Jan Paul Muizelaar

Title(s)Professor Emeritus, Neurological Surgery
SchoolSchool of Medicine
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    1. Multiple extraspinal recurrences of ependymoma 13 years after spinal cordectomy: case report. J Neurosurg Spine. 2018 07; 29(1):92-96. Whitaker-Lea WA, Graham RS, Muizelaar JP, Richard HT. PMID: 29701571.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Proposal for the Rapid Reversal of Coagulopathy in Patients with Nonoperative Head Injuries on Anticoagulants and/or Antiplatelet Agents: A Case Study and Literature Review. Neurosurgery. 2017 Dec 01; 81(6):899-909. Watson VL, Louis N, Seminara BV, Muizelaar JP, Alberico A. PMID: 28368482.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    3. Septohippocampal Neuromodulation Improves Cognition after Traumatic Brain Injury. J Neurotrauma. 2015 Nov 15; 32(22):1822-32. Lee DJ, Gurkoff GG, Izadi A, Seidl SE, Echeverri A, Melnik M, Berman RF, Ekstrom AD, Muizelaar JP, Lyeth BG, Shahlaie K. PMID: 26096267; PMCID: PMC4702430.
      View in: PubMed   Mentions: 32     Fields:    Translation:Animals
    4. Multimodal monitoring after traumatic brain injury: useless or useful? Crit Care Med. 2015 Feb; 43(2):506-7. Muizelaar JP. PMID: 25599489.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    5. Computed tomography characteristics in pediatric versus adult traumatic brain injury. J Neurosurg Pediatr. 2014 Mar; 13(3):307-14. Sarkar K, Keachie K, Nguyen U, Muizelaar JP, Zwienenberg-Lee M, Shahlaie K. PMID: 24410128.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    6. Comparison of hypothermia and normothermia after severe traumatic brain injury in children (Cool Kids): a phase 3, randomised controlled trial. Lancet Neurol. 2013 Jun; 12(6):546-53. Adelson PD, Wisniewski SR, Beca J, Brown SD, Bell M, Muizelaar JP, Okada P, Beers SR, Balasubramani GK, Hirtz D, Paediatric Traumatic Brain Injury Consortium. PMID: 23664370.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansCTClinical Trials
    7. Decompressive craniectomy using gelatin film and future bone flap replacement. J Neurosurg. 2013 Apr; 118(4):776-82. Oladunjoye AO, Schrot RJ, Zwienenberg-Lee M, Muizelaar JP, Shahlaie K. PMID: 23394343.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    8. Medial septal nucleus theta frequency deep brain stimulation improves spatial working memory after traumatic brain injury. J Neurotrauma. 2013 Jan 15; 30(2):131-9. Lee DJ, Gurkoff GG, Izadi A, Berman RF, Ekstrom AD, Muizelaar JP, Lyeth BG, Shahlaie K. PMID: 23016534.
      View in: PubMed   Mentions: 42     Fields:    Translation:Animals
    9. Neuroprotective effects of SNX-185 in an in vitro model of TBI with a second insult. Restor Neurol Neurosci. 2013; 31(2):141-53. Shahlaie K, Gurkoff GG, Lyeth BG, Muizelaar JP, Berman RF. PMID: 23247061.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    10. Presentations and outcomes of children with intraventricular hemorrhages after blunt head trauma. Arch Pediatr Adolesc Med. 2012 Aug; 166(8):725-31. Lichenstein R, Glass TF, Quayle KS, Wootton-Gorges SL, Wisner DH, Miskin M, Muizelaar JP, Badawy M, Atabaki S, Holmes JF, Kuppermann N, Traumatic Brain Injury Study Group of the Pediatric Emergency Care Applied Research Network (PECARN). PMID: 22473883.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    11. A multicenter, single-blind, prospective randomized trial to evaluate the safety of a polyethylene glycol hydrogel (Duraseal Dural Sealant System) as a dural sealant in cranial surgery. World Neurosurg. 2012 Nov; 78(5):498-504. Osbun JW, Ellenbogen RG, Chesnut RM, Chin LS, Connolly PJ, Cosgrove GR, Delashaw JB, Golfinos JG, Greenlee JD, Haines SJ, Jallo J, Muizelaar JP, Nanda A, Shaffrey M, Shah MV, Tew JM, van Loveren HR, Weinand ME, White JA, Wilberger JE. PMID: 22381303.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    12. World Federation of Neurologic Surgeons grade V ... rationed care or rational care? Crit Care Med. 2011 Dec; 39(12):2778-9. Madden LK, Muizelaar JP. PMID: 22094515.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Risk factors for posttraumatic vasospasm. J Neurosurg. 2011 Sep; 115(3):602-11. Shahlaie K, Keachie K, Hutchins IM, Rudisill N, Madden LK, Smith KA, Ko KA, Latchaw RE, Muizelaar JP. PMID: 21663415.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    14. Anemia in the setting of traumatic brain injury: the arguments for and against liberal transfusion. J Neurotrauma. 2011 Jan; 28(1):155-65. Utter GH, Shahlaie K, Zwienenberg-Lee M, Muizelaar JP. PMID: 20954887.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimals
    15. Hippocampal θ dysfunction after lateral fluid percussion injury. J Neurotrauma. 2010 Sep; 27(9):1605-15. Fedor M, Berman RF, Muizelaar JP, Lyeth BG. PMID: 20597686; PMCID: PMC2966852.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    16. Definition of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage as an outcome event in clinical trials and observational studies: proposal of a multidisciplinary research group. Stroke. 2010 Oct; 41(10):2391-5. Vergouwen MD, Vermeulen M, van Gijn J, Rinkel GJ, Wijdicks EF, Muizelaar JP, Mendelow AD, Juvela S, Yonas H, Terbrugge KG, Macdonald RL, Diringer MN, Broderick JP, Dreier JP, Roos YB. PMID: 20798370.
      View in: PubMed   Mentions: 502     Fields:    Translation:Humans
    17. Upper thoracic spine arthroplasty via the anterior approach. J Neurosurg Spine. 2010 Aug; 13(2):240-5. Keachie K, Shahlaie K, Muizelaar JP. PMID: 20672961.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    18. (In)appropriate neurosurgical consultation. Clin Neurol Neurosurg. 2010 Nov; 112(9):775-80. van Essen TA, Heeringa JJ, Muizelaar JP. PMID: 20615612.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    19. Neuroprotective effects of selective N-type VGCC blockade on stretch-injury-induced calcium dynamics in cortical neurons. J Neurotrauma. 2010 Jan; 27(1):175-87. Shahlaie K, Lyeth BG, Gurkoff GG, Muizelaar JP, Berman RF. PMID: 19772476; PMCID: PMC2824229.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    20. Identification of children at very low risk of clinically-important brain injuries after head trauma: a prospective cohort study. Lancet. 2009 Oct 03; 374(9696):1160-70. Kuppermann N, Holmes JF, Dayan PS, Hoyle JD, Atabaki SM, Holubkov R, Nadel FM, Monroe D, Stanley RM, Borgialli DA, Badawy MK, Schunk JE, Quayle KS, Mahajan P, Lichenstein R, Lillis KA, Tunik MG, Jacobs ES, Callahan JM, Gorelick MH, Glass TF, Lee LK, Bachman MC, Cooper A, Powell EC, Gerardi MJ, Melville KA, Muizelaar JP, Wisner DH, Zuspan SJ, Dean JM, Wootton-Gorges SL, Pediatric Emergency Care Applied Research Network (PECARN). PMID: 19758692.
      View in: PubMed   Mentions: 334     Fields:    Translation:Humans
    21. Hypertonic saline in neurocritical care: Is continuous infusion appropriate? Crit Care Med. 2009 Apr; 37(4):1521-3. Muizelaar JP, Shahlaie K. PMID: 19318850.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    22. Transfusion practices for acute traumatic brain injury: a survey of physicians at US trauma centers. Intensive Care Med. 2009 Mar; 35(3):480-8. Sena MJ, Rivers RM, Muizelaar JP, Battistella FD, Utter GH. PMID: 18854976.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    23. Abnormal responses of the human cerebral microcirculation to papaverin during aneurysm surgery. Stroke. 2009 Jan; 40(1):317-20. Pennings FA, Albrecht KW, Muizelaar JP, Schuurman PR, Bouma GJ. PMID: 18845800.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    24. Posttraumatic vasospasm detected by continuous brain tissue oxygen monitoring: treatment with intraarterial verapamil and balloon angioplasty. Neurocrit Care. 2009; 10(1):61-9. Shahlaie K, Boggan JE, Latchaw RE, Ji C, Muizelaar JP. PMID: 18807219.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    25. Progression of traumatic intracerebral hemorrhage: a prospective observational study. J Neurotrauma. 2008 Jun; 25(6):629-39. Narayan RK, Maas AI, Servadei F, Skolnick BE, Tillinger MN, Marshall LF, Traumatic Intracerebral Hemorrhage Study Group. PMID: 18491950.
      View in: PubMed   Mentions: 79     Fields:    Translation:Humans
    26. Chronic hypopituitarism after traumatic brain injury: risk assessment and relationship to outcome. Neurosurgery. 2008 May; 62(5):1080-93; discussion 1093-4. Bavisetty S, Bavisetty S, McArthur DL, Dusick JR, Wang C, Cohan P, Boscardin WJ, Swerdloff R, Levin H, Chang DJ, Muizelaar JP, Kelly DF. PMID: 18580806.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    27. Effect of prophylactic transluminal balloon angioplasty on cerebral vasospasm and outcome in patients with Fisher grade III subarachnoid hemorrhage: results of a phase II multicenter, randomized, clinical trial. Stroke. 2008 Jun; 39(6):1759-65. Zwienenberg-Lee M, Hartman J, Rudisill N, Madden LK, Smith K, Eskridge J, Newell D, Verweij B, Bullock MR, Baker A, Coplin W, Mericle R, Dai J, Rocke D, Muizelaar JP, Balloon Prophylaxis for Aneurysmal Vasospasm (BPAV) Study Group. PMID: 18420953.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCTClinical Trials
    28. Current concepts of cerebral oxygen transport and energy metabolism after severe traumatic brain injury. Prog Brain Res. 2007; 161:111-24. Verweij BH, Amelink GJ, Muizelaar JP. PMID: 17618973.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    29. Endovascular management of cerebral vasospasm. Neurosurgery. 2006 Nov; 59(5 Suppl 3):S139-47; discussion S3-13. Zwienenberg-Lee M, Hartman J, Rudisill N, Muizelaar JP. PMID: 17053596.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    30. Efficacy and safety of dexanabinol in severe traumatic brain injury: results of a phase III randomised, placebo-controlled, clinical trial. Lancet Neurol. 2006 Jan; 5(1):38-45. Maas AI, Murray G, Henney H, Kassem N, Legrand V, Mangelus M, Muizelaar JP, Stocchetti N, Knoller N, Pharmos TBI investigators. PMID: 16361021.
      View in: PubMed   Mentions: 100     Fields:    Translation:HumansCTClinical Trials
    31. Acute secondary adrenal insufficiency after traumatic brain injury: a prospective study. Crit Care Med. 2005 Oct; 33(10):2358-66. Cohan P, Wang C, McArthur DL, Cook SW, Dusick JR, Armin B, Swerdloff R, Vespa P, Muizelaar JP, Cryer HG, Christenson PD, Kelly DF. PMID: 16215393.
      View in: PubMed   Mentions: 81     Fields:    Translation:Humans
    32. Diffusion-weighted imaging of edema following traumatic brain injury in rats: effects of secondary hypoxia. J Neurotrauma. 2005 Aug; 22(8):857-72. Van Putten HP, Bouwhuis MG, Muizelaar JP, Lyeth BG, Berman RF. PMID: 16083353.
      View in: PubMed   Mentions: 33     Fields:    Translation:Animals
    33. Phase II clinical trial of moderate hypothermia after severe traumatic brain injury in children. Neurosurgery. 2005 Apr; 56(4):740-54; discussion 740-54. Adelson PD, Ragheb J, Kanev P, Brockmeyer D, Beers SR, Brown SD, Cassidy LD, Chang Y, Levin H. PMID: 15792513.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansCTClinical Trials
    34. When it is not cervical radiculopathy: thoracic outlet syndrome--a prospective study on diagnosis and treatment. Clin Neurosurg. 2005; 52:243-9. Muizelaar JP, Zwienenberg-Lee M. PMID: 16626077.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    35. Sugar or salt? Crit Care Med. 2005 Jan; 33(1):257-8. Schrot RJ, Muizelaar JP. PMID: 15644693.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    36. Neuroprotection in the rat lateral fluid percussion model of traumatic brain injury by SNX-185, an N-type voltage-gated calcium channel blocker. Exp Neurol. 2004 Nov; 190(1):70-8. Lee LL, Galo E, Lyeth BG, Muizelaar JP, Berman RF. PMID: 15473981.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    37. Comparison of behavioral deficits and acute neuronal degeneration in rat lateral fluid percussion and weight-drop brain injury models. J Neurotrauma. 2004 May; 21(5):521-39. Hallam TM, Floyd CL, Folkerts MM, Lee LL, Gong QZ, Lyeth BG, Muizelaar JP, Berman RF. PMID: 15165361.
      View in: PubMed   Mentions: 63     Fields:    Translation:Animals
    38. Early loss of astrocytes after experimental traumatic brain injury. Glia. 2003 Nov; 44(2):140-52. Zhao X, Ahram A, Berman RF, Muizelaar JP, Lyeth BG. PMID: 14515330.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    39. Transluminal balloon angioplasty improves brain tissue oxygenation and metabolism in severe vasospasm after aneurysmal subarachnoid hemorrhage: case report. Neurosurgery. 2003 Apr; 52(4):970-4; discussion 974-6. Hoelper BM, Hofmann E, Sporleder R, Soldner F, Behr R. PMID: 12657196.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    40. Comparison of cerebral blood flow in computed tomographic hypodense areas of the brain in head-injured patients. Neurosurgery. 2003 Feb; 52(2):340-5; discussion 345-6. Furuya Y, Hlatky R, Valadka AB, Diaz P, Robertson CS. PMID: 12535362.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    41. Optimal temperature for the management of severe traumatic brain injury: effect of hypothermia on intracranial pressure, systemic and intracranial hemodynamics, and metabolism. Neurosurgery. 2003 Jan; 52(1):102-11; discussion 111-2. Tokutomi T, Morimoto K, Miyagi T, Yamaguchi S, Ishikawa K, Shigemori M. PMID: 12493106.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    42. Mannitol in acute traumatic brain injury. Lancet. 2002 May 11; 359(9318):1633-4. Schrot RJ, Muizelaar JP. PMID: 12020522.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    43. Clinical trials in head injury. J Neurotrauma. 2002 May; 19(5):503-57. Narayan RK, Michel ME, Ansell B, Baethmann A, Biegon A, Bracken MB, Bullock MR, Choi SC, Clifton GL, Contant CF, Coplin WM, Dietrich WD, Ghajar J, Grady SM, Grossman RG, Hall ED, Heetderks W, Hovda DA, Jallo J, Katz RL, Knoller N, Kochanek PM, Maas AI, Majde J, Marion DW, Marmarou A, Marshall LF, McIntosh TK, Miller E, Mohberg N, Muizelaar JP, Pitts LH, Quinn P, Riesenfeld G, Robertson CS, Strauss KI, Teasdale G, Temkin N, Tuma R, Wade C, Walker MD, Weinrich M, Whyte J, Wilberger J, Young AB, Yurkewicz L. PMID: 12042091; PMCID: PMC1462953.
      View in: PubMed   Mentions: 319     Fields:    Translation:Humans
    44. Blood flow and ischemia within traumatic cerebral contusions. Neurosurgery. 2002 Apr; 50(4):781-8; discussion 788-90. von Oettingen G, Bergholt B, Gyldensted C, Astrup J. PMID: 11904029.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    45. Hypothermia on admission in patients with severe brain injury. J Neurotrauma. 2002 Mar; 19(3):293-301. Clifton GL, Miller ER, Choi SC, Levin HS, McCauley S, Smith KR, Muizelaar JP, Marion DW, Luerssen TG. PMID: 11939497.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCTClinical Trials
    46. The need for a quantifiable normalized transcranial Doppler ratio for the diagnosis of posterior circulation vasospasm. Stroke. 2002 Jan; 33(1):78. Muizelaar Jp. PMID: 11813696.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    47. Intercenter variance. J Neurosurg. 2001 Nov; 95(5):733-4. Marshall LF. PMID: 11702860.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    48. Intercenter variance in clinical trials of head trauma--experience of the National Acute Brain Injury Study: Hypothermia. J Neurosurg. 2001 Nov; 95(5):751-5. Clifton GL, Choi SC, Miller ER, Levin HS, Smith KR, Muizelaar JP, Wagner FC, Marion DW, Luerssen TG. PMID: 11702863.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    49. Hyperacute measurement of intracranial pressure, cerebral perfusion pressure, jugular venous oxygen saturation, and laser Doppler flowmetry, before and during removal of traumatic acute subdural hematoma. J Neurosurg. 2001 Oct; 95(4):569-72. Verweij BH, Muizelaar JP, Vinas FC. PMID: 11596950.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    50. The effect of groups II and III metabotropic glutamate receptor activation on neuronal injury in a rodent model of traumatic brain injury. Neurosurgery. 2001 May; 48(5):1119-26; discussion 1126-7. Zwienenberg M, Gong QZ, Berman RF, Muizelaar JP, Lyeth BG. PMID: 11334279.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    51. Group I metabotropic glutamate antagonist reduces acute neuronal degeneration and behavioral deficits after traumatic brain injury in rats. Exp Neurol. 2001 May; 169(1):191-9. Lyeth BG, Gong QZ, Shields S, Muizelaar JP, Berman RF. PMID: 11312571.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    52. Cerebral perfusion and blood flow in neurotrauma. Neurol Res. 2001 Mar-Apr; 23(2-3):167-74. Zwienenberg M, Muizelaar JP. PMID: 11320595.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    53. Lack of effect of induction of hypothermia after acute brain injury. N Engl J Med. 2001 Feb 22; 344(8):556-63. Clifton GL, Miller ER, Choi SC, Levin HS, McCauley S, Smith KR, Muizelaar JP, Wagner FC, Marion DW, Luerssen TG, Chesnut RM, Schwartz M. PMID: 11207351.
      View in: PubMed   Mentions: 219     Fields:    Translation:HumansCTClinical Trials
    54. Balloon prophylaxis of aneurysmal vasospasm. Acta Neurochir Suppl. 2001; 77:185-90. Muizelaar JP, Madden LK. PMID: 11563283.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    55. Improvement in mitochondrial dysfunction as a new surrogate efficiency measure for preclinical trials: dose-response and time-window profiles for administration of the calcium channel blocker Ziconotide in experimental brain injury. J Neurosurg. 2000 Nov; 93(5):829-34. Verweij BH, Muizelaar JP, Vinas FC, Peterson PL, Xiong Y, Lee CP. PMID: 11059665.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    56. Neurobehavioral protection by the neuronal calcium channel blocker ziconotide in a model of traumatic diffuse brain injury in rats. J Neurosurg. 2000 Nov; 93(5):821-8. Berman RF, Verweij BH, Muizelaar JP. PMID: 11059664.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    57. Impaired cerebral mitochondrial function after traumatic brain injury in humans. J Neurosurg. 2000 Nov; 93(5):815-20. Verweij BH, Muizelaar JP, Vinas FC, Peterson PL, Xiong Y, Lee CP. PMID: 11059663.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansCells
    58. Subarachnoid haemorrhage following rupture of an ophthalmic artery aneurysm presenting as traumatic brain injury. Clin Neurol Neurosurg. 2000 Mar; 102(1):29-32. Vos PE, Zwienenberg M, O'Hannian KL, Muizelaar JP. PMID: 10717400.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    59. Transluminal balloon angioplasty for prevention of vasospasm. J Neurosurg. 2000 Feb; 92(2):369-71. Cloft HJ, Shengelaia G. PMID: 10659035.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    60. Acute quadriplegia myopathy in the intensive care unit: time to look at a mechanistic approach. Crit Care Med. 2000 Jan; 28(1):260-1. Zwienenberg M, Muizelaar JP. PMID: 10667539.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    61. Severe pediatric head injury: the role of hyperemia revisited. J Neurotrauma. 1999 Oct; 16(10):937-43. Zwienenberg M, Muizelaar JP. PMID: 10547102.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    62. Current status of neuroprotection trials for traumatic brain injury: lessons from animal models and clinical studies. Neurosurgery. 1999 Aug; 45(2):207-17; discussion 217-20. Bullock MR, Lyeth BG, Muizelaar JP. PMID: 10449064.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimals
    63. The prophylactic use of transluminal balloon angioplasty in patients with Fisher Grade 3 subarachnoid hemorrhage: a pilot study. J Neurosurg. 1999 Jul; 91(1):51-8. Muizelaar JP, Zwienenberg M, Rudisill NA, Hecht ST. PMID: 10389880.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    64. [Roaming through methodology. XII. Pragmatic and pathophysiologic trials: a question of goal formulation]. Ned Tijdschr Geneeskd. 1999 May 15; 143(20):1063. Muizelaar JP. PMID: 10368734.
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    65. Brain stem blood flow, pupillary response, and outcome in patients with severe head injuries. Neurosurgery. 1999 May; 44(5):941-8. Ritter AM, Muizelaar JP, Barnes T, Choi S, Fatouros P, Ward J, Bullock MR. PMID: 10232526.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    66. A cohort study of the safety and feasibility of intraventricular urokinase for nonaneurysmal spontaneous intraventricular hemorrhage. Stroke. 1998 Aug; 29(8):1573-9. Coplin WM, Vinas FC, Agris JM, Buciuc R, Michael DB, Diaz FG, Muizelaar JP. PMID: 9707195.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCTClinical Trials
    67. Mitochondrial dysfunction after experimental traumatic brain injury: combined efficacy of SNX-111 and U-101033E. J Neurotrauma. 1998 Jul; 15(7):531-44. Xiong Y, Peterson PL, Verweij BH, Vinas FC, Muizelaar JP, Lee CP. PMID: 9674556.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    68. Regional cerebral blood volume after severe head injury in patients with regional cerebral ischemia. Neurosurgery. 1998 Jun; 42(6):1276-80; discussion 1280-1. Schröder ML, Muizelaar JP, Fatouros PP, Kuta AJ, Choi SC. PMID: 9632185.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    69. Disruption of MAP-2 immunostaining in rat hippocampus after traumatic brain injury. J Neurotrauma. 1998 May; 15(5):349-63. Folkerts MM, Berman RF, Muizelaar JP, Rafols JA. PMID: 9605349.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    70. The pathophysiology of brain injury: understanding innovative drug therapies. J Head Trauma Rehabil. 1998 Feb; 13(1):1-10. Zafonte R, Muizelaar JP, Peterson PL. PMID: 9565700.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    71. Early cerebral blood volume after severe traumatic brain injury in patients with early cerebral ischemia. Acta Neurochir Suppl. 1998; 71:127-30. Schröder ML, Muizelaar JP, Fatouros P, Kuta AJ, Choi SC. PMID: 9779164.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    72. Pathogenesis of traumatic brain swelling: role of cerebral blood volume. Acta Neurochir Suppl. 1998; 71:272-5. Bouma GJ, Muizelaar JP, Fatouros P. PMID: 9779205.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    73. Amelioration of mitochondrial function by a novel antioxidant U-101033E following traumatic brain injury in rats. J Neurotrauma. 1997 Dec; 14(12):907-17. Xiong Y, Peterson PL, Muizelaar JP, Lee CP. PMID: 9475372.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    74. A new method for quantitative regional cerebral blood volume measurements using computed tomography. Stroke. 1997 Oct; 28(10):1998-2005. Muizelaar JP, Fatouros PP, Schröder ML. PMID: 9341710.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    75. Mitochondrial dysfunction after experimental and human brain injury and its possible reversal with a selective N-type calcium channel antagonist (SNX-111). Neurol Res. 1997 Jun; 19(3):334-9. Verweij BH, Muizelaar JP, Vinas FC, Peterson PL, Xiong Y, Lee CP. PMID: 9192388.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    76. Correlation between transcranial Doppler ultrasonography and regional cerebral blood flow in experimental intracranial hypertension. Stroke. 1997 Mar; 28(3):603-7; discussion 608. Nagai H, Moritake K, Takaya M. PMID: 9056619.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    77. Complex regional pain syndrome (reflex sympathetic dystrophy and causalgia): management with the calcium channel blocker nifedipine and/or the alpha-sympathetic blocker phenoxybenzamine in 59 patients. Clin Neurol Neurosurg. 1997 Feb; 99(1):26-30. Muizelaar JP, Kleyer M, Hertogs IA, DeLange DC. PMID: 9107464.
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    78. Mitochondrial dysfunction and calcium perturbation induced by traumatic brain injury. J Neurotrauma. 1997 Jan; 14(1):23-34. Xiong Y, Gu Q, Peterson PL, Muizelaar JP, Lee CP. PMID: 9048308.
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    79. Effects of pegorgotein on neurologic outcome of patients with severe head injury. A multicenter, randomized controlled trial. JAMA. 1996 Aug 21; 276(7):538-43. Young B, Runge JW, Waxman KS, Harrington T, Wilberger J, Muizelaar JP, Boddy A, Kupiec JW. PMID: 8709402.
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    80. Thresholds for cerebral ischemia after severe head injury: relationship with late CT findings and outcome. J Neurotrauma. 1996 Jan; 13(1):17-23. Schröder ML, Muizelaar JP, Kuta AJ, Choi SC. PMID: 8714859.
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    81. Avoiding secondary brain injury after severe head trauma: monitoring and management. J Craniomaxillofac Trauma. 1996; 2(3):8-17. Verweij BH, Muizelaar JP. PMID: 11951458.
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    82. PEG-SOD after head injury. J Neurosurg. 1995 Nov; 83(5):942. Muizelaar JP, Kupiec JW, Rapp LA. PMID: 7472573.
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    83. Cerebral blood flow in severe clinical head injury. New Horiz. 1995 Aug; 3(3):384-94. Bouma GJ, Muizelaar JP. PMID: 7496746.
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    84. Focal ischemia due to traumatic contusions documented by stable xenon-CT and ultrastructural studies. J Neurosurg. 1995 Jun; 82(6):966-71. Schröder ML, Muizelaar JP, Bullock MR, Salvant JB, Povlishock JT. PMID: 7760199.
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    85. Medical complications of aneurysmal subarachnoid hemorrhage: a report of the multicenter, cooperative aneurysm study. Participants of the Multicenter Cooperative Aneurysm Study. Crit Care Med. 1995 Jun; 23(6):1007-17. Solenski NJ, Haley EC, Kassell NF, Kongable G, Germanson T, Truskowski L, Torner JC. PMID: 7774210.
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    86. Coagulopathy with the use of hetastarch in the treatment of vasospasm. J Neurosurg. 1995 Jan; 82(1):44-7. Trumble ER, Muizelaar JP, Myseros JS, Choi SC, Warren BB. PMID: 7529301.
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    87. Overview of monitoring of cerebral blood flow and metabolism after severe head injury. Can J Neurol Sci. 1994 May; 21(2):S6-11. Muizelaar JP, Schröder ML. PMID: 8087732.
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    88. Documented reversal of global ischemia immediately after removal of an acute subdural hematoma. Report of two cases. J Neurosurg. 1994 Feb; 80(2):324-7. Schröder ML, Muizelaar JP, Kuta AJ. PMID: 8283273.
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    89. Clinical trials with Dismutec (pegorgotein; polyethylene glycol-conjugated superoxide dismutase; PEG-SOD) in the treatment of severe closed head injury. Adv Exp Med Biol. 1994; 366:389-400. Muizelaar JP. PMID: 7771267.
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    90. Changes in cerebral blood flow and metabolism related to the presence of subdural hematoma. Neurosurgery. 1993 Sep; 33(3):387-93; discussion 393. Salvant JB, Muizelaar JP. PMID: 8413868.
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    91. Cerebral ischemia-reperfusion injury after severe head injury and its possible treatment with polyethyleneglycol-superoxide dismutase. Ann Emerg Med. 1993 Jun; 22(6):1014-21. Muizelaar JP. PMID: 8503521.
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    92. Improving the outcome of severe head injury with the oxygen radical scavenger polyethylene glycol-conjugated superoxide dismutase: a phase II trial. J Neurosurg. 1993 Mar; 78(3):375-82. Muizelaar JP, Marmarou A, Young HF, Choi SC, Wolf A, Schneider RL, Kontos HA. PMID: 8433137.
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    93. Brain ischemia in head injury. J Neurosurg. 1993 Mar; 78(3):522-3. Cruz J. PMID: 8433161.
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    94. Middle cerebral artery occlusion without craniectomy in rats. Which method works best? Stroke. 1993 Feb; 24(2):294-7; discussion 297-8. Laing RJ, Jakubowski J, Laing RW. PMID: 8421831.
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    95. Oxygen content, blood viscosity, and cerebral blood flow. Stroke. 1993 Feb; 24(2):329-30. Wade JP. PMID: 8489578.
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    96. Monitoring of regional cerebral blood flow (CBF) in acute head injury by thermal diffusion. Acta Neurochir Suppl (Wien). 1993; 59:47-9. Schröder ML, Muizelaar JP. PMID: 8310862.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    97. Evaluation of regional cerebral blood flow in acute head injury by stable xenon-enhanced computerized tomography. Acta Neurochir Suppl (Wien). 1993; 59:34-40. Bouma GJ, Muizelaar JP. PMID: 8310860.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    98. Desmoplastic cerebral astrocytoma of infancy. A case report with immunohistochemical, ultrastructural and proliferation studies. Acta Neuropathol. 1993; 86(6):666-70. Aydin F, Ghatak NR, Salvant J, Muizelaar P. PMID: 7906073.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    99. Effect of THAM upon outcome in severe head injury: a randomized prospective clinical trial. J Neurosurg. 1993 Jan; 78(1):54-9. Wolf AL, Levi L, Marmarou A, Ward JD, Muizelaar PJ, Choi S, Young H, Rigamonti D, Robinson WL. PMID: 8416243.
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    100. Traumatic brain tissue acidosis: experimental and clinical studies. Acta Neurochir Suppl (Wien). 1993; 57:160-4. Marmarou A, Holdaway R, Ward JD, Yoshida K, Choi SC, Muizelaar JP, Young HF. PMID: 8421951.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCTClinical Trials
    101. A temporal transsylvian approach to anterior circulation aneurysms. Neurosurgery. 1992 Dec; 31(6):1137. Muizelaar JP. PMID: 1470331.
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    102. Ultra-early evaluation of regional cerebral blood flow in severely head-injured patients using xenon-enhanced computerized tomography. J Neurosurg. 1992 Sep; 77(3):360-8. Bouma GJ, Muizelaar JP, Stringer WA, Choi SC, Fatouros P, Young HF. PMID: 1506882.
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    103. Blood pressure and intracranial pressure-volume dynamics in severe head injury: relationship with cerebral blood flow. J Neurosurg. 1992 Jul; 77(1):15-9. Bouma GJ, Muizelaar JP, Bandoh K, Marmarou A. PMID: 1607958.
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    104. Effect of hematocrit variations on cerebral blood flow and basilar artery diameter in vivo. Am J Physiol. 1992 Apr; 262(4 Pt 2):H949-54. Muizelaar JP, Bouma GJ, Levasseur JE, Kontos HA. PMID: 1566914.
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    105. Prediction tree for severely head-injured patients. J Neurosurg. 1992 Mar; 76(3):561-2. Levy DE. PMID: 1738045.
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    106. Cerebral blood flow, cerebral blood volume, and cerebrovascular reactivity after severe head injury. J Neurotrauma. 1992 Mar; 9 Suppl 1:S333-48. Bouma GJ, Muizelaar JP. PMID: 1588625.
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    107. Adverse effects of prolonged hyperventilation in patients with severe head injury: a randomized clinical trial. J Neurosurg. 1991 Nov; 75(5):731-9. Muizelaar JP, Marmarou A, Ward JD, Kontos HA, Choi SC, Becker DP, Gruemer H, Young HF. PMID: 1919695.
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    108. Cerebral circulation and metabolism after severe traumatic brain injury: the elusive role of ischemia. J Neurosurg. 1991 Nov; 75(5):685-93. Bouma GJ, Muizelaar JP, Choi SC, Newlon PG, Young HF. PMID: 1919689.
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    109. Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. N Engl J Med. 1991 08 15; 325(7):445-53. North American Symptomatic Carotid Endarterectomy Trial Collaborators, Barnett HJM, Taylor DW, Haynes RB, Sackett DL, Peerless SJ, Ferguson GG, Fox AJ, Rankin RN, Hachinski VC, Wiebers DO, Eliasziw M. PMID: 1852179.
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    110. Prediction tree for severely head-injured patients. J Neurosurg. 1991 Aug; 75(2):251-5. Choi SC, Muizelaar JP, Barnes TY, Marmarou A, Brooks DM, Young HF. PMID: 2072162.
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    111. Description of a closed window technique for in vivo study of the feline basilar artery. Stroke. 1991 Apr; 22(4):522-6. Bouma GJ, Levasseur JE, Muizelaar JP, Wiatt RG, Kontos HA. PMID: 1902601.
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    112. Tumoral thrombosis of cerebral venous sinuses: preoperative diagnosis using magnetic resonance phase imaging. Surg Neurol. 1991 Mar; 35(3):189-95. Nadel L, Braun IF, Muizelaar JP, Laine FJ. PMID: 1996447.
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    113. Relationship between cardiac output and cerebral blood flow in patients with intact and with impaired autoregulation. J Neurosurg. 1990 Sep; 73(3):368-74. Bouma GJ, Muizelaar JP. PMID: 2384774.
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    114. The use of electroencephalography and brain protection during operation for basilar aneurysms. Neurosurgery. 1989 Dec; 25(6):899-903. Muizelaar JP. PMID: 2601820.
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    115. Acute lumbosacral epidural abscess after percutaneous transluminal angioplasty. Am J Med. 1989 Oct; 87(4):478. Wayne DA, Muizelaar PJ. PMID: 2529762.
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    116. Cerebral blood flow and metabolism in severely head-injured children. Part 2: Autoregulation. J Neurosurg. 1989 Jul; 71(1):72-6. Muizelaar JP, Ward JD, Marmarou A, Newlon PG, Wachi A. PMID: 2738644.
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    117. Cerebral blood flow and metabolism in severely head-injured children. Part 1: Relationship with GCS score, outcome, ICP, and PVI. J Neurosurg. 1989 Jul; 71(1):63-71. Muizelaar JP, Marmarou A, DeSalles AA, Ward JD, Zimmerman RS, Li Z, Choi SC, Young HF. PMID: 2738643.
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    118. Pial arteriolar vessel diameter and CO2 reactivity during prolonged hyperventilation in the rabbit. J Neurosurg. 1988 Dec; 69(6):923-7. Muizelaar JP, van der Poel HG, Li ZC, Kontos HA, Levasseur JE. PMID: 3142972.
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    119. Early operation of ruptured basilar artery aneurysm associated with bilateral carotid occlusion (moyamoya disease). Clin Neurol Neurosurg. 1988; 90(4):349-55. Muizelaar JP. PMID: 3233861.
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    120. Outcome of aneurysmal subarachnoid hemorrhage in patients 66 years of age and older. Clin Neurol Neurosurg. 1988; 90(3):203-7. Muizelaar JP, Vermeulen M, van Crevel H, Hijdra A, van Gijn J, Teasdale GM, Lindsay KW, Murray GD. PMID: 3197345.
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    121. Pressure-volume index in head injury. J Neurosurg. 1987 Dec; 67(6):832-40. Maset AL, Marmarou A, Ward JD, Choi S, Lutz HA, Brooks D, Moulton RJ, DeSalles A, Muizelaar JP, Turner H, et al. PMID: 3681422.
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    122. [Treatment of long-lasting post-spinal puncture headache]. Ned Tijdschr Geneeskd. 1987 Nov 07; 131(45):2003-5. van Crevel H, Muizelaar JP, van Ouwerkerk RC. PMID: 3683622.
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    123. Hyperglycemia, cerebrospinal fluid lactic acidosis, and cerebral blood flow in severely head-injured patients. Neurosurgery. 1987 Jul; 21(1):45-50. De Salles AA, Muizelaar JP, Young HF. PMID: 3614603.
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    124. Contribution of CSF and vascular factors to elevation of ICP in severely head-injured patients. J Neurosurg. 1987 Jun; 66(6):883-90. Marmarou A, Maset AL, Ward JD, Choi S, Brooks D, Lutz HA, Moulton RJ, Muizelaar JP, DeSalles A, Young HF. PMID: 3572518.
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    125. CSF brain creatine kinase levels and lactic acidosis in severe head injury. J Neurosurg. 1986 Nov; 65(5):625-9. Rabow L, DeSalles AF, Becker DP, Yang M, Kontos HA, Ward JD, Moulton RJ, Clifton G, Gruemer HD, Muizelaar JP, et al. PMID: 3772449.
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    126. Induced hypertension for the treatment of cerebral ischemia after subarachnoid hemorrhage. Direct effect on cerebral blood flow. Surg Neurol. 1986 Apr; 25(4):317-25. Muizelaar JP, Becker DP. PMID: 3952624.
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    127. EC-IC bypass and refractory vasospasm. Neurosurgery. 1986 Mar; 18(3):389. Muizelaar JP. PMID: 3703206.
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    128. Cerebral blood flow is regulated by changes in blood pressure and in blood viscosity alike. Stroke. 1986 Jan-Feb; 17(1):44-8. Muizelaar JP, Wei EP, Kontos HA, Becker DP. PMID: 3080824.
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    129. Improving outcome of aneurysmal subarachnoid hemorrhage. Va Med. 1985 Jun; 112(6):374-9. Muizelaar JP, Becker DP. PMID: 4024711.
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    130. Recovery from aphasia following extracranial-intracranial bypass surgery: case report. J Clin Exp Neuropsychol. 1985 Jun; 7(3):224-30. Hart RP, Rosner MJ, Muizelaar P. PMID: 2581990.
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    131. Nimodipine treatment of ischemic neurological deficits due to cerebral vasospasm after subarachnoid hemorrhage. Clinical results of a multicenter study. Neurochirurgia (Stuttg). 1985 May; 28 Suppl 1:114-7. Koos WT, Perneczky A, Auer LM, Böker DK, Gaab M, Jaksche H, Kostron H, Meinig G, Muizelaar JP, van der Werf AJ, et al. PMID: 4010866.
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    132. Effect of mannitol on ICP and CBF and correlation with pressure autoregulation in severely head-injured patients. J Neurosurg. 1984 Oct; 61(4):700-6. Muizelaar JP, Lutz HA, Becker DP. PMID: 6432972.
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    133. Antifibrinolytic treatment in subarachnoid hemorrhage. N Engl J Med. 1984 Aug 16; 311(7):432-7. Vermeulen M, Lindsay KW, Murray GD, Cheah F, Hijdra A, Muizelaar JP, Schannong M, Teasdale GM, van Crevel H, van Gijn J. PMID: 6379455.
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    134. Mannitol causes compensatory cerebral vasoconstriction and vasodilation in response to blood viscosity changes. J Neurosurg. 1983 Nov; 59(5):822-8. Muizelaar JP, Wei EP, Kontos HA, Becker DP. PMID: 6413661.
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    135. Do antifibrinolytic agents prevent rebleeding after rupture of a cerebral aneurysm? A review. Clin Neurol Neurosurg. 1980; 82(1):25-30. Vermeulen M, Muizelaar JP. PMID: 6257437.
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    136. Spontaneous neuronal activity in experimental atherosclerosis. Act Nerv Super (Praha). 1977 Jul; 19 Suppl 2:348-9. van Emde Boas W, van Cranenburgh B, Schadé JP, Muizelaar JP. PMID: 551652.
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    137. Tension pneumocephalus following insertion of ventriculoatrial shunt after severe head trauma. Case report. Clin Neurol Neurosurg. 1977; 80(1):57-61. Muizelaar JP, Walder HA. PMID: 201418.
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    138. [Obstetrical brachial plexus injuries. A study on perinatal morbidity]. Ned Tijdschr Geneeskd. 1976 Oct 02; 120(40):1666-72. Treffers PE, Muizelaar JP, Fleury P. PMID: 1086437.
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    139. Probenecid: dosage, levels in plasma and cerebrospinal fluid (CSF) and influence upon CSF levels of homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) in the rabbit. Psychopharmacologia. 1975 Sep 17; 43(3):223-7. Muizelaar JP, Oberink JI. PMID: 1187954.
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    140. A device for the maintenance of a constant body temperature, with some special features. Electroencephalogr Clin Neurophysiol. 1975 Aug; 39(2):193-4. Overdijk J, Muizelaar JP. PMID: 50216.
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    141. Neuronal firing in experimental hypercholesterolemia in rabbits. Arch Int Physiol Biochim. 1974; 82(2):391-5. Muizelaar JP. PMID: 4135891.
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