Neal Fleming

Title(s)Professor Emeritus, MED: Anesth & Pain Medicine
SchoolSchool of Medicine
AddressPSSB/UCDMC
CA 95817
Phone916-734-5046
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Comparison of Differences in Cohort (Forward) and Case Control (Backward) Methodologic Approaches for Validation of the Hypotension Prediction Index. Anesthesiology. 2024 Sep 01; 141(3):443-452. Davies SJ, Sessler DI, Jian Z, Fleming NW, Mythen M, Maheshwari K, Veelo DP, Vlaar APJ, Settels J, Scheeren T, van der Ster BJP, Sander M, Cannesson M, Hatib F. PMID: 38557791; PMCID: PMC11323758.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    2. Performance of pulse oximeters as a function of race compared to skin pigmentation: a single center retrospective study. J Clin Monit Comput. 2024 Aug 28. Marlar AI, Knabe BK, Taghikhan Y, Applegate RL, Fleming NW. PMID: 39196478.
      View in: PubMed   Mentions: 1     Fields:    
    3. A retrospective study of the effects of a vasopressor bolus on systolic slope (dP/dt) and dynamic arterial elastance (Eadyn). BMC Anesthesiol. 2024 Jul 29; 24(1):257. Abdallah AC, Song SH, Fleming NW. PMID: 39075354; PMCID: PMC11285466.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Publications Among Pain Medicine Fellowship-Trained American Board of Anesthesiology Diplomates. Cureus. 2024 Jun; 16(6):e61821. Jones JH, Fleming N. PMID: 38975435; PMCID: PMC11227611.
      View in: PubMed   Mentions:
    5. Quality Improvement Projects and Anesthesiology Graduate Medical Education: A Systematic Review. Cureus. 2024 Apr; 16(4):e57908. Jones JH, Fleming N. PMID: 38725749; PMCID: PMC11079850.
      View in: PubMed   Mentions:
    6. The effects of an IV fluid bolus on mitral annular velocity and the assessment of diastolic function: a prospective non-randomized study. BMC Anesthesiol. 2024 03 26; 24(1):117. Ayala S, Badakhsh O, Li D, Fleming NW. PMID: 38532344; PMCID: PMC10964498.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. The problem with dichotomizing quality improvement measures. BMC Anesthesiol. 2022 09 19; 22(1):297. Jones JH, Fleming N. PMID: 36123624; PMCID: PMC9484068.
      View in: PubMed   Mentions: 1     Fields:    
    8. Assisted Fluid Management Software Guidance for Intraoperative Fluid Administration. Anesthesiology. 2021 08 01; 135(2):273-283. Maheshwari K, Malhotra G, Bao X, Lahsaei P, Hand WR, Fleming NW, Ramsingh D, Treggiari MM, Sessler DI, Miller TE, Assisted Fluid Management Study Team. PMID: 33901281.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    9. Simultaneous comparison of depth of sedation performance between SedLine and BIS during general anesthesia using custom passive interface hardware: study protocol for a prospective, non-blinded, non-randomized trial. BMC Anesthesiol. 2021 04 06; 21(1):105. Jones JH, Nittur VR, Fleming N, Applegate RL. PMID: 33823811; PMCID: PMC8022390.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    10. Oxygen Reserve Index: Utility as an Early Warning for Desaturation in High-Risk Surgical Patients. Anesth Analg. 2021 03 01; 132(3):770-776. Fleming NW, Singh A, Lee L, Applegate RL. PMID: 32815872.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    11. Use of the Hypotension Prediction Index During Cardiac Surgery. J Cardiothorac Vasc Anesth. 2021 Jun; 35(6):1769-1775. Shin B, Maler SA, Reddy K, Fleming NW. PMID: 33446404.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    12. Percutaneous cannulation for extracorporeal membrane oxygenation (ECMO): A method for pig experimental models. MethodsX. 2020; 7:100979. Fritz C, Viault N, Fohlen B, Edlinger-Stanger M, McGregor H, Cholley B, Fleming N. PMID: 32670807; PMCID: PMC7338622.
      View in: PubMed   Mentions: 1  
    13. Study of early warning for desaturation provided by Oxygen Reserve Index in obese patients. J Clin Monit Comput. 2021 08; 35(4):749-756. Tsymbal E, Ayala S, Singh A, Applegate RL, Fleming NW. PMID: 32424516; PMCID: PMC8286939.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    14. In Response: Sedation After Cardiac Surgery With Propofol or Dexmedetomidine: Between Scylla and Charybdis? Anesth Analg. 2017 11; 125(5):1822-1823. Liu H, Ji F, Peng K, Applegate RL, Fleming NW. PMID: 28914652.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    15. Sedation After Cardiac Surgery: Is One Drug Better Than Another? Anesth Analg. 2017 04; 124(4):1061-1070. Liu H, Ji F, Peng K, Applegate RL, Fleming N. PMID: 27984229.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    16. The Utility of 3D Left Atrial Volume and Mitral Flow Velocities as Guides for Acute Volume Resuscitation. Biomed Res Int. 2015; 2015:697327. Santosa CM, Rose DD, Fleming NW. PMID: 26236733; PMCID: PMC4508382.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    17. Current use of the pulmonary artery catheter in cardiac surgery: a survey study. J Cardiothorac Vasc Anesth. 2015 Feb; 29(1):69-75. Judge O, Ji F, Fleming N, Liu H. PMID: 25440650.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    18. Reliability of a new 4th generation FloTrac algorithm to track cardiac output changes in patients receiving phenylephrine. J Clin Monit Comput. 2015 Aug; 29(4):467-73. Ji F, Li J, Fleming N, Rose D, Liu H. PMID: 25267438; PMCID: PMC4379136.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    19. Response to letters regarding article, "perioperative dexmedetomidine improves outcomes of cardiac surgery". Circulation. 2013 Oct 15; 128(16):e339-40. Ji F, Li Z, Nguyen H, Young N, Shi P, Fleming N, Liu H. PMID: 24126331.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    20. Perioperative dexmedetomidine improves outcomes of cardiac surgery. Circulation. 2013 Apr 16; 127(15):1576-84. Ji F, Li Z, Nguyen H, Young N, Shi P, Fleming N, Liu H. PMID: 23513068; PMCID: PMC3979354.
      View in: PubMed   Mentions: 101     Fields:    Translation:HumansCTClinical Trials
    21. Age-associated differences in gene expression in response to delayed anesthetic preconditioning. Age (Dordr). 2012 Dec; 34(6):1459-72. Zhong C, Fleming N, Lu X, Moore P, Liu H. PMID: 22009153; PMCID: PMC3528372.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    22. Stroke volume variation during acute normovolemic hemodilution. Anesth Analg. 2009 Dec; 109(6):1823-30. Kungys G, Rose DD, Fleming NW. PMID: 19923509.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCTClinical Trials
    23. Fluid therapy monitors in acute infarction. Acta Anaesthesiol Scand. 2009 Jul; 53(6):836; author reply 836-7. Fleming NW. PMID: 19563577.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. Right heart embolism and acute right atrial dilation during total knee arthroplasty. Anesth Analg. 2007 Nov; 105(5):1224-7. Singh A, Fleming N. PMID: 17959945.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. Anesthetic preconditioning combined with postconditioning offers no additional benefit over preconditioning or postconditioning alone. Anesth Analg. 2007 Aug; 105(2):316-24. Deyhimy DI, Fleming NW, Brodkin IG, Liu H. PMID: 17646483.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    26. Septal interstitial cells of Cajal conduct pacemaker activity to excite muscle bundles in human jejunum. Gastroenterology. 2007 Sep; 133(3):907-17. Lee HT, Hennig GW, Fleming NW, Keef KD, Spencer NJ, Ward SM, Sanders KM, Smith TK. PMID: 17678922; PMCID: PMC2077833.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    27. The mechanism and spread of pacemaker activity through myenteric interstitial cells of Cajal in human small intestine. Gastroenterology. 2007 May; 132(5):1852-65. Lee HT, Hennig GW, Fleming NW, Keef KD, Spencer NJ, Ward SM, Sanders KM, Smith TK. PMID: 17484879.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    28. Contact activation via ICAM-1 induces changes in airway epithelial permeability in vitro. Immunol Invest. 2007; 36(1):59-72. Choi H, Fleming NW, Serikov VB. PMID: 17190650.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    29. Template switching within exons 3 and 4 of KV11.1 (HERG) gives rise to a 5' truncated cDNA. Biochem Biophys Res Commun. 2006 Jul 14; 345(4):1342-9. Ro S, Kang SH, Farrelly AM, Ordog T, Partain R, Fleming N, Sanders KM, Kenyon JL, Keef KD. PMID: 16723117.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    30. Lung heat transfer. Eur J Appl Physiol. 2004 Aug; 92(4-5):606; author reply 607-8. Schlimp CJ, Wiedermann FJ. PMID: 15170572.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    31. Cardiac output monitoring during off-pump coronary artery bypass grafting. J Cardiothorac Vasc Anesth. 2004 Feb; 18(1):43-6. Grow MP, Singh A, Fleming NW, Young N, Watnik M. PMID: 14973798.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    32. Endotoxin induces leukocyte transmigration and changes in permeability of the airway epithelium via protein-kinase C and extracellular regulated kinase activation. J Endotoxin Res. 2004; 10(1):55-65. Serikov VB, Choi H, Schmiel K, Skaggs C, Fleming NW, Wu R, Widdicombe JH. PMID: 15025824.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    33. Effects of pneumoperitoneum on intraoperative pulmonary mechanics and gas exchange during laparoscopic gastric bypass. Surg Endosc. 2004 Jan; 18(1):64-71. Nguyen NT, Anderson JT, Budd M, Fleming NW, Ho HS, Jahr J, Stevens CM, Wolfe BM. PMID: 14625752.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCTClinical Trials
    34. Effects of the ventilation pattern and pulmonary blood flow on lung heat transfer. Eur J Appl Physiol. 2004 Mar; 91(2-3):314-23. Serikov VB, Fleming NW, Talalov VA, Stawitcke FA. PMID: 14586583.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    35. Tyloxapol attenuates the pathologic effects of endotoxin in rabbits and mortality following cecal ligation and puncture in rats by blockade of endotoxin receptor-ligand interactions. Inflammation. 2003 Aug; 27(4):175-90. Serikov VB, Glazanova TV, Jerome EH, Fleming NW, Higashimori H, Staub NC. PMID: 14527171.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    36. Comparison of postoperative hepatic function after laparoscopic versus open gastric bypass. Am J Surg. 2003 Jul; 186(1):40-4. Nguyen NT, Braley S, Fleming NW, Lambourne L, Rivers R, Wolfe BM. PMID: 12842747.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCTClinical Trials
    37. Expression and function of KCNH2 (HERG) in the human jejunum. Am J Physiol Gastrointest Liver Physiol. 2003 Jun; 284(6):G883-95. Farrelly AM, Ro S, Callaghan BP, Khoyi MA, Fleming N, Horowitz B, Sanders KM, Keef KD. PMID: 12736144.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    38. Unexpected pressure waveform during pulmonary artery catheter placement. J Cardiothorac Vasc Anesth. 2003 Feb; 17(1):129-30. Grow MP, Fleming N, Liu H. PMID: 12635075.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    39. Effect of prolonged pneumoperitoneum on intraoperative urine output during laparoscopic gastric bypass. J Am Coll Surg. 2002 Oct; 195(4):476-83. Nguyen NT, Perez RV, Fleming N, Rivers R, Wolfe BM. PMID: 12375752.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCTClinical Trials
    40. Anticoagulation for patients with heparin-induced thrombocytopenia using recombinant hirudin during cardiopulmonary bypass. J Clin Anesth. 2002 Sep; 14(6):452-5. Liu H, Fleming NW, Moore PG. PMID: 12393116.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    41. Effect of heated and humidified carbon dioxide gas on core temperature and postoperative pain: a randomized trial. Surg Endosc. 2002 Jul; 16(7):1050-4. Nguyen NT, Furdui G, Fleming NW, Lee SJ, Goldman CD, Singh A, Wolfe BM. PMID: 12165821.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCTClinical Trials
    42. Pulmonary and bronchial circulations: contributions to heat and water exchange in isolated lungs. J Appl Physiol (1985). 2001 Nov; 91(5):1977-85. Serikov VB, Fleming NW. PMID: 11641333.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    43. Cardiac function during laparoscopic vs open gastric bypass. Surg Endosc. 2002 Jan; 16(1):78-83. Nguyen NT, Ho HS, Fleming NW, Moore P, Lee SJ, Goldman CD, Cole CJ, Wolfe BM. PMID: 11961610.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCTClinical Trials
    44. Evaluation of core temperature during laparoscopic and open gastric bypass. Obes Surg. 2001 Oct; 11(5):570-5. Nguyen NT, Fleming NW, Singh A, Lee SJ, Goldman CD, Wolfe BM. PMID: 11594097.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCTClinical Trials
    45. Comparison of pulmonary function and postoperative pain after laparoscopic versus open gastric bypass: a randomized trial. J Am Coll Surg. 2001 Apr; 192(4):469-76; discussion 476-7. Nguyen NT, Lee SL, Goldman C, Fleming N, Arango A, McFall R, Wolfe BM. PMID: 11294404.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCTClinical Trials
    46. Comparison of the intubation conditions provided by rapacuronium (ORG 9487) or succinylcholine in humans during anesthesia with fentanyl and propofol. Anesthesiology. 1999 Nov; 91(5):1311-7. Fleming NW, Chung F, Glass PS, Kitts JB, Kirkegaard-Nielsen H, Gronert GA, Chan V, Gan TJ, Cicutti N, Caldwell JE. PMID: 10551582.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    47. Control of motility patterns in the human colonic circular muscle layer by pacemaker activity. J Physiol. 1998 Jul 01; 510 ( Pt 1):309-20. Rae MG, Fleming N, McGregor DB, Sanders KM, Keef KD. PMID: 9625887; PMCID: PMC2231034.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    48. Airway thermal volume in humans and its relation to body size. J Appl Physiol (1985). 1997 Aug; 83(2):668-76. Serikov VB, Jerome EH, Fleming NW, Moore PG, Stawitcke FA, Staub NC. PMID: 9262466.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    49. Anticholinesterases and subsequent duration of block of suxamethonium. Br J Anaesth. 1997 Apr; 78(4):480-1. Graham SG. PMID: 9135338.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    50. Neuromuscular blocking action of suxamethonium after antagonism of vecuronium by edrophonium, pyridostigmine or neostigmine. Br J Anaesth. 1996 Oct; 77(4):492-5. Fleming NW, Macres S, Antognini JF, Vengco J. PMID: 8942334.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsCTClinical Trials
    51. Con: The choice of muscle relaxants is not important in cardiac surgery. J Cardiothorac Vasc Anesth. 1995 Dec; 9(6):772-4. Fleming N. PMID: 8664475.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    52. Aberrant responses to muscle relaxants produced by diseases or drugs. Journal of Critical Care. 1995 Dec 1; 14(4):283-290. Gronert GG, Fleming FN, Antognini AJ. .
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    53. Cholinesterase inhibitors do not prolong neuromuscular block produced by mivacurium. Br J Anaesth. 1994 Aug; 73(2):241-3. Fleming NW, Lewis BK. PMID: 7917744.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    54. Effects of cholinesterase inhibitors on the neuromuscular blocking action of suxamethonium. Br J Anaesth. 1994 Feb; 72(2):237-9. Valdrighi JB, Fleming NW, Smith BK, Baker GL, White DA. PMID: 8110583.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    55. Triggering the IABP. J Cardiothorac Vasc Anesth. 1993 Aug; 7(4):504-5. Newswanger D, Fleming N. PMID: 8400110.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    56. Acute effects of calcitonin gene-related peptide on the mechanical and electrical responses of the rat hemidiaphragm. J Pharmacol Exp Ther. 1993 Jun; 265(3):1199-204. Fleming NW, Lewis BK, White DA, Dretchen KL. PMID: 8510003.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    57. Opioid-induced spasm of the sphincter of Oddi apparently reversed by nalbuphine. Anesth Analg. 1992 Feb; 74(2):308-10. Humphreys HK, Fleming NW. PMID: 1731556.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    58. Lack of interaction between prior succinylcholine administration and doxacurium-induced neuromuscular block. Anesth Analg. 1991 Aug; 73(2):237-8. Abou-Donia MM. PMID: 1830195.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    59. Mechanisms of respiratory failure produced by neostigmine and diisopropyl fluorophosphate. Eur J Pharmacol. 1991 Mar 19; 195(1):85-91. Fleming NW, Henderson TR, Dretchen KL. PMID: 2065714.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    60. Effects of succinylcholine on the pharmacodynamics of pipecuronium and pancuronium. Anesth Analg. 1991 Mar; 72(3):364-8. Dubois MY, Fleming NW, Lea DE. PMID: 1847278.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    61. Pulmonary edema after PGE1 infusion. J Cardiothorac Anesth. 1990 Dec; 4(6):744-7. White JL, Fleming NW, Burke TA, Katz NM, Moront MG, Kim YD. PMID: 2131906.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    62. Infusion rate and hemodynamics with desmopressin. J Cardiothorac Anesth. 1989 Dec; 3(6):813-5. Fleming NW, Burke TA. PMID: 2521042.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    63. Intubation with low-dose atracurium in children. Anesth Analg. 1989 May; 68(5):609-13. Ved SA, Chen J, Reed M, Fleming N. PMID: 2719291.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    64. Treatment of non-cardiogenic pulmonary edema following cardiopulmonary bypass with veno-venous extracorporeal membrane oxygenation. Anesthesiology. 1988 Oct; 69(4):609-14. Pilato MA, Fleming NW, Katz NM, O'Connell JJ, Krucoff MW, Siegelman RE, Kim YD. PMID: 3052177.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    65. Potential eye damage from reusable masks. Anesthesiology. 1987 Sep; 67(3):444. Durkan W, Fleming N. PMID: 3631620.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    66. Medullary effects of local anesthetics. Anesth Analg. 1987 Apr; 66(4):371-3. Fleming N. PMID: 3565808.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    67. Dental rolls for eye operations. Anesthesiology. 1987 Mar; 66(3):437. Kataria B, Fleming N. PMID: 3826710.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    68. Chromatographic and kinetic properties of acid- and pepsin-activated inactive renin from human amniotic fluid. Biochem Pharmacol. 1979 Sep 01; 28(17):2597-600. Johnson RL, Fleming NW, Poisner AM. PMID: 42402.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
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