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Larry D Cowgill, PhD; DVM

Title(s)Professor, School of Veterinary Medicine
SchoolUniversity of California, Davis
Phone530-752-6543
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Segev G, Stafford C, Kirby J, Cowgill LD. Sequential changes in urine production, glomerular filtration rate, and electrolyte excretion after mannitol administration. J Vet Intern Med. 2019 May; 33(3):1362-1367. PMID: 30927388.
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    2. Foster JD, Drobatz KJ, Cowgill LD. Associations between dialysate sodium concentration and plasma sodium concentration of dogs receiving intermittent hemodialysis treatments. Am J Vet Res. 2018 Apr; 79(4):450-454. PMID: 29583052.
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    3. Takada K, Palm CA, Epstein SE, Cowgill LD. Assessment of Canine Pancreas-Specific Lipase and Outcomes in Dogs with Hemodialysis-Dependent Acute Kidney Injury. J Vet Intern Med. 2018 Mar; 32(2):722-726. PMID: 29469974.
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    4. Segev G, Cowgill LD. Treatment of acute kidney injury associated with cyclosporine overdose in a dog using hemodialysis and charcoal hemoperfusion. J Vet Emerg Crit Care (San Antonio). 2018 Mar; 28(2):163-167. PMID: 29419935.
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    5. Orvalho JS, Cowgill LD. Cardiorenal Syndrome: Diagnosis and Management. Vet Clin North Am Small Anim Pract. 2017 Sep; 47(5):1083-1102. PMID: 28669432.
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    6. Fiocchi EH, Cowgill LD, Brown DC, Markovich JE, Tucker S, Labato MA, Callan MB. The Use of Darbepoetin to Stimulate Erythropoiesis in the Treatment of Anemia of Chronic Kidney Disease in Dogs. J Vet Intern Med. 2017 Mar; 31(2):476-485. PMID: 28256075.
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    7. Cowgill LD, Polzin DJ, Elliott J, Nabity MB, Segev G, Grauer GF, Brown S, Langston C, van Dongen AM. Is Progressive Chronic Kidney Disease a Slow Acute Kidney Injury? Vet Clin North Am Small Anim Pract. 2016 Nov; 46(6):995-1013. PMID: 27593574.
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    8. Polzin DJ, Cowgill LD. Preface. Vet Clin North Am Small Anim Pract. 2016 Nov; 46(6):xiii-xv. PMID: 27593578.
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    9. Segev G, Langston C, Takada K, Kass PH, Cowgill LD. Validation of a Clinical Scoring System for Outcome Prediction in Dogs with Acute Kidney Injury Managed by Hemodialysis. J Vet Intern Med. 2016 May; 30(3):803-7. PMID: 26995335.
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    10. Palm CA, Segev G, Cowgill LD, LeRoy BE, Kowalkowski KL, Kanakubo K, Westropp JL. Urinary Neutrophil Gelatinase-associated Lipocalin as a Marker for Identification of Acute Kidney Injury and Recovery in Dogs with Gentamicin-induced Nephrotoxicity. J Vet Intern Med. 2016 Jan-Feb; 30(1):200-5. PMID: 26725776.
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    11. Hulsebosch SE, Palm CA, Segev G, Cowgill LD, Kass PH, Marks SL. Evaluation of Canine Pancreas-Specific Lipase Activity, Lipase Activity, and Trypsin-Like Immunoreactivity in an Experimental Model of Acute Kidney Injury in Dogs. J Vet Intern Med. 2016 Jan-Feb; 30(1):192-9. PMID: 26678019.
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    12. Pouchelon JL, Atkins CE, Bussadori C, Oyama MA, Vaden SL, Bonagura JD, Chetboul V, Cowgill LD, Elliot J, Francey T, Grauer GF, Fuentes VL, Moise NS, Polzin DJ, Van Dongen AM, Van Israël N. Cardiovascular-renal axis disorders in the domestic dog and cat: a veterinary consensus statement. J Small Anim Pract. 2015 Sep; 56(9):537-52. PMID: 26331869.
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    13. Cianciolo RE, Mohr FC, Aresu L, Brown CA, James C, Jansen JH, Spangler WL, van der Lugt JJ, Kass PH, Brovida C, Cowgill LD, Heiene R, Polzin DJ, Syme H, Vaden SL, van Dongen AM, Lees GE. World Small Animal Veterinary Association Renal Pathology Initiative: Classification of Glomerular Diseases in Dogs. Vet Pathol. 2016 Jan; 53(1):113-35. PMID: 25957358.
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    14. Brown N, Segev G, Francey T, Kass P, Cowgill LD. Glomerular filtration rate, urine production, and fractional clearance of electrolytes in acute kidney injury in dogs and their association with survival. J Vet Intern Med. 2015 Jan; 29(1):28-34. PMID: 25594609.
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    15. Hoareau GL, Epstein SE, Palm C, Ybarra W, Jandrey KE, Cowgill LD. Resolution of anuric acute kidney injury in a dog with multiple organ dysfunction syndrome. J Vet Emerg Crit Care (San Antonio). 2014 Nov-Dec; 24(6):724-30. PMID: 25377656.
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    16. Depner TA, Cowgill LD. Can oral therapy reduce uremic toxins? Clin J Am Soc Nephrol. 2014 Sep 05; 9(9):1513-5. PMID: 25147156.
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    17. Cowgill LD, Polzin DJ. Vision of the WSAVA renal standardization project. J Vet Intern Med. 2013 Nov-Dec; 27 Suppl 1:S5-9. PMID: 24635380.
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    18. Polzin DJ, Cowgill LD. Development of clinical guidelines for management of glomerular disease in dogs. J Vet Intern Med. 2013 Nov-Dec; 27 Suppl 1:S2-4. PMID: 24635377.
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    19. Segev G, Cowgill LD, Heiene R, Labato MA, Polzin DJ. Consensus recommendations for immunosuppressive treatment of dogs with glomerular disease based on established pathology. J Vet Intern Med. 2013 Nov-Dec; 27 Suppl 1:S44-54. PMID: 24635379.
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    20. Goldstein RE, Brovida C, Fernández-Del Palacio MJ, Littman MP, Polzin DJ, Zatelli A, Cowgill LD. Consensus recommendations for treatment for dogs with serology positive glomerular disease. J Vet Intern Med. 2013 Nov-Dec; 27 Suppl 1:S60-6. PMID: 24635382.
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    21. Segev G, Palm C, LeRoy B, Cowgill LD, Westropp JL. Evaluation of neutrophil gelatinase-associated lipocalin as a marker of kidney injury in dogs. J Vet Intern Med. 2013 Nov-Dec; 27(6):1362-7. PMID: 24020513.
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    22. Segev G, Nivy R, Kass PH, Cowgill LD. A retrospective study of acute kidney injury in cats and development of a novel clinical scoring system for predicting outcome for cats managed by hemodialysis. J Vet Intern Med. 2013 Jul-Aug; 27(4):830-9. PMID: 23679089.
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    23. Cowgill LD, Guillaumin J. Extracorporeal renal replacement therapy and blood purification in critical care. J Vet Emerg Crit Care (San Antonio). 2013 Mar-Apr; 23(2):194-204. PMID: 23517350.
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    24. Larry D. Cowgill, Cathy E. Langston. History of Hemodialysis in Dogs and Other Companion Animals. 2012 Oct 1; 901-913.
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    25. Segev G, Cowgill LD, Jessen S, Berkowitz A, Mohr CF, Aroch I. Renal amyloidosis in dogs: a retrospective study of 91 cases with comparison of the disease between Shar-Pei and non-Shar-Pei dogs. J Vet Intern Med. 2012 Mar-Apr; 26(2):259-68. PMID: 22268374.
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    26. Larry D. Cowgill, Thierry Francey. Chapter 29 Hemodialysis and Extracorporeal Blood Purification. 2012 Jan 1; 680-713.
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    27. Cowgill LD. Urea kinetics and intermittent dialysis prescription in small animals. Vet Clin North Am Small Anim Pract. 2011 Jan; 41(1):193-225. PMID: 21251518.
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    28. Heiene R, Eliassen KA, Risøen U, Neal LA, Cowgill LD. Glomerular filtration rate in dogs as estimated via plasma clearance of inulin and iohexol and use of limited-sample methods. Am J Vet Res. 2010 Sep; 71(9):1100-7. PMID: 20807152.
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    29. Boscan P, Pypendop BH, Siao KT, Francey T, Dowers K, Cowgill L, Ilkiw JE. Fluid balance, glomerular filtration rate, and urine output in dogs anesthetized for an orthopedic surgical procedure. Am J Vet Res. 2010 May; 71(5):501-7. PMID: 20433374.
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    30. Segev G, Fascetti AJ, Weeth LP, Cowgill LD. Correction of hyperkalemia in dogs with chronic kidney disease consuming commercial renal therapeutic diets by a potassium-reduced home-prepared diet. J Vet Intern Med. 2010 May-Jun; 24(3):546-50. PMID: 20337915.
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    31. Segev G, Bandt C, Francey T, Cowgill LD. Aluminum toxicity following administration of aluminum-based phosphate binders in 2 dogs with renal failure. J Vet Intern Med. 2008 Nov-Dec; 22(6):1432-5. PMID: 19000253.
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    32. Segev G, Kass PH, Francey T, Cowgill LD. A novel clinical scoring system for outcome prediction in dogs with acute kidney injury managed by hemodialysis. J Vet Intern Med. 2008 Mar-Apr; 22(2):301-8. PMID: 18371024.
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    33. Brown S, Atkins C, Bagley R, Carr A, Cowgill L, Davidson M, Egner B, Elliott J, Henik R, Labato M, Littman M, Polzin D, Ross L, Snyder P, Stepien R. Guidelines for the identification, evaluation, and management of systemic hypertension in dogs and cats. J Vet Intern Med. 2007 May-Jun; 21(3):542-58. PMID: 17552466.
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    34. McClellan JM, Goldstein RE, Erb HN, Dykes NL, Cowgill LD. Effects of administration of fluids and diuretics on glomerular filtration rate, renal blood flow, and urine output in healthy awake cats. Am J Vet Res. 2006 Apr; 67(4):715-22. PMID: 16579767.
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    35. Larry D. Cowgill, Thierry Francey. Chapter 29 Hemodialysis. 2006 Jan 1; (J Clin Invest381959):650-677.
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    36. Kyles AE, Hardie EM, Wooden BG, Adin CA, Stone EA, Gregory CR, Mathews KG, Cowgill LD, Vaden S, Nyland TG, Ling GV. Management and outcome of cats with ureteral calculi: 153 cases (1984-2002). J Am Vet Med Assoc. 2005 Mar 15; 226(6):937-44. PMID: 15786997.
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    37. Kyles AE, Hardie EM, Wooden BG, Adin CA, Stone EA, Gregory CR, Mathews KG, Cowgill LD, Vaden S, Nyland TG, Ling GV. Clinical, clinicopathologic, radiographic, and ultrasonographic abnormalities in cats with ureteral calculi: 163 cases (1984-2002). J Am Vet Med Assoc. 2005 Mar 15; 226(6):932-6. PMID: 15786996.
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    38. Fischer JR, Pantaleo V, Francey T, Cowgill LD. Veterinary hemodialysis: advances in management and technology. Vet Clin North Am Small Anim Pract. 2004 Jul; 34(4):935-67, vi-vii. PMID: 15223210.
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    39. Fielding CL, Magdesian KG, Elliott DA, Cowgill LD, Carlson GP. Use of multifrequency bioelectrical impedance analysis for estimation of total body water and extracellular and intracellular fluid volumes in horses. Am J Vet Res. 2004 Mar; 65(3):320-6. PMID: 15027680.
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    40. Adin CA, Herrgesell EJ, Nyland TG, Hughes JM, Gregory CR, Kyles AE, Cowgill LD, Ling GV. Antegrade pyelography for suspected ureteral obstruction in cats: 11 cases (1995-2001). J Am Vet Med Assoc. 2003 Jun 01; 222(11):1576-81. PMID: 12784966.
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    41. Pressler BM, Vaden SL, Lane IF, Cowgill LD, Dye JA. Candida spp. urinary tract infections in 13 dogs and seven cats: predisposing factors, treatment, and outcome. J Am Anim Hosp Assoc. 2003 May-Jun; 39(3):263-70. PMID: 12755200.
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    42. Cowgill LD. Advanced therapeutic approaches for the management of uraemia--'the met and unmet needs'. J Feline Med Surg. 2003 Feb; 5(1):57-67. PMID: 12613495.
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    43. Adin CA, Gregory CR, Adin DB, Cowgill LD, Kyles AE. Evaluation of three peripheral arteriovenous fistulas for hemodialysis access in dogs. Vet Surg. 2002 Sep-Oct; 31(5):405-11. PMID: 12209410.
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    44. Winchester JF, Ronco C, Brady JA, Cowgill LD, Salsberg J, Yousha E, Choquette M, Albright R, Clemmer J, Davankov V, Tsyurupa M, Pavlova L, Pavlov M, Cohen G, Hörl W, Gotch F, Levin NW. The next step from high-flux dialysis: application of sorbent technology. Blood Purif. 2002; 20(1):81-6. PMID: 11803163.
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    45. Winchester FJ, Ronco C, Salsberg J, Yousha E, Brady JA, Cowgill LD, Choquette M, Albright R, Clemmer J, Davankov V, Tsyurupa M, Pavlova L, Pavlov M, Cohen G, Hörl W, Gotch F, Levin NW. Sorbent augmented dialysis systems. Contrib Nephrol. 2002; (137):170-80. PMID: 12101951.
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    46. Adin CA, Gregory CR, Kyles AE, Cowgill L. Diagnostic predictors of complications and survival after renal transplantation in cats. Vet Surg. 2001 Nov-Dec; 30(6):515-21. PMID: 11704946.
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    47. Heiene R, Vulliet PR, Williams RL, Cowgill LD. Use of capillary electrophoresis to quantitate carbamylated hemoglobin concentrations in dogs with renal failure. Am J Vet Res. 2001 Aug; 62(8):1302-6. PMID: 11497455.
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    48. Winchester JF, Ronco C, Brady JA, Golds E, Clemmer J, Cowgill LD, Muller TE, Levin NW. Sorbent augmented dialysis: minor addition or major advance in therapy? Blood Purif. 2001; 19(2):255-9. PMID: 11150820.
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    49. Grauer GF, Greco DS, Getzy DM, Cowgill LD, Vaden SL, Chew DJ, Polzin DJ, Barsanti JA. Effects of enalapril versus placebo as a treatment for canine idiopathic glomerulonephritis. J Vet Intern Med. 2000 Sep-Oct; 14(5):526-33. PMID: 11012117.
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    50. Elliott DA, Marks SL, Cowgill LD, Kass PH, Rogers QR. Effect of hemodialysis on plasma amino acid concentrations in healthy dogs. Am J Vet Res. 2000 Aug; 61(8):869-73. PMID: 10951974.
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    51. Adin CA, Cowgill LD. Treatment and outcome of dogs with leptospirosis: 36 cases (1990-1998). J Am Vet Med Assoc. 2000 Feb 01; 216(3):371-5. PMID: 10668536.
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    52. Kass PH, Peterson ME, Levy J, James K, Becker DV, Cowgill LD. Evaluation of environmental, nutritional, and host factors in cats with hyperthyroidism. J Vet Intern Med. 1999 Jul-Aug; 13(4):323-9. PMID: 10449223.
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    53. Goldstein RE, Marks SL, Cowgill LD, Kass PH, Rogers QR. Plasma amino acid profiles in cats with naturally acquired chronic renal failure. Am J Vet Res. 1999 Jan; 60(1):109-13. PMID: 9918157.
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    54. Goldstein RE, Marks SL, Kass PH, Cowgill LD. Gastrin concentrations in plasma of cats with chronic renal failure. J Am Vet Med Assoc. 1998 Sep 15; 213(6):826-8. PMID: 9743721.
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    55. Barthez PY, Hornof WJ, Cowgill LD, Neal LA, Mickel P. Comparison between the scintigraphic uptake and plasma clearance of 99mTc-diethylenetriaminepentacetic acid (DTPA) for the evaluation of the glomerular filtration rate in dogs. Vet Radiol Ultrasound. 1998 Sep-Oct; 39(5):470-4. PMID: 9771601.
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    56. Cowgill LD, James KM, Levy JK, Browne JK, Miller A, Lobingier RT, Egrie JC. Use of recombinant human erythropoietin for management of anemia in dogs and cats with renal failure. J Am Vet Med Assoc. 1998 Feb 15; 212(4):521-8. PMID: 9491159.
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    57. Vaden SL, Gookin J, Trogdon M, Langston CE, Levine J, Cowgill LD. Use of carbamylated hemoglobin concentration to differentiate acute from chronic renal failure in dogs. Am J Vet Res. 1997 Nov; 58(11):1193-6. PMID: 9361876.
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    58. Langston CE, Cowgill LD, Spano JA. Applications and outcome of hemodialysis in cats: a review of 29 cases. J Vet Intern Med. 1997 Nov-Dec; 11(6):348-55. PMID: 9470160.
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    59. Kallet AJ, Cowgill LD, Kass PH. Comparison of blood pressure measurements obtained in dogs by use of indirect oscillometry in a veterinary clinic versus at home. J Am Vet Med Assoc. 1997 Mar 01; 210(5):651-4. PMID: 9054993.
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    60. Ortega TM, Feldman EC, Nelson RW, Willits N, Cowgill LD. Systemic arterial blood pressure and urine protein/creatinine ratio in dogs with hyperadrenocorticism. J Am Vet Med Assoc. 1996 Nov 15; 209(10):1724-9. PMID: 8921029.
