Edward N Pugh Jr

Title(s)Professor, Physiology and Membrane Biology
SchoolSchool of Medicine
Address3301 Tupper Hall
CA 95616
vCardDownload vCard

    Collapse Research 
    Collapse Research Activities and Funding
    Translocation of soluble proteins in rod photoreceptors
    NIH/NEI R01EY016453Jun 1, 2005 - May 31, 2010
    Role: Principal Investigator
    Nanomedicine:Supra-molecular cellular compartments (RMI)
    NIH/NEI PN1EY016555Sep 30, 2004 - Mar 31, 2005
    Role: Principal Investigator
    NIH/NEI R01EY013074Sep 7, 2000 - Aug 31, 2004
    Role: Principal Investigator
    NIH/NEI R01EY008206Jul 1, 1989 - Jun 30, 1993
    Role: Principal Investigator
    Mechanisms of Visual Transduction
    NIH/NEI R01EY002660Aug 1, 1978 - Feb 28, 2022
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. In vivo imaging reveals transient microglia recruitment and functional recovery of photoreceptor signaling after injury. Proc Natl Acad Sci U S A. 2019 08 13; 116(33):16603-16612. Miller EB, Zhang P, Ching K, Pugh EN, Burns ME. PMID: 31350349; PMCID: PMC6697899.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    2. The mechanism of photon-like dark noise in rod photoreceptors. J Gen Physiol. 2019 Jul 01; 151(7):875-877. Pugh EN. PMID: 31171571; PMCID: PMC6605688.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    3. Directional optical coherence tomography reveals melanin concentration-dependent scattering properties of retinal pigment epithelium. J Biomed Opt. 2019 06; 24(6):1-10. Meleppat RK, Zhang P, Ju MJ, Manna SK, Jian Y, Pugh EN, Zawadzki RJ. PMID: 31254332; PMCID: PMC6977406.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    4. Effect of a contact lens on mouse retinal in vivo imaging: Effective focal length changes and monochromatic aberrations. Exp Eye Res. 2018 07; 172:86-93. Zhang P, Mocci J, Wahl DJ, Meleppat RK, Manna SK, Quintavalla M, Muradore R, Sarunic MV, Bonora S, Pugh EN, Zawadzki RJ. PMID: 29604280; PMCID: PMC6417837.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    5. Loss of cone function without degeneration in a novel Gnat2 knock-out mouse. Exp Eye Res. 2018 06; 171:111-118. Ronning KE, Allina GP, Miller EB, Zawadzki RJ, Pugh EN, Herrmann R, Burns ME. PMID: 29518352; PMCID: PMC5987249.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    6. The discovery of the ability of rod photoreceptors to signal single photons. J Gen Physiol. 2018 03 05; 150(3):383-388. Pugh EN. PMID: 29467164; PMCID: PMC5839725.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    7. Photoreceptor Layer Thickness Changes During Dark Adaptation Observed With Ultrahigh-Resolution Optical Coherence Tomography. Invest Ophthalmol Vis Sci. 2017 09 01; 58(11):4632-4643. Lu CD, Lee B, Schottenhamml J, Maier A, Pugh EN, Fujimoto JG. PMID: 28898357; PMCID: PMC5596796.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    8. Rapid monocyte infiltration following retinal detachment is dependent on non-canonical IL6 signaling through gp130. J Neuroinflammation. 2017 06 23; 14(1):121. Wang X, Miller EB, Goswami M, Zhang P, Ronning KE, Karlen SJ, Zawadzki RJ, Pugh EN, Burns ME. PMID: 28645275; PMCID: PMC5481880.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    9. In vivo optophysiology reveals that G-protein activation triggers osmotic swelling and increased light scattering of rod photoreceptors. Proc Natl Acad Sci U S A. 2017 04 04; 114(14):E2937-E2946. Zhang P, Zawadzki RJ, Goswami M, Nguyen PT, Yarov-Yarovoy V, Burns ME, Pugh EN. PMID: 28320964; PMCID: PMC5389324.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    10. Bright flash response recovery of mammalian rods in vivo is rate limited by RGS9. J Gen Physiol. 2017 Apr 03; 149(4):443-454. Peinado Allina G, Fortenbach C, Naarendorp F, Gross OP, Pugh EN, Burns ME. PMID: 28302678; PMCID: PMC5379920.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    11. The Photosensitivity of Rhodopsin Bleaching and Light-Induced Increases of Fundus Reflectance in Mice Measured In Vivo With Scanning Laser Ophthalmoscopy. Invest Ophthalmol Vis Sci. 2016 07 01; 57(8):3650-64. Zhang P, Goswami M, Zawadzki RJ, Pugh EN. PMID: 27403994; PMCID: PMC4959838.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    12. New Developments in Murine Imaging for Assessing Photoreceptor Degeneration In Vivo. Adv Exp Med Biol. 2016; 854:269-75. Burns ME, Levine ES, Miller EB, Zam A, Zhang P, Zawadzki RJ, Pugh EN. PMID: 26427421; PMCID: PMC4603285.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    13. Effect of scanning beam size on the lateral resolution of mouse retinal imaging with SLO. Opt Lett. 2015 Dec 15; 40(24):5830-3. Zhang P, Goswami M, Zam A, Pugh EN, Zawadzki RJ. PMID: 26670523; PMCID: PMC4915368.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    14. Photoreceptor disc morphogenesis: The classical evagination model prevails. J Cell Biol. 2015 Nov 09; 211(3):491-3. Pugh EN. PMID: 26527745; PMCID: PMC4639855.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    15. Wavefront correction and high-resolution in vivo OCT imaging with an objective integrated multi-actuator adaptive lens. Opt Express. 2015 Aug 24; 23(17):21931-41. Bonora S, Jian Y, Zhang P, Zam A, Pugh EN, Zawadzki RJ, Sarunic MV. PMID: 26368169; PMCID: PMC4646522.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    16. In vivo wide-field multispectral scanning laser ophthalmoscopy-optical coherence tomography mouse retinal imager: longitudinal imaging of ganglion cells, microglia, and M�ller glia, and mapping of the mouse retinal and choroidal vasculature. J Biomed Opt. 2015; 20(12):126005. Zhang P, Zam A, Jian Y, Wang X, Li Y, Lam KS, Burns ME, Sarunic MV, Pugh EN, Zawadzki RJ. PMID: 26677070; PMCID: PMC4681314.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    17. Genetic deletion of S-opsin prevents rapid cone degeneration in a mouse model of Leber congenital amaurosis. Hum Mol Genet. 2015 Mar 15; 24(6):1755-63. Zhang T, Enemchukwu NO, Jones A, Wang S, Dennis E, Watt CB, Pugh EN, Fu Y. PMID: 25416279; PMCID: PMC4351380.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    18. Rapid light-induced activation of retinal microglia in mice lacking Arrestin-1. Vision Res. 2014 Sep; 102:71-9. Levine ES, Zam A, Zhang P, Pechko A, Wang X, FitzGerald P, Pugh EN, Zawadzki RJ, Burns ME. PMID: 25091460; PMCID: PMC4162662.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    19. Rhodopsin in the rod surface membrane regenerates more rapidly than bulk rhodopsin in the disc membranes in vivo. J Physiol. 2014 Jul 01; 592(13):2785-97. Kessler C, Tillman M, Burns ME, Pugh EN. PMID: 24801306; PMCID: PMC4221820.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    20. Regulation of rhodopsin-eGFP distribution in transgenic xenopus rod outer segments by light. PLoS One. 2013; 8(11):e80059. Haeri M, Calvert PD, Solessio E, Pugh EN, Knox BE. PMID: 24260336; PMCID: PMC3829889.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    21. Embracing the principles of the San Francisco Declaration of Research Assessment: Robert Balaban's editorial. J Gen Physiol. 2013 Sep; 142(3):175. Pugh EN, Gordon SE. PMID: 23980189; PMCID: PMC3753606.
      View in: PubMed   Mentions: 1     Fields:    
    22. Spotlight summary: quantitative fundus autofluorescence and A2E increase with aging in wild-type and "Stargardt" mice. Invest Ophthalmol Vis Sci. 2013 Apr 23; 54(4):2991. Zawadzki R, Pugh EN. PMID: 23612484; PMCID: PMC6996591.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    23. Cones respond to light in the absence of transducin � subunit. J Neurosci. 2013 Mar 20; 33(12):5182-94. Nikonov SS, Lyubarsky A, Fina ME, Nikonova ES, Sengupta A, Chinniah C, Ding XQ, Smith RG, Pugh EN, Vardi N, Dhingra A. PMID: 23516284; PMCID: PMC3866503.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    24. Scanning laser ophthalmoscope measurement of local fundus reflectance and autofluorescence changes arising from rhodopsin bleaching and regeneration. Invest Ophthalmol Vis Sci. 2013 Mar 01; 54(3):2048-59. Morgan JI, Pugh EN. PMID: 23412087; PMCID: PMC3621503.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    25. Introducing the viewpoint. J Gen Physiol. 2012 Dec; 140(6):579. Pugh EN. PMID: 23183691; PMCID: PMC3514731.
      View in: PubMed   Mentions: 1     Fields:    
    26. Calcium feedback to cGMP synthesis strongly attenuates single-photon responses driven by long rhodopsin lifetimes. Neuron. 2012 Oct 18; 76(2):370-82. Gross OP, Pugh EN, Burns ME. PMID: 23083739; PMCID: PMC3594095.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    27. An S-opsin knock-in mouse (F81Y) reveals a role for the native ligand 11-cis-retinal in cone opsin biosynthesis. J Neurosci. 2012 Jun 06; 32(23):8094-104. Insinna C, Daniele LL, Davis JA, Larsen DD, Kuemmel C, Wang J, Nikonov SS, Knox BE, Pugh EN. PMID: 22674284; PMCID: PMC3381355.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    28. Perspectives on: SGP symposium on mitochondrial physiology and medicine: mitochondria take center stage. J Gen Physiol. 2012 Jun; 139(6):391-3. Sheu SS, Dirksen RT, Pugh EN. PMID: 22641633; PMCID: PMC3362527.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    29. Spatiotemporal cGMP dynamics in living mouse rods. Biophys J. 2012 Apr 18; 102(8):1775-84. Gross OP, Pugh EN, Burns ME. PMID: 22768933; PMCID: PMC3328695.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    30. The 65th Symposium of the Society for General Physiologists: energizing research in mitochondrial physiology and medicine. J Gen Physiol. 2011 Dec; 138(6):563-7. Sheu SS, Dirksen RT, Pugh EN. PMID: 22124113; PMCID: PMC3226972.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    31. Redefining our menu: communications and reviews. J Gen Physiol. 2011 Aug; 138(2):131. Pugh EN. PMID: 21788608; PMCID: PMC3149441.
