion transport by tracheal epithelial cells in culture. Clin Chest Med. 1986 Jun; 7(2):299-305.
Widdicombe JH. PMID: 3522074.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Structural changes associated with fluid absorption by dog tracheal epithelium. Exp Lung Res. 1986; 10(1):57-69.
Widdicombe JH, Gashi AA, Basbaum CB, Nathanson IT. PMID: 3948811.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Alteration of chloride secretion across canine tracheal epithelium by lipoxygenase products of arachidonic acid. Am J Physiol. 1986 Jan; 250(1 Pt 2):F47-53.
Leikauf GD, Ueki IF, Widdicombe JH, Nadel JA. PMID: 3079967.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Cystic fibrosis decreases the apical membrane chloride permeability of monolayers cultured from cells of tracheal epithelium. Proc Natl Acad Sci U S A. 1985 Sep; 82(18):6167-71.
Widdicombe JH, Welsh MJ, Finkbeiner WE. PMID: 3862125; PMCID: PMC391013.
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PubMed Mentions:
60 Fields:
Translation:
HumansAnimalsCells
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Electrical properties of monolayers cultured from cells of human tracheal mucosa. J Appl Physiol (1985). 1985 May; 58(5):1729-35.
Widdicombe JH, Coleman DL, Finkbeiner WE, Tuet IK. PMID: 2581929.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Sodium-pump density of cells from dog tracheal mucosa. Am J Physiol. 1985 May; 248(5 Pt 1):C389-98.
Widdicombe JH, Basbaum CB, Highland E. PMID: 2986461.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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Bradykinin stimulates Cl secretion and prostaglandin E2 release by canine tracheal epithelium. Am J Physiol. 1985 Jan; 248(1 Pt 2):F48-55.
Leikauf GD, Ueki IF, Nadel JA, Widdicombe JH. PMID: 3918456.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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Source of the fluid component of secretions from tracheal submucosal glands in cats. J Appl Physiol Respir Environ Exerc Physiol. 1984 Apr; 56(4):1076-82.
Corrales RJ, Nadel JA, Widdicombe JH. PMID: 6725054.
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PubMed Mentions:
5 Fields:
Translation:
Animals
-
Electrical properties of dog tracheal epithelial cells grown in monolayer culture. Am J Physiol. 1984 Mar; 246(3 Pt 1):C355-9.
Coleman DL, Tuet IK, Widdicombe JH. PMID: 6367482.
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PubMed Mentions:
40 Fields:
Translation:
AnimalsCells
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Muscarinic receptors: evidence for a nonuniform distribution in tracheal smooth muscle and exocrine glands. J Neurosci. 1984 Feb; 4(2):508-20.
Basbaum CB, Grillo MA, Widdicombe JH. PMID: 6699685; PMCID: PMC6564895.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Fluid transport across airway epithelia. Ciba Found Symp. 1984; 109:109-20.
Widdicombe JH. PMID: 6569835.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Effect of vasoactive intestinal peptide on ion transport across dog tracheal epithelium. J Appl Physiol Respir Environ Exerc Physiol. 1983 Dec; 55(6):1844-8.
Nathanson I, Widdicombe JH, Barnes PJ. PMID: 6662775.
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PubMed Mentions:
8 Fields:
Translation:
Animals
-
Effects of "loop" diuretics on ion transport by dog tracheal epithelium. Am J Physiol. 1983 Nov; 245(5 Pt 1):C388-96.
Widdicombe JH, Nathanson IT, Highland E. PMID: 6638166.
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PubMed Mentions:
30 Fields:
Translation:
Animals
-
Effects of amphotericin B on ion and fluid movement across dog tracheal epithelium. J Appl Physiol Respir Environ Exerc Physiol. 1983 Oct; 55(4):1257-61.
Nathanson I, Widdicombe JH, Nadel JA. PMID: 6629959.
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PubMed Mentions:
2 Fields:
Translation:
Animals
-
Fluid and electrolyte transport across monolayers of alveolar type II cells in vitro. Am Rev Respir Dis. 1983 May; 127(5 Pt 2):S24-8.
Mason RJ, Williams MC, Widdicombe JH. PMID: 6846947.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Adrenergic and cholinergic receptors in submucosal glands of the ferret trachea: autoradiographic localization. Eur J Respir Dis Suppl. 1983; 128 (Pt 2):433-5.
Basbaum CB, Barnes PJ, Grillo MA, Widdicombe JH, Nadel JA. PMID: 6578099.
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PubMed Mentions: Fields:
Translation:
Animals
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Electrical properties of tracheal epithelium in cystic fibrosis. N Engl J Med. 1982 Dec 30; 307(27):1707-8.
Nathanson I, Widdicombe JH, Davis B. PMID: 7144871.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Transepithelial transport by pulmonary alveolar type II cells in primary culture. Proc Natl Acad Sci U S A. 1982 Oct; 79(19):6033-7.
Mason RJ, Williams MC, Widdicombe JH, Sanders MJ, Misfeldt DS, Berry LC. PMID: 6964398; PMCID: PMC347046.
View in:
PubMed Mentions:
56 Fields:
Translation:
AnimalsCells
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Ion contents and other properties of isolated cells from dog tracheal epithelium. Am J Physiol. 1981 Nov; 241(5):C184-92.
Widdicombe JH, Basbaum CB, Highland E. PMID: 7304731.
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PubMed Mentions:
20 Fields:
Translation:
Animals
-
Ion transport by dog tracheal epithelium. Fed Proc. 1980 Nov; 39(13):3062-6.
Widdicombe JH, Welsh MJ. PMID: 6253330.
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PubMed Mentions:
28 Fields:
Translation:
Animals
-
Fluid transport across the canine tracheal epithelium. J Appl Physiol Respir Environ Exerc Physiol. 1980 Nov; 49(5):905-9.
Welsh MJ, Widdicombe JH, Nadel JA. PMID: 7429914.
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PubMed Mentions:
17 Fields:
Translation:
Animals
-
Pathways of ion movement in the canine tracheal epithelium. Am J Physiol. 1980 Sep; 239(3):F215-21.
Welsh MJ, Widdicombe JH. PMID: 7435560.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Anion selectivity of the chloride-transport process in dog tracheal epithelium. Am J Physiol. 1980 Sep; 239(3):C112-7.
Widdicombe JH, Welsh MJ. PMID: 7435549.
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PubMed Mentions:
6 Fields:
Translation:
Animals
-
A possible role of linked Na and Cl movement in active Cl uptake in smooth muscle. Pflugers Arch. 1980 Jul; 386(1):35-7.
Widdicombe JH, Brading AF. PMID: 7191961.
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PubMed Mentions:
5 Fields:
Translation:
Animals
-
The uptake and efflux of alpha-aminoisobutyric acid by the smooth muscle of the guinea pig's taenia coli. Can J Physiol Pharmacol. 1979 Oct; 57(10):1114-21.
Widdicombe JH, Paton DM. PMID: 509365.
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PubMed Mentions:
1 Fields:
Translation:
Animals
-
Localization of Na pumps in the tracheal epithelium of the dog. J Cell Biol. 1979 Aug; 82(2):380-90.
Widdicombe JH, Basbaum CB, Yee JY. PMID: 225337; PMCID: PMC2110467.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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The effects of sodium substitution and ouabain on ion transport by dog tracheal epithelium. Am Rev Respir Dis. 1979 Aug; 120(2):385-92.
Widdicombe JH, Ueki IF, Bruderman I, Nadel JA. PMID: 475157.
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PubMed Mentions:
18 Fields:
Translation:
Animals
-
Fine structure and innervation of smooth muscle in the monkey oviduct. Gynecol Obstet Invest. 1979; 10(5):221-30.
Widdicombe JH, Paton DM. PMID: 119676.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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The role of the adrenergic innervation of the oviduct in the regulation of mammalian ovum transport. Pharmacol Rev. 1977 Jun; 29(2):67-102.
Paton DM, Widdicombe JH, Rheaume DE, Johns A. PMID: 353829.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
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Responses of the monkey oviduct to transmural electrical stimulation and to drugs. J Reprod Fertil. 1977 May; 50(1):141-4.
Widdicombe JH, Johns A, Paton DM. PMID: 405490.
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PubMed Mentions: Fields:
Translation:
Animals
-
Ouabain-sensitive ion fluxes in the smooth muscle of the guinea-pig's taenia coli. J Physiol. 1977 Apr; 266(2):235-54.
Widdicombe JH. PMID: 857001; PMCID: PMC1283564.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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The use of lanthanum to estimate the numbers of extracellular cation-exchanging sites in the guinea-pig's taenia coli, and its effects on transmembrane monovalent ion movements. J Physiol. 1977 Apr; 266(2):255-73.
Brading AF, Widdicombe JH. PMID: 857002; PMCID: PMC1283565.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Proceedings: The effect of lanthanum on ion content and movement in the guinea-pig's taenia coli. J Physiol. 1974 Sep; 241(2):106P-107P.
Widdicombe JH. PMID: 4443902.
View in:
PubMed Mentions:
5 Fields:
Translation:
Animals
-
An estimate of sodium-potassium pump activity and the number of pump sites in the smooth muscle of the guinea-pig taenia coli, using (3H)ouabain. J Physiol. 1974 Apr; 238(2):235-49.
Brading AF, Widdicombe JH. PMID: 4840873; PMCID: PMC1330877.
View in:
PubMed Mentions:
20 Fields:
Translation:
AnimalsCells