Colin Reardon

Title(s)Associate Professor, School of Veterinary Medicine
SchoolSchool of Veterinary Medicine
CA 95616
vCardDownload vCard

    Collapse Research 
    Collapse Research Activities and Funding
    Role of sensory neurons in host resistance to enteric bacterial pathogens
    NIH R21AI148188Jul 1, 2020 - Jun 30, 2022
    Role: Principal Investigator
    Zeiss Light Sheet Z1 Microscope
    NIH S10OD026719May 1, 2020 - Apr 30, 2021
    Role: Principal Investigator
    Coordination of mucosal immune response to enteric bacterial pathogens by nociceptive innervation
    NIH R01AI150647Apr 1, 2020 - Mar 31, 2025
    Role: Principal Investigator
    Neuro-immune mediated control of mucosal immunity
    NIH R21AI133116Jun 9, 2017 - May 31, 2020
    Role: Principal Investigator
    Mapping of the neuro-immune interface
    NIH OT2OD023871Feb 1, 2017 - Mar 31, 2020
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Substance P receptor signaling contributes to host maladaptive responses during enteric bacterial infection. bioRxiv. 2024 Jun 27. Cremin M, Ramirez VT, Sanchez K, Tay E, Murray K, Brust-Mascher I, Reardon C. PMID: 38979288; PMCID: PMC11230291.
      View in: PubMed   Mentions:
    2. Comment on "No consistent evidence for the anti-inflammatory effect of vagus nerve stimulation in humans: A systematic review and meta-analysis". Brain Behav Immun. 2024 Jul; 119:1018. Reardon C. PMID: 38447885.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. PrestoCell: A persistence-based clustering approach for rapid and robust segmentation of cellular morphology in three-dimensional data. PLoS One. 2024; 19(2):e0299006. Wu Y, Brust-Mascher I, Gareau MG, De Loera JA, Reardon C. PMID: 38422108; PMCID: PMC10903871.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    4. TRPV1 controls innate immunity during Citrobacter rodentium enteric infection. PLoS Pathog. 2023 Dec; 19(12):e1011576. Cremin M, Tay EXY, Ramirez VT, Murray K, Nichols RK, Brust-Mascher I, Reardon C. PMID: 38109366; PMCID: PMC10758261.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    5. TRPV1 controls innate immunity during Citrobacter rodentium enteric infection. bioRxiv. 2023 Jul 27. Cremin M, Tay E, Ramirez VT, Murray K, Nichols RK, Brust-Mascher I, Reardon C. PMID: 37546968; PMCID: PMC10402119.
      View in: PubMed   Mentions:
    6. The diversity of neuroimmune circuits controlling lung inflammation. Am J Physiol Lung Cell Mol Physiol. 2023 01 01; 324(1):L53-L63. Cremin M, Schreiber S, Murray K, Tay EXY, Reardon C. PMID: 36410021; PMCID: PMC9829467.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Untangling webs of divergent neuroimmune circuits. J Physiol. 2022 10; 600(20):4383-4384. Reardon C. PMID: 36073291.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Neonatal Enteropathogenic Escherichia coli Infection Disrupts Microbiota-Gut-Brain Axis Signaling. Infect Immun. 2021 08 16; 89(9):e0005921. Hennessey C, Keogh CE, Barboza M, Brust-Mascher I, Knotts TA, Sladek JA, Pusceddu MM, Stokes P, Rabasa G, Honeycutt M, Walsh O, Nichols R, Reardon C, Gareau MG. PMID: 33820817; PMCID: PMC8370682.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    9. Divergence of neuroimmune circuits activated by afferent and efferent vagal nerve stimulation in the regulation of inflammation. J Physiol. 2021 04; 599(7):2075-2084. Murray K, Rude KM, Sladek J, Reardon C. PMID: 33491187; PMCID: PMC8016722.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    10. Neural Immune Communication in the Control of Host-Bacterial Pathogen Interactions in the Gastrointestinal Tract. Infect Immun. 2020 08 19; 88(9). Ramirez V, Swain S, Murray K, Reardon C. PMID: 32341116; PMCID: PMC7440759.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    11. Sensory Nociceptive Neurons Contribute to Host Protection During Enteric Infection With Citrobacter rodentium. J Infect Dis. 2020 06 11; 221(12):1978-1988. Ramirez VT, Sladek J, Godinez DR, Rude KM, Chicco P, Murray K, Brust-Mascher I, Gareau MG, Reardon C. PMID: 31960920; PMCID: PMC7289549.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    12. Nod-like receptors are critical for gut-brain axis signalling in mice. J Physiol. 2019 12; 597(24):5777-5797. Pusceddu MM, Barboza M, Keogh CE, Schneider M, Stokes P, Sladek JA, Kim HJD, Torres-Fuentes C, Goldfild LR, Gillis SE, Brust-Mascher I, Rabasa G, Wong KA, Lebrilla C, Byndloss MX, Maisonneuve C, Bäumler AJ, Philpott DJ, Ferrero RL, Barrett KE, Reardon C, Gareau MG. PMID: 31652348; PMCID: PMC6911019.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    13. Functional circuitry of neuro-immune communication in the mesenteric lymph node and spleen. Brain Behav Immun. 2019 11; 82:214-223. Murray K, Barboza M, Rude KM, Brust-Mascher I, Reardon C. PMID: 31445965; PMCID: PMC6800652.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    14. T-cell derived acetylcholine aids host defenses during enteric bacterial infection with Citrobacter rodentium. PLoS Pathog. 2019 04; 15(4):e1007719. Ramirez VT, Godinez DR, Brust-Mascher I, Nonnecke EB, Castillo PA, Gardner MB, Tu D, Sladek JA, Miller EN, Lebrilla CB, Bevins CL, Gareau MG, Reardon C. PMID: 30973939; PMCID: PMC6478367.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    15. Adenylyl Cyclase 6 Mediates Inhibition of TNF in the Inflammatory Reflex. Front Immunol. 2018; 9:2648. Tarnawski L, Reardon C, Caravaca AS, Rosas-Ballina M, Tusche MW, Drake AR, Hudson LK, Hanes WM, Li JH, Parrish WR, Ojamaa K, Al-Abed Y, Faltys M, Pavlov VA, Andersson U, Chavan SS, Levine YA, Mak TW, Tracey KJ, Olofsson PS. PMID: 30538698; PMCID: PMC6277584.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    16. Neuroimmune Communication in Health and Disease. Physiol Rev. 2018 10 01; 98(4):2287-2316. Reardon C, Murray K, Lomax AE. PMID: 30109819; PMCID: PMC6170975.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    17. The cholinergic anti-inflammatory pathway revisited. Neurogastroenterol Motil. 2018 03; 30(3). Murray K, Reardon C. PMID: 29468816; PMCID: PMC5826620.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    18. Neuroanatomy of the spleen: Mapping the relationship between sympathetic neurons and lymphocytes. PLoS One. 2017; 12(7):e0182416. Murray K, Godinez DR, Brust-Mascher I, Miller EN, Gareau MG, Reardon C. PMID: 28753658; PMCID: PMC5533443.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    19. The IgM receptor FcμR limits tonic BCR signaling by regulating expression of the IgM BCR. Nat Immunol. 2017 03; 18(3):321-333. Nguyen TT, Kläsener K, Zürn C, Castillo PA, Brust-Mascher I, Imai DM, Bevins CL, Reardon C, Reth M, Baumgarth N. PMID: 28135254; PMCID: PMC5310993.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    20. A Convenient Method for Evaluating Epithelial Cell Proliferation in the Whole Mammary Glands of Female Mice. Endocrinology. 2016 Oct; 157(10):3742-3748. Berryhill GE, Brust-Mascher I, Huynh JH, Famula TR, Reardon C, Hovey RC. PMID: 27571136; PMCID: PMC5045499.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    21. Neuro-immune interactions in the cholinergic anti-inflammatory reflex. Immunol Lett. 2016 10; 178:92-6. Reardon C. PMID: 27542331.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    22. Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation. Cell Stem Cell. 2016 08 04; 19(2):205-216. Dominguez-Brauer C, Hao Z, Elia AJ, Fortin JM, Nechanitzky R, Brauer PM, Sheng Y, Mana MD, Chio IIC, Haight J, Pollett A, Cairns R, Tworzyanski L, Inoue S, Reardon C, Marques A, Silvester J, Cox MA, Wakeham A, Yilmaz OH, Sabatini DM, van Es JH, Clevers H, Sato T, Mak TW. PMID: 27184401; PMCID: PMC5193118.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    23. Modulation of the microbiota-gut-brain axis by probiotics in a murine model of inflammatory bowel disease. Am J Physiol Gastrointest Liver Physiol. 2016 06 01; 310(11):G989-98. Emge JR, Huynh K, Miller EN, Kaur M, Reardon C, Barrett KE, Gareau MG. PMID: 27056723.
      View in: PubMed   Mentions: 56     Fields:    Translation:Animals
    24. T-cell STAT3 is required for the maintenance of humoral immunity to LCMV. Eur J Immunol. 2015 Feb; 45(2):418-27. McIlwain DR, Grusdat M, Pozdeev VI, Xu HC, Shinde P, Reardon C, Hao Z, Beyer M, Bergthaler A, Häussinger D, Nolan GP, Lang KS, Lang PA. PMID: 25393615; PMCID: PMC4383653.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    25. Helicobacter pylori inhibits dendritic cell maturation via interleukin-10-mediated activation of the signal transducer and activator of transcription 3 pathway. J Innate Immun. 2015; 7(2):199-211. Rizzuti D, Ang M, Sokollik C, Wu T, Abdullah M, Greenfield L, Fattouh R, Reardon C, Tang M, Diao J, Schindler C, Cattral M, Jones NL. PMID: 25412627; PMCID: PMC6738898.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    26. Probiotics normalize the gut-brain-microbiota axis in immunodeficient mice. Am J Physiol Gastrointest Liver Physiol. 2014 Oct 15; 307(8):G793-802. Smith CJ, Emge JR, Berzins K, Lung L, Khamishon R, Shah P, Rodrigues DM, Sousa AJ, Reardon C, Sherman PM, Barrett KE, Gareau MG. PMID: 25190473; PMCID: PMC4200314.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    27. Unique lamina propria stromal cells imprint the functional phenotype of mucosal dendritic cells. Mucosal Immunol. 2015 Jan; 8(1):141-51. Vicente-Suarez I, Larange A, Reardon C, Matho M, Feau S, Chodaczek G, Park Y, Obata Y, Gold R, Wang-Zhu Y, Lena C, Zajonc DM, Schoenberger SP, Kronenberg M, Cheroutre H. PMID: 24938743; PMCID: PMC4268120.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    28. Toso controls encephalitogenic immune responses by dendritic cells and regulatory T cells. Proc Natl Acad Sci U S A. 2014 Jan 21; 111(3):1060-5. Brenner D, Brüstle A, Lin GH, Lang PA, Duncan GS, Knobbe-Thomsen CB, St Paul M, Reardon C, Tusche MW, Snow B, Hamilton SR, Pfefferle A, Gilani SO, Ohashi PS, Lang KS, Mak TW. PMID: 24398517; PMCID: PMC3903229.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    29. Lymphocyte-derived ACh regulates local innate but not adaptive immunity. Proc Natl Acad Sci U S A. 2013 Jan 22; 110(4):1410-5. Reardon C, Duncan GS, Brüstle A, Brenner D, Tusche MW, Olofsson PS, Olofsson P, Rosas-Ballina M, Tracey KJ, Mak TW. PMID: 23297238; PMCID: PMC3557089.
      View in: PubMed   Mentions: 93     Fields:    Translation:AnimalsCells
    30. The NF-κB regulator MALT1 determines the encephalitogenic potential of Th17 cells. J Clin Invest. 2012 Dec; 122(12):4698-709. Brüstle A, Brenner D, Knobbe CB, Lang PA, Virtanen C, Hershenfield BM, Reardon C, Lacher SM, Ruland J, Ohashi PS, Mak TW. PMID: 23114599; PMCID: PMC3590210.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    31. Acetylcholine-synthesizing T cells relay neural signals in a vagus nerve circuit. Science. 2011 Oct 07; 334(6052):98-101. Rosas-Ballina M, Olofsson PS, Ochani M, Valdés-Ferrer SI, Levine YA, Reardon C, Tusche MW, Pavlov VA, Andersson U, Chavan S, Mak TW, Tracey KJ. PMID: 21921156; PMCID: PMC4548937.
      View in: PubMed   Mentions: 653     Fields:    Translation:AnimalsCells
    32. Nucleotide oligomerization domain-containing proteins instruct T cell helper type 2 immunity through stromal activation. Proc Natl Acad Sci U S A. 2011 Sep 06; 108(36):14896-901. Magalhaes JG, Rubino SJ, Travassos LH, Le Bourhis L, Duan W, Sellge G, Geddes K, Geddes K, Reardon C, Lechmann M, Carneiro LA, Selvanantham T, Fritz JH, Taylor BC, Artis D, Mak TW, Comeau MR, Croft M, Girardin SE, Philpott DJ. PMID: 21856952; PMCID: PMC3169112.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCellsPHPublic Health
    33. Thymic stromal lymphopoetin-induced expression of the endogenous inhibitory enzyme SLPI mediates recovery from colonic inflammation. Immunity. 2011 Aug 26; 35(2):223-35. Reardon C, Lechmann M, Brüstle A, Gareau MG, Shuman N, Philpott D, Ziegler SF, Mak TW. PMID: 21820333; PMCID: PMC3169330.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    34. Probiotics prevent death caused by Citrobacter rodentium infection in neonatal mice. J Infect Dis. 2010 Jan 01; 201(1):81-91. Gareau MG, Wine E, Reardon C, Sherman PM. PMID: 19961304.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    35. cIAP proteins: keystones in NOD receptor signal transduction. Immunity. 2009 Jun 19; 30(6):755-6. Reardon C, Mak TW. PMID: 19538923.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    36. Transient local depletion of Foxp3+ regulatory T cells during recovery from colitis via Fas/Fas ligand-induced death. J Immunol. 2008 Jun 15; 180(12):8316-26. Reardon C, Wang A, McKay DM. PMID: 18523298.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    37. TGF-beta suppresses IFN-gamma-STAT1-dependent gene transcription by enhancing STAT1-PIAS1 interactions in epithelia but not monocytes/macrophages. J Immunol. 2007 Apr 01; 178(7):4284-95. Reardon C, McKay DM. PMID: 17371985.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    38. Characterization of the immuno-regulatory response to the tapeworm Hymenolepis diminuta in the non-permissive mouse host. Int J Parasitol. 2007 Mar; 37(3-4):393-403. Persaud R, Wang A, Reardon C, McKay DM. PMID: 17092505.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    39. Transforming growth factor-beta regulation of epithelial tight junction proteins enhances barrier function and blocks enterohemorrhagic Escherichia coli O157:H7-induced increased permeability. Am J Pathol. 2005 Dec; 167(6):1587-97. Howe KL, Reardon C, Wang A, Nazli A, McKay DM. PMID: 16314472; PMCID: PMC1613202.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansCells
    40. Tapeworm infection reduces epithelial ion transport abnormalities in murine dextran sulfate sodium-induced colitis. Infect Immun. 2001 Jul; 69(7):4417-23. Reardon C, Sanchez A, Hogaboam CM, McKay DM. PMID: 11401981; PMCID: PMC98514.
      View in: PubMed   Mentions: 33     Fields:    Translation:Animals