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Nathan Kuppermann

Title(s)Professor, Emergency Medicine
SchoolUniversity of California, Davis
Phone916-734-1535
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Kuppermann N, Mahajan P, Ramilo O. Efficacy of a Clinical Prediction Rule to Identify Febrile Young Infants at Low Risk for Serious Bacterial Infections-Reply. JAMA Pediatr. 2019 Aug 19. PMID: 31424528.
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    2. Trappey AF, Thompson KM, Kuppermann N, Stephenson JT, Nuno MA, Hewes HA, Meyers SR, Stanley RM, Galante JM, Nishijima DK. Development of Transfusion Guidelines for Injured Children Using a Modified Delphi Consensus Process. J Trauma Acute Care Surg. 2019 Jul 09. PMID: 31299040.
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    3. Powers PE, Shore KK, Perez S, Ritley D, Kuppermann N, Holmes JF, Tzimenatos LS, Shawargga H, Nishijima DK. Public Deliberation as a Novel Method for an Exception from Informed Consent Community Consultation. Acad Emerg Med. 2019 Jul 04. PMID: 31271691.
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    4. Leonard JC, Browne LR, Ahmad FA, Schwartz H, Wallendorf M, Leonard JR, Lerner EB, Kuppermann N. Cervical Spine Injury Risk Factors in Children With Blunt Trauma. Pediatrics. 2019 Jul; 144(1). PMID: 31221898.
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    5. Balamuth F, Kittick M, McBride P, Woodford AL, Vestal N, Casper TC, Metheney M, Smith K, Atkin NJ, Baren J, Dean JM, Kuppermann N, Weiss SL. PRagMatic Pediatric Trial of Balanced versus nOrmaL Saline FlUid in Sepsis: the PRoMPT BOLUS Randomized Controlled Trial Pilot Feasibility Study. Acad Emerg Med. 2019 Jun 10. PMID: 31183919.
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    6. Jamal A, Finkelstein Y, Kuppermann N, Freedman SB, Florin TA, Babl FE, Dalziel SR, Zemek R, Plint AC, Steele DW, Schnadower D, Johnson DW, Stephens D, Kharbanda A, Roland D, Lyttle MD, Macias CG, Fernandes RM, Benito J, Schuh S. Pharmacotherapy in bronchiolitis at discharge from emergency departments within the Pediatric Emergency Research Networks: a retrospective analysis. Lancet Child Adolesc Health. 2019 Aug; 3(8):539-547. PMID: 31182422.
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    7. Kuppermann N, Mahajan P, Ramilo O. Prediction Models for Febrile Infants: Time for a Unified Field Theory. Pediatrics. 2019 Jul; 144(1). PMID: 31167937.
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    8. Florin TA, Byczkowski T, Gerber JS, Ruddy R, Kuppermann N. Diagnostic Testing and Antibiotic Use in Young Children With Community-Acquired Pneumonia in the United States, 2008-2015. J Pediatric Infect Dis Soc. 2019 May 20. PMID: 31107533.
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    9. Rogers AJ, Kuppermann N, Anders J, Roosevelt G, Hoyle JD, Ruddy RM, Bennett JE, Borgialli DA, Dayan PS, Powell EC, Casper TC, Ramilo O, Mahajan P. Practice Variation in the Evaluation and Disposition of Febrile Infants =60 Days of Age. J Emerg Med. 2019 Jun; 56(6):583-591. PMID: 31014970.
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    10. Kuppermann N, Dayan PS, Levine DA, Vitale M, Tzimenatos L, Tunik MG, Saunders M, Ruddy RM, Roosevelt G, Rogers AJ, Powell EC, Nigrovic LE, Muenzer J, Linakis JG, Grisanti K, Jaffe DM, Hoyle JD, Greenberg R, Gattu R, Cruz AT, Crain EF, Cohen DM, Brayer A, Borgialli D, Bonsu B, Browne L, Blumberg S, Bennett JE, Atabaki SM, Anders J, Alpern ER, Miller B, Casper TC, Dean JM, Ramilo O, Mahajan P. A Clinical Prediction Rule to Identify Febrile Infants 60 Days and Younger at Low Risk for Serious Bacterial Infections. JAMA Pediatr. 2019 Feb 18. PMID: 30776077.
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    11. Nishijima DK, Kuppermann N, Roberts I, VanBuren JM, Tancredi DJ. The Effect of Tranexamic Acid on Functional Outcomes: An Exploratory Analysis of the CRASH-2 Randomized Controlled Trial. Ann Emerg Med. 2019 Jul; 74(1):79-87. PMID: 30642657.
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    12. Mintegi S, Azkunaga B, Prego J, Qureshi N, Dalziel SR, Arana-Arri E, Acedo Y, Martinez-Indart L, Urkaregi A, Salmon N, Benito J, Kuppermann N. International Epidemiological Differences in Acute Poisonings in Pediatric Emergency Departments. Pediatr Emerg Care. 2019 Jan; 35(1):50-57. PMID: 28121975.
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    13. Ballard DW, Kuppermann N, Vinson DR, Tham E, Hoffman JM, Swietlik M, Deakyne Davies SJ, Alessandrini EA, Tzimenatos L, Bajaj L, Mark DG, Offerman SR, Chettipally UK, Paterno MD, Schaeffer MH, Richards R, Casper TC, Goldberg HS, Grundmeier RW, Dayan PS. Implementation of a Clinical Decision Support System for Children With Minor Blunt Head Trauma Who Are at Nonnegligible Risk for Traumatic Brain Injuries. Ann Emerg Med. 2019 May; 73(5):440-451. PMID: 30583957.
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    14. Rees CA, Cruz AT, Freedman SB, Mahajan P, Uspal NG, Okada P, Aronson PL, Thompson AD, Ishimine PT, Schmidt SM, Kuppermann N, Nigrovic LE. Application of the Bacterial Meningitis Score for Infants Aged 0 to 60 Days. J Pediatric Infect Dis Soc. 2018 Dec 10. PMID: 30535235.
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    15. Stoner MJ, Mahajan P, Bressan S, Lam SHF, Chumpitazi CE, Kornblith AE, Linakis SW, Roland D, Freedman SB, Nigrovic LE, Denninghoff K, Ishimine P, Kuppermann N. Pediatric Emergency Care Research Networks: A Research Agenda. Acad Emerg Med. 2018 Dec; 25(12):1336-1344. PMID: 30393902.
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    16. Glaser N, Kuppermann N. Fluid treatment for children with diabetic ketoacidosis: How do the results of the pediatric emergency care applied research network Fluid Therapies Under Investigation in Diabetic Ketoacidosis (FLUID) Trial change our perspective? Pediatr Diabetes. 2019 02; 20(1):10-14. PMID: 30417497.
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    17. Mahajan P, Visclosky T, Bhoi S, Galwankar S, Kuppermann N, Neumar R. The importance of developing global emergency medicine research network. Am J Emerg Med. 2019 Apr; 37(4):744-745. PMID: 30527916.
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    18. Nishijima DK, VanBuren J, Hewes HA, Myers SR, Stanley RM, Adelson PD, Barnhard SE, Bobinski M, Ghetti S, Holmes JF, Roberts I, Schalick WO, Tran NK, Tzimenatos LS, Michael Dean J, Kuppermann N. Traumatic injury clinical trial evaluating tranexamic acid in children (TIC-TOC): study protocol for a pilot randomized controlled trial. Trials. 2018 Oct 30; 19(1):593. PMID: 30376893.
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    19. Ramgopal S, Janofsky S, Zuckerbraun NS, Ramilo O, Mahajan P, Kuppermann N, Vitale MA. Risk of Serious Bacterial Infection in Infants Aged =60 Days Presenting to Emergency Departments with a History of Fever Only. J Pediatr. 2019 01; 204:191-195. PMID: 30291019.
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    20. Kuppermann N, Glaser NS. Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis. N Engl J Med. 2018 09 20; 379(12):1183-1184. PMID: 30231223.
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    21. Hess EP, Homme JL, Kharbanda AB, Tzimenatos L, Louie JP, Cohen DM, Nigrovic LE, Westphal JJ, Shah ND, Inselman J, Ferrara MJ, Herrin J, Montori VM, Kuppermann N. Effect of the Head Computed Tomography Choice Decision Aid in Parents of Children With Minor Head Trauma: A Cluster Randomized Trial. JAMA Netw Open. 2018 Sep 07; 1(5):e182430. PMID: 30646167.
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    22. Mahajan P, Browne LR, Levine DA, Cohen DM, Gattu R, Linakis JG, Anders J, Borgialli D, Vitale M, Dayan PS, Casper TC, Ramilo O, Kuppermann N. Risk of Bacterial Coinfections in Febrile Infants 60 Days Old and Younger with Documented Viral Infections. J Pediatr. 2018 12; 203:86-91.e2. PMID: 30195552.
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    23. Masterson Creber RM, Dayan PS, Kuppermann N, Ballard DW, Tzimenatos L, Alessandrini E, Mistry RD, Hoffman J, Vinson DR, Bakken S. Applying the RE-AIM Framework for the Evaluation of a Clinical Decision Support Tool for Pediatric Head Trauma: A Mixed-Methods Study. Appl Clin Inform. 2018 Jul; 9(3):693-703. PMID: 30184559.
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    24. Vinson DR, Ballard DW, Dayan PS, Kuppermann N. Clinical Judgment and the Pediatric Emergency Care Applied Research Network Head Trauma Prediction Rules. Ann Emerg Med. 2018 Sep; 72(3):323-325. PMID: 30144870.
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    25. Blanchard A, Cabrera KI, Kuppermann N, Dayan PS. Acute Outcomes of Isolated Pneumocephali in Children After Minor Blunt Head Trauma. Pediatr Emerg Care. 2018 Sep; 34(9):656-660. PMID: 27741077.
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    26. Freire G, Kuppermann N, Zemek R, Plint AC, Babl FE, Dalziel SR, Freedman SB, Atenafu EG, Stephens D, Steele DW, Fernandes RM, Florin TA, Kharbanda A, Lyttle MD, Johnson DW, Schnadower D, Macias CG, Benito J, Schuh S. Predicting Escalated Care in Infants With Bronchiolitis. Pediatrics. 2018 09; 142(3). PMID: 30126934.
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    27. Newgard CD, Morris CD, Smith L, Cook JNB, Yealy DM, Collins S, Holmes JF, Kuppermann N, Richardson LD, Kimmel S, Becker LB, Scott JD, Lowe RA, Callaway CW, Gowen LK, Baren J, Storrow AB, Vasilevsky N, White M, Zell A. The First National Institutes of Health Institutional Training Program in Emergency Care Research: Productivity and Outcomes. Ann Emerg Med. 2018 Dec; 72(6):679-690. PMID: 30078658.
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    28. Holmes JF, Dayan PS, Kuppermann N. Multiple Pediatric Head Injury Decision Rules but What Should the Clinician Use? Acad Emerg Med. 2018 Jul; 25(7):811-814. PMID: 29971851.
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    29. Kuppermann N, Ghetti S, Schunk JE, Stoner MJ, Rewers A, McManemy JK, Myers SR, Nigrovic LE, Garro A, Brown KM, Quayle KS, Trainor JL, Tzimenatos L, Bennett JE, DePiero AD, Kwok MY, Perry CS, Olsen CS, Casper TC, Dean JM, Glaser NS. Clinical Trial of Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis. N Engl J Med. 2018 Jun 14; 378(24):2275-2287. PMID: 29897851.
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    30. Flynn-O'Brien KT, Kuppermann N, Holmes JF. Costal Margin Tenderness and the Risk for Intraabdominal Injuries in Children With Blunt Abdominal Trauma. Acad Emerg Med. 2018 Jul; 25(7):776-784. PMID: 29654622.
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    31. Johnson MA, Borgman MA, Cannon JW, Kuppermann N, Neff LP. Severely Elevated Blood Pressure and Early Mortality in Children with Traumatic Brain Injuries: The Neglected End of the Spectrum. West J Emerg Med. 2018 May; 19(3):452-459. PMID: 29760839.
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    32. Kharbanda AB, Vazquez-Benitez G, Ballard DW, Vinson DR, Chettipally UK, Kene MV, Dehmer SP, Bachur RG, Dayan PS, Kuppermann N, O'Connor PJ, Kharbanda EO. Development and Validation of a Novel Pediatric Appendicitis Risk Calculator (pARC). Pediatrics. 2018 04; 141(4). PMID: 29535251.
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    33. Parri N, Crosby BJ, Mills L, Soucy Z, Musolino AM, Da Dalt L, Cirilli A, Grisotto L, Kuppermann N. Point-of-Care Ultrasound for the Diagnosis of Skull Fractures in Children Younger Than Two Years of Age. J Pediatr. 2018 05; 196:230-236.e2. PMID: 29499992.
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    34. Tzimenatos L, Mahajan P, Dayan PS, Vitale M, Linakis JG, Blumberg S, Borgialli D, Ruddy RM, Van Buren J, Ramilo O, Kuppermann N. Accuracy of the Urinalysis for Urinary Tract Infections in Febrile Infants 60 Days and Younger. Pediatrics. 2018 02; 141(2). PMID: 29339564.
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    35. Marcin JP, Romano PS, Dayal P, Dharmar M, Chamberlain JM, Dudley N, Macias CG, Nigrovic LE, Powell EC, Rogers AJ, Sonnett M, Tzimenatos L, Alpern ER, Andrews-Dickert R, Borgialli DA, Sidney E, Charles Casper T, Michael Dean J, Kuppermann N. Patient-level Factors and the Quality of Care Delivered in Pediatric Emergency Departments. Acad Emerg Med. 2018 03; 25(3):301-309. PMID: 29150972.
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    36. Schuh S, Babl FE, Dalziel SR, Freedman SB, Macias CG, Stephens D, Steele DW, Fernandes RM, Zemek R, Plint AC, Florin TA, Lyttle MD, Johnson DW, Gouin S, Schnadower D, Klassen TP, Bajaj L, Benito J, Kharbanda A, Kuppermann N. Practice Variation in Acute Bronchiolitis: A Pediatric Emergency Research Networks Study. Pediatrics. 2017 Dec; 140(6). PMID: 29184035.
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    37. Goldberg LR, Kernie CG, Lillis K, Bennett J, Conners G, Macias CG, Callahan J, Akman C, Allen Hauser W, Kuppermann N, Dayan PS. Early Recurrence of First Unprovoked Seizures in Children. Acad Emerg Med. 2018 03; 25(3):275-282. PMID: 29105207.
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    38. Marcin JP, Romano PS, Dharmar M, Chamberlain JM, Dudley N, Macias CG, Nigrovic LE, Powell EC, Rogers AJ, Sonnett M, Tzimenatos L, Alpern ER, Andrews-Dickert R, Borgialli DA, Sidney E, Casper C, Dean JM, Kuppermann N. Implicit Review Instrument to Evaluate Quality of Care Delivered by Physicians to Children in Emergency Departments. Health Serv Res. 2018 06; 53(3):1316-1334. PMID: 29143331.
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    39. Cruz AT, Mahajan P, Bonsu BK, Bennett JE, Levine DA, Alpern ER, Nigrovic LE, Atabaki SM, Cohen DM, VanBuren JM, Ramilo O, Kuppermann N. Accuracy of Complete Blood Cell Counts to Identify Febrile Infants 60 Days or Younger With Invasive Bacterial Infections. JAMA Pediatr. 2017 11 06; 171(11):e172927. PMID: 28892537.
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    40. Browne LR, Schwartz H, Ahmad FA, Wallendorf M, Kuppermann N, Lerner EB, Leonard JC. Interobserver Agreement in Pediatric Cervical Spine Injury Assessment Between Prehospital and Emergency Department Providers. Acad Emerg Med. 2017 12; 24(12):1501-1510. PMID: 28921731.
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    41. Holmes JF, Kelley KM, Kuppermann N. The FAST Examination for Children With Abdominal Trauma-Reply. JAMA. 2017 10 10; 318(14):1394-1395. PMID: 29049581.
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    42. Powell EC, Mahajan PV, Roosevelt G, Hoyle JD, Gattu R, Cruz AT, Rogers AJ, Atabaki SM, Jaffe DM, Casper TC, Ramilo O, Kuppermann N. Epidemiology of Bacteremia in Febrile Infants Aged 60 Days and Younger. Ann Emerg Med. 2018 02; 71(2):211-216. PMID: 28988964.
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    43. Kuppermann N, Holmes JF, Dayan PS. Head injury decision rules in children. Lancet. 2017 09 23; 390(10101):1487-1488. PMID: 28952449.
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    44. Osmond MH. Head injury decision rules in children. Lancet. 2017 09 23; 390(10101):1487. PMID: 28952448.
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    45. Mintegi S, Dalziel SR, Azkunaga B, Prego J, Arana-Arri E, Acedo Y, Martinez-Indart L, Benito J, Kuppermann N. International Variability in Gastrointestinal Decontamination With Acute Poisonings. Pediatrics. 2017 08; 140(2). PMID: 28771410.
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    46. Holmes JF, Kelley KM, Wootton-Gorges SL, Utter GH, Abramson LP, Rose JS, Tancredi DJ, Kuppermann N. Effect of Abdominal Ultrasound on Clinical Care, Outcomes, and Resource Use Among Children With Blunt Torso Trauma: A Randomized Clinical Trial. JAMA. 2017 06 13; 317(22):2290-2296. PMID: 28609532.
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    47. Nigrovic LE, Mahajan PV, Blumberg SM, Browne LR, Linakis JG, Ruddy RM, Bennett JE, Rogers AJ, Tzimenatos L, Powell EC, Alpern ER, Casper TC, Ramilo O, Kuppermann N. The Yale Observation Scale Score and the Risk of Serious Bacterial Infections in Febrile Infants. Pediatrics. 2017 Jul; 140(1). PMID: 28759413.
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    48. Newgard CD, Fu R, Lerner EB, Daya M, Jui J, Wittwer L, Schmidt TA, Zive D, Bulger EM, Sahni R, Warden C, Kuppermann N. Role of Guideline Adherence in Improving Field Triage. Prehosp Emerg Care. 2017 Sep-Oct; 21(5):545-555. PMID: 28459301.
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    49. Dayal P, Horeczko T, Wraa C, Karsteadt L, Chapman W, Bruhnke L, Litman R, Ruttan T, Kuppermann N, Marcin J. Emergency Medical Services Utilization by Children. Pediatr Emerg Care. 2017 Apr 11. PMID: 28398935.
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    50. Badawy MK, Dayan PS, Tunik MG, Nadel FM, Lillis KA, Miskin M, Borgialli DA, Bachman MC, Atabaki SM, Hoyle JD, Holmes JF, Kuppermann N. Prevalence of Brain Injuries and Recurrence of Seizures in Children With Posttraumatic Seizures. Acad Emerg Med. 2017 05; 24(5):595-605. PMID: 28170143.
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    51. Dayan PS, Ballard DW, Tham E, Hoffman JM, Swietlik M, Deakyne SJ, Alessandrini EA, Tzimenatos L, Bajaj L, Vinson DR, Mark DG, Offerman SR, Chettipally UK, Paterno MD, Schaeffer MH, Wang J, Casper TC, Goldberg HS, Grundmeier RW, Kuppermann N. Use of Traumatic Brain Injury Prediction Rules With Clinical Decision Support. Pediatrics. 2017 Apr; 139(4). PMID: 28341799.
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    52. Ahmad FA, Schwartz H, Browne LR, Lassa-Claxton S, Wallendorf M, Brooke Lerner E, Kuppermann N, Leonard JC. Methods for Collecting Paired Observations From Emergency Medical Services and Emergency Department Providers for Pediatric Cervical Spine Injury Risk Factors. Acad Emerg Med. 2017 04; 24(4):432-441. PMID: 27976464.
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    53. Magana JN, Kuppermann N. The PECARN TBI Rules Do Not Apply to Abusive Head Trauma. Acad Emerg Med. 2017 03; 24(3):382-384. PMID: 28039943.
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    54. Ramilo O, Mejias A, Mahajan P, Kuppermann N. RNA signature test to distinguish bacterial from viral infection. J Pediatr. 2017 03; 182:401-404. PMID: 28237452.
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    55. Mistry RD, Newland JG, Gerber JS, Hersh AL, May L, Perman SM, Kuppermann N, Dayan PS. Current State of Antimicrobial Stewardship in Children's Hospital Emergency Departments. Infect Control Hosp Epidemiol. 2017 04; 38(4):469-475. PMID: 28173888.
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    56. Stanley RM, Johnson MD, Vance C, Bajaj L, Babcock L, Atabaki S, Thomas D, Simon HK, Cohen DM, Rubacalva D, David Adelson P, Bulloch B, Rogers AJ, Mahajan P, Baren J, Lee L, Hoyle J, Quayle K, Charles Casper T, Michael Dean J, Kuppermann N. Challenges Enrolling Children Into Traumatic Brain Injury Trials: An Observational Study. Acad Emerg Med. 2017 01; 24(1):31-39. PMID: 27618167.
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    57. Melnick ER, Probst MA, Schoenfeld E, Collins SP, Breslin M, Walsh C, Kuppermann N, Dunn P, Abella BS, Boatright D, Hess EP. Development and Testing of Shared Decision Making Interventions for Use in Emergency Care: A Research Agenda. Acad Emerg Med. 2016 12; 23(12):1346-1353. PMID: 27457137.
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    58. Glaser NS, Wootton-Gorges SL, Kim I, Tancredi DJ, Marcin JP, Muir A, Kuppermann N. Regional Brain Water Content and Distribution During Diabetic Ketoacidosis. J Pediatr. 2017 01; 180:170-176. PMID: 27745860.
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    59. Lubell TR, Schnadower D, Freedman SB, Macias CG, Agrawal D, Kuppermann N, Dayan PS. Comparison of Febrile Infants With Enterococcal and Gram-negative Urinary Tract Infections. Pediatr Infect Dis J. 2016 09; 35(9):943-8. PMID: 27195600.
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    60. Mahajan P, Kuppermann N, Mejias A, Suarez N, Chaussabel D, Casper TC, Smith B, Alpern ER, Anders J, Atabaki SM, Bennett JE, Blumberg S, Bonsu B, Borgialli D, Brayer A, Browne L, Cohen DM, Crain EF, Cruz AT, Dayan PS, Gattu R, Greenberg R, Hoyle JD, Jaffe DM, Levine DA, Lillis K, Linakis JG, Muenzer J, Nigrovic LE, Powell EC, Rogers AJ, Roosevelt G, Ruddy RM, Saunders M, Tunik MG, Tzimenatos L, Vitale M, Dean JM, Ramilo O. Association of RNA Biosignatures With Bacterial Infections in Febrile Infants Aged 60 Days or Younger. JAMA. 2016 Aug 23-30; 316(8):846-57. PMID: 27552618.
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    61. Borgialli DA, Mahajan P, Hoyle JD, Powell EC, Nadel FM, Tunik MG, Foerster A, Dong L, Miskin M, Dayan PS, Holmes JF, Kuppermann N. Performance of the Pediatric Glasgow Coma Scale Score in the Evaluation of Children With Blunt Head Trauma. Acad Emerg Med. 2016 08; 23(8):878-84. PMID: 27197686.
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    62. Tunik MG, Powell EC, Mahajan P, Schunk JE, Jacobs E, Miskin M, Zuspan SJ, Wootton-Gorges S, Atabaki SM, Hoyle JD, Holmes JF, Dayan PS, Kuppermann N. Clinical Presentations and Outcomes of Children With Basilar Skull Fractures After Blunt Head Trauma. Ann Emerg Med. 2016 10; 68(4):431-440.e1. PMID: 27471139.
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    63. Tham E, Swietlik M, Deakyne S, Hoffman JM, Grundmeier RW, Paterno MD, Rocha BH, Schaeffer MH, Pabbathi D, Alessandrini E, Ballard D, Goldberg HS, Kuppermann N, Dayan PS. Clinical Decision Support for a Multicenter Trial of Pediatric Head Trauma: Development, Implementation, and Lessons Learned. Appl Clin Inform. 2016; 7(2):534-42. PMID: 27437059.
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    64. Atabaki SM, Hoyle JD, Schunk JE, Monroe DJ, Alpern ER, Quayle KS, Glass TF, Badawy MK, Miskin M, Schalick WO, Dayan PS, Holmes JF, Kuppermann N. Comparison of Prediction Rules and Clinician Suspicion for Identifying Children With Clinically Important Brain Injuries After Blunt Head Trauma. Acad Emerg Med. 2016 05; 23(5):566-75. PMID: 26825755.
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    65. Natale JE, Joseph JG, Rogers AJ, Tunik M, Monroe D, Kerrey B, Bonsu BK, Cook LJ, Page K, Adelgais K, Quayle K, Kuppermann N, Holmes JF. Relationship of Physician-identified Patient Race and Ethnicity to Use of Computed Tomography in Pediatric Blunt Torso Trauma. Acad Emerg Med. 2016 05; 23(5):584-90. PMID: 26914184.
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    66. Nishijima DK, Monuteaux MC, Faraoni D, Goobie SM, Lee L, Galante J, Holmes JF, Kuppermann N. Tranexamic Acid Use in United States Children's Hospitals. J Emerg Med. 2016 Jun; 50(6):868-874.e1. PMID: 27017532; PMCID: PMC4912435 [Available on 06/01/17].
    67. Rogers AJ, Kuppermann N, Thelen AE, Stanley RM, Maher CO. Children With Arachnoid Cysts Who Sustain Blunt Head Trauma: Injury Mechanisms and Outcomes. Acad Emerg Med. 2016 Mar; 23(3):358-61. PMID: 26728086.
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    68. Garro A, Chodobski A, Szmydynger-Chodobska J, Shan R, Bialo SR, Bennett J, Quayle K, Rewers A, Schunk JE, Casper TC, Kuppermann N, Glaser N. Circulating matrix metalloproteinases in children with diabetic ketoacidosis. Pediatr Diabetes. 2017 03; 18(2):95-102. PMID: 26843101.
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    69. Kuppermann N, Mahajan P. Role of Serum Procalcitonin in Identifying Young Febrile Infants With Invasive Bacterial Infections: One Step Closer to the Holy Grail? JAMA Pediatr. 2016 Jan; 170(1):17-8. PMID: 26595161.
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    70. Goldberg HS, Paterno MD, Grundmeier RW, Rocha BH, Hoffman JM, Tham E, Swietlik M, Schaeffer MH, Pabbathi D, Deakyne SJ, Kuppermann N, Dayan PS. Use of a remote clinical decision support service for a multicenter trial to implement prediction rules for children with minor blunt head trauma. Int J Med Inform. 2016 Mar; 87:101-10. PMID: 26806717.
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    71. Nishijima DK, Holmes JF, Dayan PS, Kuppermann N. Association of a Guardian's Report of a Child Acting Abnormally With Traumatic Brain Injury After Minor Blunt Head Trauma. JAMA Pediatr. 2015 Dec; 169(12):1141-7. PMID: 26502172; PMCID: PMC4974948 [Available on 12/01/16].
    72. Rivara FP, Kuppermann N, Ellenbogen RG. Use of Clinical Prediction Rules for Guiding Use of Computed Tomography in Adults With Head Trauma. JAMA. 2015 Dec 22-29; 314(24):2629-31. PMID: 26717029.
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    73. Finnerty NM, Rodriguez RM, Carpenter CR, Sun BC, Theyyunni N, Ohle R, Dodd KW, Schoenfeld EM, Elm KD, Kline JA, Holmes JF, Kuppermann N. Clinical Decision Rules for Diagnostic Imaging in the Emergency Department: A Research Agenda. Acad Emerg Med. 2015 Dec; 22(12):1406-16. PMID: 26567885.
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    74. McCabe AM, Kuppermann N. Generation of Evidence and Translation Into Practice: Lessons Learned and Future Directions. Acad Emerg Med. 2015 Dec; 22(12):1372-9. PMID: 26568167.
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    75. Lichenstein R, Monroe D, Quayle KS, Miskin M, Cooper A, Gerardi MJ, Callahan JM, Dayan PS, Holmes JF, Kuppermann N. Television-Related Head Injuries in Children: A Secondary Analysis of a Large Cohort Study of Head-Injured Children in the Pediatric Emergency Care Applied Research Network. Pediatr Emerg Care. 2015 Nov 06. PMID: 26555312.
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    76. Goyal MK, Kuppermann N, Cleary SD, Teach SJ, Chamberlain JM. Racial Disparities in Pain Management of Children With Appendicitis in Emergency Departments. JAMA Pediatr. 2015 Nov; 169(11):996-1002. PMID: 26366984; PMCID: PMC4829078.
    77. Mahajan P, Kuppermann N, Tunik M, Yen K, Atabaki SM, Lee LK, Ellison AM, Bonsu BK, Olsen CS, Cook L, Kwok MY, Lillis K, Holmes JF. Comparison of Clinician Suspicion Versus a Clinical Prediction Rule in Identifying Children at Risk for Intra-abdominal Injuries After Blunt Torso Trauma. Acad Emerg Med. 2015 Sep; 22(9):1034-41. PMID: 26302354.
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    78. Deakyne SJ, Bajaj L, Hoffman J, Alessandrini E, Ballard DW, Norris R, Tzimenatos L, Swietlik M, Tham E, Grundmeier RW, Kuppermann N, Dayan PS. Development, Evaluation and Implementation of Chief Complaint Groupings to Activate Data Collection: A Multi-Center Study of Clinical Decision Support for Children with Head Trauma. Appl Clin Inform. 2015; 6(3):521-35. PMID: 26448796; PMCID: PMC4586340.
    79. Soucy ZP, Mills L, Rose JS, Kelley K, Ramirez F, Kuppermann N. Creation of a High-fidelity, Low-cost Pediatric Skull Fracture Ultrasound Phantom. J Ultrasound Med. 2015 Aug; 34(8):1473-8. PMID: 26206834.
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    80. Wisner DH, Kuppermann N, Cooper A, Menaker J, Ehrlich P, Kooistra J, Mahajan P, Lee L, Cook LJ, Yen K, Lillis K, Holmes JF. Management of children with solid organ injuries after blunt torso trauma. J Trauma Acute Care Surg. 2015 Aug; 79(2):206-14;quiz 332. PMID: 26218687.
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    81. Dayan PS, Lillis K, Bennett J, Conners G, Bailey P, Callahan J, Akman C, Feldstein N, Kriger J, Hauser WA, Kuppermann N. Prevalence of and Risk Factors for Intracranial Abnormalities in Unprovoked Seizures. Pediatrics. 2015 Aug; 136(2):e351-60. PMID: 26195538; PMCID: PMC4516940.
    82. Glass T, Ruddy RM, Alpern ER, Gorelick M, Callahan J, Lee L, Gerardi M, Melville K, Miskin M, Holmes JF, Kuppermann N. Traumatic brain injuries and computed tomography use in pediatric sports participants. Am J Emerg Med. 2015 Oct; 33(10):1458-64. PMID: 26256635.
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    83. Yang NH, Dharmar M, Yoo BK, Leigh JP, Kuppermann N, Romano PS, Nesbitt TS, Marcin JP. Economic Evaluation of Pediatric Telemedicine Consultations to Rural Emergency Departments. Med Decis Making. 2015 08; 35(6):773-83. PMID: 25952744.
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    84. Mistry RD, Dayan PS, Kuppermann N. The battle against antimicrobial resistance: time for the emergency department to join the fight. JAMA Pediatr. 2015 May; 169(5):421-2. PMID: 25799078.
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    85. Varano P, Cabrera KI, Kuppermann N, Dayan PS. Acute outcomes of isolated cerebral contusions in children with Glasgow Coma Scale scores of 14 to 15 after blunt head trauma. J Trauma Acute Care Surg. 2015 May; 78(5):1039-43. PMID: 25909428.
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    86. Ellison AM, Quayle KS, Bonsu B, Garcia M, Blumberg S, Rogers A, Wootton-Gorges SL, Kerrey BT, Cook LJ, Cooper A, Kuppermann N, Holmes JF. Use of Oral Contrast for Abdominal Computed Tomography in Children With Blunt Torso Trauma. Ann Emerg Med. 2015 Aug; 66(2):107-114.e4. PMID: 25794610.
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    87. Powell EC, Atabaki SM, Wootton-Gorges S, Wisner D, Mahajan P, Glass T, Miskin M, Stanley RM, Jacobs E, Dayan PS, Holmes JF, Kuppermann N. Isolated linear skull fractures in children with blunt head trauma. Pediatrics. 2015 Apr; 135(4):e851-7. PMID: 25780067.
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    88. Olsen CS, Kuppermann N, Jaffe DM, Brown K, Babcock L, Mahajan PV, Leonard JC. Interobserver agreement in retrospective chart reviews for factors associated with cervical spine injuries in children. Acad Emerg Med. 2015 Apr; 22(4):487-91. PMID: 25779540.
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    89. Leonard JC, Jaffe DM, Olsen CS, Kuppermann N. Age-related differences in factors associated with cervical spine injuries in children. Acad Emerg Med. 2015 Apr; 22(4):441-6. PMID: 25779934.
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    90. Yang NH, Dharmar M, Kuppermann N, Romano PS, Nesbitt TS, Hojman NM, Marcin JP. Appropriateness of disposition following telemedicine consultations in rural emergency departments. Pediatr Crit Care Med. 2015 Mar; 16(3):e59-64. PMID: 25607743.
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    91. Dayan PS, Holmes JF, Hoyle J, Atabaki S, Tunik MG, Lichenstein R, Miskin M, Kuppermann N. Headache in traumatic brain injuries from blunt head trauma. Pediatrics. 2015 Mar; 135(3):504-12. PMID: 25647678.
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    92. Tzimenatos L, Kim E, Kuppermann N. The Pediatric Emergency Care Applied Research Network: a history of multicenter collaboration in the United States. Pediatr Emerg Care. 2015 Jan; 31(1):70-6. PMID: 25560626.
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    93. Mahajan P, Kuppermann N, Suarez N, Mejias A, Casper C, Dean JM, Ramilo O. RNA transcriptional biosignature analysis for identifying febrile infants with serious bacterial infections in the emergency department: a feasibility study. Pediatr Emerg Care. 2015 Jan; 31(1):1-5. PMID: 25526020; PMCID: PMC4300534.
    94. Tzimenatos L, Kim E, Kuppermann N. The Pediatric Emergency Care Applied Research Network: a history of multicenter collaboration in the United States. Clin Exp Emerg Med. 2014 Dec; 1(2):78-86. PMID: 27752557.
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    95. Quayle KS, Powell EC, Mahajan P, Hoyle JD, Nadel FM, Badawy MK, Schunk JE, Stanley RM, Miskin M, Atabaki SM, Dayan PS, Holmes JF, Kuppermann N. Epidemiology of blunt head trauma in children in U.S. emergency departments. N Engl J Med. 2014 Nov 13; 371(20):1945-7. PMID: 25390756.
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    96. Nishijima DK, Yang Z, Urbich M, Holmes JF, Zwienenberg-Lee M, Melnikow J, Kuppermann N. Cost-effectiveness of the PECARN rules in children with minor head trauma. Ann Emerg Med. 2015 Jan; 65(1):72-80.e6. PMID: 25443992; PMCID: PMC4275394.
    97. Borgialli DA, Ellison AM, Ehrlich P, Bonsu B, Menaker J, Wisner DH, Atabaki S, Olsen CS, Sokolove PE, Lillis K, Kuppermann N, Holmes JF. Association between the seat belt sign and intra-abdominal injuries in children with blunt torso trauma in motor vehicle collisions. Acad Emerg Med. 2014 Nov; 21(11):1240-8. PMID: 25377401.
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    98. Stanley RM, Hoyle JD, Dayan PS, Atabaki S, Lee L, Lillis K, Gorelick MH, Holubkov R, Miskin M, Holmes JF, Dean JM, Kuppermann N. Emergency department practice variation in computed tomography use for children with minor blunt head trauma. J Pediatr. 2014 Dec; 165(6):1201-1206.e2. PMID: 25294604.
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    99. Adelgais KM, Kuppermann N, Kooistra J, Garcia M, Monroe DJ, Mahajan P, Menaker J, Ehrlich P, Atabaki S, Page K, Kwok M, Holmes JF. Accuracy of the abdominal examination for identifying children with blunt intra-abdominal injuries. J Pediatr. 2014 Dec; 165(6):1230-1235.e5. PMID: 25266346.
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    100. Schnadower D, Kuppermann N, Macias CG, Freedman SB, Agrawal D, Mao J, Dayan PS. Outpatient management of young febrile infants with urinary tract infections. Pediatr Emerg Care. 2014 Sep; 30(9):591-7. PMID: 25162689.
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    101. Lee LK, Monroe D, Bachman MC, Glass TF, Mahajan PV, Cooper A, Stanley RM, Miskin M, Dayan PS, Holmes JF, Kuppermann N. Isolated loss of consciousness in children with minor blunt head trauma. JAMA Pediatr. 2014 Sep; 168(9):837-43. PMID: 25003654.
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    102. Menaker J, Blumberg S, Wisner DH, Dayan PS, Tunik M, Garcia M, Mahajan P, Page K, Monroe D, Borgialli D, Kuppermann N, Holmes JF. Use of the focused assessment with sonography for trauma (FAST) examination and its impact on abdominal computed tomography use in hemodynamically stable children with blunt torso trauma. J Trauma Acute Care Surg. 2014 Sep; 77(3):427-32. PMID: 25159246.
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    103. Kwok MY, Yen K, Atabaki S, Adelgais K, Garcia M, Quayle K, Kooistra J, Bonsu BK, Page K, Borgialli D, Kuppermann N, Holmes JF. Sensitivity of plain pelvis radiography in children with blunt torso trauma. Ann Emerg Med. 2015 Jan; 65(1):63-71.e1. PMID: 25086474.
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    104. Hess EP, Wyatt KD, Kharbanda AB, Louie JP, Dayan PS, Tzimenatos L, Wootton-Gorges SL, Homme JL, Pencille R N L, LeBlanc A, Westphal JJ, Shepel K, Shah ND, Branda M, Herrin J, Montori VM, Kuppermann N. Effectiveness of the head CT choice decision aid in parents of children with minor head trauma: study protocol for a multicenter randomized trial. Trials. 2014 Jun 25; 15:253. PMID: 24965659; PMCID: PMC4081461.
    105. Kuppermann N, Natale JE, Nigrovic LE. Incorrect classification in articles about traumatic brain injuries in children with minor blunt head trauma. JAMA Pediatr. 2014 Jun; 168(6):585-6. PMID: 24840558.
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    106. Leonard JR, Jaffe DM, Kuppermann N, Olsen CS, Leonard JC. Cervical spine injury patterns in children. Pediatrics. 2014 May; 133(5):e1179-88. PMID: 24777222.
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    107. Lee LK, Rogers AJ, Ehrlich PF, Kwok M, Sokolove PE, Blumberg S, Kooistra J, Olsen CS, Wootton-Gorges S, Cooper A, Kuppermann N, Holmes JF. Occult pneumothoraces in children with blunt torso trauma. Acad Emerg Med. 2014 Apr; 21(4):440-8. PMID: 24730407.
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    108. Dayan PS, Holmes JF, Schutzman S, Schunk J, Lichenstein R, Foerster LA, Hoyle J, Atabaki S, Miskin M, Wisner D, Zuspan S, Kuppermann N. Risk of traumatic brain injuries in children younger than 24 months with isolated scalp hematomas. Ann Emerg Med. 2014 Aug; 64(2):153-62. PMID: 24635991.
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    109. Holmes JF, Kuppermann N. When do clinical decision rules improve patient care? Ann Emerg Med. 2014 Mar; 63(3):372-3. PMID: 24528950.
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    110. Dean D, Wetzel B, White N, Kuppermann N, Wang NE, Haukoos JS, Hsia RY, Mann NC, Barton ED, Newgard CD. From 9-1-1 call to death: evaluating traumatic deaths in seven regions for early recognition of high-risk patients. J Trauma Acute Care Surg. 2014 Mar; 76(3):846-53. PMID: 24553559.
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    111. Dayan PS, Holmes JF, Atabaki S, Hoyle J, Tunik MG, Lichenstein R, Alpern E, Miskin M, Kuppermann N. Association of traumatic brain injuries with vomiting in children with blunt head trauma. Ann Emerg Med. 2014 Jun; 63(6):657-65. PMID: 24559605.
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    112. Mahajan P, Grzybowski M, Chen X, Kannikeswaran N, Stanley R, Singal B, Hoyle J, Borgialli D, Duffy E, Kuppermann N. Procalcitonin as a marker of serious bacterial infections in febrile children younger than 3 years old. Acad Emerg Med. 2014 Feb; 21(2):171-9. PMID: 24673673.
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    113. Hoyle JD, Callahan JM, Badawy M, Powell E, Jacobs E, Gerardi M, Melville K, Miskin M, Atabaki SM, Dayan P, Holmes JF, Kuppermann N. Pharmacological sedation for cranial computed tomography in children after minor blunt head trauma. Pediatr Emerg Care. 2014 Jan; 30(1):1-7. PMID: 24365725.
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    114. Dharmar M, Kuppermann N, Romano PS, Yang NH, Nesbitt TS, Phan J, Nguyen C, Parsapour K, Marcin JP. Telemedicine consultations and medication errors in rural emergency departments. Pediatrics. 2013 Dec; 132(6):1090-7. PMID: 24276844.
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    115. Nishijima DK, Yang Z, Clark JA, Kuppermann N, Holmes JF, Melnikow J. A cost-effectiveness analysis comparing a clinical decision rule versus usual care to risk stratify children for intraabdominal injury after blunt torso trauma. Acad Emerg Med. 2013 Nov; 20(11):1131-8. PMID: 24238315; PMCID: PMC3930144.
    116. Mahajan P, Jaffe DM, Olsen CS, Leonard JR, Nigrovic LE, Rogers AJ, Kuppermann N, Leonard JC. Spinal cord injury without radiologic abnormality in children imaged with magnetic resonance imaging. J Trauma Acute Care Surg. 2013 Nov; 75(5):843-7. PMID: 24158204.
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    117. Horeczko T, Marcin JP, Kahn JM, Sapien RE. Urban and rural patterns in emergent pediatric transfer: a call for regionalization. J Rural Health. 2014; 30(3):252-8. PMID: 24164349.
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    118. Newgard CD, Kuppermann N, Holmes JF, Haukoos JS, Wetzel B, Hsia RY, Wang NE, Bulger EM, Staudenmayer K, Mann NC, Barton ED, Wintemute G. Gunshot injuries in children served by emergency services. Pediatrics. 2013 Nov; 132(5):862-70. PMID: 24127481; PMCID: PMC3813400.
    119. Mahajan P, Ramilo O, Kuppermann N. The future possibilities of diagnostic testing for the evaluation of febrile infants. JAMA Pediatr. 2013 Oct; 167(10):888-98. PMID: 23959454; PMCID: PMC4300530.
    120. Dharmar M, Romano PS, Kuppermann N, Nesbitt TS, Cole SL, Andrada ER, Vance C, Harvey DJ, Marcin JP. Impact of critical care telemedicine consultations on children in rural emergency departments. Crit Care Med. 2013 Oct; 41(10):2388-95. PMID: 23921273.
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    121. Holmes JF, Kuppermann N. In reply. Ann Emerg Med. 2013 Sep; 62(3):277-8. PMID: 23969130.
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    122. Izuhara K. Immune responses in the host-environment interface - understanding the mechanisms of allergic sensitization. Allergol Int. 2013 Sep; 62(3):277-278. PMID: 24137720.
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    123. Newgard CD, Mann NC, Hsia RY, Bulger EM, Ma OJ, Staudenmayer K, Haukoos JS, Sahni R, Kuppermann N. Patient choice in the selection of hospitals by 9-1-1 emergency medical services providers in trauma systems. Acad Emerg Med. 2013 Sep; 20(9):911-9. PMID: 24050797; PMCID: PMC3785298.
    124. Nigrovic LE, Schonfeld D, Dayan PS, Fitz BM, Mitchell SR, Kuppermann N. Nurse and physician agreement in the assessment of minor blunt head trauma. Pediatrics. 2013 Sep; 132(3):e689-94. PMID: 23979081.
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    125. Dalziel SR, Thompson JM, Macias CG, Fernandes RM, Johnson DW, Waisman Y, Cheng N, Acworth J, Chamberlain JM, Osmond MH, Plint A, Valerio P, Black KJ, Fitzpatrick E, Newton AS, Kuppermann N, Klassen TP. Predictors of severe H1N1 infection in children presenting within Pediatric Emergency Research Networks (PERN): retrospective case-control study. BMJ. 2013 Aug 12; 347:f4836. PMID: 23940290; PMCID: PMC3741086.
    126. Sheehan B, Nigrovic LE, Dayan PS, Kuppermann N, Ballard DW, Alessandrini E, Bajaj L, Goldberg H, Hoffman J, Offerman SR, Mark DG, Swietlik M, Tham E, Tzimenatos L, Vinson DR, Jones GS, Bakken S. Informing the design of clinical decision support services for evaluation of children with minor blunt head trauma in the emergency department: a sociotechnical analysis. J Biomed Inform. 2013 Oct; 46(5):905-13. PMID: 23892207.
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    127. Rogers AJ, Maher CO, Schunk JE, Quayle K, Jacobs E, Lichenstein R, Powell E, Miskin M, Dayan P, Holmes JF, Kuppermann N. Incidental findings in children with blunt head trauma evaluated with cranial CT scans. Pediatrics. 2013 Aug; 132(2):e356-63. PMID: 23878053.
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    128. Glaser NS, Tancredi DJ, Marcin JP, Caltagirone R, Lee Y, Murphy C, Kuppermann N. Cerebral hyperemia measured with near infrared spectroscopy during treatment of diabetic ketoacidosis in children. J Pediatr. 2013 Oct; 163(4):1111-6. PMID: 23871731.
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    129. Newgard CD, Hsia RY, Mann NC, Schmidt T, Sahni R, Bulger EM, Wang NE, Holmes JF, Fleischman R, Zive D, Staudenmayer K, Haukoos JS, Kuppermann N. The trade-offs in field trauma triage: a multiregion assessment of accuracy metrics and volume shifts associated with different triage strategies. J Trauma Acute Care Surg. 2013 May; 74(5):1298-306; discussion 1306. PMID: 23609282; PMCID: PMC3726266.
    130. Yen K, Kuppermann N, Lillis K, Monroe D, Borgialli D, Kerrey BT, Sokolove PE, Ellison AM, Cook LJ, Holmes JF. Interobserver agreement in the clinical assessment of children with blunt abdominal trauma. Acad Emerg Med. 2013 May; 20(5):426-32. PMID: 23672355.
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    131. Kerrey BT, Rogers AJ, Lee LK, Adelgais K, Tunik M, Blumberg SM, Quayle KS, Sokolove PE, Wisner DH, Miskin ML, Kuppermann N, Holmes JF. A multicenter study of the risk of intra-abdominal injury in children after normal abdominal computed tomography scan results in the emergency department. Ann Emerg Med. 2013 Oct; 62(4):319-26. PMID: 23622949.
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    132. Kim EG, Brown KM, Leonard JC, Jaffe DM, Olsen CS, Kuppermann N. Variability of prehospital spinal immobilization in children at risk for cervical spine injury. Pediatr Emerg Care. 2013 Apr; 29(4):413-8. PMID: 23528499.
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    133. Ballard DW, Rauchwerger AS, Reed ME, Vinson DR, Mark DG, Offerman SR, Chettipally UK, Graetz I, Dayan P, Kuppermann N. Emergency physicians' knowledge and attitudes of clinical decision support in the electronic health record: a survey-based study. Acad Emerg Med. 2013 Apr; 20(4):352-60. PMID: 23701342.
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    134. Glaser NS, Ghetti S, Casper TC, Dean JM, Kuppermann N. Pediatric diabetic ketoacidosis, fluid therapy, and cerebral injury: the design of a factorial randomized controlled trial. Pediatr Diabetes. 2013 Sep; 14(6):435-46. PMID: 23490311; PMCID: PMC3687019.
    135. Holmes JF, Lillis K, Monroe D, Borgialli D, Kerrey BT, Mahajan P, Adelgais K, Ellison AM, Yen K, Atabaki S, Menaker J, Bonsu B, Quayle KS, Garcia M, Rogers A, Blumberg S, Lee L, Tunik M, Kooistra J, Kwok M, Cook LJ, Dean JM, Sokolove PE, Wisner DH, Ehrlich P, Cooper A, Dayan PS, Wootton-Gorges S, Kuppermann N. Identifying children at very low risk of clinically important blunt abdominal injuries. Ann Emerg Med. 2013 Aug; 62(2):107-116.e2. PMID: 23375510.
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    136. Sokolove PE, Kuppermann N, Vance CW, Lee MO, Morris BA, Holmes JF. Variation in specialists' reported hospitalization practices of children sustaining blunt abdominal trauma. West J Emerg Med. 2013 Feb; 14(1):37-46. PMID: 23447755; PMCID: PMC3582521.
    137. Vance CW, Lee MO, Holmes JF, Sokolove PE, Palchak MJ, Morris BA, Kuppermann N. Variation in specialists' reported hospitalization practices of children sustaining blunt head trauma. West J Emerg Med. 2013 Feb; 14(1):29-36. PMID: 23447754; PMCID: PMC3582520.
    138. Glaser NS, Wootton-Gorges SL, Buonocore MH, Tancredi DJ, Marcin JP, Caltagirone R, Lee Y, Murphy C, Kuppermann N. Subclinical cerebral edema in children with diabetic ketoacidosis randomized to 2 different rehydration protocols. Pediatrics. 2013 Jan; 131(1):e73-80. PMID: 23230065.
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    139. Newgard CD, Beeson MS, Kessler CS, Kuppermann N, Linden JA, Gallahue F, Wolf S, Hatten B, Akhtar S, Dooley-Hash SL, Yarris L. Establishing an emergency medicine education research network. Acad Emerg Med. 2012 Dec; 19(12):1468-75. PMID: 23279253.
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    140. Nigrovic LE, Lillis K, Atabaki SM, Dayan PS, Hoyle J, Tunik MG, Jacobs ES, Monroe D, Wootton-Gorges SW, Miskin M, Holmes JF, Kuppermann N. The prevalence of traumatic brain injuries after minor blunt head trauma in children with ventricular shunts. Ann Emerg Med. 2013 Apr; 61(4):389-93. PMID: 23122954.
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    141. Lichenstein R, Glass TF, Quayle KS, Wootton-Gorges SL, Wisner DH, Miskin M, Muizelaar JP, Badawy M, Atabaki S, Holmes JF, Kuppermann N. Presentations and outcomes of children with intraventricular hemorrhages after blunt head trauma. Arch Pediatr Adolesc Med. 2012 Aug; 166(8):725-31. PMID: 22473883.
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    142. Natale JE, Joseph JG, Rogers AJ, Mahajan P, Cooper A, Wisner DH, Miskin ML, Hoyle JD, Atabaki SM, Dayan PS, Holmes JF, Kuppermann N. Cranial computed tomography use among children with minor blunt head trauma: association with race/ethnicity. Arch Pediatr Adolesc Med. 2012 Aug; 166(8):732-7. PMID: 22869404.
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    143. Nigrovic LE, Malley R, Kuppermann N. Meta-analysis of bacterial meningitis score validation studies. Arch Dis Child. 2012 Sep; 97(9):799-805. PMID: 22764093.
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    144. Nakamura Y, Daya M, Bulger EM, Schreiber M, Mackersie R, Hsia RY, Mann NC, Holmes JF, Staudenmayer K, Sturges Z, Liao M, Haukoos J, Kuppermann N, Barton ED, Newgard CD. Evaluating age in the field triage of injured persons. Ann Emerg Med. 2012 Sep; 60(3):335-45. PMID: 22633339; PMCID: PMC3428427.
    145. Newgard CD, Kampp M, Nelson M, Holmes JF, Zive D, Rea T, Bulger EM, Liao M, Sherck J, Hsia RY, Wang NE, Fleischman RJ, Barton ED, Daya M, Heineman J, Kuppermann N. Deciphering the use and predictive value of "emergency medical services provider judgment" in out-of-hospital trauma triage: a multisite, mixed methods assessment. J Trauma Acute Care Surg. 2012 May; 72(5):1239-48. PMID: 22673250; PMCID: PMC3376024.
    146. Newgard C, Malveau S, Staudenmayer K, Wang NE, Hsia RY, Mann NC, Holmes JF, Kuppermann N, Haukoos JS, Bulger EM, Dai M, Cook LJ. Evaluating the use of existing data sources, probabilistic linkage, and multiple imputation to build population-based injury databases across phases of trauma care. Acad Emerg Med. 2012 Apr; 19(4):469-80. PMID: 22506952.
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    147. Corneli HM, Zorc JJ, Holubkov R, Bregstein JS, Brown KM, Mahajan P, Kuppermann N. Bronchiolitis: clinical characteristics associated with hospitalization and length of stay. Pediatr Emerg Care. 2012 Feb; 28(2):99-103. PMID: 22270499.
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    148. Nigrovic LE, Lee LK, Hoyle J, Stanley RM, Gorelick MH, Miskin M, Atabaki SM, Dayan PS, Holmes JF, Kuppermann N. Prevalence of clinically important traumatic brain injuries in children with minor blunt head trauma and isolated severe injury mechanisms. Arch Pediatr Adolesc Med. 2012 Apr; 166(4):356-61. PMID: 22147762.
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    149. Maguire JL, Kulik DM, Laupacis A, Kuppermann N, Uleryk EM, Parkin PC. Clinical prediction rules for children: a systematic review. Pediatrics. 2011 Sep; 128(3):e666-77. PMID: 21859912.
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    150. Schnadower D, Kuppermann N, Macias CG, Freedman SB, Baskin MN, Ishimine P, Scribner C, Okada P, Beach H, Bulloch B, Agrawal D, Saunders M, Sutherland DM, Blackstone MM, Sarnaik A, McManemy J, Brent A, Bennett J, Plymale JM, Solari P, Mann DJ, Dayan PS. Sterile cerebrospinal fluid pleocytosis in young febrile infants with urinary tract infections. Arch Pediatr Adolesc Med. 2011 Jul; 165(7):635-41. PMID: 21727275.
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    151. Holmes JF, Borgialli DA, Nadel FM, Quayle KS, Schambam N, Cooper A, Schunk JE, Miskin ML, Atabaki SM, Hoyle JD, Dayan PS, Kuppermann N. Do children with blunt head trauma and normal cranial computed tomography scan results require hospitalization for neurologic observation? Ann Emerg Med. 2011 Oct; 58(4):315-22. PMID: 21683474.
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    152. Nigrovic LE, Schunk JE, Foerster A, Cooper A, Miskin M, Atabaki SM, Hoyle J, Dayan PS, Holmes JF, Kuppermann N. The effect of observation on cranial computed tomography utilization for children after blunt head trauma. Pediatrics. 2011 Jun; 127(6):1067-73. PMID: 21555498.
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    153. Dayan PS, Lillis K, Bennett J, Conners G, Bailey P, Callahan J, Akman C, Feldstein N, Hauser WA, Kuppermann N. Interobserver agreement in the assessment of clinical findings in children with first unprovoked seizures. Pediatrics. 2011 May; 127(5):e1266-71. PMID: 21482615.
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    154. Abo A, Kelley K, Kuppermann N, Cusick S. Ultrasound equipment for the pediatric emergency department: a review. Pediatr Emerg Care. 2011 Mar; 27(3):220-6; quiz 227-9. PMID: 21378527.
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    155. Marcin JP, Kuppermann N, Tancredi DJ, Glaser NS. Insulin administration for treatment of pediatric diabetic ketoacidosis: are lower rates of infusion beneficial? Pediatr Crit Care Med. 2011 Mar; 12(2):217-9. PMID: 21646943.
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    156. Wasserman R, Serwint JR, Kuppermann N, Srivastava R, Dreyer B. The APA and the rise of pediatric generalist network research. Acad Pediatr. 2011 May-Jun; 11(3):195-204. PMID: 21282083; PMCID: PMC3090720.
    157. Lee LK, Dayan PS, Gerardi MJ, Borgialli DA, Badawy MK, Callahan JM, Lillis KA, Stanley RM, Gorelick MH, Dong L, Zuspan SJ, Holmes JF, Kuppermann N. Intracranial hemorrhage after blunt head trauma in children with bleeding disorders. J Pediatr. 2011 Jun; 158(6):1003-1008.e1-2. PMID: 21232760.
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    158. Schnadower D, Kuppermann N, Macias CG, Freedman SB, Baskin MN, Ishimine P, Scribner C, Okada P, Beach H, Bulloch B, Agrawal D, Saunders M, Sutherland DM, Blackstone MM, Sarnaik A, McManemy J, Brent A, Bennett J, Plymale JM, Solari P, Mann DJ, Dayan PS. Febrile infants with urinary tract infections at very low risk for adverse events and bacteremia. Pediatrics. 2010 Dec; 126(6):1074-83. PMID: 21098155.
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    159. Nigrovic LE, Malley R, Agrawal D, Kuppermann N. Low risk of bacterial meningitis in children with a positive enteroviral polymerase chain reaction test result. Clin Infect Dis. 2010 Nov 15; 51(10):1221-2. PMID: 20964523.
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    160. Kaji AH, Lewis RJ, Beavers-May T, Berg R, Bulger E, Cairns C, Callaway C, Camargo CA, Carcillo J, DeBiasi R, Diaz T, Ducharme F, Glickman S, Heilpern K, Hickey R, Hoek TV, Hollander J, Janson S, Jurkovich G, Kellermann A, Kingsmore S, Kline J, Kuppermann N, Lowe R, McLario D, Nathanson L, Nichol G, Peitzman A, Richardson L, Sanders A, Shah M, Shapiro N, Silverman R, Than M, Wilber S, Yealy DM. Summary of NIH Medical-Surgical Emergency Research Roundtable held on April 30 to May 1, 2009. Ann Emerg Med. 2010 Nov; 56(5):522-37. PMID: 21036293.
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    161. D'Onofrio G, Jauch E, Jagoda A, Allen MH, Anglin D, Barsan WG, Berger RP, Bobrow BJ, Boudreaux ED, Bushnell C, Chan YF, Currier G, Eggly S, Ichord R, Larkin GL, Laskowitz D, Neumar RW, Newman-Toker DE, Quinn J, Shear K, Todd KH, Zatzick D. NIH Roundtable on Opportunities to Advance Research on Neurologic and Psychiatric Emergencies. Ann Emerg Med. 2010 Nov; 56(5):551-64. PMID: 21036295.
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    162. Leonard JC, Kuppermann N, Olsen C, Babcock-Cimpello L, Brown K, Mahajan P, Adelgais KM, Anders J, Borgialli D, Donoghue A, Hoyle JD, Kim E, Leonard JR, Lillis KA, Nigrovic LE, Powell EC, Rebella G, Reeves SD, Rogers AJ, Stankovic C, Teshome G, Jaffe DM. Factors associated with cervical spine injury in children after blunt trauma. Ann Emerg Med. 2011 Aug; 58(2):145-55. PMID: 21035905.
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    163. Klassen TP, Acworth J, Bialy L, Black K, Chamberlain JM, Cheng N, Dalziel S, Fernandes RM, Fitzpatrick E, Johnson DW, Kuppermann N, Macias CG, Newton M, Osmond MH, Plint A, Valerio P, Waisman Y. Pediatric emergency research networks: a global initiative in pediatric emergency medicine. Pediatr Emerg Care. 2010 Aug; 26(8):541-3. PMID: 20657343.
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    164. Klassen TP, Acworth J, Bialy L, Black K, Chamberlain JM, Cheng N, Dalziel S, Fernandes RM, Fitzpatrick E, Johnson DW, Kuppermann N, Macias CG, Newton M, Osmond MH, Plint A, Valerio P, Waisman Y. Pediatric Emergency Research Networks: a global initiative in pediatric emergency medicine. Eur J Emerg Med. 2010 Aug; 17(4):224-7. PMID: 20523220.
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    165. Wootton-Gorges SL, Buonocore MH, Caltagirone RA, Kuppermann N, Glaser NS. Progressive decrease in N-acetylaspartate/Creatine ratio in a teenager with type 1 diabetes and repeated episodes of ketoacidosis without clinically apparent cerebral edema: Evidence for permanent brain injury. AJNR Am J Neuroradiol. 2010 Apr; 31(4):780-1. PMID: 19926705.
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    166. Papa L, Kuppermann N, Lamond K, Barsan WG, Camargo CA, Ornato JP, Stiell IG, Talan DA. Structure and function of emergency care research networks: strengths, weaknesses, and challenges. Acad Emerg Med. 2009 Oct; 16(10):995-1004. PMID: 19799579.
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    167. Kuppermann N, Holmes JF, Dayan PS, Hoyle JD, Atabaki SM, Holubkov R, Nadel FM, Monroe D, Stanley RM, Borgialli DA, Badawy MK, Schunk JE, Quayle KS, Mahajan P, Lichenstein R, Lillis KA, Tunik MG, Jacobs ES, Callahan JM, Gorelick MH, Glass TF, Lee LK, Bachman MC, Cooper A, Powell EC, Gerardi MJ, Melville KA, Muizelaar JP, Wisner DH, Zuspan SJ, Dean JM, Wootton-Gorges SL. Identification of children at very low risk of clinically-important brain injuries after head trauma: a prospective cohort study. Lancet. 2009 Oct 03; 374(9696):1160-70. PMID: 19758692.
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    168. Oh G, Anderson S, Tancredi D, Kuppermann N, Glaser N. Hyponatremia in pediatric diabetic ketoacidosis: reevaluating the correction factor for hyperglycemia. Arch Pediatr Adolesc Med. 2009 Aug; 163(8):771-2. PMID: 19652113.
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    169. Chamberlain JM, Lillis K, Vance C, Brown KM, Fawumi O, Nichols S, Davis CO, Singh T, Baren JM. Perceived challenges to obtaining informed consent for a time-sensitive emergency department study of pediatric status epilepticus: results of two focus groups. Acad Emerg Med. 2009 Aug; 16(8):763-70. PMID: 19673713; PMCID: PMC4449133.
    170. Krief WI, Levine DA, Platt SL, Macias CG, Dayan PS, Zorc JJ, Feffermann N, Kuppermann N. Influenza virus infection and the risk of serious bacterial infections in young febrile infants. Pediatrics. 2009 Jul; 124(1):30-9. PMID: 19564280.
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    171. Holmes JF, Wisner DH, McGahan JP, Mower WR, Kuppermann N. Clinical prediction rules for identifying adults at very low risk for intra-abdominal injuries after blunt trauma. Ann Emerg Med. 2009 Oct; 54(4):575-84. PMID: 19457583.
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    172. Kanegaye JT, Nigrovic LE, Malley R, Cannavino CR, Schwab SH, Bennett JE, Mohseni MM, Wang VJ, Katsogridakis YL, Herman MI, Kuppermann N. Diagnostic value of immature neutrophils (bands) in the cerebrospinal fluid of children with cerebrospinal fluid pleocytosis. Pediatrics. 2009 Jun; 123(6):e967-71. PMID: 19451189.
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    173. Holmes JF, Mao A, Awasthi S, McGahan JP, Wisner DH, Kuppermann N. Validation of a prediction rule for the identification of children with intra-abdominal injuries after blunt torso trauma. Ann Emerg Med. 2009 Oct; 54(4):528-33. PMID: 19250706.
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    174. Palchak MJ, Holmes JF, Kuppermann N. Clinician judgment versus a decision rule for identifying children at risk of traumatic brain injury on computed tomography after blunt head trauma. Pediatr Emerg Care. 2009 Feb; 25(2):61-5. PMID: 19194349.
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    175. Nigrovic LE, Malley R, Kuppermann N. Cerebrospinal fluid pleocytosis in children in the era of bacterial conjugate vaccines: distinguishing the child with bacterial and aseptic meningitis. Pediatr Emerg Care. 2009 Feb; 25(2):112-7; quiz 118-20. PMID: 19225382.
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    176. Holmes JF, Holubkov R, Kuppermann N. Guardian availability in children evaluated in the emergency department for blunt head trauma. Acad Emerg Med. 2009 Jan; 16(1):15-20. PMID: 19021587.
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    177. Bair AE, Rose JS, Vance CW, Andrada-Brown E, Kuppermann N. Ultrasound-assisted peripheral venous access in young children: a randomized controlled trial and pilot feasibility study. West J Emerg Med. 2008 Nov; 9(4):219-24. PMID: 19561750; PMCID: PMC2672282.
    178. Nigrovic LE, Malley R, Macias CG, Kanegaye JT, Moro-Sutherland DM, Schremmer RD, Schwab SH, Agrawal D, Mansour KM, Bennett JE, Katsogridakis YL, Mohseni MM, Bulloch B, Steele DW, Kaplan RL, Herman MI, Bandyopadhyay S, Dayan P, Truong UT, Wang VJ, Bonsu BK, Chapman JL, Kuppermann N. Effect of antibiotic pretreatment on cerebrospinal fluid profiles of children with bacterial meningitis. Pediatrics. 2008 Oct; 122(4):726-30. PMID: 18829794.
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    179. Kuppermann N. Pediatric head trauma: the evidence regarding indications for emergent neuroimaging. Pediatr Radiol. 2008 Nov; 38 Suppl 4:S670-4. PMID: 18810402.
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    180. Awasthi S, Mao A, Wooton-Gorges SL, Wisner DH, Kuppermann N, Holmes JF. Is hospital admission and observation required after a normal abdominal computed tomography scan in children with blunt abdominal trauma? Acad Emerg Med. 2008 Oct; 15(10):895-9. PMID: 18778379.
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    181. Gorelick MH, Atabaki SM, Hoyle J, Dayan PS, Holmes JF, Holubkov R, Monroe D, Callahan JM, Kuppermann N. Interobserver agreement in assessment of clinical variables in children with blunt head trauma. Acad Emerg Med. 2008 Sep; 15(9):812-8. PMID: 19244631.
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    182. Shah SS, Zorc JJ, Levine DA, Platt SL, Kuppermann N. Sterile cerebrospinal fluid pleocytosis in young infants with urinary tract infections. J Pediatr. 2008 Aug; 153(2):290-2. PMID: 18639733.
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    183. Dharmar M, Marcin JP, Romano PS, Andrada ER, Overly F, Valente JH, Harvey DJ, Cole SL, Kuppermann N. Quality of care of children in the emergency department: association with hospital setting and physician training. J Pediatr. 2008 Dec; 153(6):783-9. PMID: 18617191.
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    184. Quiros JA, Marcin JP, Kuppermann N, Nasrollahzadeh F, Rewers A, DiCarlo J, Neely EK, Glaser N. Elevated serum amylase and lipase in pediatric diabetic ketoacidosis. Pediatr Crit Care Med. 2008 Jul; 9(4):418-22. PMID: 18496406.
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    185. Glaser NS, Marcin JP, Wootton-Gorges SL, Buonocore MH, Rewers A, Strain J, DiCarlo J, Neely EK, Barnes P, Kuppermann N. Correlation of clinical and biochemical findings with diabetic ketoacidosis-related cerebral edema in children using magnetic resonance diffusion-weighted imaging. J Pediatr. 2008 Oct; 153(4):541-6. PMID: 18589447.
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    186. Kuppermann N, Park J, Glatter K, Marcin JP, Glaser NS. Prolonged QT interval corrected for heart rate during diabetic ketoacidosis in children. Arch Pediatr Adolesc Med. 2008 Jun; 162(6):544-9. PMID: 18524745.
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    187. Nigrovic LE, Kuppermann N, Malley R. Children with bacterial meningitis presenting to the emergency department during the pneumococcal conjugate vaccine era. Acad Emerg Med. 2008 Jun; 15(6):522-8. PMID: 18616437.
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    188. Miller SZ, Rincón H, Kuppermann N. Revisiting the emergency medicine services for children research agenda: priorities for multicenter research in pediatric emergency care. Acad Emerg Med. 2008 Apr; 15(4):377-83. PMID: 18370994.
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    189. Glaser N, Kuppermann N. DKA-related cerebral edema and intravenous fluid therapy: potential pitfalls of uncontrolled retrospective studies. J Pediatr. 2008 Jan; 152(1):145; author reply 147-9. PMID: 18154922.
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    190. Dayan PS, Osmond M, Kuppermann N, Lang E, Klassen T, Johnson D, Strauss S, Hess E, Schneider S, Afilalo M, Pusic M. Development of the capacity necessary to perform and promote knowledge translation research in emergency medicine. Acad Emerg Med. 2007 Nov; 14(11):978-83. PMID: 17967959.
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    191. Glaser N, Kuppermann N, Marcin J, Schalick WO. A comment on "The risky business of assessing research risk". Am J Bioeth. 2007 Nov; 7(11):W5-6. PMID: 18027288.
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    192. Dharmar M, Marcin JP, Kuppermann N, Andrada ER, Cole S, Harvey DJ, Romano PS. A new implicit review instrument for measuring quality of care delivered to pediatric patients in the emergency department. BMC Emerg Med. 2007 Aug 23; 7:13. PMID: 17714593; PMCID: PMC2000874.
    193. Corneli HM, Zorc JJ, Mahajan P, Majahan P, Shaw KN, Holubkov R, Reeves SD, Ruddy RM, Malik B, Nelson KA, Bregstein JS, Brown KM, Denenberg MN, Lillis KA, Cimpello LB, Tsung JW, Borgialli DA, Baskin MN, Teshome G, Goldstein MA, Monroe D, Dean JM, Kuppermann N. A multicenter, randomized, controlled trial of dexamethasone for bronchiolitis. N Engl J Med. 2007 Jul 26; 357(4):331-9. PMID: 17652648.
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    194. Gorelick MH, Knight S, Alessandrini EA, Stanley RM, Chamberlain JM, Kuppermann N, Alpern ER. Lack of agreement in pediatric emergency department discharge diagnoses from clinical and administrative data sources. Acad Emerg Med. 2007 Jul; 14(7):646-52. PMID: 17554009.
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    195. Wootton-Gorges SL, Buonocore MH, Kuppermann N, Marcin JP, Barnes PD, Neely EK, DiCarlo J, McCarthy T, Glaser NS. Cerebral proton magnetic resonance spectroscopy in children with diabetic ketoacidosis. AJNR Am J Neuroradiol. 2007 May; 28(5):895-9. PMID: 17494665.
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    196. Nigrovic LE, Kuppermann N, Neuman MI. Risk factors for traumatic or unsuccessful lumbar punctures in children. Ann Emerg Med. 2007 Jun; 49(6):762-71. PMID: 17321005.
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    197. Edwards P, Fernandes J, Roberts I, Kuppermann N. Young men were at risk of becoming lost to follow-up in a cohort of head-injured adults. J Clin Epidemiol. 2007 Apr; 60(4):417-24. PMID: 17346617.
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    198. Nigrovic LE, Kuppermann N, Macias CG, Cannavino CR, Moro-Sutherland DM, Schremmer RD, Schwab SH, Agrawal D, Mansour KM, Bennett JE, Katsogridakis YL, Mohseni MM, Bulloch B, Steele DW, Kaplan RL, Herman MI, Bandyopadhyay S, Dayan P, Truong UT, Wang VJ, Bonsu BK, Chapman JL, Kanegaye JT, Malley R. Clinical prediction rule for identifying children with cerebrospinal fluid pleocytosis at very low risk of bacterial meningitis. JAMA. 2007 Jan 03; 297(1):52-60. PMID: 17200475.
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    199. Blackwell CD, Gorelick M, Holmes JF, Bandyopadhyay S, Kuppermann N. Pediatric head trauma: changes in use of computed tomography in emergency departments in the United States over time. Ann Emerg Med. 2007 Mar; 49(3):320-4. PMID: 17145113.
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    200. Alpern ER, Stanley RM, Gorelick MH, Donaldson A, Knight S, Teach SJ, Singh T, Mahajan P, Goepp JG, Kuppermann N, Dean JM, Chamberlain JM. Epidemiology of a pediatric emergency medicine research network: the PECARN Core Data Project. Pediatr Emerg Care. 2006 Oct; 22(10):689-99. PMID: 17047467.
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    201. Glaser NS, Wootton-Gorges SL, Buonocore MH, Marcin JP, Rewers A, Strain J, DiCarlo J, Neely EK, Barnes P, Kuppermann N. Frequency of sub-clinical cerebral edema in children with diabetic ketoacidosis. Pediatr Diabetes. 2006 Apr; 7(2):75-80. PMID: 16629712.
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    202. Gorelick MH, Alpern ER, Singh T, Snowdon D, Holubkov R, Dean JM, Kuppermann N. Availability of pediatric emergency visit data from existing data sources. Acad Emerg Med. 2005 Dec; 12(12):1195-200. PMID: 16282514.
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    203. Zorc JJ, Levine DA, Platt SL, Dayan PS, Macias CG, Krief W, Schor J, Bank D, Shaw KN, Kuppermann N. Clinical and demographic factors associated with urinary tract infection in young febrile infants. Pediatrics. 2005 Sep; 116(3):644-8. PMID: 16140703.
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    204. Holmes JF, Palchak MJ, MacFarlane T, Kuppermann N. Performance of the pediatric glasgow coma scale in children with blunt head trauma. Acad Emerg Med. 2005 Sep; 12(9):814-9. PMID: 16141014.
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    205. Sokolove PE, Kuppermann N, Holmes JF. Association between the "seat belt sign" and intra-abdominal injury in children with blunt torso trauma. Acad Emerg Med. 2005 Sep; 12(9):808-13. PMID: 16141013.
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    206. Rose JS, Richards JR, Battistella F, Bair AE, McGahan JP, Kuppermann N. The fast is positive, now what? Derivation of a clinical decision rule to determine the need for therapeutic laparotomy in adults with blunt torso trauma and a positive trauma ultrasound. J Emerg Med. 2005 Jul; 29(1):15-21. PMID: 15961002.
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    207. Marcin JP, Glaser N, Kuppermann N. Ventilation in pediatric diabetic ketoacidosis--not too much, but not too little. Pediatr Crit Care Med. 2005 Jul; 6(4):489-90. PMID: 15982442.
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    208. Wootton-Gorges SL, Buonocore MH, Kuppermann N, Marcin J, Dicarlo J, Neely EK, Barnes PD, Glaser N. Detection of cerebral {beta}-hydroxy butyrate, acetoacetate, and lactate on proton MR spectroscopy in children with diabetic ketoacidosis. AJNR Am J Neuroradiol. 2005 May; 26(5):1286-91. PMID: 15891198.
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    209. Krug S, Kuppermann N. Twenty years of emergency medical services for children: a cause for celebration and a call for action. Pediatrics. 2005 Apr; 115(4):1089-91. PMID: 15805395.
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    210. Krug S, Kuppermann N. Twenty years of emergency medical services for children: a cause for celebration and a call for action. Pediatr Emerg Care. 2005 Apr; 21(4):223-6. PMID: 15824680.
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    211. Krug S, Kuppermann N. Twenty years of emergency medical services for children--a cause for celebration and a call for action. Acad Emerg Med. 2005 Apr; 12(4):345-7. PMID: 15805326.
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    212. Rosival V. Diabetic ketoacidosis. Pediatr Emerg Care. 2005 Jan; 21(1):76; author reply 76-7. PMID: 15643333.
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    213. Kuppermann N, Palchak MJ, Holmes JF. Loss of consciousness and/or amnesia after blunt head trauma in children. Pediatr Crit Care Med. 2005 Jan; 6(1):93-4. PMID: 15643308.
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    214. Nigrovic LE, Kuppermann N, McAdam AJ, Malley R. Cerebrospinal latex agglutination fails to contribute to the microbiologic diagnosis of pretreated children with meningitis. Pediatr Infect Dis J. 2004 Aug; 23(8):786-8. PMID: 15295235.
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    215. Glaser NS, Wootton-Gorges SL, Marcin JP, Buonocore MH, Dicarlo J, Neely EK, Barnes P, Bottomly J, Kuppermann N. Mechanism of cerebral edema in children with diabetic ketoacidosis. J Pediatr. 2004 Aug; 145(2):164-71. PMID: 15289761.
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    216. Kuppermann N. Intracranial injury in minor head trauma. Arch Dis Child. 2004 Jul; 89(7):593-4. PMID: 15210483; PMCID: PMC1719982.
    217. Dayan PS, Vitale M, Langsam DJ, Ruzal-Shapiro C, Novick MK, Kuppermann N, Miller SZ. Derivation of clinical prediction rules to identify children with fractures after twisting injuries of the ankle. Acad Emerg Med. 2004 Jul; 11(7):736-43. PMID: 15231460.
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    218. Babcock-Cimpello L, Blyth B, Bazarian JJ. Decision rules for computed tomographic scans in children after head trauma. Ann Emerg Med. 2004 Jul; 44(1):90-1; author reply 91-2. PMID: 15259171.
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    219. Glaser N, Kuppermann N. The evaluation and management of children with diabetic ketoacidosis in the emergency department. Pediatr Emerg Care. 2004 Jul; 20(7):477-81; quiz 482-4. PMID: 15232253.
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    220. Holmes JF, Palchak MJ, Conklin MJ, Kuppermann N. Do children require hospitalization after immediate posttraumatic seizures? Ann Emerg Med. 2004 Jun; 43(6):706-10. PMID: 15159700.
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    221. Levine DA, Platt SL, Dayan PS, Macias CG, Zorc JJ, Krief W, Schor J, Bank D, Fefferman N, Shaw KN, Kuppermann N. Risk of serious bacterial infection in young febrile infants with respiratory syncytial virus infections. Pediatrics. 2004 Jun; 113(6):1728-34. PMID: 15173498.
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    222. Palchak MJ, Holmes JF, Vance CW, Gelber RE, Schauer BA, Harrison MJ, Willis-Shore J, Wootton-Gorges SL, Derlet RW, Kuppermann N. Does an isolated history of loss of consciousness or amnesia predict brain injuries in children after blunt head trauma? Pediatrics. 2004 Jun; 113(6):e507-13. PMID: 15173529.
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    223. Palchak MJ, Holmes JF, Vance CW, Gelber RE, Schauer BA, Harrison MJ, Willis-Shore J, Wootton-Gorges SL, Derlet RW, Kuppermann N. A decision rule for identifying children at low risk for brain injuries after blunt head trauma. Ann Emerg Med. 2003 Oct; 42(4):492-506. PMID: 14520320.
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    224. Haruda FD. Meningitis--viral versus bacterial. Pediatrics. 2003 Aug; 112(2):447-8; author reply 447-8. PMID: 12897308.
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    225. Kuppermann N. Diagnostic testing of the febrile neonate: it is time to collaborate. Arch Pediatr Adolesc Med. 2003 Jun; 157(6):508-9. PMID: 12796228.
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    226. Bair AE, Laurin EG, Karchin A, Richards JR, Kuppermann N. Cricoid ring integrity: implications for cricothyrotomy. Ann Emerg Med. 2003 Mar; 41(3):331-7. PMID: 12605199.
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    227. Kuppermann N, Malley R, Huskins WC. A new prognostic scoring system for meningococcal septic shock in children: comparison with three other scoring systems. Intensive Care Med. 2003 Feb; 29(2):333; author reply 334. PMID: 12594597.
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    228. Marcin JP, Glaser N, Barnett P, McCaslin I, Nelson D, Trainor J, Louie J, Kaufman F, Quayle K, Roback M, Malley R, Kuppermann N. Factors associated with adverse outcomes in children with diabetic ketoacidosis-related cerebral edema. J Pediatr. 2002 Dec; 141(6):793-7. PMID: 12461495.
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    229. Nigrovic LE, Kuppermann N, Malley R. Development and validation of a multivariable predictive model to distinguish bacterial from aseptic meningitis in children in the post-Haemophilus influenzae era. Pediatrics. 2002 Oct; 110(4):712-9. PMID: 12359784.
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    230. Kuppermann N. Respiratory syncytial virus infection and the risk of serious bacterial infections. Arch Pediatr Adolesc Med. 2002 Oct; 156(10):1055-6; author reply 1056-7. PMID: 12361456.
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    231. Kuppermann N. The evaluation of young febrile children for occult bacteremia: time to reevaluate our approach? Arch Pediatr Adolesc Med. 2002 Sep; 156(9):855-7. PMID: 12197789.
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    232. Nguyen T, Malley R, Inkelis S, Kuppermann N. Comparison of prediction models for adverse outcome in pediatric meningococcal disease using artificial neural network and logistic regression analyses. J Clin Epidemiol. 2002 Jul; 55(7):687-95. PMID: 12160917.
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    233. Inkelis SH, O'Leary D, Wang VJ, Malley R, Nicholson MK, Kuppermann N. Extremity pain and refusal to walk in children with invasive meningococcal disease. Pediatrics. 2002 Jul; 110(1 Pt 1):e3. PMID: 12093984.
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    234. Sayre MR, White LJ, Brown LH, McHenry SD. National EMS Research Agenda. Prehosp Emerg Care. 2002 Jul-Sep; 6(3 Suppl):S1-43. PMID: 12108581.
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    235. Holmes JF, Sokolove PE, Brant WE, Kuppermann N. A clinical decision rule for identifying children with thoracic injuries after blunt torso trauma. Ann Emerg Med. 2002 May; 39(5):492-9. PMID: 11973556.
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    236. West DC, Andrada E, Azari R, Rangaswami AA, Kuppermann N. Predictors of bacteremia in febrile children with sickle cell disease. J Pediatr Hematol Oncol. 2002 May; 24(4):279-83. PMID: 11972096.
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    237. Holmes JF, Sokolove PE, Brant WE, Palchak MJ, Vance CW, Owings JT, Kuppermann N. Identification of children with intra-abdominal injuries after blunt trauma. Ann Emerg Med. 2002 May; 39(5):500-9. PMID: 11973557.
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    238. Yang JW, Kuppermann N, Rosas A. Child abuse presenting as pseudorenal failure with a history of a bicycle fall. Pediatr Emerg Care. 2002 Apr; 18(2):91-2. PMID: 11973499.
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    239. Holmes JF, Goodwin HC, Land C, Kuppermann N. Coagulation testing in pediatric blunt trauma patients. Pediatr Emerg Care. 2001 Oct; 17(5):324-8. PMID: 11673707.
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    240. DiTraglia J. Occult bacteremia from a pediatric emergency department. Pediatrics. 2001 Aug; 108(2):520-1. PMID: 11491117.
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    241. Holmes JF, Brant WE, Bond WF, Sokolove PE, Kuppermann N. Emergency department ultrasonography in the evaluation of hypotensive and normotensive children with blunt abdominal trauma. J Pediatr Surg. 2001 Jul; 36(7):968-73. PMID: 11431759.
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    242. Press S. Incidence of unsuspected meningococcal disease. Arch Pediatr Adolesc Med. 2001 Jun; 155(6):741. PMID: 11386976.
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    243. Gebara BM. Risk factors for cerebral edema in children with diabetic ketoacidosis. N Engl J Med. 2001 May 17; 344(20):1556. PMID: 11368049.
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    244. Wang VJ, Kuppermann N, Malley R, Barnett ED, Meissner HC, Schmidt EV, Fleisher GR. Meningococcal disease among children who live in a large metropolitan area, 1981-1996. Clin Infect Dis. 2001 Apr 01; 32(7):1004-9. PMID: 11264027.
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    245. Holmes JF, Brant WE, Bogren HG, London KL, Kuppermann N. Prevalence and importance of pneumothoraces visualized on abdominal computed tomographic scan in children with blunt trauma. J Trauma. 2001 Mar; 50(3):516-20. PMID: 11265032.
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    246. Glaser N, Barnett P, McCaslin I, Nelson D, Trainor J, Louie J, Kaufman F, Quayle K, Roback M, Malley R, Kuppermann N. Risk factors for cerebral edema in children with diabetic ketoacidosis. The Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. N Engl J Med. 2001 Jan 25; 344(4):264-9. PMID: 11172153.
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    247. Wang VJ, Malley R, Fleisher GR, Inkelis SH, Kuppermann N. Antibiotic treatment of children with unsuspected meningococcal disease. Arch Pediatr Adolesc Med. 2000 Jun; 154(6):556-60. PMID: 10850501.
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    248. Holmes JF, London KL, Brant WE, Kuppermann N. Isolated intraperitoneal fluid on abdominal computed tomography in children with blunt trauma. Acad Emerg Med. 2000 Apr; 7(4):335-41. PMID: 10805620.
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    249. Kuppermann N, O'Dea T, Pinckney L, Hoecker C. Predictors of intussusception in young children. Arch Pediatr Adolesc Med. 2000 Mar; 154(3):250-5. PMID: 10710022.
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    250. Green SM, Kuppermann N, Rothrock SG, Hummel CB, Ho M. Predictors of adverse events with intramuscular ketamine sedation in children. Ann Emerg Med. 2000 Jan; 35(1):35-42. PMID: 10613938.
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    251. Kuppermann N, Willits N. In response to "Statistical Models and Occam's Razor". Acad Emerg Med. 2000 Jan; 7(1):100-3. PMID: 10894254.
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    252. Tamariz V, Kuppermann N. Federal funding opportunities for research in pediatric emergency medicine. APA-EMSC partnership for children work group on barriers to research in Pediatric Emergency Medicine: Emergency Medical Services for Children. Pediatr Emerg Care. 1999 Dec; 15(6):451-6. PMID: 10608341.
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    253. Kuppermann N. Occult bacteremia in young febrile children. Pediatr Clin North Am. 1999 Dec; 46(6):1073-109. PMID: 10629675.
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    254. Holmes JF, Sokolove PE, Land C, Kuppermann N. Identification of intra-abdominal injuries in children hospitalized following blunt torso trauma. Acad Emerg Med. 1999 Aug; 6(8):799-806. PMID: 10463551.
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    255. Kuppermann N, Walton EA. Immature neutrophils in the blood smears of young febrile children. Arch Pediatr Adolesc Med. 1999 Mar; 153(3):261-6. PMID: 10086403.
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    256. Kuppermann N, Malley R, Inkelis SH, Fleisher GR. Clinical and hematologic features do not reliably identify children with unsuspected meningococcal disease. Pediatrics. 1999 Feb; 103(2):E20. PMID: 9925866.
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    257. Nelson DG, Leake J, Bradley J, Kuppermann N. Evaluation of febrile children with petechial rashes: is there consensus among pediatricians? Pediatr Infect Dis J. 1998 Dec; 17(12):1135-40. PMID: 9877362.
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    258. Kuppermann N. Meta-analyses of treatment for occult pneumococcal bacteremia. Acad Emerg Med. 1998 Dec; 5(12):1230-1. PMID: 9864138.
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    259. Kuppermann N. Sepsis evaluations in hospitalized infants with bronchiolitis. Pediatr Infect Dis J. 1998 Oct; 17(10):937-9. PMID: 9802650.
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    260. Malley R, Inkelis SH, Coelho P, Huskins WC, Kuppermann N. Cerebrospinal fluid pleocytosis and prognosis in invasive meningococcal disease in children. Pediatr Infect Dis J. 1998 Oct; 17(10):855-9. PMID: 9802624.
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    261. St Jacques DM, Barton LL, Rhee KH. Risk of serious bacterial infections in infants with bronchiolitis. Arch Pediatr Adolesc Med. 1998 Aug; 152(8):819-20. PMID: 9701147.
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    262. Kuppermann N, Fleisher GR, Jaffe DM. Predictors of occult pneumococcal bacteremia in young febrile children. Ann Emerg Med. 1998 Jun; 31(6):679-87. PMID: 9624306.
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    263. Kuppermann N, Bank DE, Walton EA, Senac MO, McCaslin I. Risks for bacteremia and urinary tract infections in young febrile children with bronchiolitis. Arch Pediatr Adolesc Med. 1997 Dec; 151(12):1207-14. PMID: 9412595.
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    264. Glaser NS, Kuppermann N, Yee CK, Schwartz DL, Styne DM. Variation in the management of pediatric diabetic ketoacidosis by specialty training. Arch Pediatr Adolesc Med. 1997 Nov; 151(11):1125-32. PMID: 9369874.
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    265. Cremer R, Leclerc F, Martinot A, Sadik A, Fourier C. Adverse outcome in children with meningococcemia. J Pediatr. 1997 Oct; 131(4):649-51. PMID: 9386680.
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    266. Singer AJ. Corticosteroids and asthma in children. Ann Emerg Med. 1997 Sep; 30(3):355-6. PMID: 9287905.
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    267. Sharieff GQ, Francis K, Kuppermann N. Atypical presentation of Henoch-Schoenlein purpura in two children. Am J Emerg Med. 1997 Jul; 15(4):375-7. PMID: 9217530.
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    268. Quayle KS, Jaffe DM, Kuppermann N, Kaufman BA, Lee BC, Park TS, McAlister WH. Diagnostic testing for acute head injury in children: when are head computed tomography and skull radiographs indicated? Pediatrics. 1997 May; 99(5):E11. PMID: 9113968.
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    269. Barnett PL, Caputo GL, Baskin M, Kuppermann N. Intravenous versus oral corticosteroids in the management of acute asthma in children. Ann Emerg Med. 1997 Feb; 29(2):212-7. PMID: 9018184.
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    270. Malley R, Huskins WC, Kuppermann N. Multivariable predictive models for adverse outcome of invasive meningococcal disease in children. J Pediatr. 1996 Nov; 129(5):702-10. PMID: 8917237.
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    271. Weiner DL, Kuppermann N, Saladino RA, Thompson CM, Novitsky TJ, Siber GR, Fleisher GR. Comparison of early and late treatment with a recombinant endotoxin neutralizing protein in a rat model of Escherichia coli sepsis. Crit Care Med. 1996 Sep; 24(9):1514-7. PMID: 8797624.
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    272. Bird LM, Jones MC, Kuppermann N, Huskins WC. Gram-negative bacteremia in four patients with Klippel-Trenaunay-Weber syndrome. Pediatrics. 1996 May; 97(5):739-41. PMID: 8628620.
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    273. Kinnane J, Priebe C, Caty M, Kuppermann N. Perforation of the colon in an adolescent girl. Pediatr Emerg Care. 1995 Aug; 11(4):230-2. PMID: 8532569.
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    274. Nelson D, Kuppermann N, Fleisher GR, Hammer BK, Thompson CM, Garcia CT, Novitsky TJ, Parsonnet J, Onderdonk A, Siber GR. Recombinant endotoxin neutralizing protein improves survival from Escherichia coli sepsis in rats. Crit Care Med. 1995 Jan; 23(1):92-8. PMID: 8001394.
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    275. Kuppermann N, Inkelis SH, Saladino R. The role of heparin in the prevention of extremity and digit necrosis in meningococcal purpura fulminans. Pediatr Infect Dis J. 1994 Oct; 13(10):867-73. PMID: 7854884.
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    276. Kuppermann N, Nelson DS, Saladino RA, Thompson CM, Sattler F, Novitsky TJ, Fleisher GR, Siber GR. Comparison of a recombinant endotoxin-neutralizing protein with a human monoclonal antibody to endotoxin for the treatment of Escherichia coli sepsis in rats. J Infect Dis. 1994 Sep; 170(3):630-5. PMID: 8077721.
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    277. Davis JM, Kuppermann N, Fleisher G. Serious sports injuries requiring hospitalization seen in a pediatric emergency department. Am J Dis Child. 1993 Sep; 147(9):1001-4. PMID: 8362793.
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    278. Kuppermann N, Anand S. Transient infantile hypertension. West J Med. 1990 Aug; 153(2):197-9. PMID: 2219887.
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