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    61. Cowgill LD, Langston CE. Role of hemodialysis in the management of dogs and cats with renal failure. Vet Clin North Am Small Anim Pract. 1996 Nov; 26(6):1347-78. PMID: 8911023.
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    62. Cook AK, Cowgill LD. Clinical and pathological features of protein-losing glomerular disease in the dog: a review of 137 cases (1985-1992). J Am Anim Hosp Assoc. 1996 Jul-Aug; 32(4):313-22. PMID: 8784722.
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    63. Pascoe PJ, Ilkiw JE, Kass PH, Cowgill LD. Case-control study of the association between intraoperative administration of nafcillin and acute postoperative development of azotemia. J Am Vet Med Assoc. 1996 Apr 01; 208(7):1043-7. PMID: 8621315.
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    64. Levy JK, James KM, Cowgill LD, Guilford WG, Davidson AP. Decreased urinary catecholamines in a cat with dysautonomia. J Am Vet Med Assoc. 1994 Sep 15; 205(6):842-4. PMID: 7829377.
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    65. Pascoe PJ, Ilkiw JE, Cowgill LD. Concerned about renal failure after anesthesia/surgery. J Am Vet Med Assoc. 1994 Jun 01; 204(11):1734. PMID: 8063588.
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    66. Vivrette S, Cowgill LD, Pascoe J, Suter C, Becker T. Hemodialysis for treatment of oxytetracycline-induced acute renal failure in a neonatal foal. J Am Vet Med Assoc. 1993 Jul 01; 203(1):105-7. PMID: 8407440.
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    67. Cardinet GH, Gourley IM, BonDurant RH, Cowgill LD, Stannard AA, McCapes RH, Smith BP, Rhode EA. Changing dimensions of veterinary medical education in pursuit of diversity and flexibility in service to society. J Am Vet Med Assoc. 1992 Nov 15; 201(10):1530-9. PMID: 1289329.
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    68. Cowgill LD. Pathophysiology and management of anemia in chronic progressive renal failure. Semin Vet Med Surg (Small Anim). 1992 Aug; 7(3):175-82. PMID: 1410849.
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    69. Turrel JM, Lowenstine LJ, Cowgill LD. Response to radiation therapy of recurrent lymphangioma in a dog. J Am Vet Med Assoc. 1988 Dec 01; 193(11):1432-4. PMID: 3209459.
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    70. Gregory CR, Gourley IM, Cain GR, Broaddus TW, Cowgill LD, Willits NH, Patz JD, Ishizaki G. Effects of combination cyclosporine/mizoribine immunosuppression on canine renal allograft recipients. Transplantation. 1988 May; 45(5):856-9. PMID: 3285530.
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    71. Gregory CR, Gourley IM, Haskins SC, Cain GR, Ishizaki G, Cowgill LD, Willits NH, Patz JD. Effects of mizoribine on canine renal allograft recipients. Am J Vet Res. 1988 Mar; 49(3):305-11. PMID: 3282456.
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    72. Hornof WJ, Cowgill LD, Conrad GR, Fisher P. Semiautomated renal region-of-interest selection method: validation in a dog model. Am J Physiol Imaging. 1988; 3(3):133-8. PMID: 3056464.
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    73. Bogusky RT, Garwood M, Matson GB, Acosta G, Cowgill LD, Schleich T. Localization of phosphorus metabolites and sodium ions in the rat kidney. Magn Reson Med. 1986 Apr; 3(2):251-61. PMID: 3713489.
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    74. Cowgill LD, Spangler WL. Renal insufficiency in geriatric dogs. Vet Clin North Am Small Anim Pract. 1981 Nov; 11(4):727-48. PMID: 7039073.
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    75. Ling GV, Ackerman N, Lowenstine LJ, Cowgill LD. Percutaneous nephropyelocentesis and nephropyelostomy in the dog: a description of the technique. Am J Vet Res. 1979 Nov; 40(11):1605-12. PMID: 525880.
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    76. Cowgill LD, Goldfarb S, Lau K, Slatopolsky E, Agus ZS. Evidence for an intrinsic renal tubular defect in mice with genetic hypophosphatemic rickets. J Clin Invest. 1979 Jun; 63(6):1203-10. PMID: 221535.
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    77. Merritt AM, Burrows CF, Cowgill L, Streett W. Fecal fat and trypsin in dogs fed a meat-base or cereal-base diet. J Am Vet Med Assoc. 1979 Jan 01; 174(1):59-61. PMID: 457571.
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