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Deconvoluting Nonlinear Catalyst-Substrate Effects in the Intramolecular Dirhodium-Catalyzed C-H Insertion of Donor/Donor Carbenes Using Data Science Tools. ACS Catal. 2024 Jan 05; 14(1):104-115.
Souza LW, Miller BR, Cammarota RC, Lo A, Lopez I, Shiue YS, Bergstrom BD, Dishman SN, Fettinger JC, Sigman MS, Shaw JT. PMID: 38205021; PMCID: PMC10775150.
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PubMed Mentions:
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Catalytic generation of ortho-quinone dimethides via donor/donor rhodium carbenes. Chem Sci. 2023 Jun 14; 14(23):6443-6448.
Gao M, Ruiz JM, Jimenez E, Lo A, Laconsay CJ, Fettinger JC, Tantillo DJ, Shaw JT. PMID: 37325151; PMCID: PMC10266466.
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One-Pot Assembly and Synthetic Applications of Geminal Acyl/Alkoxy Tetrasubstituted Allenes. J Org Chem. 2022 09 16; 87(18):12175-12181.
Bergstrom BD, Toth-Williams G, Lo A, Toman JW, Fettinger JC, Shaw JT. PMID: 36006876; PMCID: PMC10287019.
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PubMed Mentions: Fields:
Translation:
Cells
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Divergent Asymmetric Synthesis of Panowamycins, TM-135, and Veramycin F Using C-H Insertion with Donor/Donor Carbenes. Angew Chem Int Ed Engl. 2022 06 20; 61(25):e202203072.
Bergstrom BD, Merrill AT, Fettinger JC, Tantillo DJ, Shaw JT. PMID: 35381108; PMCID: PMC9189068.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
-
Diastereoselective Addition of Prochiral Nucleophilic Alkenes to α-Chiral N-Sulfonyl Imines. Org Lett. 2022 02 11; 24(5):1164-1168.
Gutierrez DA, Fettinger J, Houk KN, Ando K, Shaw JT. PMID: 35103474.
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PubMed Mentions:
1 Fields:
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1,3-Asymmetric Induction in Diastereoselective Allylations of Chiral N-Tosyl Imines. J Org Chem. 2022 03 04; 87(5):2773-2778.
Lo A, Gutierrez DA, Toth-Williams G, Fettinger JC, Shaw JT. PMID: 35029404.
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PubMed Mentions:
1 Fields:
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Divergent stereochemical outcomes in the insertion of donor/donor carbenes into the C-H bonds of stereogenic centers. Chem Sci. 2022 Jan 26; 13(4):1030-1036.
Dishman SN, Laconsay CJ, Fettinger JC, Tantillo DJ, Shaw JT. PMID: 35211269; PMCID: PMC8790770.
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PubMed Mentions:
3
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Mechanistic Investigation of Castagnoli-Cushman Multicomponent Reactions Leading to a Three-Component Synthesis of Dihydroisoquinolones. J Org Chem. 2021 09 03; 86(17):11599-11607.
Howard SY, Di Maso MJ, Shimabukuro K, Burlow NP, Tan DQ, Fettinger JC, Malig TC, Hein JE, Shaw JT. PMID: 34351161.
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PubMed Mentions:
6 Fields:
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Highly Sensitive and Selective Spiropyran-Based Sensor for Copper(II) Quantification. ACS Omega. 2021 Apr 27; 6(16):10776-10789.
Trevino KM, Tautges BK, Kapre R, Franco FC, Or VW, Balmond EI, Shaw JT, Garcia J, Louie AY. PMID: 34056232; PMCID: PMC8153370.
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PubMed Mentions:
2
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Comparison of Proteomic Responses as Global Approach to Antibiotic Mechanism of Action Elucidation. Antimicrob Agents Chemother. 2020 12 16; 65(1).
Senges CHR, Stepanek JJ, Wenzel M, Raatschen N, Ay Ü, Märtens Y, Prochnow P, Vázquez Hernández M, Yayci A, Schubert B, Janzing NBM, Warmuth HL, Kozik M, Bongard J, Alumasa JN, Albada B, Penkova M, Lukežic T, Sorto NA, Lorenz N, Miller RG, Zhu B, Benda M, Stülke J, Schäkermann S, Leichert LI, Scheinpflug K, Brötz-Oesterhelt H, Hertweck C, Shaw JT, Petkovic H, Brunel JM, Keiler KC, Metzler-Nolte N, Bandow JE. PMID: 33046497; PMCID: PMC7927858.
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PubMed Mentions:
13 Fields:
Translation:
Cells
-
Transition Metal Catalyzed Insertion Reactions with Donor/Donor Carbenes. Angew Chem Int Ed Engl. 2021 Mar 22; 60(13):6864-6878.
Bergstrom BD, Nickerson LA, Shaw JT, Souza LW. PMID: 32770624; PMCID: PMC7867669.
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PubMed Mentions:
22 Fields:
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Enantioselective Si-H Insertion Reactions of Diarylcarbenes for the Synthesis of Silicon-Stereogenic Silanes. J Am Chem Soc. 2020 07 08; 142(27):11674-11679.
Jagannathan JR, Fettinger JC, Shaw JT, Franz AK. PMID: 32539370; PMCID: PMC7747653.
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PubMed Mentions:
16 Fields:
Translation:
Cells
-
Synthesis and Comparative Evaluation of Photoswitchable Magnetic Resonance Imaging Contrast Agents. ACS Omega. 2020 Jun 23; 5(24):14759-14766.
Gao M, Shen B, Zhou J, Kapre R, Louie AY, Shaw JT. PMID: 32596613; PMCID: PMC7315594.
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PubMed Mentions:
2
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Effect of Structure and Intramolecular Distances on Photoswitchable Magnetic Resonance Imaging Contrast Agents. J Org Chem. 2020 06 05; 85(11):7333-7341.
Shen B, Gao M, Franco FC, Kapre R, Zhou J, Li X, Garcia J, Shaw JT, Louie AY. PMID: 32397710.
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PubMed Mentions: Fields:
-
Correction: Enantioselective synthesis of isochromans and tetrahydroisoquinolines by C-H insertion of donor/donor carbenes. Chem Sci. 2020 May 06; 11(19):5113.
Nickerson LA, Bergstrom BD, Gao M, Shiue YS, Laconsay CJ, Culberson MR, Knauss WA, Fettinger JC, Tantillo DJ, Shaw JT. PMID: 34122969; PMCID: PMC8159229.
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PubMed Mentions:
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C-H Insertion Reactions of Donor/Donor Carbenes: Inception, Investigation, and Insights. Synlett. 2020; 31(9):838-844.
Shaw JT. PMID: 34321717; PMCID: PMC8315035.
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PubMed Mentions:
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Enantioselective synthesis of isochromans and tetrahydroisoquinolines by C-H insertion of donor/donor carbenes. Chem Sci. 2020 Jan 14; 11(2):494-498.
Nickerson LA, Bergstrom BD, Gao M, Shiue YS, Laconsay CJ, Culberson MR, Knauss WA, Fettinger JC, Tantillo DJ, Shaw JT. PMID: 32874491; PMCID: PMC7439777.
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PubMed Mentions:
10
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Trapping and Electron Paramagnetic Resonance Characterization of the 5'dAdo• Radical in a Radical S-Adenosyl Methionine Enzyme Reaction with a Non-Native Substrate. ACS Cent Sci. 2019 Nov 27; 5(11):1777-1785.
Sayler RI, Stich TA, Joshi S, Cooper N, Shaw JT, Begley TP, Tantillo DJ, Britt RD. PMID: 31807679; PMCID: PMC6891858.
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PubMed Mentions:
27
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Synthesis of Spirobicyclic Pyrazoles by Intramolecular Dipolar Cycloadditions/[1s, 5s] Sigmatropic Rearrangements. Org Lett. 2019 09 20; 21(18):7209-7212.
Dimirjian CA, Castiñeira Reis M, Balmond EI, Turman NC, Rodriguez EP, Di Maso MJ, Fettinger JC, Tantillo DJ, Shaw JT. PMID: 31486651; PMCID: PMC6955098.
View in:
PubMed Mentions:
4 Fields:
Translation:
Cells
-
Acyclic Stereocontrol in the Additions of Nucleophilic Alkenes to α-Chiral N-Sulfonyl Imines. Chemistry. 2019 Sep 18; 25(52):12214-12220.
Moore LC, Lo A, Fell JS, Duong MR, Moreno JA, Rich BE, Bravo M, Fettinger JC, Souza LW, Olmstead MM, Houk KN, Shaw JT. PMID: 31226239.
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PubMed Mentions:
1 Fields:
-
Antioxidant Sensing by Spiropyrans: Substituent Effects and NMR Spectroscopic Studies. J Phys Chem B. 2019 08 08; 123(31):6799-6809.
Garcia J, Addison JB, Liu SZ, Lu S, Faulkner AL, Hodur BM, Balmond EI, Or VW, Yun JH, Trevino K, Shen B, Shaw JT, Frank NL, Louie AY. PMID: 31284715.
View in:
PubMed Mentions:
1 Fields:
Translation:
Cells
-
FtsZ-Independent Mechanism of Division Inhibition by the Small Molecule PC190723 in Escherichia coli. Adv Biosyst. 2019 11; 3(11):e1900021.
Khare S, Hsin J, Sorto NA, Nepomuceno GM, Shaw JT, Shi H, Huang KC. PMID: 32648693.
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PubMed Mentions:
3 Fields:
Translation:
Cells
-
Organocatalytic Mukaiyama Mannich Reactions of 2,5-Bis(trimethylsilyloxy)furan. Org Lett. 2019 07 05; 21(13):5073-5077.
Laws SW, Howard SY, Mato R, Meng S, Fettinger JC, Shaw JT. PMID: 31247788.
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PubMed Mentions:
4 Fields:
-
Formal [4 + 2] Cycloadditions of Anhydrides and α,β-Unsaturated N-Tosyl Ketimines. Org Lett. 2019 02 15; 21(4):1046-1049.
Burlow NP, Howard SY, Saunders CM, Fettinger JC, Tantillo DJ, Shaw JT. PMID: 30721078.
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PubMed Mentions:
1 Fields:
-
Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space. ACS Cent Sci. 2018 Dec 26; 4(12):1727-1741.
Kearney SE, Zahoránszky-Kohalmi G, Brimacombe KR, Henderson MJ, Lynch C, Zhao T, Wan KK, Itkin Z, Dillon C, Shen M, Cheff DM, Lee TD, Bougie D, Cheng K, Coussens NP, Dorjsuren D, Eastman RT, Huang R, Iannotti MJ, Karavadhi S, Klumpp-Thomas C, Roth JS, Sakamuru S, Sun W, Titus SA, Yasgar A, Zhang YQ, Zhao J, Andrade RB, Brown MK, Burns NZ, Cha JK, Mevers EE, Clardy J, Clement JA, Crooks PA, Cuny GD, Ganor J, Moreno J, Morrill LA, Picazo E, Susick RB, Garg NK, Goess BC, Grossman RB, Hughes CC, Johnston JN, Joullie MM, Kinghorn AD, Kingston DGI, Krische MJ, Kwon O, Maimone TJ, Majumdar S, Maloney KN, Mohamed E, Murphy BT, Nagorny P, Olson DE, Overman LE, Brown LE, Snyder JK, Porco JA, Rivas F, Ross SA, Sarpong R, Sharma I, Shaw JT, Xu Z, Shen B, Shi W, Stephenson CRJ, Verano AL, Tan DS, Tang Y, Taylor RE, Thomson RJ, Vosburg DA, Wu J, Wuest WM, Zakarian A, Zhang Y, Ren T, Zuo Z, Inglese J, Michael S, Simeonov A, Zheng W, Shinn P, Jadhav A, Boxer MB, Hall MD, Xia M, Guha R, Rohde JM. PMID: 30648156; PMCID: PMC6311695.
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PubMed Mentions:
20
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Enantioselective Synthesis of Indolines, Benzodihydrothiophenes, and Indanes by C-H Insertion of Donor/Donor Carbenes. Angew Chem Int Ed Engl. 2018 11 12; 57(46):15213-15216.
Souza LW, Squitieri RA, Dimirjian CA, Hodur BM, Nickerson LA, Penrod CN, Cordova J, Fettinger JC, Shaw JT. PMID: 30193007; PMCID: PMC6377237.
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PubMed Mentions:
11 Fields:
Translation:
Cells
-
Synthesis of Benzodihydrofurans by Asymmetric C-H Insertion Reactions of Donor/Donor Rhodium Carbenes. Chemistry. 2017 Sep 04; 23(49):11843-11855.
Lamb KN, Squitieri RA, Chintala SR, Kwong AJ, Balmond EI, Soldi C, Dmitrenko O, Castiñeira Reis M, Chung R, Addison JB, Fettinger JC, Hein JE, Tantillo DJ, Fox JM, Shaw JT. PMID: 28544228.
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PubMed Mentions:
14 Fields:
-
Diastereoselective Base-Catalyzed Formal [4 + 2] Cycloadditions of N-Sulfonyl Imines and Cyclic Anhydrides. Org Lett. 2017 05 19; 19(10):2466-2469.
Laws SW, Moore LC, Di Maso MJ, Nguyen QNN, Tantillo DJ, Shaw JT. PMID: 28474515; PMCID: PMC5576723.
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PubMed Mentions:
5 Fields:
-
Targeting quinolone- and aminocoumarin-resistant bacteria with new gyramide analogs that inhibit DNA gyrase. Medchemcomm. 2017; 8(5):942-951.
Hurley KA, Santos TMA, Fensterwald MR, Rajendran M, Moore JT, Balmond EI, Blahnik BJ, Faulkner KC, Foss MH, Heinrich VA, Lammers MG, Moore LC, Reynolds GD, Shearn-Nance GP, Stearns BA, Yao ZW, Shaw JT, Weibel DB. PMID: 30034678; PMCID: PMC6051542.
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PubMed Mentions:
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Asymmetric Synthesis of Homocitric Acid Lactone. J Org Chem. 2016 11 18; 81(22):11404-11408.
Nickerson LA, Huynh V, Balmond EI, Cramer SP, Shaw JT. PMID: 27685496; PMCID: PMC7190193.
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PubMed Mentions:
1 Fields:
Translation:
Cells
-
Comparative Evaluation of Substituent Effect on the Photochromic Properties of Spiropyrans and Spirooxazines. J Org Chem. 2016 10 07; 81(19):8744-8758.
Balmond EI, Tautges BK, Faulkner AL, Or VW, Hodur BM, Shaw JT, Louie AY. PMID: 27529635.
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PubMed Mentions:
13 Fields:
-
Plastidial metabolite MEcPP induces a transcriptionally centered stress-response hub via the transcription factor CAMTA3. Proc Natl Acad Sci U S A. 2016 08 02; 113(31):8855-60.
Benn G, Bjornson M, Ke H, De Souza A, Balmond EI, Shaw JT, Dehesh K. PMID: 27432993; PMCID: PMC4978302.
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PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
-
Synthesis of Esters by in Situ Formation and Trapping of Diazoalkanes. J Org Chem. 2016 07 01; 81(13):5278-84.
Squitieri RA, Shearn-Nance GP, Hein JE, Shaw JT. PMID: 27191835.
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PubMed Mentions:
4 Fields:
-
Synthesis of (±)-Bisavenanthramide B-6 by an Anionic Anhydride Mannich Reaction. Org Lett. 2016 Apr 15; 18(8):1740-3.
Di Maso MJ, Nepomuceno GM, St Peter MA, Gitre HH, Martin KS, Shaw JT. PMID: 27023166.
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PubMed Mentions:
5 Fields:
Translation:
Cells
-
Targeting the Bacterial Division Protein FtsZ. J Med Chem. 2016 Aug 11; 59(15):6975-98.
Hurley KA, Santos TM, Nepomuceno GM, Huynh V, Shaw JT, Weibel DB. PMID: 26756351.
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PubMed Mentions:
36 Fields:
Translation:
HumansCells
-
Diastereoselective Synthesis of and Mechanistic Understanding for the Formation of 2-Piperidinones from Imines and Cyano-Substituted Anhydrides. Chemistry. 2016 Mar 24; 22(14):4794-801.
Di Maso MJ, Snyder KM, De Souza Fernandes F, Pattawong O, Tan DQ, Fettinger JC, Cheong PH, Shaw JT. PMID: 26929008.
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PubMed Mentions:
6 Fields:
-
Toward Structural Correctness: Aquatolide and the Importance of 1D Proton NMR FID Archiving. J Org Chem. 2016 Feb 05; 81(3):878-89.
Pauli GF, Niemitz M, Bisson J, Lodewyk MW, Soldi C, Shaw JT, Tantillo DJ, Saya JM, Vos K, Kleinnijenhuis RA, Hiemstra H, Chen SN, McAlpine JB, Lankin DC, Friesen JB. PMID: 26812443; PMCID: PMC4746703.
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PubMed Mentions:
14 Fields:
Translation:
Cells
-
Preparation of a conjugation-ready thiol responsive molecular switch. Tetrahedron Lett. 2015 Nov 25; 56(47):6569-6573.
Tautges B, Or V, Garcia J, Shaw JT, Louie AY. PMID: 26594066; PMCID: PMC4649948.
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PubMed Mentions:
4 Fields:
-
Synthesis of the diaryl ether cores common to chrysophaentins A, E and F. Tetrahedron Lett. 2015 Jun 03; 56(23):3396-3401.
Brockway AJ, Grove CI, Mahoney ME, Shaw JT. PMID: 26034333; PMCID: PMC4448730.
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PubMed Mentions:
2 Fields:
-
Synthesis and Evaluation of Quinazolines as Inhibitors of the Bacterial Cell Division Protein FtsZ. ACS Med Chem Lett. 2015 Mar 12; 6(3):308-12.
Nepomuceno GM, Chan KM, Huynh V, Martin KS, Moore JT, O'Brien TE, Pollo LA, Sarabia FJ, Tadeus C, Yao Z, Anderson DE, Ames JB, Shaw JT. PMID: 25815151; PMCID: PMC4360151.
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PubMed Mentions:
7
-
Enantioselective intramolecular C-H insertion reactions of donor-donor metal carbenoids. J Am Chem Soc. 2014 Oct 29; 136(43):15142-5.
Soldi C, Lamb KN, Squitieri RA, González-López M, Di Maso MJ, Shaw JT. PMID: 25308822; PMCID: PMC4227726.
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PubMed Mentions:
35 Fields:
Translation:
Cells
-
Failsafe mechanisms couple division and DNA replication in bacteria. Curr Biol. 2014 Sep 22; 24(18):2149-2155.
Arjes HA, Kriel A, Sorto NA, Shaw JT, Wang JD, Levin PA. PMID: 25176632; PMCID: PMC4175050.
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PubMed Mentions:
21 Fields:
Translation:
Cells
-
Gyramides prevent bacterial growth by inhibiting DNA gyrase and altering chromosome topology. ACS Chem Biol. 2014 Jun 20; 9(6):1312-9.
Rajendram M, Hurley KA, Foss MH, Thornton KM, Moore JT, Shaw JT, Weibel DB. PMID: 24712739; PMCID: PMC4068256.
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PubMed Mentions:
9 Fields:
Translation:
Cells
-
Diastereoselective synthesis of γ- and δ-lactams from imines and sulfone-substituted anhydrides. J Org Chem. 2014 Mar 21; 79(6):2601-10.
Sorto NA, Di Maso MJ, Muñoz MA, Dougherty RJ, Fettinger JC, Shaw JT. PMID: 24552208; PMCID: PMC3977582.
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PubMed Mentions:
5 Fields:
Translation:
Cells
-
Enantioselective synthesis of isotopically labeled homocitric acid lactone. Org Lett. 2013 Nov 15; 15(22):5615-7.
Moore JT, Hanhan NV, Mahoney ME, Cramer SP, Shaw JT. PMID: 24180620; PMCID: PMC3932135.
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PubMed Mentions:
2 Fields:
Translation:
Cells
-
Stereocontrol in asymmetric γ-lactam syntheses from imines and cyanosuccinic anhydrides. Org Lett. 2013 Oct 04; 15(19):5130-3.
Pattawong O, Tan DQ, Fettinger JC, Shaw JT, Cheong PH. PMID: 24070216; PMCID: PMC3988202.
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PubMed Mentions:
9 Fields:
Translation:
Cells
-
Stereoselective synthesis of γ-lactams from imines and cyanosuccinic anhydrides. Org Lett. 2013 Oct 04; 15(19):5126-9.
Tan DQ, Younai A, Pattawong O, Fettinger JC, Cheong PH, Shaw JT. PMID: 24070117; PMCID: PMC3874237.
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PubMed Mentions:
6 Fields:
Translation:
Cells
-
Synthesis of a library of "lead-like" γ-lactams by a one pot, four-component reaction. ACS Comb Sci. 2013 Jul 08; 15(7):356-62.
Martin KS, Di Maso MJ, Fettinger JC, Shaw JT. PMID: 23682712; PMCID: PMC3816122.
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PubMed Mentions:
2 Fields:
-
Design and synthesis of mimics of the T7-loop of FtsZ. Org Lett. 2013 Jun 07; 15(11):2700-3.
Sorto NA, Painter PP, Fettinger JC, Tantillo DJ, Shaw JT. PMID: 23721122; PMCID: PMC3727220.
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PubMed Mentions:
1 Fields:
Translation:
Cells
-
Mechanism of alkoxy groups substitution by Grignard reagents on aromatic rings and experimental verification of theoretical predictions of anomalous reactions. J Am Chem Soc. 2013 May 01; 135(17):6633-42.
Jiménez-Osés G, Brockway AJ, Shaw JT, Houk KN. PMID: 23601086; PMCID: PMC3726219.
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PubMed Mentions:
5 Fields:
Translation:
Cells
-
From bead to flask: Synthesis of a complex β-amido-amide for probe-development studies. Beilstein J Org Chem. 2013; 9:260-4.
Martin KS, Soldi C, Candee KN, Wettersten HI, Weiss RH, Shaw JT. PMID: 23400429; PMCID: PMC3566855.
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PubMed Mentions:
-
The correct structure of aquatolide-experimental validation of a theoretically-predicted structural revision. J Am Chem Soc. 2012 Nov 14; 134(45):18550-3.
