Baback Roshanravan

Title(s)Professor, MED: Int Med Nephrology
SchoolSchool of Medicine
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    Title(s)Professor in Residence, MED: Int Med Nephrology


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    Impact of metabolic acidosis on muscle mitochondrial energetics, metabolic health and physical endurance in persons with chronic kidney disease
    NIH R01DK129793Aug 18, 2021 - Jun 30, 2026
    Role: Principal Investigator
    Mitochondrial bioenergetics in persons with chronic kidney disease
    NIH R03DK114502Apr 1, 2018 - Mar 31, 2021
    Role: Principal Investigator
    Skeletal muscle dysfunction in persons with chronic kidney disease
    NIH K23DK099442Sep 30, 2013 - Jun 30, 2020
    Role: Principal Investigator
    Skeletal muscle function and mitochondrial metabolism in non-diabetic CKD
    NIH F32DK093235Dec 1, 2012 - Sep 29, 2013
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Packed Red Blood Cell and Whole Blood Perfusates during Ex-Vivo Normothermic Perfusion for Assessment of High-Risk Donor Kidneys. Kidney360. 2025 May 07. Ahmadi A, Yang H, Jen KY, Fan S, Palma I, Sageshima J, Goussous N, Roshanravan B, Perez RV. PMID: 40333014.
      View in: PubMed   Mentions:    Fields:    
    2. Intermuscular Adipose Tissue in Chronic Kidney Disease: A Window into Muscle Quality and Health? Clin J Am Soc Nephrol. 2025 Apr 30. Demirci M, Dilaver RG, Roshanravan B, Ikizler TA, Gamboa JL. PMID: 40305132.
      View in: PubMed   Mentions:    Fields:    
    3. From Frailty to Fitness: Unraveling Mortality Risk in ESKD. Clin J Am Soc Nephrol. 2025 Mar 01; 20(3):320-322. Begue G, Roshanravan B. PMID: 39928418; PMCID: PMC11906001.
      View in: PubMed   Mentions:    Fields:    
    4. INTERMUSCULAR ADIPOSE TISSUE AND MUSCLE FUNCTION IN PATIENTS ON MAINTENANCE HEMODIALYSIS. medRxiv. 2025 Feb 02. Dilaver RG, Demirci M, Crescenzi R, Pridmore M, Ertuglu LA, Guide A, Greevy R, Roshanravan B, Ikizler TA, Gamboa JL. PMID: 39974089; PMCID: PMC11838629.
      View in: PubMed   Mentions:
    5. A Pilot Trial of Nicotinamide Riboside and Coenzyme Q10 on Inflammation and Oxidative Stress in CKD. Clin J Am Soc Nephrol. 2025 Mar 01; 20(3):346-357. Ahmadi A, Valencia AP, Begue G, Norman JE, Fan S, Durbin-Johnson BP, Jenner BN, Campbell MD, Reyes G, Kapahi P, Himmelfarb J, de Boer IH, Marcinek DJ, Kestenbaum BR, Gamboa JL, Roshanravan B. PMID: 39847432; PMCID: PMC11905997.
      View in: PubMed   Mentions:    Fields:    
    6. An ergometer dataset to measure muscle bioenergetics with magnetic resonance techniques. Data Brief. 2024 Dec; 57:111114. Rehman U, Begue G, Ahmadi A, Taboga P, Gamboa J, Roshanravan B, Jue T. PMID: 39640409; PMCID: PMC11617988.
      View in: PubMed   Mentions:
    7. Dialysis modality and quality of life: more answers yet more questions. Kidney Int. 2024 Nov; 106(5):792-794. Hamdan H, Roshanravan B. PMID: 39428172.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Impaired Incretin Homeostasis in Nondiabetic Moderate-to-Severe CKD. Clin J Am Soc Nephrol. 2025 Jan 01; 20(1):12-22. Ahmadi A, Gamboa J, Norman JE, Enkhmaa B, Tucker M, Bennett BJ, Zelnick LR, Fan S, Berglund LF, Ikizler TA, de Boer IH, Cummings BP, Roshanravan B. PMID: 39480994; PMCID: PMC11737449.
      View in: PubMed   Mentions:    Fields:    
    9. Randomized Crossover Clinical Trial of Nicotinamide Riboside and Coenzyme Q10 on Metabolic Health and Mitochondrial Bioenergetics in CKD. medRxiv. 2024 Aug 23. Ahmadi A, Valencia AP, Begue G, Norman JE, Fan S, Durbin-Johnson BP, Jenner BN, Campbell MD, Reyes G, Kapahi P, Himmelfarb J, de Boer IH, Marcinek DJ, Kestenbaum BR, Gamboa JL, Roshanravan B. PMID: 39228730; PMCID: PMC11370499.
      View in: PubMed   Mentions:
    10. Review of Exercise Interventions to Improve Clinical Outcomes in Nondialysis CKD. Kidney Int Rep. 2024 Nov; 9(11):3097-3115. Hayden CMT, Begue G, Gamboa JL, Baar K, Roshanravan B. PMID: 39534200; PMCID: PMC11551061.
      View in: PubMed   Mentions: 1  
    11. Deceased donor kidney function and branched chain amino acid metabolism during ex vivo normothermic perfusion. Kidney Int. 2024 Oct; 106(4):712-722. Ahmadi A, Yu J, Loza JE, Howard BC, Palma I, Goussous N, Sageshima J, Roshanravan B, Perez RV. PMID: 39074554; PMCID: PMC11908963.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Impaired incretin homeostasis in non-diabetic moderate-severe CKD. medRxiv. 2023 Dec 18. Ahmadi A, Gamboa J, Norman JE, Enkhmaa B, Tucker M, Bennett BJ, Zelnick LR, Fan S, Berglund LF, Ikizler TA, de Boer IH, Cummings BP, Roshanravan B. PMID: 38196612; PMCID: PMC10775324.
      View in: PubMed   Mentions:
    13. Randomized crossover clinical trial of coenzyme Q10 and nicotinamide riboside in chronic kidney disease. JCI Insight. 2023 06 08; 8(11). Ahmadi A, Begue G, Valencia AP, Norman JE, Lidgard B, Bennett BJ, Van Doren MP, Marcinek DJ, Fan S, Prince DK, Gamboa J, Himmelfarb J, de Boer IH, Kestenbaum BR, Roshanravan B. PMID: 37159264; PMCID: PMC10393227.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    14. Dissecting the Obesity Paradox in Patients With Obesity and CKD. Kidney Int Rep. 2023 Jul; 8(7):1281-1282. Alzayer H, Roshanravan B. PMID: 37441481; PMCID: PMC10334383.
      View in: PubMed   Mentions: 2  
    15. Chronic Kidney Disease is Associated With Attenuated Plasma Metabolome Response to Oral Glucose Tolerance Testing. J Ren Nutr. 2023 03; 33(2):316-325. Ahmadi A, Huda MN, Bennett BJ, Gamboa J, Zelnick LR, Smith LR, Chondronikola M, Raftery D, de Boer IH, Roshanravan B. PMID: 36270479; PMCID: PMC11196097.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    16. GFR Estimation in Potential Living Kidney Donors: Race- and Nonrace-based Equations and Measured GFR. Kidney Med. 2022 Dec; 4(12):100558. Goodson DA, Chalupsky MR, Wiegley N, Huang Y, Chiu M, Bang H, Roshanravan B, Young BY, Chen LX. PMID: 36471819; PMCID: PMC9719087.
      View in: PubMed   Mentions: 2  
    17. Effects of caloric restriction and aerobic exercise on circulating cell-free mitochondrial DNA in patients with moderate to severe chronic kidney disease. Am J Physiol Renal Physiol. 2022 01 01; 322(1):F68-F75. Jaramillo-Morales J, Korucu B, Pike MM, Lipworth L, Stewart T, Headley SAE, Germain M, Begue G, Roshanravan B, Tuttle KR, Himmelfarb J, Robinson-Cohen C, Ikizler TA, Gamboa JL. PMID: 34843657; PMCID: PMC8742721.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    18. Global Policy Barriers and Enablers to Exercise and Physical Activity in Kidney Care. J Ren Nutr. 2022 07; 32(4):441-449. Bennett PN, Kohzuki M, Bohm C, Roshanravan B, Bakker SJL, Viana JL, MacRae JM, Wilkinson TJ, Wilund KR, Van Craenenbroeck AH, Sakkas GK, Mustata S, Fowler K, McDonald J, Aleamañy GM, Anding K, Avin KG, Escobar GL, Gabrys I, Goth J, Isnard M, Jhamb M, Kim JC, Li JW, Lightfoot CJ, McAdams-DeMarco M, Manfredini F, Meade A, Molsted S, Parker K, Seguri-Orti E, Smith AC, Verdin N, Zheng J, Zimmerman D, Thompson S, Global Renal Exercise Network (GREX). PMID: 34393071; PMCID: PMC10505947.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    19. In vivo mitochondrial ATP production is improved in older adult skeletal muscle after a single dose of elamipretide in a randomized trial. PLoS One. 2021; 16(7):e0253849. Roshanravan B, Liu SZ, Ali AS, Shankland EG, Goss C, Amory JK, Robertson HT, Marcinek DJ, Conley KE. PMID: 34264994; PMCID: PMC8282018.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    20. Astaxanthin supplementation enhances metabolic adaptation with aerobic training in the elderly. Physiol Rep. 2021 06; 9(11):e14887. Liu SZ, Valencia AP, VanDoren MP, Shankland EG, Roshanravan B, Conley KE, Marcinek DJ. PMID: 34110707; PMCID: PMC8191397.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    21. New insights into muscle function in chronic kidney disease and metabolic acidosis. Curr Opin Nephrol Hypertens. 2021 05 01; 30(3):369-376. Chalupsky M, Goodson DA, Gamboa JL, Roshanravan B. PMID: 33767065.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    22. Moving beyond Sedentarism in CKD. Clin J Am Soc Nephrol. 2021 05 08; 16(5):674-676. Kim TY, Roshanravan B. PMID: 33888537; PMCID: PMC8259495.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    23. Determinants of Health-Related Quality of Life and Physical Performance-Based Components of Frailty in Patients Undergoing Hemodialysis. J Ren Nutr. 2021 Sep; 31(5):529-536. Matsuzawa R, Suzuki Y, Yamamoto S, Harada M, Watanabe T, Shimoda T, Yoshida A, Delgado C, Tamaki A, Matsunaga A, Roshanravan B. PMID: 32981832; PMCID: PMC9621716.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    24. Dissecting the Genetic Architecture of Cystatin C in Diversity Outbred Mice. G3 (Bethesda). 2020 07 07; 10(7):2529-2541. Huda MN, VerHague M, Albright J, Smallwood T, Bell TA, Que E, Miller DR, Roshanravan B, Allayee H, Manuel de Villena FP, Bennett BJ. PMID: 32467129; PMCID: PMC7341122.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    25. Skeletal Muscle Mitochondrial Dysfunction Is Present in Patients with CKD before Initiation of Maintenance Hemodialysis. Clin J Am Soc Nephrol. 2020 07 01; 15(7):926-936. Gamboa JL, Roshanravan B, Towse T, Keller CA, Falck AM, Yu C, Frontera WR, Brown NJ, Ikizler TA. PMID: 32591419; PMCID: PMC7341789.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    26. Impaired skeletal muscle mitochondrial bioenergetics and physical performance in chronic kidney disease. JCI Insight. 2020 03 12; 5(5). Kestenbaum B, Gamboa J, Liu S, Ali AS, Shankland E, Jue T, Giulivi C, Smith LR, Himmelfarb J, de Boer IH, Conley K, Roshanravan B. PMID: 32161192; PMCID: PMC7141399.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    27. Assessment of physical functioning in the clinical care of the patient with advanced kidney disease. Semin Dial. 2019 07; 32(4):351-360. Roshanravan B, Patel KV. PMID: 31044471; PMCID: PMC6606347.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    28. Decline in the Functional Status and Mortality in Patients on Hemodialysis: Results from the Japan Dialysis Outcome and Practice Patterns Study. J Ren Nutr. 2019 11; 29(6):504-510. Matsuzawa R, Kamitani T, Roshanravan B, Fukuma S, Joki N, Fukagawa M. PMID: 30591357; PMCID: PMC6591104.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    29. Building strength, endurance, and mobility using an astaxanthin formulation with functional training in elderly. J Cachexia Sarcopenia Muscle. 2018 10; 9(5):826-833. Liu SZ, Ali AS, Campbell MD, Kilroy K, Shankland EG, Roshanravan B, Marcinek DJ, Conley KE. PMID: 30259703; PMCID: PMC6204600.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    30. Chronic kidney disease attenuates the plasma metabolome response to insulin. JCI Insight. 2018 08 23; 3(16). Roshanravan B, Zelnick LR, Djucovic D, Gu H, Alvarez JA, Ziegler TR, Gamboa JL, Utzschneider K, Kestenbaum B, Himmelfarb J, Kahn SE, Raftery D, de Boer IH. PMID: 30135309; PMCID: PMC6141172.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCellsCTClinical Trials
    31. Management of Physical Frailty in Patients Requiring Hemodialysis Therapy. Contrib Nephrol. 2018; 196:101-109. Matsuzawa R, Roshanravan B. PMID: 30041212.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    32. Physical Activity Dose for Hemodialysis Patients: Where to Begin? Results from a Prospective Cohort Study. J Ren Nutr. 2018 01; 28(1):45-53. Matsuzawa R, Roshanravan B, Shimoda T, Mamorita N, Yoneki K, Harada M, Watanabe T, Yoshida A, Takeuchi Y, Matsunaga A. PMID: 28893466; PMCID: PMC6365108.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    33. Exercise and CKD: Skeletal Muscle Dysfunction and Practical Application of Exercise to Prevent and Treat Physical Impairments in CKD. Am J Kidney Dis. 2017 Jun; 69(6):837-852. Roshanravan B, Gamboa J, Wilund K. PMID: 28427790; PMCID: PMC5441955.
      View in: PubMed   Mentions: 87     Fields:    Translation:Humans
    34. Association of Muscle Endurance, Fatigability, and Strength With Functional Limitation and Mortality in the Health Aging and Body Composition Study. J Gerontol A Biol Sci Med Sci. 2017 02; 72(2):284-291. Roshanravan B, Patel KV, Fried LF, Robinson-Cohen C, de Boer IH, Harris T, Murphy RA, Satterfield S, Goodpaster BH, Shlipak M, Newman AB, Kestenbaum B, Health ABC study. PMID: 27907890; PMCID: PMC5233917.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    35. CKD and Muscle Mitochondrial Energetics. Am J Kidney Dis. 2016 10; 68(4):658-659. Roshanravan B, Kestenbaum B, Gamboa J, Jubrias SA, Ayers E, Curtin L, Himmelfarb J, de Boer IH, Conley KE. PMID: 27312460; PMCID: PMC5063821.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    36. Mitochondrial dysfunction and oxidative stress in patients with chronic kidney disease. Physiol Rep. 2016 May; 4(9). Gamboa JL, Billings FT, Bojanowski MT, Gilliam LA, Yu C, Roshanravan B, Roberts LJ, Himmelfarb J, Ikizler TA, Brown NJ. PMID: 27162261; PMCID: PMC4873632.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansAnimalsCells
    37. Coenzyme Q10 dose-escalation study in hemodialysis patients: safety, tolerability, and effect on oxidative stress. BMC Nephrol. 2015 Nov 03; 16:183. Yeung CK, Billings FT, Claessens AJ, Roshanravan B, Linke L, Sundell MB, Ahmad S, Shao B, Shen DD, Ikizler TA, Himmelfarb J. PMID: 26531095; PMCID: PMC4630830.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansPHPublic Health
    38. Gait Speed in Patients With Kidney Failure Treated With Long-term Dialysis. Am J Kidney Dis. 2015 Aug; 66(2):190-2. Roshanravan B. PMID: 26210725; PMCID: PMC4905695.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    39. Longitudinal association between serum leptin concentration and glomerular filtration rate in humans. PLoS One. 2015; 10(2):e0117828. Pedone C, Roshanravan B, Scarlata S, Patel KV, Ferrucci L, Incalzi RA. PMID: 25710704; PMCID: PMC4339378.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    40. Creatinine clearance, walking speed, and muscle atrophy: a cohort study. Am J Kidney Dis. 2015 May; 65(5):737-47. Roshanravan B, Patel KV, Robinson-Cohen C, de Boer IH, O'Hare AM, Ferrucci L, Himmelfarb J, Kestenbaum B. PMID: 25542415; PMCID: PMC4414665.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    41. Changes in symptom burden and physical performance with initiation of dialysis in patients with chronic kidney disease. Hemodial Int. 2015 Jan; 19(1):147-50. Rivara MB, Robinson-Cohen C, Kestenbaum B, Roshanravan B, Chen CH, Himmelfarb J, Mehrotra R. PMID: 25404416; PMCID: PMC4420177.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    42. Frailty in CKD--is only seeing worth believing? Am J Kidney Dis. 2014 Oct; 64(4):489-91. Roshanravan B. PMID: 25257324; PMCID: PMC4304660.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    43. The association of physical activity and physical function with clinical outcomes in adults with chronic kidney disease. Curr Opin Nephrol Hypertens. 2013 Nov; 22(6):615-23. Painter P, Roshanravan B. PMID: 24100215.
      View in: PubMed   Mentions: 64     Fields:    Translation:Humans
    44. Association between physical performance and all-cause mortality in CKD. J Am Soc Nephrol. 2013 Apr; 24(5):822-30. Roshanravan B, Robinson-Cohen C, Patel KV, Ayers E, Littman AJ, de Boer IH, Ikizler TA, Himmelfarb J, Katzel LI, Kestenbaum B, Seliger S. PMID: 23599380; PMCID: PMC3636794.
      View in: PubMed   Mentions: 183     Fields:    Translation:Humans
    45. A prospective study of frailty in nephrology-referred patients with CKD. Am J Kidney Dis. 2012 Dec; 60(6):912-21. Roshanravan B, Khatri M, Robinson-Cohen C, Levin G, Patel KV, de Boer IH, Seliger S, Ruzinski J, Himmelfarb J, Kestenbaum B. PMID: 22770927; PMCID: PMC3491110.
      View in: PubMed   Mentions: 146     Fields:    Translation:Humans
    46. Assessment of physical activity in chronic kidney disease. J Ren Nutr. 2013 Mar; 23(2):123-31. Robinson-Cohen C, Littman AJ, Duncan GE, Roshanravan B, Ikizler TA, Himmelfarb J, Kestenbaum BR. PMID: 22739659; PMCID: PMC3496802.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    47. Endemic malaria in the Peruvian Amazon region of Iquitos. Am J Trop Med Hyg. 2003 Jul; 69(1):45-52. Roshanravan B, Kari E, Gilman RH, Cabrera L, Lee E, Metcalfe J, Calderon M, Lescano AG, Montenegro SH, Calampa C, Vinetz JM. PMID: 12932096.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsPHPublic Health
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