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Kuang-Yu Jen

Title(s)Associate Professor, Pathology and Laboratory Medicine
SchoolUniversity of California, Davis
Address4400 V Street
CA 95817
Phone916-734-2579
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Improving the accuracy of gastrointestinal neuroendocrine tumor grading with deep learning. Sci Rep. 2020 Jul 06; 10(1):11064. Govind D, Jen KY, Matsukuma K, Gao G, Olson KA, Gui D, Wilding GE, Border SP, Sarder P. PMID: 32632119.
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    2. Clinicopathologic Characteristics of JC Virus Nephropathy in Kidney Transplant Recipients. Transplantation. 2020 Jun 17. Wiegley N, Walavalkar V, Aujla H, Chen LX, Huang Y, Lee BK, Jen KY. PMID: 32639410.
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    3. Tonsillar Kaposi Sarcoma in a Renal Transplant Patient. Transpl Infect Dis. 2020 Jun 04; e13347. Howard JH, Darrow M, Chen LX, Alnimri M, Jen KY. PMID: 32495980.
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    4. Generative modeling for label-free glomerular modeling and classification. Proc SPIE Int Soc Opt Eng. 2020 Feb; 11320. Lutnick B, Ginley B, Jen KY, Dong W, Sarder P. PMID: 32362708.
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    5. Probabilistic modeling of Diabetic Nephropathy progression. Proc SPIE Int Soc Opt Eng. 2020 Feb; 11320. Border S, Jen KY, Dos-Santos WL, Tomaszewski J, Sarder P. PMID: 32382209.
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    6. Sonographically Diagnosed Urothelial Thickening in Kidney Allografts: A Noninvasive and Clinically Highly Relevant Marker for the Detection of Acute Rejection. AJR Am J Roentgenol. 2020 Jul; 215(1):148-152. Fananapazir G, Navarro SM, Zhou C, Jen KY, Loehfelm TW, Stewart SL, Troppmann C, Lamba R. PMID: 32097029.
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    7. Membranoproliferative Glomerulonephritis Associated with Nivolumab Therapy. Case Rep Nephrol. 2020; 2020:2638283. Cruz-Whitley J, Giehl N, Jen KY, Young B. PMID: 32257470.
      View in: PubMed   Mentions:
    8. Digital Whole Slide Imaging Compared With Light Microscopy for Primary Diagnosis in Surgical Pathology: A Multicenter, Double-Blinded, Randomized Study of 2045 Cases. Arch Pathol Lab Med. 2020 Feb 14. Borowsky AD, Glassy EF, Wallace WD, Kallichanda NS, Behling CA, Miller DV, Oswal HN, Feddersen RM, Bakhtar OR, Mendoza AE, Molden DP, Saffer HL, Wixom CR, Albro JE, Cessna MH, Hall BJ, Lloyd IE, Bishop JW, Darrow MA, Gui D, Jen KY, Walby JAS, Bauer SM, Cortez DA, Gandhi P, Rodgers MM, Rodriguez RA, Martin DR, McConnell TG, Reynolds SJ, Spigel JH, Stepenaskie SA, Viktorova E, Magari R, Wharton KA, Qiu J, Bauer TW. PMID: 32057275.
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    9. Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice. Nat Commun. 2020 01 20; 11(1):394. Rose Li Y, Halliwill KD, Adams CJ, Iyer V, Riva L, Mamunur R, Jen KY, Del Rosario R, Fredlund E, Hirst G, Alexandrov LB, Adams D, Balmain A. PMID: 31959748.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsPHPublic Health
    10. Dual-mode emission and transmission microscopy for virtual histochemistry using hematoxylin- and eosin-stained tissue sections. Biomed Opt Express. 2019 Dec 01; 10(12):6516-6530. Fereidouni F, Todd A, Li Y, Chang CW, Luong K, Rosenberg A, Lee YJ, Chan JW, Borowsky A, Matsukuma K, Jen KY, Levenson R. PMID: 31853414.
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    11. Computational Segmentation and Classification of Diabetic Glomerulosclerosis. J Am Soc Nephrol. 2019 10; 30(10):1953-1967. Ginley B, Lutnick B, Jen KY, Fogo AB, Jain S, Rosenberg A, Walavalkar V, Wilding G, Tomaszewski JE, Yacoub R, Rossi GM, Sarder P. PMID: 31488606.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Donor Characteristics, Recipient Outcomes, and Histologic Findings of Kidney Allografts With Diffuse Donor-derived Glomerular Fibrin Thrombi. Transplantation. 2019 09; 103(9):1921-1927. Gao G, Chen LX, Brown IE, De Mattos A, Perez RV, Jen KY. PMID: 30720684.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Examining Structural Patterns and Causality in Diabetic Nephropathy using inter-Glomerular Distance and Bayesian Graphical Models. Proc SPIE Int Soc Opt Eng. 2019 Feb; 10956. Majumdar A, Jen KY, Jain S, Tomaszewski JE, Sarder P. PMID: 31186597.
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    14. Diverse tumour susceptibility in Collaborative Cross mice: identification of a new mouse model for human gastric tumourigenesis. Gut. 2019 11; 68(11):1942-1952. Wang P, Wang Y, Langley SA, Zhou YX, Jen KY, Sun Q, Brislawn C, Rojas CM, Wahl KL, Wang T, Fan X, Jansson JK, Celniker SE, Zou X, Threadgill DW, Snijders AM, Mao JH. PMID: 30842212.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    15. An integrated iterative annotation technique for easing neural network training in medical image analysis. Nat Mach Intell. 2019 Feb; 1(2):112-119. Lutnick B, Ginley B, Govind D, McGarry SD, LaViolette PS, Yacoub R, Jain S, Tomaszewski JE, Jen KY, Sarder P. PMID: 31187088.
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    16. Combined Ex Vivo Hypothermic and Normothermic Perfusion for Assessment of High-risk Deceased Donor Human Kidneys for Transplantation. Transplantation. 2019 02; 103(2):392-400. Kabagambe SK, Palma IP, Smolin Y, Boyer T, Palma I, Sageshima J, Troppmann C, Santhanakrishnan C, McVicar JP, Jen KY, Nuño M, Perez RV. PMID: 29952816.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. No difference in 4-nitroquinoline induced tumorigenesis between germ-free and colonized mice. Mol Carcinog. 2019 05; 58(5):627-632. Zhou YX, Fuentes-Creollo G, Ponce F, Langley SA, Jen KY, Celniker SE, Mao JH, Snijders AM. PMID: 30632250.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    18. Histopathologic Findings on Implantation Renal Allograft Biopsies Correlate With Kidney Donor Profile Index and 30-Day Serum Creatinine. Transplant Proc. 2019 Apr; 51(3):639-646. Chen LX, Francalacci LC, Bang H, De Mattos A, Perez RV, Jen KY. PMID: 30979446.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    19. Lupus Nephritis. . 2019 Jan 1; 153-168. Kartik Pillutla, Kuang-Yu Jen. .
      View in: Publisher Site   Mentions:
    20. Focal and Segmental Glomerulosclerosis (FSGS). . 2019 Jan 1; 129-151. Stephanie Nguyen, Kuang-Yu Jen. .
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    21. Arginine reprogramming in ADPKD results in arginine-dependent cystogenesis. Am J Physiol Renal Physiol. 2018 12 01; 315(6):F1855-F1868. Trott JF, Hwang VJ, Ishimaru T, Chmiel KJ, Zhou JX, Shim K, Stewart BJ, Mahjoub MR, Jen KY, Barupal DK, Li X, Weiss RH. PMID: 30280600.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    22. Identification of high-risk human papillomavirus and Rb/E2F pathway genomic alterations in mutually exclusive subsets of colorectal neuroendocrine carcinoma. Mod Pathol. 2019 02; 32(2):290-305. Shamir ER, Devine WP, Pekmezci M, Umetsu SE, Krings G, Federman S, Cho SJ, Saunders TA, Jen KY, Bergsland E, Jones K, Kim GE, Kakar S, Chiu CY, Joseph NM. PMID: 30237525.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    23. Severe Renal Allograft Rejection Resulting from Lenalidomide Therapy for Multiple Myeloma: Case Report. Transplant Proc. 2018 Apr; 50(3):873-876. Walavalkar V, Adey DB, Laszik ZG, Jen KY. PMID: 29661456.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. Deep variational auto-encoders for unsupervised glomerular classification. . 2018 Mar 6; 10581:105810c. Brendon Lutnick, Rabi Yacoub, Kuang-Yu Jen, John E. Tomaszewski, Sanjay Jain, Pinaki Sarder. .
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    25. Computational analysis of the structural progression of human glomeruli in diabetic nephropathy. . 2018 Mar 6; 10581:105810a. Brandon G. Ginley, John E. Tomaszewski, Kuang-Yu Jen, Agnes Fogo, Sanjay Jain, Pinaki Sarder. .
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    26. Short-term early exposure to thirdhand cigarette smoke increases lung cancer incidence in mice. Clin Sci (Lond). 2018 02 28; 132(4):475-488. Hang B, Wang Y, Huang Y, Wang P, Langley SA, Bi L, Sarker AH, Schick SF, Havel C, Jacob P, Benowitz N, Destaillats H, Tang X, Xia Y, Jen KY, Gundel LA, Mao JH, Snijders AM. PMID: 29440622.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsPHPublic Health
    27. Cocaine/levamisole-associated autoimmune syndrome: a disease of neutrophil-mediated autoimmunity. Curr Opin Hematol. 2018 Jan; 25(1):29-36. Cascio MJ, Jen KY. PMID: 29211697.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    28. Hepatic steatosis after pediatric liver transplant. Liver Transpl. 2017 07; 23(7):957-967. Perito ER, Vase T, Ramachandran R, Phelps A, Jen KY, Lustig RH, Feldstein VA, Rosenthal P. PMID: 28426902.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    29. MET Exon 14 Mutation Encodes an Actionable Therapeutic Target in Lung Adenocarcinoma. Cancer Res. 2017 08 15; 77(16):4498-4505. Lu X, Peled N, Greer J, Wu W, Choi P, Berger AH, Wong S, Jen KY, Seo Y, Hann B, Brooks A, Meyerson M, Collisson EA. PMID: 28522754.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    30. Donor Liver Small Droplet Macrovesicular Steatosis Is Associated With Increased Risk for Recipient Allograft Rejection. Am J Surg Pathol. 2017 Mar; 41(3):365-373. Choi WT, Jen KY, Wang D, Tavakol M, Roberts JP, Gill RM. PMID: 28059835.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    31. Nucks1 synergizes with Trp53 to promote radiation lymphomagenesis in mice. Oncotarget. 2016 Sep 20; 7(38):61874-61889. Yue Y, Leung SG, Liu Y, Huang Y, Grundt K, Østvold AC, Jen KY, Schild D, Mao JH, Wiese C. PMID: 27542204.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    32. Characteristics of AA amyloidosis patients in San Francisco. Nephrology (Carlton). 2016 Apr; 21(4):308-13. Lejmi H, Jen KY, Olson JL, James SH, Sam R. PMID: 26370715.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    33. Whole exome and targeted deep sequencing identify genome-wide allelic loss and frequent SETDB1 mutations in malignant pleural mesotheliomas. Oncotarget. 2016 Feb 16; 7(7):8321-31. Kang HC, Kim HK, Lee S, Mendez P, Kim JW, Woodard G, Yoon JH, Jen KY, Fang LT, Jones K, Jablons DM, Kim IJ. PMID: 26824986.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    34. Evolution of metastasis revealed by mutational landscapes of chemically induced skin cancers. Nat Med. 2015 Dec; 21(12):1514-20. McCreery MQ, Halliwill KD, Chin D, Delrosario R, Hirst G, Vuong P, Jen KY, Hewinson J, Adams DJ, Balmain A. PMID: 26523969.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    35. The Trp53 delta proline (Trp53?P) mouse exhibits increased genome instability and susceptibility to radiation-induced, but not spontaneous, tumor development. Mol Carcinog. 2016 09; 55(9):1387-96. Adams CJ, Yu JS, Mao JH, Jen KY, Costes SV, Wade M, Shoemake J, Aina OH, Del Rosario R, Menchavez PT, Cardiff RD, Wahl GM, Balmain A. PMID: 26310697.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    36. Pathologic manifestations of levamisole-adulterated cocaine exposure. Diagn Pathol. 2015 May 06; 10:48. Nolan AL, Jen KY. PMID: 25943359.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansPHPublic Health
    37. The mutational landscapes of genetic and chemical models of Kras-driven lung cancer. Nature. 2015 Jan 22; 517(7535):489-92. Westcott PM, Halliwill KD, To MD, Rashid M, Rust AG, Keane TM, Delrosario R, Jen KY, Gurley KE, Kemp CJ, Fredlund E, Quigley DA, Adams DJ, Balmain A. PMID: 25363767.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansAnimals
    38. Pauci-immune glomerulonephritis in individuals with disease associated with levamisole-adulterated cocaine: a series of 4 cases. Medicine (Baltimore). 2014 Oct; 93(17):290-7. Carlson AQ, Tuot DS, Jen KY, Butcher B, Graf J, Sam R, Imboden JB. PMID: 25398064.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansPHPublic Health
    39. Monoclonal light chain deposits within the stomach manifesting as immunotactoid gastropathy. Ultrastruct Pathol. 2015 Feb; 39(1):62-8. Jen KY, Fix OK, Foster EN, Laszik ZG, Ferrell LD. PMID: 25191812.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    40. Noninvasive in vivo imaging of diabetes-induced renal oxidative stress and response to therapy using hyperpolarized 13C dehydroascorbate magnetic resonance. Diabetes. 2015 Feb; 64(2):344-52. Keshari KR, Wilson DM, Sai V, Bok R, Jen KY, Larson P, Van Criekinge M, Kurhanewicz J, Wang ZJ. PMID: 25187363.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    41. Lupus-like membranous nephropathy: Is it lupus or not? Clin Exp Nephrol. 2015 Jun; 19(3):395-402. Sam R, Joshi A, James S, Jen KY, Amani F, Hart P, Schwartz MM. PMID: 24993947.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    42. CUL4A induces epithelial-mesenchymal transition and promotes cancer metastasis by regulating ZEB1 expression. Cancer Res. 2014 Jan 15; 74(2):520-31. Wang Y, Wen M, Kwon Y, Xu Y, Liu Y, Zhang P, He X, Wang Q, Huang Y, Jen KY, LaBarge MA, You L, Kogan SC, Gray JW, Mao JH, Wei G. PMID: 24305877.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    43. Inflammation and Hras signaling control epithelial-mesenchymal transition during skin tumor progression. Genes Dev. 2013 Mar 15; 27(6):670-82. Wong CE, Yu JS, Quigley DA, To MD, Jen KY, Huang PY, Del Rosario R, Balmain A. PMID: 23512660.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    44. Recurrent HIV-associated immune complex glomerulonephritis with lupus-like features after kidney transplantation. Am J Kidney Dis. 2013 Aug; 62(2):335-8. Chandran S, Jen KY, Laszik ZG. PMID: 23481367.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    45. Rewiring of human lung cell lineage and mitotic networks in lung adenocarcinomas. Nat Commun. 2013; 4:1701. Kim IJ, Quigley D, To MD, Pham P, Lin K, Jo B, Jen KY, Raz D, Kim J, Mao JH, Jablons D, Balmain A. PMID: 23591868.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    46. Ptch1 overexpression drives skin carcinogenesis and developmental defects in K14Ptch(FVB) mice. J Invest Dermatol. 2013 May; 133(5):1311-20. Kang HC, Wakabayashi Y, Jen KY, Mao JH, Zoumpourlis V, Del Rosario R, Balmain A. PMID: 23223138.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    47. Reliability of whole slide images as a diagnostic modality for renal allograft biopsies. Hum Pathol. 2013 May; 44(5):888-94. Jen KY, Olson JL, Brodsky S, Zhou XJ, Nadasdy T, Laszik ZG. PMID: 23199528.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    48. Pten regulates Aurora-A and cooperates with Fbxw7 in modulating radiation-induced tumor development. Mol Cancer Res. 2012 Jun; 10(6):834-44. Kwon YW, Kim IJ, Wu D, Lu J, Stock WA, Liu Y, Huang Y, Kang HC, DelRosario R, Jen KY, Perez-Losada J, Wei G, Balmain A, Mao JH. PMID: 22513362.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    49. Sequential mutations in Notch1, Fbxw7, and Tp53 in radiation-induced mouse thymic lymphomas. Blood. 2012 Jan 19; 119(3):805-9. Jen KY, Song IY, Banta KL, Wu D, Mao JH, Balmain A. PMID: 22117044.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    50. C4d/CD34 double-immunofluorescence staining of renal allograft biopsies for assessing peritubular capillary C4d positivity. Mod Pathol. 2012 Mar; 25(3):434-8. Jen KY, Nguyen TB, Vincenti FG, Laszik ZG. PMID: 22037262.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    51. Kidney microvasculature in health and disease. Contrib Nephrol. 2011; 169:51-72. Jen KY, Haragsim L, Laszik ZG. PMID: 21252511.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    52. Deletion of the PER3 gene on chromosome 1p36 in recurrent ER-positive breast cancer. J Clin Oncol. 2010 Aug 10; 28(23):3770-8. Climent J, Perez-Losada J, Quigley DA, Kim IJ, Delrosario R, Jen KY, Bosch A, Lluch A, Mao JH, Balmain A. PMID: 20625127.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    53. Identification of novel p53 target genes in ionizing radiation response. Cancer Res. 2005 Sep 01; 65(17):7666-73. Jen KY, Cheung VG. PMID: 16140933.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    54. Oxetane modified, conformationally constrained, antisense oligodeoxyribonucleotides function efficiently as gene silencing molecules. Nucleic Acids Res. 2004; 32(19):5791-9. Opalinska JB, Kalota A, Gifford LK, Lu P, Jen KY, Pradeepkumar PI, Barman J, Kim TK, Swider CR, Chattopadhyaya J, Gewirtz AM. PMID: 15514112.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    55. Transcriptional response of lymphoblastoid cells to ionizing radiation. Genome Res. 2003 Sep; 13(9):2092-100. Jen KY, Cheung VG. PMID: 12915489.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    56. Natural variation in human gene expression assessed in lymphoblastoid cells. Nat Genet. 2003 Mar; 33(3):422-5. Cheung VG, Conlin LK, Weber TM, Arcaro M, Jen KY, Morley M, Spielman RS. PMID: 12567189.
      View in: PubMed   Mentions: 257     Fields:    Translation:HumansCells
    57. Genetics of quantitative variation in human gene expression. Cold Spring Harb Symp Quant Biol. 2003; 68:403-7. Cheung VG, Jen KY, Weber T, Morley M, Devlin JL, Ewens KG, Spielman RS. PMID: 15338642.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    58. Hop is an unusual homeobox gene that modulates cardiac development. Cell. 2002 Sep 20; 110(6):713-23. Chen F, Kook H, Milewski R, Gitler AD, Lu MM, Li J, Nazarian R, Schnepp R, Jen K, Biben C, Runke G, Mackay JP, Novotny J, Schwartz RJ, Harvey RP, Mullins MC, Epstein JA. PMID: 12297045.
      View in: PubMed   Mentions: 84     Fields:    Translation:AnimalsCells
    59. Suppression of gene expression by targeted disruption of messenger RNA: available options and current strategies. Stem Cells. 2000; 18(5):307-19. Jen KY, Gewirtz AM. PMID: 11007915.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
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