Lodewyk MW, Soldi C, Jones PB, Olmstead MM, Rita J, Shaw JT, Tantillo DJ. PMID: 23101682.
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PubMed Mentions:
33 Fields:
Translation:
AnimalsCells
-
Catalytic Alkene Cyclization Reactions for the Stereoselective Synthesis of Complex "Terpenoid-like" Heterocycles. Chem Sci. 2013 Jan 01; 4(1):292-296.
Moore JT, Soldi C, Fettinger JC, Shaw JT. PMID: 23565327; PMCID: PMC3614375.
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PubMed Mentions:
4
-
Comparison of small molecule inhibitors of the bacterial cell division protein FtsZ and identification of a reliable cross-species inhibitor. ACS Chem Biol. 2012 Nov 16; 7(11):1918-28.
Anderson DE, Kim MB, Moore JT, O'Brien TE, Sorto NA, Grove CI, Lackner LL, Ames JB, Shaw JT. PMID: 22958099; PMCID: PMC3514448.
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PubMed Mentions:
35 Fields:
Translation:
HumansCells
-
The Synthesis and Antimicrobial Activity of Heterocyclic Derivatives of Totarol. ACS Med Chem Lett. 2012 Aug 28; 3(10):818-822.
Kim MB, O'Brien TE, Moore JT, Anderson DE, Foss MH, Weibel DL, Ames JB, Shaw JT. PMID: 23119123; PMCID: PMC3483140.
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PubMed Mentions:
4
-
Synthesis of 6,6'-binaphthopyran-2-one natural products: pigmentosin A, talaroderxines A and B. Org Lett. 2012 Sep 07; 14(17):4338-41.
Grove CI, Di Maso MJ, Jaipuri FA, Kim MB, Shaw JT. PMID: 22889083; PMCID: PMC3461326.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
-
Inhibitors of bacterial tubulin target bacterial membranes in vivo. Medchemcomm. 2013 Jan 01; 4(1):112-119.
Foss MH, Eun YJ, Grove CI, Pauw DA, Sorto NA, Rensvold JW, Pagliarini DJ, Shaw JT, Weibel DB. PMID: 23539337; PMCID: PMC3607388.
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PubMed Mentions:
25
-
Characterization of Caulobacter crescentus FtsZ protein using dynamic light scattering. J Biol Chem. 2012 Jul 06; 287(28):23878-86.
Hou S, Wieczorek SA, Kaminski TS, Ziebacz N, Tabaka M, Sorto NA, Foss MH, Shaw JT, Thanbichler M, Weibel DB, Nieznanski K, Holyst R, Garstecki P. PMID: 22573335; PMCID: PMC3390664.
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PubMed Mentions:
13 Fields:
Translation:
Cells
-
Synthesis of a γ-lactam library via formal cycloaddition of imines and substituted succinic anhydrides. ACS Comb Sci. 2012 Mar 12; 14(3):218-23.
Tan DQ, Atherton AL, Smith AJ, Soldi C, Hurley KA, Fettinger JC, Shaw JT. PMID: 22225535; PMCID: PMC3325288.
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PubMed Mentions:
6 Fields:
Translation:
Cells
-
Second-Generation Synthesis of (-)-Viriditoxin. Synthesis (Stuttg). 2012; 2012(3):362-371.
Grove CI, Shaw JT. PMID: 23049144; PMCID: PMC3461596.
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PubMed Mentions:
5
-
Carbon-carbon bond-forming reactions of α-thioaryl carbonyl compounds for the synthesis of complex heterocyclic molecules. J Org Chem. 2012 Jan 06; 77(1):160-72.
Biggs-Houck JE, Davis RL, Wei J, Mercado BQ, Olmstead MM, Tantillo DJ, Shaw JT. PMID: 22023077.
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PubMed Mentions:
2 Fields:
Translation:
Cells
-
N-Benzyl-3-sulfonamidopyrrolidines are a New Class of Bacterial DNA Gyrase Inhibitors. ACS Med Chem Lett. 2011 Apr 14; 2(4):289-292.
Foss MH, Hurley KA, Sorto N, Lackner LL, Thornton KM, Shaw JT, Weibel DB. PMID: 21552338; PMCID: PMC3088120.
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PubMed Mentions:
8
-
Direct displacement of alkoxy groups of vinylogous esters by Grignard reagents. J Org Chem. 2011 May 06; 76(9):3515-8.
Brockway AJ, González-López M, Fettinger JC, Shaw JT. PMID: 21446670; PMCID: PMC3180960.
View in:
PubMed Mentions:
2 Fields:
Translation:
Cells
-
Synthesis of (-)-viriditoxin: a 6,6'-binaphthopyran-2-one that targets the bacterial cell division protein FtsZ. Angew Chem Int Ed Engl. 2011 Apr 11; 50(16):3730-3.
Park YS, Grove CI, González-López M, Urgaonkar S, Fettinger JC, Shaw JT. PMID: 21413107; PMCID: PMC3325170.
View in:
PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
-
Ammonia synthons for the multicomponent assembly of complex gamma-lactams. Proc Natl Acad Sci U S A. 2011 Apr 26; 108(17):6781-6.
Tan DQ, Martin KS, Fettinger JC, Shaw JT. PMID: 21289284; PMCID: PMC3084106.
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PubMed Mentions:
8 Fields:
Translation:
Cells
-
Diastereoselective synthesis of (±)-heliotropamide by a one-pot, four-component reaction. J Org Chem. 2010 Dec 03; 75(23):8333-6.
Younai A, Chin GF, Shaw JT. PMID: 21062051.
View in:
PubMed Mentions:
6 Fields:
Translation:
Cells
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Practical synthesis of PC190723, an inhibitor of the bacterial cell division protein FtsZ. J Org Chem. 2010 Nov 19; 75(22):7946-9.
Sorto NA, Olmstead MM, Shaw JT. PMID: 21033691; PMCID: PMC3068231.
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PubMed Mentions:
7 Fields:
Translation:
Cells
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Synthesis of antimicrobial natural products targeting FtsZ: (+)-totarol and related totarane diterpenes. Org Lett. 2010 Aug 06; 12(15):3324-7.
Kim MB, Shaw JT. PMID: 20597470; PMCID: PMC2927847.
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PubMed Mentions:
13 Fields:
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Cells
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Recent advances in multicomponent reactions for diversity-oriented synthesis. Curr Opin Chem Biol. 2010 Jun; 14(3):371-82.
Biggs-Houck JE, Younai A, Shaw JT. PMID: 20392661.
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46 Fields:
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Organic linking. ACS Chem Biol. 2010 Mar 19; 5(3):255-6.
Shaw JT, McIntosh M. PMID: 20297849.
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PubMed Mentions: Fields:
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One-step synthesis of complex nitrogen heterocycles from imines and alkyl-substituted maleic anhydrides. Org Lett. 2009 Sep 03; 11(17):3802-5.
Tang Y, Fettinger JC, Shaw JT. PMID: 19708695.
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PubMed Mentions:
6 Fields:
Translation:
Cells
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Cyclic anhydrides in formal cycloadditions and multicomponent reactions. Chem Rev. 2009 Jan; 109(1):164-89.
González-López M, Shaw JT. PMID: 19140773.
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33 Fields:
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Naturally diverse: highlights in versatile synthetic methods enabling target- and diversity-oriented synthesis. Nat Prod Rep. 2009 Jan; 26(1):11-26.
Shaw JT. PMID: 19374120.
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PubMed Mentions:
10 Fields:
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Cells
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Zinc-catalyzed silylation of terminal alkynes. J Org Chem. 2008 Apr 04; 73(7):2912-5.
Rahaim RJ, Shaw JT. PMID: 18331056.
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PubMed Mentions:
5 Fields:
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Cells
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Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization. Dev Cell. 2008 Feb; 14(2):193-204.
Cassidy-Stone A, Chipuk JE, Ingerman E, Song C, Yoo C, Kuwana T, Kurth MJ, Shaw JT, Hinshaw JE, Green DR, Nunnari J. PMID: 18267088; PMCID: PMC2267902.
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PubMed Mentions:
593 Fields:
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HumansAnimalsCells
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Identification of the molecular target of small molecule inhibitors of HDL receptor SR-BI activity. Biochemistry. 2008 Jan 08; 47(1):460-72.
Nieland TJ, Shaw JT, Jaipuri FA, Duffner JL, Koehler AN, Banakos S, Zannis VI, Kirchhausen T, Krieger M. PMID: 18067275; PMCID: PMC2736594.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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N-Benzyl-3-sulfonamidopyrrolidines as novel inhibitors of cell division in E. coli. Bioorg Med Chem Lett. 2007 Dec 01; 17(23):6651-5.
Mukherjee S, Robinson CA, Howe AG, Mazor T, Wood PA, Urgaonkar S, Hebert AM, Raychaudhuri D, Shaw JT. PMID: 17923406; PMCID: PMC3335298.
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PubMed Mentions:
8 Fields:
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Cells
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Diastereoselective synthesis of gamma-lactams by a one-pot, four-component reaction. Org Lett. 2007 Sep 27; 9(20):4077-80.
Wei J, Shaw JT. PMID: 17760458.
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PubMed Mentions:
15 Fields:
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Cells
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Influence of HDL-cholesterol-elevating drugs on the in vitro activity of the HDL receptor SR-BI. J Lipid Res. 2007 Aug; 48(8):1832-45.
Nieland TJ, Shaw JT, Jaipuri FA, Maliga Z, Duffner JL, Koehler AN, Krieger M. PMID: 17533223.
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PubMed Mentions:
10 Fields:
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HumansCells
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Synthesis of kaempferitrin. J Org Chem. 2007 Jun 08; 72(12):4582-5.
Urgaonkar S, Shaw JT. PMID: 17497804.
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PubMed Mentions:
3 Fields:
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Cells
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Synthesis and stereochemical assignment of brasilibactin A. Org Lett. 2007 Apr 26; 9(9):1679-81.
Mitchell JM, Shaw JT. PMID: 17397172.
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PubMed Mentions:
10 Fields:
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Cells
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Synthesis of diverse lactam carboxamides leading to the discovery of a new transcription-factor inhibitor. Angew Chem Int Ed Engl. 2007; 46(28):5352-5.
Ng PY, Tang Y, Knosp WM, Stadler HS, Shaw JT. PMID: 17568465.
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PubMed Mentions:
25 Fields:
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Cells
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Cycloaddition reactions of imines with 3-thiosuccinic anhydrides: synthesis of the tricyclic core of martinellic acid. Org Lett. 2006 Aug 31; 8(18):3999-4002.
Ng PY, Masse CE, Shaw JT. PMID: 16928058.
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PubMed Mentions:
10 Fields:
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Cells
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Divergent structural complexity from a linear reaction sequence: synthesis of fused and spirobicyclic gamma-lactams from common synthetic precursors. J Comb Chem. 2006 May-Jun; 8(3):293-6.
Masse CE, Ng PY, Fukase Y, Sanchez-Roselló M, Shaw JT. PMID: 16676997.
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PubMed Mentions:
6 Fields:
Translation:
Cells
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A structurally diverse library of polycyclic lactams resulting from systematic placement of proximal functional groups. Angew Chem Int Ed Engl. 2006 Mar 03; 45(11):1722-6.
Mitchell JM, Shaw JT. PMID: 16482504.
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PubMed Mentions:
11 Fields:
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HumansAnimalsCells
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Synthesis of antimicrobial natural products targeting FtsZ: (+/-)-dichamanetin and (+/-)-2' ''-hydroxy-5' '-benzylisouvarinol-B. Org Lett. 2005 Dec 08; 7(25):5609-12.
Urgaonkar S, La Pierre HS, Meir I, Lund H, RayChaudhuri D, Shaw JT. PMID: 16321003; PMCID: PMC2588422.
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37 Fields:
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Stereoselective C-glycosylation reactions of ribose derivatives: electronic effects of five-membered ring oxocarbenium ions. J Am Chem Soc. 2005 Aug 10; 127(31):10879-84.
Larsen CH, Ridgway BH, Shaw JT, Smith DM, Woerpel KA. PMID: 16076193.
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PubMed Mentions:
41 Fields:
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Cells
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A new copper acetate-bis(oxazoline)-catalyzed, enantioselective Henry reaction. J Am Chem Soc. 2003 Oct 22; 125(42):12692-3.
Evans DA, Seidel D, Rueping M, Lam HW, Shaw JT, Downey CW. PMID: 14558801.
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PubMed Mentions:
22 Fields:
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Cells
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Diastereoselective nucleophilic substitution reactions of oxasilacyclopentane acetals: application of the "inside attack" model for reactions of five-membered ring oxocarbenium ions. J Org Chem. 2002 Apr 05; 67(7):2056-64.
Bear TJ, Shaw JT, Woerpel KA. PMID: 11925209.
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PubMed Mentions:
4 Fields:
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Cells
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Magnesium halide-catalyzed anti-aldol reactions of chiral N-acylthiazolidinethiones. Org Lett. 2002 Apr 04; 4(7):1127-30.
Evans DA, Downey CW, Shaw JT, Tedrow JS. PMID: 11922799.
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PubMed Mentions:
15 Fields:
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Cells
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Diastereoselective magnesium halide-catalyzed anti-aldol reactions of chiral N-acyloxazolidinones. J Am Chem Soc. 2002 Jan 23; 124(3):392-3.
Evans DA, Tedrow JS, Shaw JT, Downey CW. PMID: 11792206.
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PubMed Mentions:
22 Fields:
Translation:
Cells