      View in: PubMed   Mentions:    Fields:    
    32. The 64th Symposium of the Society for General Physiologists: optogenetics and superresolution microscopy take center stage. J Gen Physiol. 2011 Jul; 138(1):1-11. Ellis-Davies GC, Pugh EN. PMID: 21708951; PMCID: PMC3135327.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    33. Good scientists do reach and hold divergent views on important issues. J Gen Physiol. 2011 Mar; 137(3):253. Pugh EN. PMID: 21357731; PMCID: PMC3047605.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    34. A mouse M-opsin monochromat: retinal cone photoreceptors have increased M-opsin expression when S-opsin is knocked out. Vision Res. 2011 Feb 23; 51(4):447-58. Daniele LL, Insinna C, Chance R, Wang J, Nikonov SS, Pugh EN. PMID: 21219924; PMCID: PMC3072795.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    35. We were there... J Gen Physiol. 2010 Nov; 136(5):495. Pugh EN. PMID: 20974770; PMCID: PMC2964518.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    36. Dark light, rod saturation, and the absolute and incremental sensitivity of mouse cone vision. J Neurosci. 2010 Sep 15; 30(37):12495-507. Naarendorp F, Esdaille TM, Banden SM, Andrews-Labenski J, Gross OP, Pugh EN. PMID: 20844144; PMCID: PMC3423338.
      View in: PubMed   Mentions: 89     Fields:    Translation:AnimalsCells
    37. Emerging questions about the macromolecular machines of muscle. J Gen Physiol. 2010 Jul; 136(1):3-5. Dirksen RT, Pugh EN. PMID: 20584886; PMCID: PMC2894551.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    38. Lessons from photoreceptors: turning off g-protein signaling in living cells. Physiology (Bethesda). 2010 Apr; 25(2):72-84. Burns ME, Pugh EN. PMID: 20430952; PMCID: PMC2880230.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    39. Type 3 deiodinase, a thyroid-hormone-inactivating enzyme, controls survival and maturation of cone photoreceptors. J Neurosci. 2010 Mar 03; 30(9):3347-57. Ng L, Lyubarsky A, Nikonov SS, Ma M, Srinivas M, Kefas B, St Germain DL, Hernandez A, Pugh EN, Forrest D. PMID: 20203194; PMCID: PMC2843520.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    40. Diffusion of a soluble protein, photoactivatable GFP, through a sensory cilium. J Gen Physiol. 2010 Mar; 135(3):173-96. Calvert PD, Schiesser WE, Pugh EN. PMID: 20176852; PMCID: PMC2828910.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    41. Enlisting young physiologists. J Gen Physiol. 2009 Dec; 134(6):451-2. Pugh EN. PMID: 19948996; PMCID: PMC2806425.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    42. RGS9 concentration matters in rod phototransduction. Biophys J. 2009 Sep 16; 97(6):1538-47. Burns ME, Pugh EN. PMID: 19751658; PMCID: PMC2749774.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    43. Loss of the metalloprotease ADAM9 leads to cone-rod dystrophy in humans and retinal degeneration in mice. Am J Hum Genet. 2009 May; 84(5):683-91. Parry DA, Toomes C, Bida L, Danciger M, Towns KV, McKibbin M, Jacobson SG, Logan CV, Ali M, Bond J, Chance R, Swendeman S, Daniele LL, Springell K, Adams M, Johnson CA, Booth AP, Jafri H, Rashid Y, Banin E, Strom TM, Farber DB, Sharon D, Blobel CP, Pugh EN, Pierce EA, Inglehearn CF. PMID: 19409519; PMCID: PMC2681008.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    44. Kudos to reviewers for the JGP: you make our science better. J Gen Physiol. 2009 Feb; 133(2):129-30. Pugh EN. PMID: 19171768; PMCID: PMC2638203.
      View in: PubMed   Mentions:    Fields:    
    45. Mouse cones require an arrestin for normal inactivation of phototransduction. Neuron. 2008 Aug 14; 59(3):462-74. Nikonov SS, Brown BM, Davis JA, Zuniga FI, Bragin A, Pugh EN, Craft CM. PMID: 18701071; PMCID: PMC2610856.
      View in: PubMed   Mentions: 90     Fields:    Translation:AnimalsCells
    46. Altered visual function in monocarboxylate transporter 3 (Slc16a8) knockout mice. Am J Physiol Cell Physiol. 2008 Aug; 295(2):C451-7. Daniele LL, Sauer B, Gallagher SM, Pugh EN, Philp NJ. PMID: 18524945; PMCID: PMC2518420.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    47. Models and mechanistic insight. J Gen Physiol. 2008 Jun; 131(6):515-9. Pugh EN, Andersen OS. PMID: 18504312; PMCID: PMC2391249.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    48. Safety and efficacy of gene transfer for Leber's congenital amaurosis. N Engl J Med. 2008 May 22; 358(21):2240-8. Maguire AM, Simonelli F, Pierce EA, Pugh EN, Mingozzi F, Bennicelli J, Banfi S, Marshall KA, Testa F, Surace EM, Rossi S, Lyubarsky A, Arruda VR, Konkle B, Stone E, Sun J, Jacobs J, Dell'Osso L, Hertle R, Ma JX, Redmond TM, Zhu X, Hauck B, Zelenaia O, Shindler KS, Maguire MG, Wright JF, Volpe NJ, McDonnell JW, Auricchio A, High KA, Bennett J. PMID: 18441370; PMCID: PMC2829748.
      View in: PubMed   Mentions: 1004     Fields:    Translation:HumansCellsCTClinical Trials
    49. Nrl-knockout mice deficient in Rpe65 fail to synthesize 11-cis retinal and cone outer segments. Invest Ophthalmol Vis Sci. 2008 Mar; 49(3):1126-35. Feathers KL, Lyubarsky AL, Khan NW, Teofilo K, Swaroop A, Williams DS, Pugh EN, Thompson DA. PMID: 18326740; PMCID: PMC4505835.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    50. Evolution of the vertebrate eye: opsins, photoreceptors, retina and eye cup. Nat Rev Neurosci. 2007 Dec; 8(12):960-76. Lamb TD, Collin SP, Pugh EN. PMID: 18026166; PMCID: PMC3143066.
      View in: PubMed   Mentions: 162     Fields:    Translation:HumansAnimalsCells
    51. Novel distribution of junctional adhesion molecule-C in the neural retina and retinal pigment epithelium. J Comp Neurol. 2007 Nov 10; 505(2):166-76. Daniele LL, Adams RH, Durante DE, Pugh EN, Philp NJ. PMID: 17853450; PMCID: PMC3144860.
      View in: PubMed   Mentions: 29     Fields:    Translation:Animals
    52. The proteome of the mouse photoreceptor sensory cilium complex. Mol Cell Proteomics. 2007 Aug; 6(8):1299-317. Liu Q, Tan G, Levenkova N, Li T, Pugh EN, Rux JJ, Speicher DW, Pierce EA. PMID: 17494944; PMCID: PMC2128741.
      View in: PubMed   Mentions: 208     Fields:    Translation:AnimalsCells
    53. Fluorescence relaxation in 3D from diffraction-limited sources of PAGFP or sinks of EGFP created by multiphoton photoconversion. J Microsc. 2007 Jan; 225(Pt 1):49-71. Calvert PD, Peet JA, Bragin A, Schiesser WE, Pugh EN. PMID: 17286695.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    54. Phototransduction, dark adaptation, and rhodopsin regeneration the proctor lecture. Invest Ophthalmol Vis Sci. 2006 Dec; 47(12):5137-52. Lamb TD, Pugh EN. PMID: 17122096.
      View in: PubMed   Mentions: 119     Fields:    Translation:HumansAnimalsCells
    55. Light-driven translocation of signaling proteins in vertebrate photoreceptors. Trends Cell Biol. 2006 Nov; 16(11):560-8. Calvert PD, Strissel KJ, Schiesser WE, Pugh EN, Arshavsky VY. PMID: 16996267.
      View in: PubMed   Mentions: 139     Fields:    Translation:HumansAnimalsCells
    56. Polarization-based and specular-reflection-based noncontact latent fingerprint imaging and lifting. J Opt Soc Am A Opt Image Sci Vis. 2006 Sep; 23(9):2137-53. Lin SS, Yemelyanov KM, Pugh EN, Engheta N. PMID: 16912740.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    57. RGS expression level precisely regulates the duration of rod photoresponses. Neuron. 2006 Aug 17; 51(4):391-3. Pugh EN. PMID: 16908403.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    58. Separation and contrast enhancement of overlapping cast shadow components using polarization. Opt Express. 2006 Aug 07; 14(16):7099-108. Lin SS, Yemelyanov KM, Pugh EN, Engheta N. PMID: 19529081.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    59. Adaptive algorithms for two-channel polarization sensing under various polarization statistics with nonuniform distributions. Appl Opt. 2006 Aug 01; 45(22):5504-20. Yemelyanov KM, Lin SS, Pugh EN, Engheta N. PMID: 16855649.
      View in: PubMed   Mentions: 3     Fields:    
    60. Physiological features of the S- and M-cone photoreceptors of wild-type mice from single-cell recordings. J Gen Physiol. 2006 Apr; 127(4):359-74. Nikonov SS, Kholodenko R, Lem J, Pugh EN. PMID: 16567464; PMCID: PMC2151510.
      View in: PubMed   Mentions: 190     Fields:    Translation:AnimalsCells
    61. The distribution, concentration, and toxicity of enhanced green fluorescent protein in retinal cells after genomic or somatic (virus-mediated) gene transfer. Mol Vis. 2005 Dec 30; 11:1236-45. Rex TS, Peet JA, Surace EM, Calvert PD, Nikonov SS, Lyubarsky AL, Bendo E, Hughes T, Pugh EN, Bennett J. PMID: 16402024.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    62. Neuroimaging the retina. Vision Res. 2005 Dec; 45(28):3431. Pugh EN, Baehr W, Zrenner E. PMID: 16289207.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    63. Mole quantity of RPE65 and its productivity in the generation of 11-cis-retinal from retinyl esters in the living mouse eye. Biochemistry. 2005 Jul 26; 44(29):9880-8. Lyubarsky AL, Savchenko AB, Morocco SB, Daniele LL, Redmond TM, Pugh EN. PMID: 16026160.
      View in: PubMed   Mentions: 43     Fields:    Translation:Animals
    64. The retinal G protein-coupled receptor (RGR) enhances isomerohydrolase activity independent of light. J Biol Chem. 2005 Aug 19; 280(33):29874-84. Wenzel A, Oberhauser V, Pugh EN, Lamb TD, Grimm C, Samardzija M, Fahl E, Seeliger MW, Remé CE, von Lintig J. PMID: 15961402.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    65. Cone-like morphological, molecular, and electrophysiological features of the photoreceptors of the Nrl knockout mouse. Invest Ophthalmol Vis Sci. 2005 Jun; 46(6):2156-67. Daniele LL, Lillo C, Lyubarsky AL, Nikonov SS, Philp N, Mears AJ, Swaroop A, Williams DS, Pugh EN. PMID: 15914637; PMCID: PMC4505833.
      View in: PubMed   Mentions: 135     Fields:    Translation:AnimalsCells
    66. Photoreceptors of Nrl -/- mice coexpress functional S- and M-cone opsins having distinct inactivation mechanisms. J Gen Physiol. 2005 Mar; 125(3):287-304. Nikonov SS, Daniele LL, Zhu X, Craft CM, Swaroop A, Pugh EN. PMID: 15738050; PMCID: PMC2234018.
      View in: PubMed   Mentions: 89     Fields:    Translation:AnimalsCells
    67. From candelas to photoisomerizations in the mouse eye by rhodopsin bleaching in situ and the light-rearing dependence of the major components of the mouse ERG. Vision Res. 2004 Dec; 44(28):3235-51. Lyubarsky AL, Daniele LL, Pugh EN. PMID: 15535992.
      View in: PubMed   Mentions: 130     Fields:    Translation:AnimalsCells
    68. Deficiency of Bax and Bak protects photoreceptors from light damage in vivo. Cell Death Differ. 2004 Nov; 11(11):1192-7. Hahn P, Lindsten T, Lyubarsky A, Ying GS, Pugh EN, Thompson CB, Dunaief JL. PMID: 15272317.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    69. Quantification of the cytoplasmic spaces of living cells with EGFP reveals arrestin-EGFP to be in disequilibrium in dark adapted rod photoreceptors. J Cell Sci. 2004 Jun 15; 117(Pt 14):3049-59. Peet JA, Bragin A, Calvert PD, Nikonov SS, Mani S, Zhao X, Besharse JC, Pierce EA, Knox BE, Pugh EN. PMID: 15197244.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    70. Dark adaptation and the retinoid cycle of vision. Prog Retin Eye Res. 2004 May; 23(3):307-80. Lamb TD, Pugh EN. PMID: 15177205.
      View in: PubMed   Mentions: 276     Fields:    Translation:HumansAnimalsCells
    71. In utero gene therapy rescues vision in a murine model of congenital blindness. Mol Ther. 2004 Feb; 9(2):182-8. Dejneka NS, Surace EM, Aleman TS, Cideciyan AV, Lyubarsky A, Savchenko A, Redmond TM, Tang W, Wei Z, Rex TS, Glover E, Maguire AM, Pugh EN, Jacobson SG, Bennett J. PMID: 14759802.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    72. RP1 is required for the correct stacking of outer segment discs. Invest Ophthalmol Vis Sci. 2003 Oct; 44(10):4171-83. Liu Q, Lyubarsky A, Skalet JH, Pugh EN, Pierce EA. PMID: 14507858; PMCID: PMC1904498.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimalsCells
    73. Delivery of adeno-associated virus vectors to the fetal retina: impact of viral capsid proteins on retinal neuronal progenitor transduction. J Virol. 2003 Jul; 77(14):7957-63. Surace EM, Auricchio A, Reich SJ, Rex T, Glover E, Pineles S, Tang W, O'Connor E, Lyubarsky A, Savchenko A, Pugh EN, Maguire AM, Wilson JM, Bennett J. PMID: 12829835; PMCID: PMC161923.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    74. Display of polarization information by coherently moving dots. Opt Express. 2003 Jun 30; 11(13):1577-84. Yemelyanov K, Lo M, Pugh E, Engheta N. PMID: 19466033.
      View in: PubMed   Mentions:    Fields:    
    75. Connexin36 forms synapses essential for night vision. Neuron. 2002 Nov 14; 36(4):551-3. Demb JB, Pugh EN. PMID: 12441044.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    76. Massive light-driven translocation of transducin between the two major compartments of rod cells: a novel mechanism of light adaptation. Neuron. 2002 Mar 28; 34(1):95-106. Sokolov M, Lyubarsky AL, Strissel KJ, Savchenko AB, Govardovskii VI, Pugh EN, Arshavsky VY. PMID: 11931744.
      View in: PubMed   Mentions: 175     Fields:    Translation:AnimalsCells
    77. Functionally rodless mice: transgenic models for the investigation of cone function in retinal disease and therapy. Vision Res. 2002 Feb; 42(4):401-15. Lyubarsky AL, Lem J, Chen J, Falsini B, Iannaccone A, Pugh EN. PMID: 11853756.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    78. G proteins and phototransduction. Annu Rev Physiol. 2002; 64:153-87. Arshavsky VY, Lamb TD, Pugh EN. PMID: 11826267.
      View in: PubMed   Mentions: 278     Fields:    Translation:AnimalsCells
    79. A photoreceptor-specific cadherin is essential for the structural integrity of the outer segment and for photoreceptor survival. Neuron. 2001 Dec 06; 32(5):775-86. Rattner A, Smallwood PM, Williams J, Cooke C, Savchenko A, Lyubarsky A, Pugh EN, Nathans J. PMID: 11738025.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    80. Rods are rods and cones cones, and (never) the twain shall meet. Neuron. 2001 Nov 08; 32(3):375-6. Pugh EN. PMID: 11709146.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    81. RGS9-1 is required for normal inactivation of mouse cone phototransduction. Mol Vis. 2001 Mar 20; 7:71-8. Lyubarsky AL, Naarendorp F, Zhang X, Wensel T, Simon MI, Pugh EN. PMID: 11262419.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    82. The light response of ON bipolar neurons requires G[alpha]o. J Neurosci. 2000 Dec 15; 20(24):9053-8. Dhingra A, Lyubarsky A, Jiang M, Pugh EN, Birnbaumer L, Sterling P, Vardi N. PMID: 11124982; PMCID: PMC6773027.
      View in: PubMed   Mentions: 111     Fields:    Translation:AnimalsCells
    83. Phototransduction in transgenic mice after targeted deletion of the rod transducin alpha -subunit. Proc Natl Acad Sci U S A. 2000 12 05; 97(25):13913-8. Calvert PD, Krasnoperova NV, Lyubarsky AL, Isayama T, Nicoló M, Kosaras B, Wong G, Gannon KS, Margolskee RF, Sidman RL, Pugh EN, Makino CL, Lem J. PMID: 11095744; PMCID: PMC17675.
      View in: PubMed   Mentions: 215     Fields:    Translation:AnimalsCells
    84. The role of steady phosphodiesterase activity in the kinetics and sensitivity of the light-adapted salamander rod photoresponse. J Gen Physiol. 2000 Dec; 116(6):795-824. Nikonov S, Lamb TD, Pugh EN. PMID: 11099349; PMCID: PMC2231811.
      View in: PubMed   Mentions: 78     Fields:    Translation:AnimalsCells
    85. The gain of rod phototransduction: reconciliation of biochemical and electrophysiological measurements. Neuron. 2000 Sep; 27(3):525-37. Leskov IB, Klenchin VA, Handy JW, Whitlock GG, Govardovskii VI, Bownds MD, Lamb TD, Pugh EN, Arshavsky VY. PMID: 11055435.
      View in: PubMed   Mentions: 79     Fields:    Translation:AnimalsCells
    86. Transfected cyclic nucleotide-gated channels as biosensors. J Gen Physiol. 2000 Aug; 116(2):143-5. Pugh EN. PMID: 10919862; PMCID: PMC2229490.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    87. Mice lacking G-protein receptor kinase 1 have profoundly slowed recovery of cone-driven retinal responses. J Neurosci. 2000 Mar 15; 20(6):2209-17. Lyubarsky AL, Chen C, Simon MI, Pugh EN. PMID: 10704496; PMCID: PMC6772503.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    88. Molecular mechanisms of vertebrate photoreceptor light adaptation. Curr Opin Neurobiol. 1999 Aug; 9(4):410-8. Pugh EN, Nikonov S, Lamb TD. PMID: 10448166.
      View in: PubMed   Mentions: 137     Fields:    Translation:HumansAnimalsCells
    89. Variability in single photon responses: a cut in the Gordian knot of rod phototransduction? Neuron. 1999 Jun; 23(2):205-8. Pugh EN. PMID: 10399927.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    90. UV- and midwave-sensitive cone-driven retinal responses of the mouse: a possible phenotype for coexpression of cone photopigments. J Neurosci. 1999 Jan 01; 19(1):442-55. Lyubarsky AL, Falsini B, Pennesi ME, Valentini P, Pugh EN. PMID: 9870972; PMCID: PMC6782392.
      View in: PubMed   Mentions: 134     Fields:    Translation:AnimalsCells
    91. Extreme responsiveness of the pupil of the dark-adapted mouse to steady retinal illumination. Invest Ophthalmol Vis Sci. 1998 Oct; 39(11):2148-56. Pennesi ME, Lyubarsky AL, Pugh EN. PMID: 9761294.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    92. Lifetime regulation of G protein-effector complex: emerging importance of RGS proteins. Neuron. 1998 Jan; 20(1):11-4. Arshavsky VY, Pugh EN. PMID: 9459437.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    93. Kinetics of recovery of the dark-adapted salamander rod photoresponse. J Gen Physiol. 1998 Jan; 111(1):7-37. Nikonov S, Engheta N, Pugh EN. PMID: 9417132; PMCID: PMC1887775.
      View in: PubMed   Mentions: 71     Fields:    Translation:AnimalsCells
    94. Photoreceptor guanylate cyclases: a review. Biosci Rep. 1997 Oct; 17(5):429-73. Pugh EN, Duda T, Sitaramayya A, Sharma RK. PMID: 9419388.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    95. Rod plateaux during dark adaptation in Sorsby's fundus dystrophy and vitamin A deficiency. Invest Ophthalmol Vis Sci. 1997 Aug; 38(9):1786-94. Cideciyan AV, Pugh EN, Lamb TD, Huang Y, Jacobson SG. PMID: 9286267.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    96. Olfactory adaptation. The nose leads the eye. Nature. 1997 Feb 20; 385(6618):677, 679. Gold GH, Pugh EN. PMID: 9034182.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    97. Phospholipase C beta 4 is involved in modulating the visual response in mice. Proc Natl Acad Sci U S A. 1996 Dec 10; 93(25):14598-601. Jiang H, Lyubarsky A, Dodd R, Vardi N, Pugh E, Baylor D, Simon MI, Wu D. PMID: 8962098; PMCID: PMC26179.
      View in: PubMed   Mentions: 51     Fields:    Translation:Animals
    98. Target detection in optically scattering media by polarization-difference imaging. Appl Opt. 1996 Apr 10; 35(11):1855-70. Tyo JS, Rowe MP, Pugh EN, Engheta N. PMID: 21085310.
      View in: PubMed   Mentions: 9     Fields:    
    99. Monogeusia for fructose, glucose, sucrose, and maltose. Percept Psychophys. 1996 Apr; 58(3):327-41. Breslin PA, Beauchamp GK, Pugh EN. PMID: 8935894.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    100. Cooperativity in cyclic nucleotide-gated ion channels. J Gen Physiol. 1996 Feb; 107(2):165-7. Pugh EN. PMID: 8833338; PMCID: PMC2219271.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    101. Recovery phase of the murine rod photoresponse reconstructed from electroretinographic recordings. J Neurosci. 1996 Jan 15; 16(2):563-71. Lyubarsky AL, Pugh EN. PMID: 8551340; PMCID: PMC6578659.
      View in: PubMed   Mentions: 112     Fields:    Translation:AnimalsCells
    102. The effect of light history on the aspartate-isolated fast-PIII responses of the albino rat retina. Invest Ophthalmol Vis Sci. 1996 Jan; 37(1):221-9. Reiser MA, Williams TP, Pugh EN. PMID: 8550327.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    103. The kinetics of inactivation of the rod phototransduction cascade with constant Ca2+i. J Gen Physiol. 1996 Jan; 107(1):19-34. Lyubarsky A, Nikonov S, Pugh EN. PMID: 8741728; PMCID: PMC2219253.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    104. Rod outer segment structure influences the apparent kinetic parameters of cyclic GMP phosphodiesterase. J Gen Physiol. 1994 Jun; 103(6):1071-98. Dumke CL, Arshavsky VY, Calvert PD, Bownds MD, Pugh EN. PMID: 7931138; PMCID: PMC2216889.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    105. Graded-index model of a fish double cone exhibits differential polarization sensitivity. J Opt Soc Am A Opt Image Sci Vis. 1994 Jan; 11(1):55-70. Rowe MP, Engheta N, Easter SS, Pugh EN. PMID: 8106915.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    106. Analysis of ERG a-wave amplification and kinetics in terms of the G-protein cascade of phototransduction. Invest Ophthalmol Vis Sci. 1994 Jan; 35(1):295-309. Breton ME, Schueller AW, Lamb TD, Pugh EN. PMID: 8300357.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCells
    107. Diffusion coefficient of cyclic GMP in salamander rod outer segments estimated with two fluorescent probes. Biophys J. 1993 Sep; 65(3):1335-52. Olson A, Pugh EN. PMID: 8241412; PMCID: PMC1225852.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    108. Strange case of the third eye. Nature. 1993 Jul 29; 364(6436):389-90. Pugh EN, Lisman J, Payne R. PMID: 8332207.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    109. Amplification and kinetics of the activation steps in phototransduction. Biochim Biophys Acta. 1993 Mar 01; 1141(2-3):111-49. Pugh EN, Lamb TD. PMID: 8382952.
      View in: PubMed   Mentions: 245     Fields:    Translation:HumansAnimalsCells
    110. Monochromatism determined at a long-wavelength/middle-wavelength cone-antagonistic locus. Vision Res. 1992 Dec; 32(12):2349-67. Calkins DJ, Thornton JE, Pugh EN. PMID: 1288011.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    111. G-protein cascades: gain and kinetics. Trends Neurosci. 1992 Aug; 15(8):291-8. Lamb TD, Pugh EN. PMID: 1384198.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    112. A quantitative account of the activation steps involved in phototransduction in amphibian photoreceptors. J Physiol. 1992 Apr; 449:719-58. Lamb TD, Pugh EN. PMID: 1326052; PMCID: PMC1176104.
      View in: PubMed   Mentions: 241     Fields:    Translation:AnimalsCells
    113. Double cones as a basis for a new type of polarization vision in vertebrates. Nature. 1991 Sep 12; 353(6340):161-4. Cameron DA, Pugh EN. PMID: 1891046.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    114. The magnitude, time course and spatial distribution of current induced in salamander rods by cyclic guanine nucleotides. J Physiol. 1990 Nov; 430:419-39. Cameron DA, Pugh EN. PMID: 1964967; PMCID: PMC1181745.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    115. Calcium inhibition of ATP-dependent inactivation of rod disk phosphodiesterase in isolated rods and membrane suspensions. Neurosci Res Suppl. 1990; 12:S183-90. Pugh EN, Cobbs WH, Barkdoll AE. PMID: 2243635.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    116. Cyclic GMP and calcium: the internal messengers of excitation and adaptation in vertebrate photoreceptors. Vision Res. 1990; 30(12):1923-48. Pugh EN, Lamb TD. PMID: 1962979.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    117. Calcium dependence of the activation and inactivation kinetics of the light-activated phosphodiesterase of retinal rods. J Gen Physiol. 1989 Jun; 93(6):1091-108. Barkdoll AE, Pugh EN, Sitaramayya A. PMID: 2549175; PMCID: PMC2216249.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    118. Phototransduction. A role for calcium in adaptation. Nature. 1988 Jul 07; 334(6177):16-7. Pugh E, Altman J. PMID: 2455232.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    119. Kinetics of the hydrolysis of 8-bromo-cyclic GMP by the light-activated phosphodiesterase of toad rods. J Neurochem. 1988 Mar; 50(3):839-46. Barkdoll AE, Pugh EN, Sitaramayya A. PMID: 2828548.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    120. Kinetics and components of the flash photocurrent of isolated retinal rods of the larval salamander, Ambystoma tigrinum. J Physiol. 1987 Dec; 394:529-72. Cobbs WH, Pugh EN. PMID: 2832596; PMCID: PMC1191975.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    121. The nature and identity of the internal excitational transmitter of vertebrate phototransduction. Annu Rev Physiol. 1987; 49:715-41. Pugh EN. PMID: 3032080.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    122. Special topic: phototransduction in vertebrates. General introduction. Annu Rev Physiol. 1987; 49:711-4. Pugh EN, Miller WH. PMID: 3566215.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    123. The pi mechanisms of W S Stiles: an historical review. Perception. 1986; 15(6):705-28. Pugh EN, Kirk DB. PMID: 3309877.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    124. Visual transduction in vertebrate rods and cones: a tale of two transmitters, calcium and cyclic GMP. Vision Res. 1986; 26(10):1613-43. Pugh EN, Cobbs WH. PMID: 2441524.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    125. Cyclic GMP increases photocurrent and light sensitivity of retinal cones. Nature. 1985 Sep 5-11; 317(6032):64-6. Cobbs WH, Barkdoll AE, Pugh EN. PMID: 2993915.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    126. Cyclic GMP can increase rod outer-segment light-sensitive current 10-fold without delay of excitation. Nature. 1985 Feb 14-20; 313(6003):585-7. Cobbs WH, Pugh EN. PMID: 2982108.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    127. Cone antagonism along visual pathways of red/green dichromats. Vision Res. 1985; 25(11):1647-54. Friedman LJ, Thornton JE, Pugh EN. PMID: 3879568.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    128. Protons suppress the dark current of frog retinal rods. J Physiol. 1984 Feb; 347:85-110. Liebman PA, Mueller P, Pugh EN. PMID: 6608584; PMCID: PMC1199436.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    129. Temporal integration of the pi 1/pi 3 pathway in normal and dichromatic vision. Vision Res. 1984; 24(7):743-50. Friedman LJ, Yim MH, Pugh EN. PMID: 6331680.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    130. Protons block the dark current of isolated retinal rods. Proc Natl Acad Sci U S A. 1983 Apr; 80(7):1892-6. Mueller P, Pugh EN. PMID: 6300877; PMCID: PMC393716.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    131. Red/Green color opponency at detection threshold. Science. 1983 Jan 14; 219(4581):191-3. Thornton JE, Pugh EN. PMID: 6849131.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    132. Gain, speed and sensitivity of GTP binding vs PDE activation in visual excitation. Vision Res. 1982; 22(12):1475-80. Liebman PA, Pugh EN. PMID: 6305023.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    133. ATP mediates rapid reversal of cyclic GMP phosphodiesterase activation in visual receptor membranes. Nature. 1980 Oct 23; 287(5784):734-6. Liebman PA, Pugh EN. PMID: 6107856.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    134. A field-additive pathway detects brief-duration, long-wavelength incremental flashes. Vision Res. 1980; 20(7):613-24. Wandell BA, Pugh EN. PMID: 7434596.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    135. Detection of long-duration, long-wavelength incremental flashes by a chromatically coded pathway. Vision Res. 1980; 20(7):625-36. Wandell BA, Pugh EN. PMID: 7434597.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    136. Test of the identity of the site of blue/yellow hue cancellation and the site of chromatic antagonism in the pi 1 pathway. Vision Res. 1980; 20(9):779-88. Pugh EN, Larimer J. PMID: 7456339.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    137. Stiles's II5 color mechanism: tests of field displacement and field additivity properties. J Opt Soc Am. 1980 Jan; 70(1):71-81. Sigel C, Pugh EN. PMID: 7411265.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    138. A theory of the pi1 and pi3 color mechanisms of Stiles. Vision Res. 1979; 19(3):293-312. Pugh EN, Mollon JD. PMID: 444331.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    139. The control of phosphodiesterase in rod disk membranes: kinetics, possible mechanisms and significance for vision. Vision Res. 1979; 19(4):375-80. Liebman PA, Pugh EN. PMID: 224596.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    140. Evaluation of the candidacy of the pi-mechanisms of Stiles for color-matching fundamentals. Vision Res. 1978; 18(3):317-30. Pugh EN, Sigel C. PMID: 664305.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    141. The dynamics of the pi 1 colour mechanism: further evidence for two sites of adaptation. J Physiol. 1977 Nov; 272(2):247-81. Augenstein EJ, Pugh EN. PMID: 592192; PMCID: PMC1353557.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    142. Variation in the action spectrum of erythrolabe among deuteranopes. J Physiol. 1977 Apr; 266(3):613-46. Alpern M, Pugh EN. PMID: 301186; PMCID: PMC1283583.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    143. The nature of the pi1 colour mechanism of W.S. Stiles. J Physiol. 1976 Jun; 257(3):713-47. Pugh EN. PMID: 950611; PMCID: PMC1309388.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    144. Altered ocular pigments, photostable and labile: two causes of deuteranomalous trichromacy. Mod Probl Ophthalmol. 1976; 17:273-91. Alpern M, Bastian B, Pugh EN, Gras W. PMID: 1085880.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    145. Rhodopsin flash photolysis in man. J Physiol. 1975 Jun; 248(2):393-412. Pugh EN. PMID: 1151790; PMCID: PMC1309529.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    146. Rushton's paradox: rod dark adaptation after flash photolysis. J Physiol. 1975 Jun; 248(2):413-31. Pugh EN. PMID: 1151791; PMCID: PMC1309530.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    147. The density and photosensitivity of human rhodopsin in the living retina. J Physiol. 1974 Mar; 237(2):341-70. Alpern M, Pugh EN. PMID: 4825455; PMCID: PMC1350887.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells