Stephen C Kowalczykowski

Title(s)Professor, Microbiology and Molecular Genetics
SchoolCollege of Biological Sciences
Address310 Briggs Hall
CA 95616
Phone530-752-5938
vCardDownload vCard
    Other Positions
    Title(s)Professional Researcher, Microbiology and Molecular Genetics


    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Trans-complementation by the RecB nuclease domain of RecBCD enzyme reveals new insight into RecA loading upon χ recognition. Nucleic Acids Res. 2024 Mar 21; 52(5):2578-2589. Pavankumar TL, Wong CJ, Wong YK, Spies M, Kowalczykowski SC. PMID: 38261972; PMCID: PMC10954480.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    2. Specific anchoring of large topologically closed DNA for single-molecule protein:DNA interactions. Biophys Rep (N Y). 2024 Mar 13; 4(1):100144. Gilhooly NS, Kowalczykowski SC. PMID: 38390466; PMCID: PMC10881311.
      View in: PubMed   Mentions:
    3. Assembly mechanism and cryoEM structure of RecA recombination nucleofilaments from Streptococcus pneumoniae. Nucleic Acids Res. 2023 04 11; 51(6):2800-2817. Hertzog M, Perry TN, Dupaigne P, Serres S, Morales V, Soulet AL, Bell JC, Margeat E, Kowalczykowski SC, Le Cam E, Fronzes R, Polard P. PMID: 36806960; PMCID: PMC10085707.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    4. BRCA2 chaperones RAD51 to single molecules of RPA-coated ssDNA. Proc Natl Acad Sci U S A. 2023 04 04; 120(14):e2221971120. Bell JC, Dombrowski CC, Plank JL, Jensen RB, Kowalczykowski SC. PMID: 36976771; PMCID: PMC10083600.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    5. Direct visualization of translesion DNA synthesis polymerase IV at the replisome. Proc Natl Acad Sci U S A. 2022 09 27; 119(39):e2208390119. Tuan PM, Gilhooly NS, Marians KJ, Kowalczykowski SC. PMID: 36122225; PMCID: PMC9522359.
      View in: PubMed   Mentions: 4     Fields:    
    6. Charles M. Radding: A love of science and art. Proc Natl Acad Sci U S A. 2021 02 09; 118(6). West SC, Kowalczykowski SC. PMID: 33495365; PMCID: PMC8017706.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. Role of the Srs2-Rad51 Interaction Domain in Crossover Control in Saccharomyces cerevisiae. Genetics. 2019 08; 212(4):1133-1145. Jenkins SS, Gore S, Guo X, Liu J, Ede C, Veaute X, Jinks-Robertson S, Kowalczykowski SC, Heyer WD. PMID: 31142613; PMCID: PMC6707447.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    8. Independent and Stochastic Action of DNA Polymerases in the Replisome. Cell. 2017 Jun 15; 169(7):1201-1213.e17. Graham JE, Marians KJ, Kowalczykowski SC. PMID: 28622507; PMCID: PMC5548433.
      View in: PubMed   Mentions: 80     Fields:    Translation:Cells
    9. PHF11 promotes DSB resection, ATR signaling, and HR. Genes Dev. 2017 01 01; 31(1):46-58. Gong Y, Handa N, Kowalczykowski SC, de Lange T. PMID: 28115467; PMCID: PMC5287112.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    10. Direct Fluorescent Imaging of Translocation and Unwinding by Individual DNA Helicases. Methods Enzymol. 2016; 581:1-32. Pavankumar TL, Exell JC, Kowalczykowski SC. PMID: 27793277; PMCID: PMC5854184.
      View in: PubMed   Mentions: 2     Fields:    
    11. RecA: Regulation and Mechanism of a Molecular Search Engine: (Trends in Biochemical Sciences, June 2016, Vol. 41, No. 6, 491--507). Trends Biochem Sci. 2016 07; 41(7):646. Bell JC, Kowalczykowski SC. PMID: 27283513.
      View in: PubMed   Mentions: 3     Fields:    
    12. RecA: Regulation and Mechanism of a Molecular Search Engine. Trends Biochem Sci. 2016 06; 41(6):491-507. Bell JC, Kowalczykowski SC. PMID: 27156117; PMCID: PMC4892382.
      View in: PubMed   Mentions: 105     Fields:    Translation:HumansCells
    13. Mechanics and Single-Molecule Interrogation of DNA Recombination. Annu Rev Biochem. 2016 Jun 02; 85:193-226. Bell JC, Kowalczykowski SC. PMID: 27088880.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    14. BRCA2 regulates DMC1-mediated recombination through the BRC repeats. Proc Natl Acad Sci U S A. 2016 Mar 29; 113(13):3515-20. Martinez JS, von Nicolai C, Kim T, Ehlén Å, Mazin AV, Kowalczykowski SC, Carreira A. PMID: 26976601; PMCID: PMC4822569.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    15. Single-molecule visualization of RecQ helicase reveals DNA melting, nucleation, and assembly are required for processive DNA unwinding. Proc Natl Acad Sci U S A. 2015 Dec 15; 112(50):E6852-61. Rad B, Forget AL, Baskin RJ, Kowalczykowski SC. PMID: 26540728; PMCID: PMC4687592.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    16. An Overview of the Molecular Mechanisms of Recombinational DNA Repair. Cold Spring Harb Perspect Biol. 2015 Nov 02; 7(11). Kowalczykowski SC. PMID: 26525148; PMCID: PMC4632670.
      View in: PubMed   Mentions: 249     Fields:    Translation:HumansAnimalsCells
    17. Imaging and energetics of single SSB-ssDNA molecules reveal intramolecular condensation and insight into RecOR function. Elife. 2015 Sep 18; 4:e08646. Bell JC, Liu B, Kowalczykowski SC. PMID: 26381353; PMCID: PMC4652220.
      View in: PubMed   Mentions: 40     Fields:    Translation:Cells
    18. A Dominant Mutation in Human RAD51 Reveals Its Function in DNA Interstrand Crosslink Repair Independent of Homologous Recombination. Mol Cell. 2015 Aug 06; 59(3):478-90. Wang AT, Kim T, Wagner JE, Conti BA, Lach FP, Huang AL, Molina H, Sanborn EM, Zierhut H, Cornes BK, Abhyankar A, Sougnez C, Gabriel SB, Auerbach AD, Kowalczykowski SC, Smogorzewska A. PMID: 26253028; PMCID: PMC4529964.
      View in: PubMed   Mentions: 158     Fields:    Translation:HumansCells
    19. MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex. Nat Commun. 2015 Jul 28; 6:7744. Lee KY, Im JS, Shibata E, Park J, Handa N, Kowalczykowski SC, Dutta A. PMID: 26215093; PMCID: PMC4525285.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    20. Sae2 promotes DNA damage resistance by removing the Mre11-Rad50-Xrs2 complex from DNA and attenuating Rad53 signaling. Proc Natl Acad Sci U S A. 2015 Apr 14; 112(15):E1880-7. Chen H, Donnianni RA, Handa N, Deng SK, Oh J, Timashev LA, Kowalczykowski SC, Symington LS. PMID: 25831494; PMCID: PMC4403154.
      View in: PubMed   Mentions: 37     Fields:    Translation:Cells
    21. Top3-Rmi1 dissolve Rad51-mediated D loops by a topoisomerase-based mechanism. Mol Cell. 2015 Feb 19; 57(4):595-606. Fasching CL, Cejka P, Kowalczykowski SC, Heyer WD. PMID: 25699708; PMCID: PMC4338411.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimals
    22. RecQ helicase and RecJ nuclease provide complementary functions to resect DNA for homologous recombination. Proc Natl Acad Sci U S A. 2014 Dec 02; 111(48):E5133-42. Morimatsu K, Kowalczykowski SC. PMID: 25411316; PMCID: PMC4260596.
      View in: PubMed   Mentions: 41     Fields:    Translation:Cells
    23. Structural and mechanistic insight into Holliday-junction dissolution by topoisomerase IIIα and RMI1. Nat Struct Mol Biol. 2014 Mar; 21(3):261-8. Bocquet N, Bizard AH, Abdulrahman W, Larsen NB, Faty M, Cavadini S, Bunker RD, Kowalczykowski SC, Cejka P, Hickson ID, Thomä NH. PMID: 24509834; PMCID: PMC4292918.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCells
    24. DNA unwinding heterogeneity by RecBCD results from static molecules able to equilibrate. Nature. 2013 Aug 22; 500(7463):482-5. Liu B, Baskin RJ, Kowalczykowski SC. PMID: 23851395; PMCID: PMC3779544.
      View in: PubMed   Mentions: 44     Fields:    Translation:Cells
    25. Pif1 family helicases suppress genome instability at G-quadruplex motifs. Nature. 2013 May 23; 497(7450):458-62. Paeschke K, Bochman ML, Garcia PD, Cejka P, Friedman KL, Kowalczykowski SC, Zakian VA. PMID: 23657261; PMCID: PMC3680789.
      View in: PubMed   Mentions: 277     Fields:    Translation:HumansAnimalsCells
    26. Relationship of DNA degradation by Saccharomyces cerevisiae exonuclease 1 and its stimulation by RPA and Mre11-Rad50-Xrs2 to DNA end resection. Proc Natl Acad Sci U S A. 2013 Apr 30; 110(18):E1661-8. Cannavo E, Cejka P, Kowalczykowski SC. PMID: 23589858; PMCID: PMC3645542.
      View in: PubMed   Mentions: 84     Fields:    Translation:Animals
    27. Exploring protein-DNA interactions in 3D using in situ construction, manipulation and visualization of individual DNA dumbbells with optical traps, microfluidics and fluorescence microscopy. Nat Protoc. 2013 Mar; 8(3):525-38. Forget AL, Dombrowski CC, Amitani I, Kowalczykowski SC. PMID: 23411634; PMCID: PMC4329291.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    28. BRCA2 is epistatic to the RAD51 paralogs in response to DNA damage. DNA Repair (Amst). 2013 Apr 01; 12(4):306-11. Jensen RB, Ozes A, Kim T, Estep A, Kowalczykowski SC. PMID: 23384538; PMCID: PMC3602134.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    29. Direct imaging of RecA nucleation and growth on single molecules of SSB-coated ssDNA. Nature. 2012 Nov 08; 491(7423):274-8. Bell JC, Plank JL, Dombrowski CC, Kowalczykowski SC. PMID: 23103864; PMCID: PMC4112059.
      View in: PubMed   Mentions: 96     Fields:    Translation:Cells
    30. RecFOR proteins target RecA protein to a DNA gap with either DNA or RNA at the 5' terminus: implication for repair of stalled replication forks. J Biol Chem. 2012 Oct 12; 287(42):35621-35630. Morimatsu K, Wu Y, Kowalczykowski SC. PMID: 22902627; PMCID: PMC3471720.
      View in: PubMed   Mentions: 44     Fields:    Translation:Cells
    31. Decatenation of DNA by the S. cerevisiae Sgs1-Top3-Rmi1 and RPA complex: a mechanism for disentangling chromosomes. Mol Cell. 2012 Sep 28; 47(6):886-96. Cejka P, Plank JL, Dombrowski CC, Kowalczykowski SC. PMID: 22885009; PMCID: PMC3462259.
      View in: PubMed   Mentions: 65     Fields:    Translation:Cells
    32. Saccharomyces cerevisiae Dmc1 and Rad51 proteins preferentially function with Tid1 and Rad54 proteins, respectively, to promote DNA strand invasion during genetic recombination. J Biol Chem. 2012 Aug 17; 287(34):28727-37. Nimonkar AV, Dombrowski CC, Siino JS, Stasiak AZ, Stasiak A, Kowalczykowski SC. PMID: 22761450; PMCID: PMC3436576.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    33. Polyubiquitinated PCNA recruits the ZRANB3 translocase to maintain genomic integrity after replication stress. Mol Cell. 2012 Aug 10; 47(3):396-409. Ciccia A, Nimonkar AV, Hu Y, Hajdu I, Achar YJ, Izhar L, Petit SA, Adamson B, Yoon JC, Kowalczykowski SC, Livingston DM, Haracska L, Elledge SJ. PMID: 22704558; PMCID: PMC3613862.
      View in: PubMed   Mentions: 177     Fields:    Translation:HumansCells
    34. Molecular determinants responsible for recognition of the single-stranded DNA regulatory sequence, χ, by RecBCD enzyme. Proc Natl Acad Sci U S A. 2012 Jun 05; 109(23):8901-6. Handa N, Yang L, Dillingham MS, Kobayashi I, Wigley DB, Kowalczykowski SC. PMID: 22603794; PMCID: PMC3384139.
      View in: PubMed   Mentions: 29     Fields:    Translation:Cells
    35. Alteration of χ recognition by RecBCD reveals a regulated molecular latch and suggests a channel-bypass mechanism for biological control. Proc Natl Acad Sci U S A. 2012 Jun 05; 109(23):8907-12. Yang L, Handa N, Liu B, Dillingham MS, Wigley DB, Kowalczykowski SC. PMID: 22603793; PMCID: PMC3384165.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    36. Translocation of E. coli RecQ helicase on single-stranded DNA. Biochemistry. 2012 Apr 03; 51(13):2921-9. Rad B, Kowalczykowski SC. PMID: 22409300; PMCID: PMC3330151.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    37. Single-molecule imaging of DNA pairing by RecA reveals a three-dimensional homology search. Nature. 2012 Feb 08; 482(7385):423-7. Forget AL, Kowalczykowski SC. PMID: 22318518; PMCID: PMC3288143.
      View in: PubMed   Mentions: 101     Fields:    Translation:Cells
    38. Efficient coupling of ATP hydrolysis to translocation by RecQ helicase. Proc Natl Acad Sci U S A. 2012 Jan 31; 109(5):1443-8. Rad B, Kowalczykowski SC. PMID: 22307597; PMCID: PMC3277138.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    39. Two classes of BRC repeats in BRCA2 promote RAD51 nucleoprotein filament function by distinct mechanisms. Proc Natl Acad Sci U S A. 2011 Jun 28; 108(26):10448-53. Carreira A, Kowalczykowski SC. PMID: 21670257; PMCID: PMC3127913.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansCells
    40. BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair. Genes Dev. 2011 Feb 15; 25(4):350-62. Nimonkar AV, Genschel J, Kinoshita E, Polaczek P, Campbell JL, Wyman C, Modrich P, Kowalczykowski SC. PMID: 21325134; PMCID: PMC3042158.
      View in: PubMed   Mentions: 419     Fields:    Translation:HumansCells
    41. Rmi1 stimulates decatenation of double Holliday junctions during dissolution by Sgs1-Top3. Nat Struct Mol Biol. 2010 Nov; 17(11):1377-82. Cejka P, Plank JL, Bachrati CZ, Hickson ID, Kowalczykowski SC. PMID: 20935631; PMCID: PMC2988882.
      View in: PubMed   Mentions: 126     Fields:    Translation:AnimalsCells
    42. Purified human BRCA2 stimulates RAD51-mediated recombination. Nature. 2010 Oct 07; 467(7316):678-83. Jensen RB, Carreira A, Kowalczykowski SC. PMID: 20729832; PMCID: PMC2952063.
      View in: PubMed   Mentions: 385     Fields:    Translation:HumansCells
    43. DNA end resection by Dna2-Sgs1-RPA and its stimulation by Top3-Rmi1 and Mre11-Rad50-Xrs2. Nature. 2010 Sep 02; 467(7311):112-6. Cejka P, Cannavo E, Polaczek P, Masuda-Sasa T, Pokharel S, Campbell JL, Kowalczykowski SC. PMID: 20811461; PMCID: PMC3089589.
      View in: PubMed   Mentions: 286     Fields:    Translation:AnimalsCells
    44. Single-molecule imaging brings Rad51 nucleoprotein filaments into focus. Trends Cell Biol. 2010 May; 20(5):269-76. Forget AL, Kowalczykowski SC. PMID: 20299221; PMCID: PMC2862779.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    45. The full-length Saccharomyces cerevisiae Sgs1 protein is a vigorous DNA helicase that preferentially unwinds holliday junctions. J Biol Chem. 2010 Mar 12; 285(11):8290-301. Cejka P, Kowalczykowski SC. PMID: 20086270; PMCID: PMC2832980.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    46. Watching individual proteins acting on single molecules of DNA. Methods Enzymol. 2010; 472:261-91. Amitani I, Liu B, Dombrowski CC, Baskin RJ, Kowalczykowski SC. PMID: 20580968; PMCID: PMC3119597.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    47. An alternative form of replication protein a expressed in normal human tissues supports DNA repair. J Biol Chem. 2010 Feb 12; 285(7):4788-97. Kemp MG, Mason AC, Carreira A, Reardon JT, Haring SJ, Borgstahl GE, Kowalczykowski SC, Sancar A, Wold MS. PMID: 19996105; PMCID: PMC2836084.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    48. Visualizing protein-DNA interactions at the single-molecule level. Curr Opin Chem Biol. 2010 Feb; 14(1):15-22. Hilario J, Kowalczykowski SC. PMID: 19945909; PMCID: PMC2819561.
      View in: PubMed   Mentions: 18     Fields:    
    49. BRCA2: Shining light on the regulation of DNA-binding selectivity by RAD51. Cell Cycle. 2009 Nov 01; 8(21):3445-7. Carreira A, Kowalczykowski SC. PMID: 19838057; PMCID: PMC3050000.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    50. Second-end DNA capture in double-strand break repair: how to catch a DNA by its tail. Cell Cycle. 2009 Jun 15; 8(12):1816-7. Nimonkar AV, Kowalczykowski SC. PMID: 19471119; PMCID: PMC3051008.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    51. Reconstitution of initial steps of dsDNA break repair by the RecF pathway of E. coli. Genes Dev. 2009 May 15; 23(10):1234-45. Handa N, Morimatsu K, Lovett ST, Kowalczykowski SC. PMID: 19451222; PMCID: PMC2685532.
      View in: PubMed   Mentions: 81     Fields:    Translation:Cells
    52. Single molecule analysis of a red fluorescent RecA protein reveals a defect in nucleoprotein filament nucleation that relates to its reduced biological functions. J Biol Chem. 2009 Jul 10; 284(28):18664-73. Handa N, Amitani I, Gumlaw N, Sandler SJ, Kowalczykowski SC. PMID: 19419960; PMCID: PMC2707236.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    53. The BRC repeats of BRCA2 modulate the DNA-binding selectivity of RAD51. Cell. 2009 Mar 20; 136(6):1032-43. Carreira A, Hilario J, Amitani I, Baskin RJ, Shivji MK, Venkitaraman AR, Kowalczykowski SC. PMID: 19303847; PMCID: PMC2669112.
      View in: PubMed   Mentions: 142     Fields:    Translation:HumansCells
    54. An archaeal Rad54 protein remodels DNA and stimulates DNA strand exchange by RadA. Nucleic Acids Res. 2009 May; 37(8):2757-70. Haseltine CA, Kowalczykowski SC. PMID: 19282450; PMCID: PMC2677860.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    55. Rad52 promotes second-end DNA capture in double-stranded break repair to form complement-stabilized joint molecules. Proc Natl Acad Sci U S A. 2009 Mar 03; 106(9):3077-82. Nimonkar AV, Sica RA, Kowalczykowski SC. PMID: 19204284; PMCID: PMC2651264.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    56. Direct imaging of human Rad51 nucleoprotein dynamics on individual DNA molecules. Proc Natl Acad Sci U S A. 2009 Jan 13; 106(2):361-8. Hilario J, Amitani I, Baskin RJ, Kowalczykowski SC. PMID: 19122145; PMCID: PMC2613362.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansCells
    57. RecBCD enzyme and the repair of double-stranded DNA breaks. Microbiol Mol Biol Rev. 2008 Dec; 72(4):642-71, Table of Contents. Dillingham MS, Kowalczykowski SC. PMID: 19052323; PMCID: PMC2593567.
      View in: PubMed   Mentions: 293     Fields:    Translation:Cells
    58. Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair. Proc Natl Acad Sci U S A. 2008 Nov 04; 105(44):16906-11. Nimonkar AV, Ozsoy AZ, Genschel J, Modrich P, Kowalczykowski SC. PMID: 18971343; PMCID: PMC2579351.
      View in: PubMed   Mentions: 177     Fields:    Translation:HumansCells
    59. Fluorescent single-stranded DNA binding protein as a probe for sensitive, real-time assays of helicase activity. Biophys J. 2008 Oct; 95(7):3330-9. Dillingham MS, Tibbles KL, Hunter JL, Bell JC, Kowalczykowski SC, Webb MR. PMID: 18599625; PMCID: PMC2547451.
      View in: PubMed   Mentions: 32     Fields:    Translation:Cells
    60. Structural biology: snapshots of DNA repair. Nature. 2008 May 22; 453(7194):463-6. Kowalczykowski SC. PMID: 18497811.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    61. Rad51 protein controls Rad52-mediated DNA annealing. J Biol Chem. 2008 May 23; 283(21):14883-92. Wu Y, Kantake N, Sugiyama T, Kowalczykowski SC. PMID: 18337252; PMCID: PMC2386943.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    62. RecBCD enzyme switches lead motor subunits in response to chi recognition. Cell. 2007 Nov 16; 131(4):694-705. Spies M, Amitani I, Baskin RJ, Kowalczykowski SC. PMID: 18022364; PMCID: PMC2151923.
      View in: PubMed   Mentions: 77     Fields:    Translation:Cells
    63. Single molecule imaging of Tid1/Rdh54, a Rad54 homolog that translocates on duplex DNA and can disrupt joint molecules. J Biol Chem. 2007 Oct 19; 282(42):30776-84. Nimonkar AV, Amitani I, Baskin RJ, Kowalczykowski SC. PMID: 17704061.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    64. RecA. Curr Biol. 2007 Jun 05; 17(11):R395-7. Galletto R, Kowalczykowski SC. PMID: 17550759.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    65. Rad52-mediated DNA annealing after Rad51-mediated DNA strand exchange promotes second ssDNA capture. EMBO J. 2006 Nov 29; 25(23):5539-48. Sugiyama T, Kantake N, Wu Y, Kowalczykowski SC. PMID: 17093500; PMCID: PMC1679760.
      View in: PubMed   Mentions: 71     Fields:    Translation:Cells
    66. A RecA mutant, RecA(730), suppresses the recombination deficiency of the RecBC(1004)D-chi* interaction in vitro and in vivo. J Mol Biol. 2007 Feb 02; 365(5):1314-25. Handa N, Kowalczykowski SC. PMID: 17141804; PMCID: PMC1847798.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    67. The DNA binding preference of RAD52 and RAD59 proteins: implications for RAD52 and RAD59 protein function in homologous recombination. J Biol Chem. 2006 Dec 29; 281(52):40001-9. Wu Y, Siino JS, Sugiyama T, Kowalczykowski SC. PMID: 17040915.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    68. Direct observation of individual RecA filaments assembling on single DNA molecules. Nature. 2006 Oct 19; 443(7113):875-8. Galletto R, Amitani I, Baskin RJ, Kowalczykowski SC. PMID: 16988658.
      View in: PubMed   Mentions: 133     Fields:    Translation:Cells
    69. Visualization of Rad54, a chromatin remodeling protein, translocating on single DNA molecules. Mol Cell. 2006 Jul 07; 23(1):143-8. Amitani I, Baskin RJ, Kowalczykowski SC. PMID: 16818238.
      View in: PubMed   Mentions: 87     Fields:    Translation:AnimalsCells
    70. Human Rad51 protein displays enhanced homologous pairing of DNA sequences resembling those at genetically unstable loci. Nucleic Acids Res. 2006; 34(10):2847-52. Seitz EM, Kowalczykowski SC. PMID: 16723430; PMCID: PMC1474073.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    71. The AddAB helicase/nuclease forms a stable complex with its cognate chi sequence during translocation. J Biol Chem. 2006 Jul 07; 281(27):18610-7. Chédin F, Handa N, Dillingham MS, Kowalczykowski SC. PMID: 16632468.
      View in: PubMed   Mentions: 28     Fields:    Translation:Cells
    72. DNA annealing mediated by Rad52 and Rad59 proteins. J Biol Chem. 2006 Jun 02; 281(22):15441-9. Wu Y, Sugiyama T, Kowalczykowski SC. PMID: 16565518.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    73. The RecA binding locus of RecBCD is a general domain for recruitment of DNA strand exchange proteins. Mol Cell. 2006 Feb 17; 21(4):573-80. Spies M, Kowalczykowski SC. PMID: 16483938.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansCells
    74. Bipolar DNA translocation contributes to highly processive DNA unwinding by RecBCD enzyme. J Biol Chem. 2005 Nov 04; 280(44):37069-77. Dillingham MS, Webb MR, Kowalczykowski SC. PMID: 16041061.
      View in: PubMed   Mentions: 31     Fields:    Translation:Cells
    75. Translocation by the RecB motor is an absolute requirement for {chi}-recognition and RecA protein loading by RecBCD enzyme. J Biol Chem. 2005 Nov 04; 280(44):37078-87. Spies M, Dillingham MS, Kowalczykowski SC. PMID: 16041060.
      View in: PubMed   Mentions: 22     Fields:    Translation:Cells
    76. Structure of the SWI2/SNF2 chromatin-remodeling domain of eukaryotic Rad54. Nat Struct Mol Biol. 2005 Apr; 12(4):350-6. Thomä NH, Czyzewski BK, Alexeev AA, Mazin AV, Kowalczykowski SC, Pavletich NP. PMID: 15806108.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansAnimalsCells
    77. Direct visualization of RecBCD movement reveals cotranslocation of the RecD motor after chi recognition. Mol Cell. 2005 Mar 04; 17(5):745-50. Handa N, Bianco PR, Baskin RJ, Kowalczykowski SC. PMID: 15749023.
      View in: PubMed   Mentions: 55     Fields:    Translation:Cells
    78. Cancer: catalyst of a catalyst. Nature. 2005 Feb 10; 433(7026):591-2. Kowalczykowski SC. PMID: 15703734.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    79. Crystal structure of RecBCD enzyme reveals a machine for processing DNA breaks. Nature. 2004 Nov 11; 432(7014):187-93. Singleton MR, Dillingham MS, Gaudier M, Kowalczykowski SC, Wigley DB. PMID: 15538360.
      View in: PubMed   Mentions: 215     Fields:    Translation:Cells
    80. Saccharomyces cerevisiae Mer3 helicase stimulates 3'-5' heteroduplex extension by Rad51; implications for crossover control in meiotic recombination. Cell. 2004 Apr 02; 117(1):47-56. Mazina OM, Mazin AV, Nakagawa T, Kolodner RD, Kowalczykowski SC. PMID: 15066281.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    81. A molecular throttle: the recombination hotspot chi controls DNA translocation by the RecBCD helicase. Cell. 2003 Sep 05; 114(5):647-54. Spies M, Bianco PR, Dillingham MS, Handa N, Baskin RJ, Kowalczykowski SC. PMID: 13678587.
      View in: PubMed   Mentions: 86     Fields:    Translation:Cells
    82. RecQ helicase stimulates both DNA catenation and changes in DNA topology by topoisomerase III. J Biol Chem. 2003 Oct 24; 278(43):42668-78. Harmon FG, Brockman JP, Kowalczykowski SC. PMID: 12909639.
      View in: PubMed   Mentions: 44     Fields:    Translation:Cells
    83. RecBCD enzyme is a bipolar DNA helicase. Nature. 2003 Jun 19; 423(6942):893-7. Dillingham MS, Spies M, Kowalczykowski SC. PMID: 12815438.
      View in: PubMed   Mentions: 96     Fields:    Translation:Cells
    84. Biochemical basis of the constitutive coprotease activity of RecA P67W protein. Biochemistry. 2003 May 20; 42(19):5937-44. Mirshad JK, Kowalczykowski SC. PMID: 12741852.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    85. Biochemical characterization of a mutant RecA protein altered in DNA-binding loop 1. Biochemistry. 2003 May 20; 42(19):5945-54. Mirshad JK, Kowalczykowski SC. PMID: 12741853.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    86. The Srs2 helicase prevents recombination by disrupting Rad51 nucleoprotein filaments. Nature. 2003 May 15; 423(6937):309-12. Veaute X, Jeusset J, Soustelle C, Kowalczykowski SC, Le Cam E, Fabre F. PMID: 12748645.
      View in: PubMed   Mentions: 343     Fields:    Translation:AnimalsCells
    87. RecFOR proteins load RecA protein onto gapped DNA to accelerate DNA strand exchange: a universal step of recombinational repair. Mol Cell. 2003 May; 11(5):1337-47. Morimatsu K, Kowalczykowski SC. PMID: 12769856.
      View in: PubMed   Mentions: 214     Fields:    Translation:Cells
    88. The recombination-deficient mutant RPA (rfa1-t11) is displaced slowly from single-stranded DNA by Rad51 protein. J Biol Chem. 2003 Jun 27; 278(26):23410-7. Kantake N, Sugiyama T, Kolodner RD, Kowalczykowski SC. PMID: 12697761.
      View in: PubMed   Mentions: 58     Fields:    Translation:Cells
    89. Rad54 protein possesses chromatin-remodeling activity stimulated by the Rad51-ssDNA nucleoprotein filament. Nat Struct Biol. 2003 Mar; 10(3):182-6. Alexeev A, Mazin A, Kowalczykowski SC. PMID: 12577053.
      View in: PubMed   Mentions: 109     Fields:    Translation:AnimalsCells
    90. A novel function of Rad54 protein. Stabilization of the Rad51 nucleoprotein filament. J Biol Chem. 2003 Apr 18; 278(16):14029-36. Mazin AV, Alexeev AA, Kowalczykowski SC. PMID: 12566442.
      View in: PubMed   Mentions: 89     Fields:    Translation:AnimalsCells
    91. Molecular mimicry connects BRCA2 to Rad51 and recombinational DNA repair. Nat Struct Biol. 2002 Dec; 9(12):897-9. Kowalczykowski SC. PMID: 12447354.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    92. Escherichia coli RecO protein anneals ssDNA complexed with its cognate ssDNA-binding protein: A common step in genetic recombination. Proc Natl Acad Sci U S A. 2002 Nov 26; 99(24):15327-32. Kantake N, Madiraju MV, Sugiyama T, Kowalczykowski SC. PMID: 12438681; PMCID: PMC137716.
      View in: PubMed   Mentions: 70     Fields:    Translation:AnimalsCells
    93. Escherichia coli RecX inhibits RecA recombinase and coprotease activities in vitro and in vivo. J Biol Chem. 2003 Jan 24; 278(4):2278-85. Stohl EA, Brockman JP, Burkle KL, Morimatsu K, Kowalczykowski SC, Seifert HS. PMID: 12427742.
      View in: PubMed   Mentions: 76     Fields:    Translation:Cells
    94. Complex formation by the human Rad51B and Rad51C DNA repair proteins and their activities in vitro. J Biol Chem. 2003 Jan 24; 278(4):2469-78. Lio YC, Mazin AV, Kowalczykowski SC, Chen DJ. PMID: 12427746.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    95. Rad52 protein associates with replication protein A (RPA)-single-stranded DNA to accelerate Rad51-mediated displacement of RPA and presynaptic complex formation. J Biol Chem. 2002 Aug 30; 277(35):31663-72. Sugiyama T, Kowalczykowski SC. PMID: 12077133.
      View in: PubMed   Mentions: 128     Fields:    Translation:AnimalsCells
    96. Rad52 protein has a second stimulatory role in DNA strand exchange that complements replication protein-A function. J Biol Chem. 2002 Jul 19; 277(29):26171-6. New JH, Kowalczykowski SC. PMID: 12004070.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    97. A distinctive single-strand DNA-binding protein from the Archaeon Sulfolobus solfataricus. Mol Microbiol. 2002 Mar; 43(6):1505-15. Haseltine CA, Kowalczykowski SC. PMID: 11971263.
      View in: PubMed   Mentions: 29     Fields:    Translation:Cells
    98. A novel family of regulated helicases/nucleases from Gram-positive bacteria: insights into the initiation of DNA recombination. Mol Microbiol. 2002 Feb; 43(4):823-34. Chédin F, Kowalczykowski SC. PMID: 11929535.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    99. Archaeal RadA protein binds DNA as both helical filaments and octameric rings. J Mol Biol. 2001 Dec 14; 314(5):1077-85. Yang S, Yu X, Seitz EM, Kowalczykowski SC, Egelman EH. PMID: 11743724.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    100. Rad54 protein stimulates heteroduplex DNA formation in the synaptic phase of DNA strand exchange via specific interactions with the presynaptic Rad51 nucleoprotein filament. J Mol Biol. 2001 Apr 13; 307(5):1207-21. Solinger JA, Lutz G, Sugiyama T, Kowalczykowski SC, Heyer WD. PMID: 11292336.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    101. Biochemical characterization of the DNA helicase activity of the escherichia coli RecQ helicase. J Biol Chem. 2001 Jan 05; 276(1):232-43. Harmon FG, Kowalczykowski SC. PMID: 11024023.
      View in: PubMed   Mentions: 63     Fields:    Translation:Cells
    102. Some assembly required. Nat Struct Biol. 2000 Dec; 7(12):1087-9. Kowalczykowski SC. PMID: 11101884.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    103. Rad54 protein is targeted to pairing loci by the Rad51 nucleoprotein filament. Mol Cell. 2000 Sep; 6(3):583-92. Mazin AV, Bornarth CJ, Solinger JA, Heyer WD, Kowalczykowski SC. PMID: 11030338.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansAnimalsCells
    104. The DNA binding and pairing preferences of the archaeal RadA protein demonstrate a universal characteristic of DNA strand exchange proteins. Mol Microbiol. 2000 Aug; 37(3):555-60. Seitz EM, Kowalczykowski SC. PMID: 10931349.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    105. A novel, 11 nucleotide variant of chi, chi*: one of a class of sequences defining the Escherichia coli recombination hotspot chi. J Mol Biol. 2000 Jul 14; 300(3):469-79. Arnold DA, Handa N, Kobayashi I, Kowalczykowski SC. PMID: 10884344.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    106. Translocation step size and mechanism of the RecBC DNA helicase. Nature. 2000 May 18; 405(6784):368-72. Bianco PR, Kowalczykowski SC. PMID: 10830968.
      View in: PubMed   Mentions: 40     Fields:    Translation:Cells
    107. Facilitated loading of RecA protein is essential to recombination by RecBCD enzyme. J Biol Chem. 2000 Apr 21; 275(16):12261-5. Arnold DA, Kowalczykowski SC. PMID: 10766864.
      View in: PubMed   Mentions: 35     Fields:    Translation:Cells
    108. The Bacillus subtilis AddAB helicase/nuclease is regulated by its cognate Chi sequence in vitro. J Mol Biol. 2000 Apr 21; 298(1):7-20. Chédin F, Ehrlich SD, Kowalczykowski SC. PMID: 10756102.
      View in: PubMed   Mentions: 42     Fields:    Translation:Cells
    109. Initiation of genetic recombination and recombination-dependent replication. Trends Biochem Sci. 2000 Apr; 25(4):156-65. Kowalczykowski SC. PMID: 10754547.
      View in: PubMed   Mentions: 267     Fields:    Translation:Cells
    110. Identification of the RecA protein-loading domain of RecBCD enzyme. J Mol Biol. 2000 Mar 31; 297(3):537-42. Churchill JJ, Kowalczykowski SC. PMID: 10731409.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    111. A novel pairing process promoted by Escherichia coli RecA protein: inverse DNA and RNA strand exchange. Genes Dev. 2000 Mar 15; 14(6):740-9. Zaitsev EN, Kowalczykowski SC. PMID: 10733533; PMCID: PMC316457.
      View in: PubMed   Mentions: 52     Fields:    Translation:Cells
    112. Tailed duplex DNA is the preferred substrate for Rad51 protein-mediated homologous pairing. EMBO J. 2000 Mar 01; 19(5):1148-56. Mazin AV, Zaitseva E, Sung P, Kowalczykowski SC. PMID: 10698955; PMCID: PMC305653.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    113. Coupling of DNA helicase function to DNA strand exchange activity. Methods Mol Biol. 2000; 152:75-89. Harmon FG, Kowalczykowski SC. PMID: 10957970.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    114. Enhanced monomer-monomer interactions can suppress the recombination deficiency of the recA142 allele. Mol Microbiol. 1999 Oct; 34(1):1-9. Zaitsev EN, Kowalczykowski SC. PMID: 10540281.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    115. A single mutation, RecB(D1080A,) eliminates RecA protein loading but not Chi recognition by RecBCD enzyme. J Biol Chem. 1999 Sep 17; 274(38):27139-44. Anderson DG, Churchill JJ, Kowalczykowski SC. PMID: 10480929.
      View in: PubMed   Mentions: 36     Fields:    Translation:Cells
    116. A novel property of the RecA nucleoprotein filament: activation of double- stranded DNA for strand exchange in trans. Genes Dev. 1999 Aug 01; 13(15):2005-16. Mazin AV, Kowalczykowski SC. PMID: 10444598; PMCID: PMC316918.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    117. RecQ helicase and topoisomerase III comprise a novel DNA strand passage function: a conserved mechanism for control of DNA recombination. Mol Cell. 1999 May; 3(5):611-20. Harmon FG, DiGate RJ, Kowalczykowski SC. PMID: 10360177.
      View in: PubMed   Mentions: 98     Fields:    Translation:AnimalsCells
    118. The RecBC enzyme loads RecA protein onto ssDNA asymmetrically and independently of chi, resulting in constitutive recombination activation. Genes Dev. 1999 Apr 01; 13(7):901-11. Churchill JJ, Anderson DG, Kowalczykowski SC. PMID: 10197989; PMCID: PMC316600.
      View in: PubMed   Mentions: 68     Fields:    Translation:Cells
    119. The simultaneous binding of two double-stranded DNA molecules by Escherichia coli RecA protein. J Mol Biol. 1999 Mar 19; 287(1):21-31. Zaitsev EN, Kowalczykowski SC. PMID: 10074404.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    120. The DNA binding properties of Saccharomyces cerevisiae Rad51 protein. J Biol Chem. 1999 Jan 29; 274(5):2907-15. Zaitseva EM, Zaitsev EN, Kowalczykowski SC. PMID: 9915828.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    121. Reconstitution of an SOS response pathway: derepression of transcription in response to DNA breaks. Cell. 1998 Dec 23; 95(7):975-9. Anderson DG, Kowalczykowski SC. PMID: 9875851.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    122. Modulation of RecA nucleoprotein function by the mutagenic UmuD'C protein complex. J Biol Chem. 1998 Dec 04; 273(49):32384-7. Rehrauer WM, Bruck I, Woodgate R, Goodman MF, Kowalczykowski SC. PMID: 9829966.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    123. [Preference of RecA-filament to the DNA sequences correlates with genetic code]. Dokl Akad Nauk. 1998 Nov; 363(1):122-5. Ponomarenko MP, Ponomarenko IuV, Titov II, Kolchanov NA, Mazin AV, Kowalczykowski SC. PMID: 9891200.
      View in: PubMed   Mentions:    Fields:    
    124. SSB protein controls RecBCD enzyme nuclease activity during unwinding: a new role for looped intermediates. J Mol Biol. 1998 Sep 18; 282(2):275-85. Anderson DG, Kowalczykowski SC. PMID: 9735287.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    125. Essential monomer-monomer contacts define the minimal length for the N-terminus of RecA protein. Mol Microbiol. 1998 Sep; 29(5):1317-8. Zaitsev EN, Kowalczykowski SC. PMID: 9767598.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    126. Novel homologs of replication protein A in archaea: implications for the evolution of ssDNA-binding proteins. Trends Biochem Sci. 1998 Aug; 23(8):273-7. Chédin F, Seitz EM, Kowalczykowski SC. PMID: 9757822.
      View in: PubMed   Mentions: 30     Fields:    Translation:Cells
    127. The reduced levels of chi recognition exhibited by the RecBC1004D enzyme reflect its recombination defect in vivo. J Biol Chem. 1998 Jun 26; 273(26):16476-86. Arnold DA, Bianco PR, Kowalczykowski SC. PMID: 9632715.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    128. DNA strand exchange proteins: a biochemical and physical comparison. Front Biosci. 1998 Jun 17; 3:D570-603. Bianco PR, Tracy RB, Kowalczykowski SC. PMID: 9632377.
      View in: PubMed   Mentions: 178     Fields:    Translation:AnimalsCells
    129. DNA annealing by RAD52 protein is stimulated by specific interaction with the complex of replication protein A and single-stranded DNA. Proc Natl Acad Sci U S A. 1998 May 26; 95(11):6049-54. Sugiyama T, New JH, Kowalczykowski SC. PMID: 9600915; PMCID: PMC27583.
      View in: PubMed   Mentions: 172     Fields:    Translation:HumansAnimalsCells
    130. RadA protein is an archaeal RecA protein homolog that catalyzes DNA strand exchange. Genes Dev. 1998 May 01; 12(9):1248-53. Seitz EM, Brockman JP, Sandler SJ, Clark AJ, Kowalczykowski SC. PMID: 9573041; PMCID: PMC316774.
      View in: PubMed   Mentions: 84     Fields:    Translation:Cells
    131. RecQ helicase, in concert with RecA and SSB proteins, initiates and disrupts DNA recombination. Genes Dev. 1998 Apr 15; 12(8):1134-44. Harmon FG, Kowalczykowski SC. PMID: 9553043; PMCID: PMC316708.
      View in: PubMed   Mentions: 111     Fields:    Translation:Cells
    132. The function of the secondary DNA-binding site of RecA protein during DNA strand exchange. EMBO J. 1998 Feb 16; 17(4):1161-8. Mazin AV, Kowalczykowski SC. PMID: 9463393; PMCID: PMC1170464.
      View in: PubMed   Mentions: 36     Fields:    Translation:Cells
    133. Rad52 protein stimulates DNA strand exchange by Rad51 and replication protein A. Nature. 1998 Jan 22; 391(6665):407-10. New JH, Sugiyama T, Zaitseva E, Kowalczykowski SC. PMID: 9450760.
      View in: PubMed   Mentions: 260     Fields:    Translation:AnimalsCells
    134. Binding of double-stranded DNA by Escherichia coli RecA protein monitored by a fluorescent dye displacement assay. Nucleic Acids Res. 1998 Jan 15; 26(2):650-4. Zaitsev EN, Kowalczykowski SC. PMID: 9421529; PMCID: PMC147265.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    135. The preference for GT-rich DNA by the yeast Rad51 protein defines a set of universal pairing sequences. Genes Dev. 1997 Dec 15; 11(24):3423-31. Tracy RB, Baumohl JK, Kowalczykowski SC. PMID: 9407034; PMCID: PMC316816.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    136. The recombination hot spot chi is embedded within islands of preferred DNA pairing sequences in the E. coli genome. Cell. 1997 Jul 25; 90(2):205-6. Tracy RB, Chédin F, Kowalczykowski SC. PMID: 9244294.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    137. The translocating RecBCD enzyme stimulates recombination by directing RecA protein onto ssDNA in a chi-regulated manner. Cell. 1997 Jul 11; 90(1):77-86. Anderson DG, Kowalczykowski SC. PMID: 9230304.
      View in: PubMed   Mentions: 144     Fields:    Translation:Cells
    138. The recombination hotspot Chi is recognized by the translocating RecBCD enzyme as the single strand of DNA containing the sequence 5'-GCTGGTGG-3'. Proc Natl Acad Sci U S A. 1997 Jun 24; 94(13):6706-11. Bianco PR, Kowalczykowski SC. PMID: 9192629; PMCID: PMC21222.
      View in: PubMed   Mentions: 35     Fields:    Translation:Cells
    139. A single-stranded DNA-binding protein is needed for efficient presynaptic complex formation by the Saccharomyces cerevisiae Rad51 protein. J Biol Chem. 1997 Mar 21; 272(12):7940-5. Sugiyama T, Zaitseva EM, Kowalczykowski SC. PMID: 9065463.
      View in: PubMed   Mentions: 140     Fields:    Translation:AnimalsCells
    140. The recombination hot spot chi is a regulatory element that switches the polarity of DNA degradation by the RecBCD enzyme. Genes Dev. 1997 Mar 01; 11(5):571-81. Anderson DG, Kowalczykowski SC. PMID: 9119222.
      View in: PubMed   Mentions: 70     Fields:    Translation:Cells
    141. Chi-activated RecBCD enzyme possesses 5'-->3' nucleolytic activity, but RecBC enzyme does not: evidence suggesting that the alteration induced by Chi is not simply ejection of the RecD subunit. Genes Cells. 1997 Feb; 2(2):117-28. Anderson DG, Churchill JJ, Kowalczykowski SC. PMID: 9167969.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    142. The specificity of the secondary DNA binding site of RecA protein defines its role in DNA strand exchange. Proc Natl Acad Sci U S A. 1996 Oct 01; 93(20):10673-8. Mazin AV, Kowalczykowski SC. PMID: 8855238; PMCID: PMC38213.
      View in: PubMed   Mentions: 31     Fields:    Translation:Cells
    143. Interaction of Escherichia coli RecA protein with LexA repressor. I. LexA repressor cleavage is competitive with binding of a secondary DNA molecule. J Biol Chem. 1996 Sep 27; 271(39):23865-73. Rehrauer WM, Lavery PE, Palmer EL, Singh RN, Kowalczykowski SC. PMID: 8798617.
      View in: PubMed   Mentions: 22     Fields:    Translation:Cells
    144. Interaction of Escherichia coli RecA protein with LexA repressor. II. Inhibition of DNA strand exchange by the uncleavable LexA S119A repressor argues that recombination and SOS induction are competitive processes. J Biol Chem. 1996 Sep 27; 271(39):23874-83. Harmon FG, Rehrauer WM, Kowalczykowski SC. PMID: 8798618.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    145. In vitro selection of preferred DNA pairing sequences by the Escherichia coli RecA protein. Genes Dev. 1996 Aug 01; 10(15):1890-903. Tracy RB, Kowalczykowski SC. PMID: 8756347.
      View in: PubMed   Mentions: 24     Fields:    Translation:Cells
    146. The DNA binding site(s) of the Escherichia coli RecA protein. J Biol Chem. 1996 May 17; 271(20):11996-2002. Rehrauer WM, Kowalczykowski SC. PMID: 8662640.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    147. A helicase assay based on the displacement of fluorescent, nucleic acid-binding ligands. Nucleic Acids Res. 1996 Apr 01; 24(7):1179-86. Eggleston AK, Rahim NA, Kowalczykowski SC. PMID: 8614617; PMCID: PMC145774.
      View in: PubMed   Mentions: 29     Fields:    Translation:Cells
    148. Role of the Escherichia coli recombination hotspot, chi, in RecABCD-dependent homologous pairing. J Biol Chem. 1995 Jul 07; 270(27):16360-70. Dixon DA, Kowalczykowski SC. PMID: 7608206.
      View in: PubMed   Mentions: 29     Fields:    Translation:Cells
    149. DNA-strand exchange promoted by RecA protein in the absence of ATP: implications for the mechanism of energy transduction in protein-promoted nucleic acid transactions. Proc Natl Acad Sci U S A. 1995 Apr 11; 92(8):3478-82. Kowalczykowski SC, Krupp RA. PMID: 7724585; PMCID: PMC42190.
      View in: PubMed   Mentions: 49     Fields:    Translation:Cells
    150. Unwinding of nucleosomal DNA by a DNA helicase. J Biol Chem. 1995 Feb 03; 270(5):2024-31. Eggleston AK, O'Neill TE, Bradbury EM, Kowalczykowski SC. PMID: 7836428.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    151. Biochemistry of homologous recombination in Escherichia coli. Microbiol Rev. 1994 Sep; 58(3):401-65. Kowalczykowski SC, Dixon DA, Eggleston AK, Lauder SD, Rehrauer WM. PMID: 7968921; PMCID: PMC372975.
      View in: PubMed   Mentions: 507     Fields:    Translation:Cells
    152. Reversible inactivation of the Escherichia coli RecBCD enzyme by the recombination hotspot chi in vitro: evidence for functional inactivation or loss of the RecD subunit. Proc Natl Acad Sci U S A. 1994 Apr 12; 91(8):2980-4. Dixon DA, Churchill JJ, Kowalczykowski SC. PMID: 8159691; PMCID: PMC43498.
      View in: PubMed   Mentions: 28     Fields:    Translation:Cells
    153. In vitro reconstitution of homologous recombination reactions. Experientia. 1994 Mar 15; 50(3):204-15. Kowalczykowski SC. PMID: 8143794.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    154. Homologous pairing and DNA strand-exchange proteins. Annu Rev Biochem. 1994; 63:991-1043. Kowalczykowski SC, Eggleston AK. PMID: 7979259.
      View in: PubMed   Mentions: 110     Fields:    Translation:HumansAnimals
    155. Negative co-dominant inhibition of recA protein function. Biochemical properties of the recA1, recA13 and recA56 proteins and the effect of recA56 protein on the activities of the wild-type recA protein function in vitro. J Mol Biol. 1993 Nov 05; 234(1):72-86. Lauder SD, Kowalczykowski SC. PMID: 8230208.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    156. Atomic force microscope measurements of nucleosome cores assembled along defined DNA sequences. Biochemistry. 1993 Aug 24; 32(33):8390-6. Allen MJ, Dong XF, O'Neill TE, Yau P, Kowalczykowski SC, Gatewood J, Balhorn R, Bradbury EM. PMID: 8357790.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    157. The mutant recBCD enzyme, recB2109CD enzyme, has helicase activity but does not promote efficient joint molecule formation in vitro. J Mol Biol. 1993 Jun 05; 231(3):621-33. Eggleston AK, Kowalczykowski SC. PMID: 8390578.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    158. Biochemical characterization of a mutant recBCD enzyme, the recB2109CD enzyme, which lacks chi-specific, but not non-specific, nuclease activity. J Mol Biol. 1993 Jun 05; 231(3):605-20. Eggleston AK, Kowalczykowski SC. PMID: 8390577.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    159. A single-stranded DNA binding protein from Drosophila melanogaster: characterization of the heterotrimeric protein and its interaction with single-stranded DNA. Biochemistry. 1993 May 18; 32(19):5257-66. Mitsis PG, Kowalczykowski SC, Lehman IR. PMID: 8494903.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    160. The recombination hotspot chi is a regulatory sequence that acts by attenuating the nuclease activity of the E. coli RecBCD enzyme. Cell. 1993 Apr 09; 73(1):87-96. Dixon DA, Kowalczykowski SC. PMID: 8384931.
      View in: PubMed   Mentions: 98     Fields:    Translation:Cells
    161. Alteration of the nucleoside triphosphate (NTP) catalytic domain within Escherichia coli recA protein attenuates NTP hydrolysis but not joint molecule formation. J Biol Chem. 1993 Jan 15; 268(2):1292-7. Rehrauer WM, Kowalczykowski SC. PMID: 8419331.
      View in: PubMed   Mentions: 53     Fields:    Translation:Cells
    162. Enzymatic properties of the RecA803 protein, a partial suppressor of recF mutations. Biochemistry. 1992 Nov 03; 31(43):10529-35. Madiraju MV, Lavery PE, Kowalczykowski SC, Clark AJ. PMID: 1420169.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    163. Biochemical basis of the constitutive repressor cleavage activity of recA730 protein. A comparison to recA441 and recA803 proteins. J Biol Chem. 1992 Oct 15; 267(29):20648-58. Lavery PE, Kowalczykowski SC. PMID: 1400384.
      View in: PubMed   Mentions: 44     Fields:    Translation:Cells
    164. The physical and enzymatic properties of Escherichia coli recA protein display anion-specific inhibition. J Biol Chem. 1992 May 25; 267(15):10400-4. Menetski JP, Varghese A, Kowalczykowski SC. PMID: 1350278.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    165. A postsynaptic role for single-stranded DNA-binding protein in recA protein-promoted DNA strand exchange. J Biol Chem. 1992 May 05; 267(13):9315-20. Lavery PE, Kowalczykowski SC. PMID: 1533628.
      View in: PubMed   Mentions: 30     Fields:    Translation:Cells
    166. Enhancement of recA protein-promoted DNA strand exchange activity by volume-occupying agents. J Biol Chem. 1992 May 05; 267(13):9307-14. Lavery PE, Kowalczykowski SC. PMID: 1533627.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    167. Processivity of the DNA helicase activity of Escherichia coli recBCD enzyme. J Biol Chem. 1992 Feb 25; 267(6):4207-14. Roman LJ, Eggleston AK, Kowalczykowski SC. PMID: 1310990.
      View in: PubMed   Mentions: 35     Fields:    Translation:Cells
    168. Homologous pairing in vitro stimulated by the recombination hotspot, Chi. Cell. 1991 Jul 26; 66(2):361-71. Dixon DA, Kowalczykowski SC. PMID: 1855256.
      View in: PubMed   Mentions: 59     Fields:    Translation:Cells
    169. RecBCD-dependent joint molecule formation promoted by the Escherichia coli RecA and SSB proteins. Proc Natl Acad Sci U S A. 1991 Apr 15; 88(8):3367-71. Roman LJ, Dixon DA, Kowalczykowski SC. PMID: 2014257; PMCID: PMC51448.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    170. Asymmetry in the recA protein-DNA filament. J Biol Chem. 1991 Mar 25; 266(9):5450-8. Lauder SD, Kowalczykowski SC. PMID: 1826000.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    171. An overview of homologous pairing and DNA strand exchange proteins. Biochimie. 1991 Feb-Mar; 73(2-3):163-76. Eggleston AK, Kowalczykowski SC. PMID: 1653031.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    172. Biochemical and biological function of Escherichia coli RecA protein: behavior of mutant RecA proteins. Biochimie. 1991 Feb-Mar; 73(2-3):289-304. Kowalczykowski SC. PMID: 1883888.
      View in: PubMed   Mentions: 34     Fields:    Translation:Cells
    173. Biochemistry of genetic recombination: energetics and mechanism of DNA strand exchange. Annu Rev Biophys Biophys Chem. 1991; 20:539-75. Kowalczykowski SC. PMID: 1831022.
      View in: PubMed   Mentions: 79     Fields:    Translation:Cells
    174. Properties of recA441 protein-catalyzed DNA strand exchange can be attributed to an enhanced ability to compete with SSB protein. J Biol Chem. 1990 Mar 05; 265(7):4004-10. Lavery PE, Kowalczykowski SC. PMID: 2406267.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    175. Biochemical properties of the Escherichia coli recA430 protein. Analysis of a mutation that affects the interaction of the ATP-recA protein complex with single-stranded DNA. J Mol Biol. 1990 Feb 20; 211(4):845-55. Menetski JP, Kowalczykowski SC. PMID: 2179566.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    176. Stable DNA heteroduplex formation catalyzed by the Escherichia coli RecA protein in the absence of ATP hydrolysis. Proc Natl Acad Sci U S A. 1990 Jan; 87(1):21-5. Menetski JP, Bear DG, Kowalczykowski SC. PMID: 2404275; PMCID: PMC53191.
      View in: PubMed   Mentions: 95     Fields:    Translation:Cells
    177. Formation of heteroduplex DNA promoted by the combined activities of Escherichia coli recA and recBCD proteins. J Biol Chem. 1989 Nov 05; 264(31):18340-8. Roman LJ, Kowalczykowski SC. PMID: 2681196.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    178. Purification and characterization of the coliphage N4-coded single-stranded DNA binding protein. J Biol Chem. 1989 Jul 25; 264(21):12700-8. Lindberg G, Kowalczykowski SC, Rist JK, Sugino A, Rothman-Denes LB. PMID: 2663866.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    179. Enhancement of Escherichia coli RecA protein enzymatic function by dATP. Biochemistry. 1989 Jul 11; 28(14):5871-81. Menetski JP, Kowalczykowski SC. PMID: 2673351.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    180. Biochemical events essential to the recombination activity of Escherichia coli RecA protein. I. Properties of the mutant RecA142 protein. J Mol Biol. 1989 Jun 20; 207(4):719-33. Kowalczykowski SC, Burk DL, Krupp RA. PMID: 2527303.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    181. Biochemical events essential to the recombination activity of Escherichia coli RecA protein. II. Co-dominant effects of RecA142 protein on wild-type RecA protein function. J Mol Biol. 1989 Jun 20; 207(4):735-47. Kowalczykowski SC, Krupp RA. PMID: 2527304.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    182. Characterization of the helicase activity of the Escherichia coli RecBCD enzyme using a novel helicase assay. Biochemistry. 1989 Apr 04; 28(7):2863-73. Roman LJ, Kowalczykowski SC. PMID: 2545238.
      View in: PubMed   Mentions: 73     Fields:    Translation:Cells
    183. Characterization of the adenosinetriphosphatase activity of the Escherichia coli RecBCD enzyme: relationship of ATP hydrolysis to the unwinding of duplex DNA. Biochemistry. 1989 Apr 04; 28(7):2873-81. Roman LJ, Kowalczykowski SC. PMID: 2545239.
      View in: PubMed   Mentions: 27     Fields:    Translation:Cells
    184. Increase of the DNA strand assimilation activity of recA protein by removal of the C terminus and structure-function studies of the resulting protein fragment. J Biol Chem. 1988 Oct 25; 263(30):15513-20. Benedict RC, Kowalczykowski SC. PMID: 2971666.
      View in: PubMed   Mentions: 22     Fields:    Translation:Cells
    185. Biochemical basis of the temperature-inducible constitutive protease activity of the RecA441 protein of Escherichia coli. J Mol Biol. 1988 Oct 20; 203(4):861-74. Lavery PE, Kowalczykowski SC. PMID: 2974887.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    186. Properties of the high-affinity single-stranded DNA binding state of the Escherichia coli recA protein. Biochemistry. 1988 Feb 23; 27(4):1205-12. Menetski JP, Varghese A, Kowalczykowski SC. PMID: 3284580.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    187. Properties of the duplex DNA-dependent ATPase activity of Escherichia coli RecA protein and its role in branch migration. Proc Natl Acad Sci U S A. 1987 May; 84(10):3127-31. Kowalczykowski SC, Clow J, Krupp RA. PMID: 3033635; PMCID: PMC304821.
      View in: PubMed   Mentions: 22     Fields:    Translation:Cells
    188. Transfer of recA protein from one polynucleotide to another. Kinetic evidence for a ternary intermediate during the transfer reaction. J Biol Chem. 1987 Feb 15; 262(5):2085-92. Menetski JP, Kowalczykowski SC. PMID: 3818586.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    189. Effects of Escherichia coli SSB protein on the single-stranded DNA-dependent ATPase activity of Escherichia coli RecA protein. Evidence that SSB protein facilitates the binding of RecA protein to regions of secondary structure within single-stranded DNA. J Mol Biol. 1987 Jan 05; 193(1):97-113. Kowalczykowski SC, Krupp RA. PMID: 2953903.
      View in: PubMed   Mentions: 77     Fields:    Translation:Cells
    190. Effects of the Escherichia coli SSB protein on the binding of Escherichia coli RecA protein to single-stranded DNA. Demonstration of competitive binding and the lack of a specific protein-protein interaction. J Mol Biol. 1987 Jan 05; 193(1):81-95. Kowalczykowski SC, Clow J, Somani R, Varghese A. PMID: 3295259.
      View in: PubMed   Mentions: 45     Fields:    Translation:Cells
    191. Relationship of the physical and enzymatic properties of Escherichia coli recA protein to its strand exchange activity. Biochemistry. 1986 Nov 18; 25(23):7375-85. Roman LJ, Kowalczykowski SC. PMID: 2948558.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    192. Interaction of recA protein with a photoaffinity analogue of ATP, 8-azido-ATP: determination of nucleotide cofactor binding parameters and of the relationship between ATP binding and ATP hydrolysis. Biochemistry. 1986 Oct 07; 25(20):5872-81. Kowalczykowski SC. PMID: 3539181.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    193. Cooperative and noncooperative binding of protein ligands to nucleic acid lattices: experimental approaches to the determination of thermodynamic parameters. Biochemistry. 1986 Mar 25; 25(6):1226-40. Kowalczykowski SC, Paul LS, Lonberg N, Newport JW, McSwiggen JA, von Hippel PH. PMID: 3486003.
      View in: PubMed   Mentions: 55     Fields:    Translation:Cells
    194. Interaction of recA protein with single-stranded DNA. Quantitative aspects of binding affinity modulation by nucleotide cofactors. J Mol Biol. 1985 Jan 20; 181(2):281-95. Menetski JP, Kowalczykowski SC. PMID: 3981638.
      View in: PubMed   Mentions: 82     Fields:    Translation:Cells
    195. Autoregulation of gene expression. Quantitative evaluation of the expression and function of the bacteriophage T4 gene 32 (single-stranded DNA binding) protein system. J Mol Biol. 1982 Dec 25; 162(4):795-818. von Hippel PH, Kowalczykowski SC, Lonberg N, Newport JW, Paul LS, Stormo GD, Gold L. PMID: 6984860.
      View in: PubMed   Mentions: 33     Fields:    Translation:Cells
    196. Kinetics and mechanism of the association of the bacteriophage T4 gene 32 (helix destabilizing) protein with single-stranded nucleic acids. Evidence for protein translocation. J Mol Biol. 1981 Oct 15; 152(1):67-109. Lohman TM, Kowalczykowski SC. PMID: 6279865.
      View in: PubMed   Mentions: 27     Fields:    Translation:Cells
    197. Interactions of bacteriophage T4-coded gene 32 protein with nucleic acids. III. Binding properties of two specific proteolytic digestion products of the protein (G32P*I and G32P*III). J Mol Biol. 1981 Jan 05; 145(1):123-38. Lonberg N, Kowalczykowski SC, Paul LS, von Hippel PH. PMID: 6455528.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    198. Interactions of bacteriophage T4-coded gene 32 protein with nucleic acids. II. Specificity of binding to DNA and RNA. J Mol Biol. 1981 Jan 05; 145(1):105-21. Newport JW, Lonberg N, Kowalczykowski SC, von Hippel PH. PMID: 7265197.
      View in: PubMed   Mentions: 22     Fields:    Translation:Cells
    199. On the thermodynamics and kinetics of the cooperative binding of bacteriophage T4-coded gene 32 (helix destabilizing) protein to nucleic acid lattices. Biophys J. 1980 Oct; 32(1):403-18. Kowalczykowski SC, Lonberg N, Newport JW, Paul LS, von Hippel PH. PMID: 6264988; PMCID: PMC1327320.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    Stephen's Networks
    Concepts (384)
    Derived automatically from this person's publications.
    Explore
    _
    Co-Authors (5)
    People in Profiles who have published with this person.
    Explore
    _
    Similar People (60)
    People who share similar concepts with this person.
    Explore
    _
    Same Department
    Search Department
    _

    UC Davis Profiles is managed by the UCSF Clinical and Translational Science Institute (CTSI), part of the Clinical and Translational Science Award program funded by the National Center for Advancing Translational Sciences (Grant Number UL1 TR000004) at the National Institutes of Health (NIH).
    This site is running Profiles RNS version UCSF-v3.1.0-6-g69de2244 on PROFILES-PWEB03. We use cookies to operate our website. We also use cookies to analyze our site’s performance and improve your experience on our site. For more information about how we use cookies, please see our Website Terms of Use.

    Copyright © The Regents of the University of California