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Implications of the Regulation of Endothelial Glycocalyx Breakdown and Reconstitution in Severe Burn Injury. J Surg Res. 2023 06; 286:110-117.
Basas VA, Schutzman LM, Brown IE. PMID: 36804690.
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HumansCells
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Emergency department visit patterns in the recently discharged, violently injured patient: Retrospective cohort review. Am J Surg. 2022 Jul 20.
Kleber KT, Kravitz-Wirtz N, Buggs SL, Adams CM, Sardo AC, Hoch JS, Brown IE. PMID: 35871849.
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The hidden mortality of pediatric firearm violence. J Pediatr Surg. 2022 May; 57(5):897-902.
Theodorou CM, Beyer CA, Vanover MA, Brown IE, Salcedo ES, Farmer DL, Hirose S, Beres AL. PMID: 35093255.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Getting around the gut: a unique management challenge of thyroid storm precipitated by amphetamine-associated duodenal ischaemia leading to compromised enteric absorption. BMJ Case Rep. 2021 Aug 19; 14(8).
Lee JSG, Brown IE, Semrad AM, Zeki AA. PMID: 34413029; PMCID: PMC8378395.
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Humans
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Viscoelastic Coagulation Monitor (VCMVet) Reference Intervals and Sex Differences in Mature Adult Mice. Acta Haematol. 2021; 144(6):633-640.
Rigor RR, Schutzman LM, Galante JM, Brown IE. PMID: 34237720.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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P-selectin antibody treatment after blunt thoracic trauma prevents early pulmonary arterial thrombosis without changes in viscoelastic measurements of coagulation. J Trauma Acute Care Surg. 2021 06 01; 90(6):1032-1039.
Schutzman LM, Rigor RR, Lin YJ, Dang AN, Le PH, Singh HB, Yu B, Wisner PH, Musson CC, Clark IJ, Galante JM, Brown IE. PMID: 34016926.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
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High Versus Low Volume Fluid Resuscitation Strategies in a Porcine Model (Sus scrofa) of Combined Thermal and Traumatic Brain Injury. Shock. 2021 04 01; 55(4):536-544.
Guenther TM, Spruce MW, Bach LM, Caples CM, Beyer CA, Grayson JK, Meyers FJ, Palmieri TL, Brown IE. PMID: 32881757.
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Animals
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Comment on "The Long-term Risk of Venous Thromboembolism After Blunt Splenic Injury Managed by Embolization". Ann Surg. 2020 03; 271(3):e101.
Brown IE. PMID: 32079831.
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Humans
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Donor Characteristics, Recipient Outcomes, and Histologic Findings of Kidney Allografts With Diffuse Donor-derived Glomerular Fibrin Thrombi. Transplantation. 2019 09; 103(9):1921-1927.
Gao G, Chen LX, Brown IE, De Mattos A, Perez RV, Jen KY. PMID: 30720684.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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P-Selectin Is Critical for De Novo Pulmonary Arterial Thrombosis Following Blunt Thoracic Trauma. J Trauma Acute Care Surg. 2019 04; 86(4):583-591.
Schutzman LM, Rigor RR, Khosravi N, Galante JM, Brown IE. PMID: 30562326.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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Pulmonary Arterial Thrombosis in a Murine Model of Blunt Thoracic Trauma. Shock. 2018 12; 50(6):696-705.
Brown IE, Rigor RR, Schutzman LM, Khosravi N, Chung K, Becker JA, Pivetti CD, Best GT, Chavez JC, Galante JM. PMID: 29394242.
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2 Fields:
Translation:
Animals
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Nonocclusive mesenteric ischemia in patients with methamphetamine use. J Trauma Acute Care Surg. 2018 06; 84(6):885-892.
Anderson JE, Brown IE, Olson KA, Iverson K, Cocanour CS, Galante JM. PMID: 29462085.
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12 Fields:
Translation:
Humans
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Partial resuscitative balloon occlusion of the aorta (P-REBOA): Clinical technique and rationale. J Trauma Acute Care Surg. 2016 11; 81(5 Suppl 2 Proceedings of the 2015 Military Health System Research Symposium):S133-S137.
Johnson MA, Neff LP, Williams TK, DuBose JJ, EVAC Study Group. PMID: 27244578; PMCID: PMC8789541.
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27 Fields:
Translation:
Humans
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Pelvic angioembolization in trauma - Indications and outcomes. Int J Surg. 2016 Sep; 33(Pt B):231-236.
Salcedo ES, Brown IE, Corwin MT, Galante JM. PMID: 26912018.
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8 Fields:
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Angioembolization for solid organ injury: A brief review. Int J Surg. 2016 Sep; 33(Pt B):225-230.
Salcedo ES, Brown IE, Corwin MT, Galante JM. PMID: 26537314.
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PubMed Mentions:
9 Fields:
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Low-dose cyclophosphamide improves survival in a murine treatment model of sepsis. Shock. 2015 Jan; 43(1):92-8.
Brown I, Bellevue O, Shawo A, Woldesemayat H, Lyo V, Rayikanti B, Lee M, Uzosike ED, Kasravi S, Harris HW. PMID: 25243421; PMCID: PMC4269572.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Tissue plasminogen activator (rt-PA) in acute ischemic stroke: Outcomes associated with ambulation. Restor Neurol Neurosci. 2015; 33(3):301-8.
Lawson TR, Brown IE, Westerkam DL, Blackhurst DW, Sternberg S, Leacock R, Nathaniel TI. PMID: 25698111.
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15 Fields:
Translation:
Humans
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Regular exercise attenuates the metabolic drive to regain weight after long-term weight loss. Am J Physiol Regul Integr Comp Physiol. 2009 Sep; 297(3):R793-802.
MacLean PS, Higgins JA, Wyatt HR, Melanson EL, Johnson GC, Jackman MR, Giles ED, Brown IE, Hill JO. PMID: 19587114; PMCID: PMC2739786.
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PubMed Mentions:
40 Fields:
Translation:
AnimalsCells
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Homeostatic proliferation plus regulatory T-cell depletion promotes potent rejection of B16 melanoma. Clin Cancer Res. 2008 May 15; 14(10):3156-67.
Kline J, Brown IE, Zha YY, Blank C, Strickler J, Wouters H, Zhang L, Gajewski TF. PMID: 18483384.
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PubMed Mentions:
56 Fields:
Translation:
AnimalsCells
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T cell anergy is reversed by active Ras and is regulated by diacylglycerol kinase-alpha. Nat Immunol. 2006 Nov; 7(11):1166-73.
Zha Y, Marks R, Ho AW, Peterson AC, Janardhan S, Brown I, Praveen K, Stang S, Stone JC, Gajewski TF. PMID: 17028589.
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PubMed Mentions:
141 Fields:
Translation:
AnimalsCells
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Immune resistance orchestrated by the tumor microenvironment. Immunol Rev. 2006 Oct; 213:131-45.
Gajewski TF, Meng Y, Blank C, Brown I, Kacha A, Kline J, Harlin H. PMID: 16972901.
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PubMed Mentions:
216 Fields:
Translation:
HumansAnimalsCells
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Homeostatic proliferation as an isolated variable reverses CD8+ T cell anergy and promotes tumor rejection. J Immunol. 2006 Oct 01; 177(7):4521-9.
Brown IE, Blank C, Kline J, Kacha AK, Gajewski TF. PMID: 16982889.
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PubMed Mentions:
48 Fields:
Translation:
AnimalsCells
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Cross-priming of T cells to intracranial tumor antigens elicits an immune response that fails in the effector phase but can be augmented with local immunotherapy. J Neuroimmunol. 2006 May; 174(1-2):74-81.
Velicu S, Han Y, Ulasov I, Brown IE, El Andaloussi A, Gajewski TF, Lesniak MS. PMID: 16504307.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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CD40 ligation restores cytolytic T lymphocyte response and eliminates fibrosarcoma in the peritoneum of mice lacking CD4+ T cells. Cancer Immunol Immunother. 2006 Dec; 55(12):1542-52.
Lodge A, Yu P, Nicholl MB, Brown IE, Jackson CC, Schreiber K, Sugg SL, Schreiber H, Shilyansky J. PMID: 16491399.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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ICAM-1 contributes to but is not essential for tumor antigen cross-priming and CD8+ T cell-mediated tumor rejection in vivo. J Immunol. 2005 Mar 15; 174(6):3416-20.
Blank C, Brown I, Kacha AK, Markiewicz MA, Gajewski TF. PMID: 15749875.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Peripheral survival of naïve CD8+ T cells. Apoptosis. 2005 Jan; 10(1):5-11.
Brown IE, Mashayekhi M, Markiewicz M, Alegre ML, Gajewski TF. PMID: 15711917.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Restored immune response to an MHC-II-Restricted antigen in tumor-bearing hosts after elimination of regulatory T cells. J Pediatr Surg. 2004 Jun; 39(6):941-6; discussion 941-6.
Nicholl M, Lodge A, Brown I, Sugg SL, Shilyansky J. PMID: 15185230.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCellsPHPublic Health
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PD-L1/B7H-1 inhibits the effector phase of tumor rejection by T cell receptor (TCR) transgenic CD8+ T cells. Cancer Res. 2004 Feb 01; 64(3):1140-5.
Blank C, Brown I, Peterson AC, Spiotto M, Iwai Y, Honjo T, Gajewski TF. PMID: 14871849.
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PubMed Mentions:
350 Fields:
Translation:
AnimalsCells
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Absence of programmed death receptor 1 alters thymic development and enhances generation of CD4/CD8 double-negative TCR-transgenic T cells. J Immunol. 2003 Nov 01; 171(9):4574-81.
Blank C, Brown I, Marks R, Nishimura H, Honjo T, Gajewski TF. PMID: 14568931.
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PubMed Mentions:
44 Fields:
Translation:
AnimalsCells
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Death of peripheral CD8+ T cells in the absence of MHC class I is Fas-dependent and not blocked by Bcl-xL. Eur J Immunol. 2003 Oct; 33(10):2917-26.
Markiewicz MA, Brown I, Gajewski TF. PMID: 14515276.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Cutting edge: targeted ligation of CTLA-4 in vivo by membrane-bound anti-CTLA-4 antibody prevents rejection of allogeneic cells. J Immunol. 2002 Jul 15; 169(2):633-7.
Hwang KW, Sweatt WB, Brown IE, Blank C, Gajewski TF, Bluestone JA, Alegre ML. PMID: 12097362.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells